Opaleye Management Inc.

CIK
0001595855
City
Boston
State / Country
MA

Top Portfolio Positions

46 positions · $726,537,966 total · as of Dec 31, 2025
Ticker Company Shares Value (USD) % of Portfolio
HROW
Harrow, Inc.
Healthcare
3,905,000 $191,345,000 26.34%
LQDA
Liquidia Corp
Healthcare
2,435,000 $83,983,150 11.56%
ETON
Eton Pharmaceuticals, Inc.
Healthcare
2,860,000 $48,362,600 6.66%
RYTM
Rhythm Pharmaceuticals, Inc.
Healthcare
330,000 $35,323,200 4.86%
APGE
Apogee Therapeutics, Inc.
Healthcare
388,257 $29,305,638 4.03%
SNWV
SANUWAVE Health, Inc.
Healthcare
981,267 $29,281,007 4.03%
STOK
Stoke Therapeutics, Inc.
Healthcare
695,000 $22,059,300 3.04%
OCUL
Ocular Therapeutix, Inc
Healthcare
1,595,000 $19,363,300 2.67%
SLGL
Sol-Gel Technologies Ltd.
Healthcare
453,739 $19,120,561 2.63%
CGON
CG Oncology, Inc.
Healthcare
410,000 $17,023,200 2.34%

Portfolio Trend

24 quarters · across all stocks

Holdings in DERM

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Shares Held

Position Value (USD)

7 of 7 shown
Report Date Value (USD) Shares
2025-12-31 $7,517,250 975,000
2025-09-30 $6,913,975 971,064
2025-06-30 $682,100 95,000
2025-03-31 $409,005 69,323
2022-09-30 $637,860 259,293
2022-06-30 $919,041 245,733
2022-03-31 $323,610 67,000