8-K
0000728387false00007283872026-06-012026-06-01

 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): June 01, 2026

 

 

Perspective Therapeutics, Inc.

(Exact name of Registrant as Specified in Its Charter)

 

 

Delaware

001-33407

41-1458152

(State or Other Jurisdiction
of Incorporation)

(Commission File Number)

(IRS Employer
Identification No.)

 

 

 

 

 

c/o Perspective Therapeutics, Inc.

2401 Elliott Avenue

Suite 320

 

Seattle, Washington

 

98121

(Address of Principal Executive Offices)

 

(Zip Code)

 

Registrant’s Telephone Number, Including Area Code: (206) 676-0900

 

 

(Former Name or Former Address, if Changed Since Last Report)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:


Title of each class

 

Trading
Symbol(s)

 


Name of each exchange on which registered

Common Stock, $0.001 par value

 

CATX

 

NYSE American LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

 


Item 8.01 Other Events.

On June 1, 2026, Perspective Therapeutics, Inc. updated its corporate presentation. A copy of the presentation is filed as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference into this Item 8.01.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

 

Exhibit No.

 

Description

99.1

 

Corporate Presentation.

104

 

Cover Page Interactive Data File (embedded within the Inline XBRL document).

 


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

PERSPECTIVE THERAPEUTICS, INC.

 

 

 

 

Date:

June 1, 2026

By:

/s/ Joel Sendek

 

 

 

Joel Sendek
Chief Financial Officer

 


Slide 1

Redefining Oncology Treatment with Next-Generation Radiopharmaceuticals


Slide 2

 


Slide 3

Engineering the Alpha Advantage in Targeted Oncology


Slide 4

Unlocking New Treatment Options Across Solid Tumors:


Slide 5

Optimizing the Entire System


Slide 6

Rapidly Advancing Best-in-Class Next Generation Radiopharmaceuticals


Slide 7

Optimizing Structural Chemistry:


Slide 8

Choosing The Right Isotope


Slide 9

Not All ²¹²Pb Programs Are Created Equal


Slide 10

 


Slide 11

Advancing a Theranostic Approach:


Slide 12

Solid Tumors are an Attractive Market for Radiopharmaceuticals


Slide 13

Expanding the Addressable Market


Slide 14

Direct-to-Hospital Delivery through Integrated Isotope Production


Slide 15

Daily Production at Regional Sites Ensures Supply of Ready-to-Administer Product


Slide 16

Reaching the Largest Addressable Market with Regional Manufacturing


Slide 17

Advancing a Diverse Wholly Owned 212Pb-Based Oncology Portfolio


Slide 18

SSTR2+ Neuroendocrine Tumors is a Large, Growing Market with Significant Unmet Need


Slide 19

VMT-⍺-NET: Potential First-in-Class 212Pb-Radioligand Therapy Targeting SSTR2


Slide 20

Ongoing Phase 1/2a to Establish Broad Therapeutic Window For VMT-⍺-NET in NETs


Slide 21

VMT-⍺-NET: Baseline Patient Characteristics in ASCO 2026 Data Analysis


Slide 22

Patient Exposure and Follow-up with [212Pb]VMT-α-NET in ASCO 2026 Data Analysis


Slide 23

VMT-α-NET Responses Deepen Over Time


Slide 24

VMT-⍺-NET: Durable Disease Control Across All Doses


Slide 25

Spider Plot of Tumor Change Over Time by Patient


Slide 26

Best-in-class Safety Profile1


Slide 27

Blood Creatinine During Follow-up for All Patients Treated (n=68)


Slide 28

VMT-α-NET’s Compelling Profile Supports Potential Registration Study at Current Dose Level


Slide 29

Checkpoint Inhibitors Transformed Care of Melanoma but Leave Many Patients Behind


Slide 30

VMT01: Potential First-in-Class 212Pb Therapy Targeting MC1R for Melanoma


Slide 31

Ongoing Phase 1/2a Open-Label Trial For VMT01 in Melanoma


Slide 32

Preliminary Anti-tumor Activity Observed at 3.0 mCi Dose of VMT01


Slide 33

Treatment Emergent Adverse Events (All Grades, Occurring in ≥ 10% of Patients)


Slide 34

VMT01 is Well-tolerated with Initial Anti-tumor Activity Supporting Further Development


Slide 35

FAP-ɑ is an Attractive Cancer Target with Broad Solid Tumor Potential


Slide 36

PSV359: Potential First-in-Class 212Pb Therapy Targeting FAP-ɑ for Solid Tumors


Slide 37

Ongoing Open-label Phase 1/2a Trial For PSV359 in Advanced Solid Tumors


Slide 38

PSV359 has Improved Tumor Retention, Highlighting its Potential as a Therapeutic Agent


Slide 39

Strong IP Portfolio Covering All Aspects of Radiopharmaceutical Value Chain


Slide 40

 


Slide 41

A Decade of Deliberate, End-to-End Engineering


Slide 42

Built Over a Decade:


Slide 43

 


Slide 44

Abbreviations


Slide 45

APPENDIX


Slide 46

 


Slide 47

NETs Trials


Slide 48

Patient with Confirmed PR After [212Pb]VMT-α-NET Treatment


Slide 49

Refractory Metastatic Melanoma Trials


Slide 50

ICI Combo Rationale: Strong Synergy with [212Pb]VMT01 in Melanoma


Slide 51

 


Slide 52

 


Slide 53

Construct designed for better clinical outcome


Slide 54

212Pb Uniquely Suited for Combination with Immune Check Point Inhibitors


Slide 55

 


Slide 56