8-K
0000728387false00007283872026-02-022026-02-02

 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): February 02, 2026

 

 

Perspective Therapeutics, Inc.

(Exact name of Registrant as Specified in Its Charter)

 

 

Delaware

001-33407

41-1458152

(State or Other Jurisdiction
of Incorporation)

(Commission File Number)

(IRS Employer
Identification No.)

 

 

 

 

 

c/o Perspective Therapeutics, Inc.

2401 Elliott Avenue

Suite 320

 

Seattle, Washington

 

98121

(Address of Principal Executive Offices)

 

(Zip Code)

 

Registrant’s Telephone Number, Including Area Code: (206) 676-0900

 

 

(Former Name or Former Address, if Changed Since Last Report)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:


Title of each class

 

Trading
Symbol(s)

 


Name of each exchange on which registered

Common Stock, $0.001 par value

 

CATX

 

NYSE American LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

 


Item 2.02 Results of Operations and Financial Condition.

On February 2, 2026, Perspective Therapeutics, Inc. (the "Company") updated its corporate presentation (the "Presentation"). The Presentation contains certain estimated and projected financial information, including the Company’s estimated cash, cash equivalents and short-term investments as of December 31, 2025. The estimated and projected financial information included in the Presentation is preliminary and has not been audited, reviewed or compiled by the Company’s independent registered public accounting firm, WithumSmith+Brown, PC (“Withum”), and Withum has not performed any procedures with respect to the preliminary financial data. Accordingly, Withum does not express an opinion or any other form of assurance with respect thereto.

The Company’s actual results as of December 31, 2025 may differ from the preliminary financial data due to the completion of the Company’s closing procedures with respect to the year ended December 31, 2025, final adjustments and other developments that may arise between now and the time the financial results for the fiscal year are finalized.

Item 8.01 Other Events.

On February 2, 2026, the Company posted the Presentation to its website. A copy of the Presentation is filed herewith as Exhibit 99.1 and is incorporated by reference into this Item 8.01.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

 

Exhibit No.

 

Description

99.1

 

Corporate Presentation.

104

 

Cover Page Interactive Data File (embedded within the Inline XBRL document).

 


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

PERSPECTIVE THERAPEUTICS, INC.

 

 

 

 

Date:

February 2, 2026

By:

/s/ Joel Sendek

 

 

 

Joel Sendek
Chief Financial Officer

 


Redefining Oncology Treatment with Next-Generation Radiopharmaceuticals


 


Why Radiotherapy, Why Perspective: Realizing the Untapped Value Across Oncology


Rapidly Advancing Best-in-Class Next Generation Radiopharmaceuticals


Proprietary Radioligand Platform Optimizes Therapeutic Index


Proprietary Pb-Based Chelator Designed for Broader and Safer Use


Lead-212: Optimal Isotope with Advantages Over Beta and Other Alpha Emitters


Imaging Optimizes Targeted Delivery to Tumor


 


Solid Tumors are an Attractive Market for Radiopharmaceuticals


End-to-End Manufacturing with Clinical Supply Secured and Commercial Scale Underway


Advancing a Diverse Wholly Owned 212Pb-Based Oncology Portfolio


SSTR2+ Neuroendocrine Tumors is a Large, Growing Market with Significant Unmet Need


VMT-⍺-NET: Potential First-in-Class 212Pb-Radioligand Therapy Targeting SSTR2


Ongoing Phase 1/2a to Establish Broad Therapeutic Window For VMT-⍺-NET in NETs


Compelling Anti-tumor Activity with Sustained or Deepening Responses


VMT-⍺-NET: Durable Disease Control Across All Doses


Best-in-class Safety Profile1


VMT-⍺-NET: Select Adverse Events of Special Interest


VMT-α-NET’s Compelling Profile Supports Potential Registration Study at Current Dose Level


Checkpoint Inhibitors Transformed Care of Melanoma but Leave Many Patients Behind


VMT01: Potential First-in-Class 212Pb Therapy Targeting MC1R for Melanoma


Ongoing Phase 1/2a Open-Label Trial For VMT01 in Melanoma


Preliminary Anti-tumor Activity Observed at Lower Dose of VMT01


Treatment Emergent Adverse Events (All Grades, Occurring in ≥ 2 Patients)


VMT01 is Well-tolerated with Initial Anti-tumor Activity Supporting Further Development


FAP-ɑ is an Attractive Cancer Target with Broad Solid Tumor Potential


PSV359: Potential First-in-Class 212Pb Therapy Targeting FAP-ɑ for Solid Tumors


Ongoing Open-label Phase 1/2a Trial For PSV359 in Advanced Solid Tumors


PSV359 has Improved Tumor Retention, Highlighting its Potential as a Therapeutic Agent


Strong IP Portfolio Covering All Aspects of Radiopharmaceutical Value Chain


 


Phase 1/2 Data Expected Across All 3 Clinical Programs in 2026


 


Abbreviations


APPENDIX


 


NETs Trials


VMT-⍺-NET: Baseline Patient Characteristics in ASCO-GI 2026 Data Analysis


Patient Exposure and Follow-up with [212Pb]VMT-α-NET in ASCO-GI 2026 Data Analysis


VMT-⍺-NET: Durable Disease Control Across All Doses


VMT-⍺-NET: Signal of Sustained Anti-tumor Activity


Patient with Confirmed PR After [212Pb]VMT-α-NET Treatment


Blood Creatinine During Follow-up for All Patients Treated (n=56)


Refractory Metastatic Melanoma Trials


ICI Combo Rationale: Strong Synergy with [212Pb]VMT01 in Melanoma


 


 


Perspective’s proprietary chelator has been optimized for lead-based RPTs