Position in APLS
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$0
+$0 QoQ
Shares Held
6,844,990
+48.4% QoQ
Ownership
5.35%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority
Sole 7%
Shared 0%
None 93%
Common Shares in APLS Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026STATE STREET CORP holds $36,552,510,511 across 411 Biotechnology names.
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
11,871,459 | $5,896,909,829 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
4,834,688 | $3,014,621,355 | |
| 3 | INCY |
Incyte Corp
|
9,722,336 | $1,102,124,008 | |
| 4 | MRNA |
Moderna, Inc.
|
15,726,193 | $1,101,305,295 | |
| 5 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
3,555,689 | $1,070,369,059 | |
| 6 | RVMD |
Revolution Medicines, Inc.
|
4,897,051 | $917,119,711 | |
| 7 | RPRX |
Royalty Pharma plc
|
12,338,229 | $691,804,500 | |
| 8 | INSM |
INSMED Inc
|
6,052,174 | $645,282,791 |
All Filings in APLS
Export CSV
26 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $275,375,597 | 6,845,031 | Shares | Sole | 2026-05-12 | |
| 2026-03-31 | — | 6,844,990 | Shares | Defined | 2026-05-15 | |
| 2025-12-31 | — | 4,613,446 | Shares | Defined | 2026-02-13 | |
| 2025-09-30 | — | 4,037,644 | Shares | Defined | 2025-11-14 | |
| 2025-06-30 | — | 3,562,721 | Shares | Defined | 2025-08-14 | |
| 2025-03-31 | — | 3,941,405 | Shares | Defined | 2025-05-15 | |
| 2024-12-31 | — | 4,525,155 | Shares | Defined | 2025-02-14 | |
| 2024-09-30 | — | 4,040,861 | Shares | Defined | 2024-11-14 | |
| 2024-06-30 | — | 4,146,694 | Shares | Defined | 2024-08-14 | |
| 2024-03-31 | — | 2,909,528 | Shares | Defined | 2024-05-15 | |
| 2023-12-31 | — | 2,915,422 | Shares | Defined | 2024-02-14 | |
| 2023-09-30 | — | 3,238,114 | Shares | Defined | 2023-11-14 | |
| 2023-06-30 | — | 2,283,085 | Shares | Defined | 2023-08-14 | |
| 2023-03-31 | — | 2,979,862 | Shares | Defined | 2023-05-15 | |
| 2022-12-31 | — | 3,471,914 | Shares | Defined | 2023-05-15 | |
| 2022-09-30 | — | 2,957,273 | Shares | Defined | 2022-11-15 | |
| 2022-06-30 | — | 3,496,925 | Shares | Defined | 2022-08-15 | |
| 2022-03-31 | — | 2,906,456 | Shares | Defined | 2022-05-16 | |
| 2021-12-31 | — | 2,719,368 | Shares | Defined | 2022-02-14 | |
| 2021-09-30 | — | 2,826,195 | Shares | Defined | 2021-11-15 | |
| 2021-06-30 | — | 1,946,968 | Shares | Defined | 2021-08-16 | |
| 2021-03-31 | — | 2,198,573 | Shares | Defined | 2021-07-09 | |
| 2020-12-31 | — | 2,430,753 | Shares | Defined | 2021-02-16 | |
| 2020-09-30 | — | 2,864,159 | Shares | Defined | 2020-11-10 | |
| 2020-06-30 | — | 2,946,814 | Shares | Defined | 2020-08-14 | |
| 2020-03-31 | — | 2,498,764 | Shares | Defined | 2020-06-19 | |
| No filing history on record for this holder in this stock. | ||||||