MANUFACTURERS LIFE INSURANCE COMPANY, THE

Insurance

CIK

928047

City

TORONTO

State / Country

Stock

DNLI — Denali Therapeutics Inc.

Top Portfolio Positions

2,628 positions · $102,757,019,220 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio
MSFT	Microsoft Corp Technology	11,164,853	$4,132,893,635	4.02%
NVDA	Nvidia Corp Technology	19,278,112	$3,362,102,732	3.27%
AMZN	Amazon Com Inc Consumer Cyclical	15,863,698	$3,303,932,382	3.22%
GOOGL	Alphabet Inc. Communication Services	10,423,352	$2,997,339,101	2.92%
AAPL	Apple Inc. Technology	11,401,668	$2,893,629,321	2.82%
RY	Royal Bank Of Canada Financial Services	12,130,512	$1,962,474,231	1.91%
META	Meta Platforms, Inc. Communication Services	3,017,628	$1,726,475,507	1.68%
AVGO	Broadcom Inc. Technology	5,310,766	$1,643,735,184	1.60%
TD	Toronto Dominion Bank Financial Services	16,927,399	$1,579,495,600	1.54%
LLY	ELI LILLY & Co Healthcare	1,447,173	$1,331,066,310	1.30%

52 quarters · across all stocks

Compact Export CSV

25 of 25 shown

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$2,408,486	125,442	-31.9%	Shares	Defined	2026-05-15
2025-12-31	$3,041,769	184,238	-10.5%	Shares	Defined	2026-02-13
2025-09-30	$2,988,869	205,845	-34.7%	Shares	Defined	2025-11-14
2025-06-30	$4,408,276	315,102	+22.1%	Shares	Defined	2025-08-14
2025-03-31	$3,509,304	258,132	+23.8%	Shares	Defined	2025-05-15
2024-12-31	$4,249,657	208,521	+0.8%	Shares	Defined	2025-02-14
2024-09-30	$6,024,637	206,819	+20.0%	Shares	Defined	2024-11-13
2024-06-30	$4,000,364	172,281	+15.5%	Shares	Defined	2024-08-14
2024-03-31	$3,059,860	149,116	+47.3%	Shares	Defined	2024-05-14
2023-12-31	$2,172,245	101,223	-10.7%	Shares	Defined	2024-02-13
2023-09-30	$2,339,400	113,398	-4.7%	Shares	Defined	2023-11-15
2023-06-30	$3,510,184	118,949	+3.3%	Shares	Defined	2023-08-11
2023-03-31	$2,653,816	115,183	+2.8%	Shares	Defined	2023-05-15
2022-12-31	$3,116,360	112,059	+1.6%	Shares	Defined	2023-08-11
2022-09-30	$3,383,787	110,257	-8.3%	Shares	Defined	2023-08-11
2022-06-30	$3,540,046	120,287	+1.9%	Shares	Defined	2023-08-11
2022-03-31	$3,798,794	118,085	+154.0%	Shares	Defined	2023-08-11
2021-12-31	$2,073,721	46,496	-0.9%	Shares	Defined	2022-02-16
2021-09-30	$2,367,870	46,935	-8.6%	Shares	Defined	2021-11-12
2021-06-30	$4,026,560	51,333	+42.4%	Shares	Defined	2021-08-12
2021-03-31	$2,058,226	36,046	-5.8%	Shares	Defined	2021-05-03
2020-12-31	$3,204,992	38,264	+3.0%	Shares	Defined	2021-02-12
2020-09-30	$1,330,977	37,147	-2.8%	Shares	Defined	2020-11-09
2020-06-30	$923,627	38,198	+14.1%	Shares	Defined	2020-08-10
2020-03-31	$586,077	33,471	—	Shares	Defined	2020-05-15
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