| (State or other jurisdiction of incorporation) | (Commission File Number) | (IRS Employer Identification No.) | ||||||||||||
| Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) | |||||
| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) | |||||
| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) | |||||
| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) | |||||
| Title of each class | Trading Symbol(s) | Name of each exchange on which registered | ||||||||||||
| Exhibit Number | Description | |||||||
| 99.1 | ||||||||
| 104 | Cover Page Interactive Data File (embedded within the Inline XBRL document). | |||||||
| MYRIAD GENETICS, INC. | ||||||||
| Date: May 6, 2025 | By: | /s/ Scott J. Leffler | ||||||
| Scott J. Leffler | ||||||||
| Chief Financial Officer | ||||||||

| Three Months Ended March 31, | |||||||||||||||||
| (in thousands) | 2025 | 2024 | % Change | ||||||||||||||
Product volumes: | |||||||||||||||||
Hereditary cancer | 73 | 71 | 3 | % | |||||||||||||
Tumor profiling(1) | 12 | 14 | (14) | % | |||||||||||||
| Prenatal | 173 | 172 | 1 | % | |||||||||||||
Pharmacogenomics | 127 | 124 | 2 | % | |||||||||||||
| Total | 385 | 381 | 1 | % | |||||||||||||
(1) Tumor Profiling decreased for the three months ended March 31, 2025 compared to the same period in the prior year due primarily to a decrease in testing volume for EndoPredict due to the sale of the company's international EndoPredict business in August 2024. | |||||||||||||||||
| Three Months Ended March 31, | |||||||||||||||||
(in millions) | 2025 | 2024 | % Change | ||||||||||||||
Product revenues: | |||||||||||||||||
Hereditary cancer | $ | 86.3 | $ | 88.1 | (2) | % | |||||||||||
Tumor profiling(1) | 29.3 | 30.9 | (5) | % | |||||||||||||
| Prenatal | 49.3 | 44.3 | 11 | % | |||||||||||||
Pharmacogenomics | 31.0 | 38.9 | (20) | % | |||||||||||||
| Total | $ | 195.9 | $ | 202.2 | (3) | % | |||||||||||
(1) Tumor Profiling decreased for the three months ended March 31, 2025 compared to the same period in the prior year due primarily to a decrease in testing volume for EndoPredict due to the sale of the company's international EndoPredict business in August 2024. | |||||||||||||||||
| (in millions, except per share amounts) | INITIAL 2025 Guidance | CURRENT 2025 Guidance | FY 2025 Comments | ||||||||||||||
| Revenue | $840 - $860 | $807 - $823 | Lowered 2025 revenue range mid-point by $35 million reflecting an updated outlook for our pharmacogenomics business and hereditary cancer testing in our Women's Health business. | ||||||||||||||
Gross Margin % | 69.5% - 70.5% | 68.5% - 69.5% | Gross margins expected to fluctuate in any quarter given product mix and pricing trends. | ||||||||||||||
Adjusted Operating Expenses | $575 - $595 | $555 - $565 | Change reflects moderating planned expenditures for remainder of 2025. | ||||||||||||||
| Adjusted EBITDA** | $25 - $35 | $19 - $27 | |||||||||||||||
| Adjusted EPS*** | $0.07 - $0.11 | $(0.02) - $0.02 | |||||||||||||||
| * | Assumes currency rates as of May 6, 2025. | ||||||||||||||||
| ** | Adjusted EBITDA is defined as Net Income (loss) plus income tax expense (benefit), total other income (expense), non-cash operating expenses, such as amortization of intangible assets, depreciation, impairment of long-lived assets, and share-based compensation expense, and one-time expenses such as expenses from real estate optimization initiatives, transformation initiatives, legal settlements, and divestitures and acquisitions. | ||||||||||||||||
| *** | Full-year 2025 adjusted EPS is based on a 94 million share count. | ||||||||||||||||
| Three months ended March 31, | |||||||||||||||||||||||||||||||||||
| (in millions) | 2025 | 2024 | |||||||||||||||||||||||||||||||||
| WH | ONC | PGx | Total | WH | ONC | PGx | Total | % Change | |||||||||||||||||||||||||||
| Hereditary Cancer | $ | 37.9 | $ | 48.4 | $ | — | $ | 86.3 | $ | 39.6 | $ | 48.5 | $ | — | $ | 88.1 | (2) | % | |||||||||||||||||
| Tumor Profiling | — | 29.3 | — | 29.3 | — | 30.9 | — | 30.9 | (5) | % | |||||||||||||||||||||||||
| Prenatal | 49.3 | — | — | 49.3 | 44.3 | — | — | 44.3 | 11 | % | |||||||||||||||||||||||||
| Pharmacogenomics | — | — | 31.0 | 31.0 | — | — | 38.9 | 38.9 | (20) | % | |||||||||||||||||||||||||
