TWO SIGMA INVESTMENTS, LP

CIK

1179392

City

NEW YORK

State / Country

Stock

CNC — Centene Corp

Top Portfolio Positions

3,307 positions · $112,062,244,503 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio
NVDA	Nvidia Corp Technology	12,053,545	$2,102,138,248	1.88%
AAPL	Apple Inc. Technology	6,085,143	$1,544,348,441	1.38%
GOOGL	Alphabet Inc. Communication Services	4,810,528	$1,383,315,431	1.23%
AMZN	Amazon Com Inc Consumer Cyclical	6,454,567	$1,344,292,669	1.20%
TSLA	Tesla, Inc. Consumer Cyclical	3,116,099	$1,158,409,803	1.03%
JPM	Jpmorgan Chase & Co Financial Services	3,523,588	$1,036,498,646	0.92%
PLTR	Palantir Technologies Inc. Technology	6,809,802	$996,137,836	0.89%
COST	Costco Wholesale Corp /New Consumer Defensive	891,093	$887,911,797	0.79%
TJX	Tjx Companies Inc /De/ Consumer Cyclical	5,277,968	$842,891,489	0.75%
MA	Mastercard Inc Financial Services	1,682,998	$840,926,780	0.75%

25 quarters · across all stocks

25 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$220,796,792	6,743,946	+182.1%	Shares	Sole	2026-05-15
2025-12-31	$98,386,358	2,390,920	-32.8%	Shares	Sole	2026-02-17
2025-09-30	$126,872,763	3,555,851	+12.8%	Shares	Sole	2025-11-14
2025-06-30	$171,102,990	3,152,229	-11.4%	Shares	Sole	2025-08-14
2025-03-31	$215,905,158	3,556,336	+58.4%	Shares	Sole	2025-05-15
2024-12-31	$136,033,056	2,245,511	+1788.1%	Shares	Sole	2025-02-14
2024-09-30	$8,952,975	118,929	+377.5%	Shares	Sole	2024-11-14
2024-03-31	$1,954,544	24,905	-96.3%	Shares	Sole	2024-05-15
2023-12-31	$49,591,797	668,263	-18.5%	Shares	Sole	2024-02-14
2023-09-30	$56,498,544	820,246	+22.0%	Shares	Sole	2023-11-14
2023-06-30	$45,357,764	672,465	-72.8%	Shares	Sole	2023-08-14
2023-03-31	$156,374,207	2,473,884	+510.8%	Shares	Sole	2023-05-15
2022-12-31	$33,214,542	405,006	+6539.4%	Shares	Sole	2023-02-14
2021-12-31	$502,640	6,100	-78.6%	Put	Sole	2022-02-14
2021-09-30	$1,775,835	28,500	+68.6%	Put	Sole	2021-11-15
2021-09-30	$1,053,039	16,900	+74.2%	Call	Sole	2021-11-15
2021-06-30	$707,421	9,700	+11.5%	Call	Sole	2021-08-16
2021-06-30	$634,491	8,700	-40.8%	Put	Sole	2021-08-16
2020-12-31	$882,441	14,700	+33.6%	Put	Sole	2021-02-16
2020-12-31	$660,330	11,000	+175.0%	Call	Sole	2021-02-16
2020-09-30	$233,320	4,000	-81.8%	Call	Sole	2020-11-16
2020-06-30	$1,398,100	22,000	-91.4%	Put	Sole	2020-08-14
2020-06-30	$16,284,369	256,245	+1679.5%	Shares	Sole	2020-08-14
2020-06-30	$915,120	14,400	+278.9%	Call	Sole	2020-08-14
2020-03-31	$225,758	3,800	—	Put	Sole	2020-05-15
No 13F history on record for this holder in this stock.