8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

________________

FORM 8-K

________________

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of report (Date of earliest event reported): January 18, 2022

________________

HANCOCK WHITNEY CORPORATION
(Exact Name of Registrant as Specified in Charter)<br>________________
Mississippi			64-0693170
(State or Other Jurisdiction<br>of Incorporation)			(IRS Employer<br><br><br>Identification No.)
Hancock Whitney Plaza<br>2510 14th Street<br>Gulfport, Mississippi<br>(Address of Principal Executive Offices)		39501<br><br><br>(Zip Code)
Registrant’s telephone number, including area code: (228) 868-4000
Securities registered pursuant to Section 12(b) of the Act:
Title of Each Class<br>COMMON STOCK, 3.33 PAR VALUE<br>6.25% SUBORDINATED NOTES	Trading Symbol<br><br><br>HWC<br><br><br>HWCPZ		Name of Exchange on Which Registered<br><br><br>The NASDAQ Stock Market, LLC<br><br><br>The NASDAQ Stock Market, LLC
__________________

All values are in US Dollars.

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐	Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
☐	Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
☐	Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
☐	Pre-commencement communication pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act (17 CFR 230.405) or Rule 12b-2 of the Exchange Act (17 CFR 240.12b-2)

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02Results of Operations and Financial Condition.

On January 18, 2022, Hancock Whitney Corporation (the “Company”) announced financial results for its fourth quarter ended December 31, 2021. A copy of this press release and the accompanying financial statements are attached hereto as Exhibit 99.1 and is incorporated by reference into this Item 2.02. The press release is available on the Company’s website.

The information provided in Item 2.02 of this report, including Exhibit 99.1, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended.

Item 7.01Regulation FD Disclosure.

On January 18, 2022 at 4:00 p.m. (Central Time), the Company intends to hold an investor call and webcast to discuss financial results for the quarter ended December 31, 2021, including the press release.  Additional presentation materials relating to such call are furnished hereto as Exhibit 99.2 and are, along with the press release and financial statements, incorporated herein by reference. All information in the press release and presentation materials speak as of the date thereof and the Company does not assume any obligation to update said information in the future. In addition, the Company disclaims any inferences regarding the materiality of such information which otherwise may arise as a result of it furnishing such information under Item 2.02 or Item 7.01 of this Form 8-K.

In accordance with the General Instruction B.2 of Form 8-K, the information presented herein pursuant to Item 2.02, “Results of Operations,” and Item 7.01, “Regulation FD,” shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), nor shall the information be deemed incorporated by reference in any filing under the Exchange Act or the Securities Act of 1933, as amended, except as expressly set forth by specific reference in such filing.

Item 9.01Financial Statements and Exhibits.

(d)  Exhibits.

Exhibit<br><br><br>Number	Description
99.1	Press Release dated January 18, 2022 for Quarter Ended December 31, 2021.
99.2	Presentation Slides dated January 18, 2022 (furnished with the Commission as part of this Form 8-K).
104	Cover Page Interactive Data File (embedded within the inline XBRL document)

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

		HANCOCK WHITNEY CORPORATION
January 18, 2022	By:	/s/ Michael M. Achary
		Michael M. Achary
		Chief Financial Officer

