Position in ESPR
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$0
+$0 QoQ
Shares Held
7,126,739
-24.7% QoQ
Ownership
2.77%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Jun 2020
23 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in ESPR Over Time
Shares Held
Position Value (USD)
Position in Drug Manufacturers - Specialty & Generic
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $775,744,366 across 48 Drug Manufacturers - Specialty & Generic names. ESPR ranks #48 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | NBIX |
Neurocrine Biosciences Inc
|
2,076,260 | $349,932,860 | |
| 2 | BCRX |
Biocryst Pharmaceuticals Inc
|
6,775,349 | $67,753,490 | |
| 3 | SUPN |
Supernus Pharmaceuticals, Inc.
|
1,184,378 | $55,085,420 | |
| 4 | ALKS |
Alkermes plc.
|
1,038,311 | $54,407,496 | |
| 5 | KNSA |
Kiniksa Pharmaceuticals International, plc
|
561,480 | $35,906,646 | |
| 6 | ZTS |
Zoetis Inc.
|
386,428 | $27,768,716 | |
| 7 | LQDA |
Liquidia Corp
|
266,829 | $21,274,276 | |
| 8 | IRWD |
Ironwood Pharmaceuticals Inc
|
4,556,089 | $19,181,134 |
All Filings in ESPR
Export CSV
23 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | — | 7,126,739 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | — | 9,458,779 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | — | 4,742,082 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | — | 2,238,618 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | — | 1,827,994 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | — | 2,731,287 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | — | 3,540,361 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | — | 3,625,059 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | — | 4,074,961 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | — | 3,975,560 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | — | 2,334,410 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | — | 1,457,935 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | — | 1,176,848 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | — | 1,062,898 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | — | 1,537,664 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | — | 1,068,438 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | — | 382,403 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | — | 139,899 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | — | 342,647 | Shares | Sole | 2022-02-14 | |
| 2021-03-31 | — | 48,670 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | — | 51,964 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | — | 18,930 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | — | 28,132 | Shares | Sole | 2020-08-14 | |
| No filing history on record for this holder in this stock. | ||||||