| Total Revenue | $ | 87.2 | $ | 77.7 | $ | 31.0 | $ | 195.9 | $ | 83.9 | $ | 79.4 | $ | 38.9 | $ | 202.2 | (3) | % | |||||||||||||||||
| Three months ended March 31, | |||||||||||
| 2025 | 2024 | ||||||||||
| Revenue | $ | 195.9 | $ | 202.2 | |||||||
| Cost of revenue | 61.7 | 64.6 | |||||||||
| Gross profit | 134.2 | 137.6 | |||||||||
| Operating expenses: | |||||||||||
| Research and development expense | 27.5 | 24.9 | |||||||||
| Sales and marketing expense | 69.2 | 69.4 | |||||||||
| General and administrative expense | 66.5 | 71.2 | |||||||||
| Total operating expenses | 163.2 | 165.5 | |||||||||
| Operating loss | (29.0) | (27.9) | |||||||||
| Other income (expense): | |||||||||||
| Interest income | 0.3 | 0.6 | |||||||||
| Interest expense | (0.8) | (0.5) | |||||||||
| Other | 0.1 | 1.9 | |||||||||
| Total other income (expense) | (0.4) | 2.0 | |||||||||
| Loss before income tax | (29.4) | (25.9) | |||||||||
| Income tax (benefit) expense | (29.3) | 0.1 | |||||||||
| Net loss | $ | (0.1) | $ | (26.0) | |||||||
| Net loss per share: | |||||||||||
| Basic and Diluted | $ | — | $ | (0.29) | |||||||
| Weighted average shares outstanding: | |||||||||||
| Basic and Diluted | 91.4 | 89.9 | |||||||||
| March 31, 2025 | December 31, 2024 | ||||||||||
| ASSETS | |||||||||||
| Current assets: | |||||||||||
| Cash and cash equivalents | $ | 91.8 | $ | 102.4 | |||||||
| Trade accounts receivable | 120.4 | 121.2 | |||||||||
| Inventory | 28.3 | 27.5 | |||||||||
| Prepaid taxes | 14.3 | 16.4 | |||||||||
| Prepaid expenses and other current assets | 32.4 | 30.5 | |||||||||
| Total current assets | 287.2 | 298.0 | |||||||||
| Operating lease right-of-use assets | 53.4 | 55.0 | |||||||||
| Property, plant and equipment, net | 114.0 | 117.4 | |||||||||
| Intangibles, net | 257.5 | 262.4 | |||||||||
| Goodwill | 286.3 | 286.3 | |||||||||
| Other assets | 7.7 | 8.5 | |||||||||
| Total assets | $ | 1,006.1 | $ | 1,027.6 | |||||||
| LIABILITIES AND STOCKHOLDERS' EQUITY | |||||||||||
| Current liabilities: | |||||||||||
| Accounts payable | $ | 28.1 | $ | 32.3 | |||||||
| Accrued liabilities | 112.1 | 119.0 | |||||||||
| Current maturities of operating lease liabilities | 10.9 | 12.8 | |||||||||
| Total current liabilities | 151.1 | 164.1 | |||||||||
| Unrecognized tax benefits | 1.4 | 32.7 | |||||||||
| Long-term debt | 59.3 | 39.6 | |||||||||
| Noncurrent operating lease liabilities | 87.4 | 87.9 | |||||||||
| Other long-term liabilities | 2.0 | 2.2 | |||||||||
| Total liabilities | 301.2 | 326.5 | |||||||||
| Commitments and contingencies | |||||||||||
| Stockholders’ equity: | |||||||||||
Common stock, 92.2 and 91.3 shares outstanding at March 31, 2025 and December 31, 2024, respectively | 0.9 | 0.9 | |||||||||
| Additional paid-in capital | 1,461.5 | 1,457.8 | |||||||||
| Accumulated other comprehensive loss | (0.6) | (0.8) | |||||||||
| Accumulated deficit | (756.9) | (756.8) | |||||||||
| Total stockholders' equity | 704.9 | 701.1 | |||||||||
| Total liabilities and stockholders’ equity | $ | 1,006.1 | $ | 1,027.6 | |||||||
| Three months ended March 31, | |||||||||||
| 2025 | 2024 | ||||||||||
| Net cash used in operating activities | $ | (16.3) | $ | (18.6) | |||||||
| Net cash used in investing activities | (8.3) | (7.1) | |||||||||
| Net cash provided by (used in) financing activities | 13.6 | (8.8) | |||||||||
| Effect of foreign exchange rates on cash, cash equivalents, and restricted cash | 0.1 | (0.8) | |||||||||
| Net decrease in cash, cash equivalents, and restricted cash | (10.9) | (35.3) | |||||||||
| Cash, cash equivalents, and restricted cash at beginning of the period | 111.9 | 140.9 | |||||||||
| Cash, cash equivalents, and restricted cash at end of the period | $ | 101.0 | $ | 105.6 | |||||||
Investor Contact | ||
| Matt Scalo | ||
| (801) 584-3532 | ||
Media Contact | ||
| Kate Schraml | ||
| (224) 875-4493 | ||
| Three Months Ended March 31, | ||||||||||||||
| 2025 | 2024 | |||||||||||||
| Adjusted Gross Margin | ||||||||||||||
| Gross Profit | $ | 134.2 | $ | 137.6 | ||||||||||
Acquisition - amortization of intangible assets(1) | 0.3 | 0.3 | ||||||||||||
Equity compensation(2) | 0.3 | 0.3 | ||||||||||||
Other adjustments(3) | 0.3 | 0.3 | ||||||||||||
| Adjusted Gross Profit | $ | 135.1 | $ | 138.5 | ||||||||||
| Adjusted Gross Margin | 69.0 | % | 68.5 | % | ||||||||||
