JANE STREET GROUP, LLC

Position in AVXL — Anavex Life Sciences Corp.

CIK 1595888 NEW YORK, NY

Back to AVXL Full portfolio

Position in AVXL

as of Mar 31, 2026 · filed May 12, 2026 Compact

Position Value

$2,225,758

-$511,721 QoQ

Shares Held

725,003

-5.7% QoQ

Ownership

0.782%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Sep 2020

23 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in AVXL Over Time

Shares Held

Position Value (USD)

Derivatives in AVXL

reported options exposure · as of Dec 31, 2025

CallValue

$236,740

CallShares

66,500

PutValue

$87,932

PutShares

24,700

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

JANE STREET GROUP, LLC holds $1,255,284,514 across 317 Biotechnology names. AVXL ranks #79 (0.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	BBIO	BridgeBio Pharma, Inc.	1,757,672	$130,524,721
2	RPRX	Royalty Pharma plc	2,400,382	$115,146,324
3	TGTX	Tg Therapeutics, Inc.	2,041,669	$67,824,242
4	VRTX	Vertex Pharmaceuticals Inc / Ma	122,946	$54,900,305
5	HALO	Halozyme Therapeutics, Inc.	831,707	$53,753,223
6	EXEL	Exelixis, Inc.	1,087,030	$46,622,715
7	JAZZ	Jazz Pharmaceuticals plc	223,615	$42,274,415
8	BNTX	BioNTech SE	336,757	$29,930,962

All Filings in AVXL

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39 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$2,225,758	725,003	+2835.2%	Shares	Defined	2026-05-12
2025-12-31	$87,932	24,700	-96.8%	Put	Defined	2026-02-12
2025-12-31	$2,737,479	768,955	+1056.3%	Shares	Defined	2026-02-12
2025-12-31	$236,740	66,500	-69.5%	Call	Defined	2026-02-12
2025-09-30	$1,942,130	218,217	+143.0%	Shares	Defined	2025-11-14
2025-09-30	$799,220	89,800	+23.7%	Call	Defined	2025-11-14
2025-06-30	$669,372	72,600	+310.6%	Call	Defined	2025-08-14
2025-06-30	$163,018	17,681	-80.8%	Shares	Defined	2025-08-14
2025-03-31	$791,934	92,300	+134.3%	Call	Defined	2025-05-19
2024-12-31	$423,156	39,400	-62.4%	Call	Defined	2025-02-14
2024-12-31	$1,124,445	104,697	+67.7%	Shares	Defined	2025-02-14
2024-09-30	$354,516	62,415	-65.7%	Shares	Defined	2024-11-15
2024-06-30	$767,811	181,946	+305.2%	Shares	Defined	2024-08-15
2024-03-31	$228,540	44,900	-60.0%	Shares	Defined	2024-05-16
2023-12-31	$1,045,605	112,310	+36.5%	Shares	Defined	2024-02-15
2023-09-30	$538,744	82,251	-81.1%	Shares	Defined	2023-11-15
2023-06-30	$3,530,793	434,292	+1962.1%	Shares	Defined	2023-08-14
2023-03-31	$180,492	21,061	+53.0%	Shares	Defined	2023-05-16
2022-12-31	$127,491	13,768	-37.8%	Shares	Defined	2023-02-15
2022-09-30	$228,278	22,120	+16.4%	Shares	Defined	2022-11-15
2022-06-30	$190,158	18,997	-79.3%	Shares	Defined	2022-08-16
2022-03-31	$1,130,094	91,803	-25.9%	Shares	Defined	2022-05-17
2022-03-31	$1,525,209	123,900	-47.9%	Put	Defined	2022-05-17
2022-03-31	$2,926,087	237,700	+68.8%	Call	Defined	2022-05-17
2021-12-31	$2,441,472	140,800	-7.5%	Put	Defined	2022-02-15
2021-12-31	$2,638,038	152,136	-25.6%	Shares	Defined	2022-02-15
2021-12-31	$3,546,030	204,500	-2.1%	Call	Defined	2022-02-15
2021-09-30	$3,747,960	208,800	+2.3%	Call	Defined	2021-11-16
2021-09-30	$3,663,397	204,089	-10.8%	Shares	Defined	2021-11-16
2021-09-30	$4,106,960	228,800	-29.7%	Put	Defined	2021-11-16
2021-06-30	$7,436,358	325,300	-11.0%	Put	Defined	2021-08-16
2021-06-30	$8,357,616	365,600	+78.0%	Call	Defined	2021-08-16
2021-06-30	$4,696,586	205,450	+439.2%	Shares	Defined	2021-08-16
2021-03-31	$569,595	38,100	-21.9%	Put	Defined	2021-05-18
2021-03-31	$729,560	48,800	-39.4%	Call	Defined	2021-05-18
2021-03-31	$1,203,608	80,509	+96.8%	Shares	Defined	2021-05-18
2020-12-31	$220,860	40,900	+292.1%	Call	Defined	2021-02-17
2020-12-31	$56,326	10,431	-80.7%	Shares	Defined	2021-02-17
2020-09-30	$245,895	54,043	—	Shares	Defined	2020-11-17
No filing history on record for this holder in this stock.