hwc-ex991_7.htm

Exhibit 99.1

<br><br><br>FOR IMMEDIATE RELEASE<br><br><br>January 18, 2022

For more information

Trisha Voltz Carlson, EVP, Investor Relations Manager

504.299.5208 or trisha.carlson@hancockwhitney.com

Hancock Whitney reports fourth quarter 2021 EPS of $1.55

A Strong Finish to a Record Year; 2021 EPS totaled $5.22

GULFPORT, Miss. (January 18, 2022) — Hancock Whitney Corporation (Nasdaq: HWC) today announced its financial results for the fourth quarter of 2021. Net income for the fourth quarter of 2021 totaled $137.7 million, or $1.55 per diluted common share (EPS), compared to $129.6 million, or $1.46 per diluted common share, in the third quarter of 2021. The fourth quarter of 2021 included ($4.9) million, or ($0.04) per share after-tax, of net nonoperating income items, mostly from storm-related insurance proceeds. The third quarter of 2021 included ($1.4) million, or ($0.01) per share after-tax, of net nonoperating income items, related to Hurricane Ida expenses offset by severance reversal and a gain from the sale of the remaining Hancock Horizon Funds. Excluding the impact of these nonoperating items in both quarters, EPS would be up $0.06 linked-quarter. The company reported net income for the fourth quarter of 2020 of $103.6 million, or $1.17 per diluted common share. There were no nonoperating items in the fourth quarter of 2020.

Fourth Quarter 2021 Highlights

•	Pre-provision net revenue (PPNR) totaled $134.2 million, down slightly, linked-quarter
•	Core loan growth of $652.5 million, more than offset the impact of $404.3 million in PPP loan forgiveness leading to an overall increase in total loans of $248.3 million linked-quarter
---	---
•	Deposits increased $1.3 billion as noninterest-bearing demand deposits increased $739.4 million and interest-bearing accounts increased $518.3 million
---	---
•	$29.1 million reserve release and $0.7 million in net charge-offs led to a negative provision for credit losses of $28.4 million
---	---
•	ACL coverage remained strong at 1.76% (1.80% excluding PPP loans)
---	---
•	Both nonperforming loans and criticized commercial loans declined 6% and 2%, respectively, linked-quarter
---	---
•	The continued impact of excess liquidity, driven mainly by PPP loan forgiveness and Hurricane Ida related deposits, led to a 14 bps compression in reported NIM
---	---
•	TCE ratio 7.71%, down 14 bps, impacted by OCI and excess liquidity
---	---

“Fourth quarter’s results were a strong finish to a record year,” said John M. Hairston, President & CEO. “Our company grew to over $36 billion in total assets, as both loan and deposit growth exceeded expectations. Annual earnings per share were $5.22, compared to a loss in 2020, while operating pre-provision, net revenue (PPNR) totaled $538 million, an increase of $46.5 million, or 9%. The work we started pre-pandemic, coupled with the de-risking efforts in early 2020, have put us on a path to achieving updated corporate strategic objectives (CSOs), including the previously announced path to a 55% efficiency ratio. Expense management efforts are evident as we surpassed our target for the fourth quarter of 2021, while revenue initiatives are underway. Today our credit metrics are among the best in class, and our capital remains solid despite the impact of excess liquidity on our TCE ratio.

We are looking forward to carrying the momentum from the year-end finish to a brighter 2022, not only for our company, but for our clients, associates and communities, as we hopefully begin to emerge from today’s ongoing pandemic environment.”

Loans

Loans totaled $21.1 billion at December 31, 2021, up $248.3 million, or 1%, linked-quarter. Core loans increased $652.5 million from September 30, 2021, more than offsetting the impact of $404.3 million in PPP loan forgiveness. Growth was reflected in markets across the footprint and in specialty lines. Management expects core loans to grow by 6-8% in 2022, while quarterly results will reflect normal seasonality.

Average loans totaled $20.8 billion for the fourth quarter of 2021, down $171.0 million, or 1%, linked-quarter. ~~~~

Deposits

Total deposits at December 31, 2021 were $30.5 billion, up $1.3 billion, or 4%, from September 30, 2021. Seasonality, excess liquidity related to stimulus and other pandemic-related client funds, and hurricane related recovery proceeds contributed to the fourth quarter of 2021’s elevated level of deposits.

