6-K

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON D.C. 20549

FORM 6-K

Report ofForeign Private Issuer

Pursuant to Rule 13a-16 or15d-16 of

the Securities Exchange Act of 1934

June 14, 2022

CHINASOUTHERN AIRLINES COMPANY LIMITED

68 Qi Xin Road

Guangzhou, 510403

People’s Republic of China

(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

Form 20-F  ☒             Form 40-F  ☐

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):   ☐

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):   ☐

Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

Yes  ☐    No  ☒

If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b):   N/A

China Southern Airlines Company Limited (the “Company”) published the following announcement on June 13, 2022 on the Hong Kong Stock Exchange’s website at:

https://www1.hkexnews.hk/listedco/listconews/sehk/2022/0613/2022061300868.pdf, in relation to the proposed amendment to the articles of association.

The announcement in English is included as an exhibit to this Form 6-K.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: June 14, 2022

EX-99.1

Exhibit 99.1

Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement, make norepresentation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement.

(a joint stock limited company incorporated in the People’s Republic of China with limited liability)

(Stock Code: 1055)

ANNOUNCEMENT

PROPOSEDAMENDMENT TO THE ARTICLES OF

ASSOCIATION

The board (the “Board”) of directors of China Southern Airlines Company Limited (the “Company”) announces that the ninth session of the Board has agreed by signing to approve, among others, the resolution in relation to the proposed amendment (the “Proposed Amendment”) to the Articles of Association of the Company (the “Articles ofAssociation”) on 13 June 2022.

To meet the needs of business operation, the Company proposed to expand the scope of business of the Company. Accordingly, the Articles of Association has to be amended to reflect such change to the scope of business.

1

The details of the Proposed Amendment are as follows:

Except for the clause as stated above, other clauses in the Articles of Association remain unchanged.

The Proposed Amendment is subject to the approval of the shareholders of the Company by way of a special resolution at the annual general meeting (the “AGM”) to be held on Thursday, 30 June 2022, and the obtaining of any approval, endorsement or registration (as applicable) from or with the relevant government authorities in the PRC.

2

A circular containing, inter alia, further details of the Proposed Amendment together with a supplemental notice of the AGM will be despatched to the shareholders of the Company as soon as practicable.

Guangzhou, the People’s Republic of China

13 June 2022

As at the date of this announcement, thedirectors include Ma Xu Lun and Han Wen Sheng as executive directors; and Liu Chang Le, Gu Hui Zhong, Guo Wei and Yan Andrew Y as independent non-executive directors.

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