| (1) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||||||||
| (2) | Consists of the non-cash equity-based compensation provided to Myriad Genetics employees. | |||||||||||||
| (3) | Other one-time non-recurring expenses for the three months ended March 31, 2025 and March 31, 2024. | |||||||||||||
| Three Months Ended March 31, | ||||||||||||||
| 2025 | 2024 | |||||||||||||
| Adjusted Operating Expenses | ||||||||||||||
| Operating Expenses | $ | 163.2 | $ | 165.5 | ||||||||||
Acquisition - amortization of intangible assets(1) | (8.8) | (10.4) | ||||||||||||
Equity compensation(2) | (9.2) | (11.6) | ||||||||||||
Real estate optimization(3) | (3.0) | (1.2) | ||||||||||||
Transformation initiatives(4) | — | (1.9) | ||||||||||||
Legal settlements(5) | — | 0.1 | ||||||||||||
Other adjustments(6) | (1.6) | (1.4) | ||||||||||||
| Adjusted Operating Expenses | $ | 140.6 | $ | 139.1 | ||||||||||
| (1) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||||||||
| (2) | Consists of the non-cash equity-based compensation provided to Myriad Genetics employees and directors. | |||||||||||||
| (3) | Costs related to real estate initiatives. For the three months ended March 31, 2025, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South San Francisco, California, while maintaining our current laboratories in those locations and testing and set-up costs for equipment in our new facilities. For the three months ended March 31, 2024, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South Francisco, California, while maintaining our current laboratories in those locations, costs associated with the voluntary termination of a lease, testing and set-up costs for equipment in our new facilities, and impairment in connection with the ceased use of one of our facilities. | |||||||||||||
| (4) | Costs related to transformation initiatives including consulting and professional fees for the three months ended March 31, 2024. | |||||||||||||
| (5) | Costs related to one-time legal expenses, net of reimbursement for the three months ended March 31, 2024. | |||||||||||||
| (6) | Other one-time non-recurring expenses. For the three months ended March 31, 2025, consists primarily of severance related costs. For the three months ended March 31, 2024, primarily includes a gain recognized on acquisition, changes in the fair value of contingent consideration related to acquisitions from prior years, the reclassifications of cumulative translation adjustments to income upon liquidation of an investment in a foreign entity, and costs incurred in connection with executive personnel changes. | |||||||||||||
| Three Months Ended March 31, | ||||||||||||||
| 2025 | 2024 | |||||||||||||
| Adjusted Operating Loss | ||||||||||||||
| Operating Loss | $ | (29.0) | $ | (27.9) | ||||||||||
Acquisition - amortization of intangible assets(1) | 9.1 | 10.7 | ||||||||||||
Equity compensation(2) | 9.5 | 11.9 | ||||||||||||
Real estate optimization(3) | 3.0 | 1.2 | ||||||||||||
Transformation initiatives(4) | — | 1.9 | ||||||||||||
Legal settlements(5) | — | (0.1) | ||||||||||||
Other adjustments(6) | 1.9 | 1.7 | ||||||||||||
| Adjusted Operating Loss | $ | (5.5) | $ | (0.6) | ||||||||||
| (1) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||||||||
| (2) | Consists of the non-cash equity-based compensation provided to Myriad Genetics employees and directors. | |||||||||||||
| (3) | Costs related to real estate initiatives. For the three months ended March 31, 2025, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South San Francisco, California, while maintaining our current laboratories in those locations and testing and set-up costs for equipment in our new facilities. For the three months ended March 31, 2024, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South Francisco, California, while maintaining our current laboratories in those locations, costs associated with the voluntary termination of a lease, testing and set-up costs for equipment in our new facilities, and impairment in connection with the ceased use of one of our facilities. | |||||||||||||
| (4) | Costs related to transformation initiatives including consulting and professional fees for the three months ended March 31, 2024. | |||||||||||||