DDAs totaled $14.4 billion at December 31, 2021, up $739.4 million, or 5%, from September 30, 2021 and comprised 47% of total period-end deposits. Interest-bearing transaction and savings deposits totaled $11.6 billion at the end of the fourth quarter of 2021, an increase of $358.0 million, or 3%, linked-quarter. Compared to September 30, 2021, time deposits of $1.1 billion were down $78.9 million, or 7%. Interest-bearing public fund deposits increased $239.2 million, or 8%, linked-quarter, ending December 31, 2021 at $3.3 billion.

Management expects 2022 deposit levels to remain flat to slightly down.

Average deposits for the fourth quarter of 2021 were $29.8 billion, up $513.4 million, or 2%, linked-quarter.

Asset Quality

The total allowance for credit losses (ACL) was $371.4 million at December 31, 2021, down $29.1 million from September 30, 2021. During the fourth quarter of 2021, the company recorded a negative provision for credit losses of $28.4 million, compared to a negative provision of $27.0 million in the third quarter of 2021. Net charge-offs totaled $0.7 million in the fourth quarter of 2021, or 0.01% of average total loans on an annualized basis, down from $1.8 million, or 0.03% of average total loans in the third quarter of 2021. The ratio of ACL to period-end loans was 1.76% (1.80% excluding PPP loans) at December 31, 2021, compared to 1.92% (2.00% excluding PPP loans) at September 30, 2021.

The company’s overall asset quality metrics continued to improve with commercial criticized and total nonperforming loans down 2% and 6%, respectively, linked-quarter. Nonperforming assets (NPAs) totaled $66.8 million at December 31, 2021, down $5.0 million, or 7%, from September 30, 2021. During the fourth quarter of 2021, total nonperforming loans decreased $4.1 million, or 6%, while ORE and foreclosed assets were down $0.9 million, or 11% linked-quarter. Nonperforming assets as a percent of total loans, ORE and other foreclosed assets was 0.32% at December 31, 2021, down 2 bps from September 30, 2021.

Net Interest Income and Net Interest Margin (NIM)

Net interest income (TE) for the fourth quarter of 2021 was $231.9 million, a decrease of $5.5 million, or 2%, from the third quarter of 2021.

The net interest margin (NIM) was 2.80% in the fourth quarter of 2021, a decline of 14 bps linked-quarter. Factors driving the NIM compression are mainly related to the impact of additional excess liquidity noted earlier (-10 bps), change in earning asset yield (-4 bps) and forgiveness of over $400 million in PPP loans (-2 bps), partly offset by lower deposit costs (+1 bp) and other (+1 bp).

Average earning assets were $32.9 billion for the fourth quarter of 2021, up $816.3 million, or 3%, from the third quarter of 2021.

Management expects NIM to remain flat to slightly down through mid-year 2022, and then begin to expand.

Noninterest Income

Noninterest income totaled $89.6 million for the fourth quarter of 2021, down $3.7 million, or 4%, from the third quarter of 2021. Included in noninterest income was a $3.6 million gain from storm-related insurance proceeds (nonoperating item). In the third quarter of 2021, noninterest income included a $4.6 million gain from the sale of the remaining Hancock Horizon Funds. Adjusting for these items, noninterest income for the fourth quarter of 2021 totaled $86.0 million, down $2.8 million, or 3%, linked-quarter.

Service charges on deposits were up $0.2 million, or 1%, from the third quarter of 2021. Bankcard and ATM fees were up $0.8 million, or 4%, from the third quarter of 2021, driven by seasonality and improved economic activity and consumer-spending patterns.

Investment and annuity income and insurance fees were up $0.4 million, or 5%, linked-quarter. Trust fees were down $0.5 million, or 3% linked-quarter.

Fees from secondary mortgage operations totaled $5.5 million for the fourth quarter of 2021, down $1.5 million, or 22%, linked-quarter, as we are currently seeing a slowdown in activity compared to 2020’s refinance “boom”.

Other noninterest income totaled $19.1 million, down $3.1 million, or 14%, from the third quarter of 2021. The decrease is due to a lower level of specialty income.