| (5) | Costs related to one-time legal expenses, net of reimbursement for the three months ended March 31, 2024. | |||||||||||||
| (6) | Other one-time non-recurring expenses. For the three months ended March 31, 2025, consists primarily of severance related costs. For the three months ended March 31, 2024, primarily includes a gain recognized on acquisition, changes in the fair value of contingent consideration related to acquisitions from prior years, the reclassifications of cumulative translation adjustments to income upon liquidation of an investment in a foreign entity, and costs incurred in connection with executive personnel changes. | |||||||||||||
| Three Months Ended March 31, | ||||||||||||||
| 2025 | 2024 | |||||||||||||
Adjusted Net Loss (1) | ||||||||||||||
| Net Loss | $ | (0.1) | $ | (26.0) | ||||||||||
Acquisition - amortization of intangible assets(2) | 9.1 | 10.7 | ||||||||||||
Equity compensation(3) | 9.5 | 11.9 | ||||||||||||
Real estate optimization(4) | 3.0 | 1.2 | ||||||||||||
Transformation initiatives(5) | — | 1.9 | ||||||||||||
Legal settlements(6) | — | (0.1) | ||||||||||||
Other adjustments(7) | 1.9 | 0.2 | ||||||||||||
Uncertain tax benefit(8) | (28.7) | — | ||||||||||||
Tax adjustments(9) | 2.2 | (0.3) | ||||||||||||
| Adjusted Net Loss | $ | (3.1) | $ | (0.5) | ||||||||||
| Weighted average shares outstanding: | ||||||||||||||
| Basic and Diluted | 91.4 | 89.9 | ||||||||||||
| Adjusted Loss Per Share | ||||||||||||||
| Basic and Diluted | $ | (0.03) | $ | (0.01) | ||||||||||
| (1) | To determine Adjusted Earnings (Loss) Per Share, or adjusted EPS. | |||||||||||||
| (2) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||||||||
| (3) | Consists of the non-cash equity-based compensation provided to Myriad Genetics employees and directors. | |||||||||||||
| (4) | Costs related to real estate initiatives. For the three months ended March 31, 2025, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South San Francisco, California, while maintaining our current laboratories in those locations and testing and set-up costs for equipment in our new facilities. For the three months ended March 31, 2024, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South Francisco, California, while maintaining our current laboratories in those locations, costs associated with the voluntary termination of a lease, testing and set-up costs for equipment in our new facilities, and impairment in connection with the ceased use of one of our facilities. | |||||||||||||
| (5) | Costs related to transformation initiatives including consulting and professional fees for the three months ended March 31, 2024. | |||||||||||||
| (6) | Costs related to one-time legal expenses, net of reimbursement for the three months ended March 31, 2024. | |||||||||||||
| (7) | Other one-time non-recurring expenses. For the three months ended March 31, 2025, consists primarily of severance related costs. For the three months ended March 31, 2024, primarily includes a gain recognized on acquisition, changes in the fair value of contingent consideration related to acquisitions from prior years, the reclassifications of cumulative translation adjustments to income upon liquidation of an investment in a foreign entity, and costs incurred in connection with executive personnel changes. | |||||||||||||
| (8) | Consists of the release of unrecognized tax benefits and the recognition of valuation allowances for the three months ended March 31, 2025. The unrecognized tax benefits released were primarily related to tax years under Joint Committee on Taxation review, which upon conclusion of the review were remeasured or released. | |||||||||||||
| (9) | Tax expense or benefit due to non-GAAP adjustments, differences between stock compensation recorded for book purposes as compared to the allowable tax deductions, and valuation allowance recognized against federal and state deferred tax assets in the United States. As of March 31, 2025, a valuation allowance of $67.0 million was not recognized for non-GAAP purposes given our historical and forecasted positive earnings performance. As of March 31, 2024, a valuation allowance of $57.0 million was not recognized for non-GAAP purposes given the company's historical and forecasted positive earnings performance. | |||||||||||||
| Three Months Ended March 31, | ||||||||||||||
| 2025 | 2024 | |||||||||||||
| Adjusted EBITDA | ||||||||||||||
| Net Loss | $ | (0.1) | $ | (26.0) | ||||||||||
Acquisition - amortization of intangible assets(1) | 9.1 | 10.7 | ||||||||||||
Depreciation expense(2) | 5.1 | 4.5 | ||||||||||||
Equity compensation(3) | 9.5 | 11.9 | ||||||||||||
Real estate optimization(4) | 3.0 | 1.2 | ||||||||||||
Transformation initiatives(5) | — | 1.9 | ||||||||||||
Legal settlements (6) | — | (0.1) | ||||||||||||
Interest expense, net of interest income(7) | 0.5 | (0.1) | ||||||||||||
Other adjustments(8) | 2.1 | (0.1) | ||||||||||||
Uncertain tax benefits(9) | (28.7) | — | ||||||||||||
Income tax expense(10) | (0.6) | 0.1 | ||||||||||||
| Adjusted EBITDA | $ | (0.1) | $ | 4.0 | ||||||||||
| (1) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||||||||
| (2) | Depreciation expense excludes depreciation included in real estate optimization of $0.5 million for the three months ended March 31, 2024. No depreciation expense was included in real estate optimization for the three months ended March 31, 2025. | |||||||||||||
| (3) | Consists of the non-cash equity-based compensation provided to Myriad Genetics employees and directors. | |||||||||||||
| (4) | Costs related to real estate initiatives. For the three months ended March 31, 2025, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South San Francisco, California, while maintaining our current laboratories in those locations and testing and set-up costs for equipment in our new facilities. For the three months ended March 31, 2024, additional rent as a result of the build-out of our new laboratories in Salt Lake City, Utah and South Francisco, California, while maintaining our current laboratories in those locations, costs associated with the voluntary termination of a lease, testing and set-up costs for equipment in our new facilities, and impairment in connection with the ceased use of one of our facilities. | |||||||||||||
| (5) | Costs related to transformation initiatives including consulting and professional fees for the three months ended March 31, 2024. | |||||||||||||
| (6) | Costs related to one-time legal expenses, net of reimbursement for the three months ended March 31, 2024. | |||||||||||||
| (7) | Derived from interest expense and interest income from the Condensed Consolidated Statements of Operations. | |||||||||||||
| (8) | Other one-time non-recurring expenses. For purposes of adjusted EBITDA, this includes Other adjustments described in Adjusted Net Loss above as well as the amounts reported as Other income (expense) in the Condensed Consolidated Statement of Operations. | |||||||||||||
| (9) | Consists of the release of unrecognized tax benefits and the recognition of valuation allowances for the three months ended March 31, 2025. The unrecognized tax benefits released were primarily related to tax years under Joint Committee on Taxation review, which upon conclusion of the review were remeasured or released. | |||||||||||||
| (10) | Derived from income tax (benefit) from the Condensed Consolidated Statement of Operations, net of the adjustment for unrecognized tax benefits described above. | |||||||||||||
| Three Months Ended March 31, | ||||||||||||||
| 2025 | 2024 | |||||||||||||
| Adjusted free cash flow | ||||||||||||||
| Net cash used in operating activities | $ | (16.3) | $ | (18.6) | ||||||||||
Real estate optimization(1) | 4.0 | 6.2 | ||||||||||||
Transformation initiatives(2) | — | 1.9 | ||||||||||||
Other adjustments(3) | 1.9 | 1.2 | ||||||||||||
| Adjusted operating cash flow | $ | (10.4) | $ | (9.3) | ||||||||||
Capital expenditures(4) | (5.3) | (6.7) | ||||||||||||
Capitalization of internal-use software costs (4) | (3.0) | (1.9) | ||||||||||||
| Adjusted free cash flow | $ | (18.7) | $ | (17.9) | ||||||||||
| (1) | The cash flow effect of real estate optimizations, excluding non-cash items such as accelerated depreciation. | |||||||||||||
| (2) | Transformation initiatives includes the cash paid for those costs in the related periods. | |||||||||||||
| (3) | The cash flow effect of severance and executive personnel changes in the related periods. | |||||||||||||
| (4) | Derived from the Condensed Consolidated Statements of Cash Flows. | |||||||||||||