Noninterest Expense & Taxes

Noninterest expense totaled $182.5 million, down $12.2 million, or 6% linked-quarter. Included in the total was ($1.3) million of net nonoperating expenses related primarily to partial reversals of accruals for Hurricane Ida expense and closed branch writedowns. In the third quarter of 2021, noninterest expense included $3.2 million, related primarily to Hurricane Ida, partly offset by a reversal of severance. Excluding these items, operating expense totaled $183.8 in the fourth quarter of 2021, down $7.7 million, or 4%, linked-quarter.

Personnel expense (operating) totaled $107.2 million in the fourth quarter of 2021, down $6.7 million, or 6%, linked-quarter. The decrease is mainly related to savings associated with efficiency initiatives noted last quarter.

Occupancy and equipment expense totaled $16.0 million in the fourth quarter of 2021, down $0.8 million, or 5%, from the third quarter of 2021. Amortization of intangibles totaled $3.9 million for the fourth quarter of 2021, down $0.2 million, or 4%, linked-quarter.

ORE and other foreclosed assets expense totaled $0.2 million in the fourth quarter of 2021, compared to gains exceeding expenses by $0.4 million in the third quarter of 2021.

Other operating expense totaled $56.4 million in the fourth quarter of 2021, virtually flat linked-quarter.

The effective income tax rate for fourth quarter 2021 was 16.4%. The lower than normal rate was related to the company revising its tax elections in anticipation of potential tax reform to a higher statutory tax rate. The company expects the tax rate to return to a normal quarterly range of 19-20% in 2022, absent any changes in tax laws. The effective income tax rate continues to be less than the statutory rate due primarily to tax-exempt income and tax credits.

Capital

Common stockholders’ equity at December 31, 2021 totaled $3.7 billion, up $40.6 million, or 1%, from September 30, 2021. The tangible common equity (TCE) ratio was 7.71%, down 14 bps from September 30, 2021, mainly the result of excess liquidity and a year-end fair value adjustment in OCI. The company’s CET1 ratio is estimated to be 11.16% at December 31, 2021, virtually flat linked-quarter. During the fourth quarter of 2021, the company repurchased 393,527 shares of its common stock at an average price of $48.98 per share. This stock repurchase is part of the Board authorization to repurchase up to 4,338,000 shares of the company’s common stock, set to expire December 31, 2022. To-date the company has repurchased 449,876 shares under this authorization.

Conference Call and Slide Presentation

Management will host a conference call for analysts and investors at 4:00 p.m. Central Time on Tuesday, January 18, 2022 to review the results. A live listen-only webcast of the call will be available under the Investor Relations section of Hancock Whitney’s website at investors.hancockwhitney.com. A link to the release with additional financial tables, and a link to a slide presentation related to fourth quarter results are also posted as part of the webcast link. To participate in the Q&A portion of the call, dial 844-200-6205 or 646-904-5544, access code 925066.

An audio archive of the conference call will be available under the Investor Relations section of our website. A replay of the call will also be available through January 25, 2022 by dialing 866-813-9403 or 929-458-6194, access code 899285.

About Hancock Whitney

Since the late 1800s, Hancock Whitney has embodied core values of Honor & Integrity, Strength & Stability, Commitment to Service, Teamwork, and Personal Responsibility. Hancock Whitney offices and financial centers in Mississippi, Alabama, Florida, Louisiana, and Texas offer comprehensive financial products and services, including traditional and online banking; commercial and small business banking; private banking; trust and investment services; healthcare banking; certain insurance services; and mortgage services. The company also operates a loan production office in Nashville, Tennessee. BauerFinancial, Inc., the nation’s leading independent bank rating and analysis firm, consistently recommends Hancock Whitney as one of America’s most financially sound banks. More information is available at www.hancockwhitney.com.

Non-GAAP Financial Measures

This news release includes non-GAAP financial measures to describe Hancock Whitney’s performance. These non-GAAP financial measures should not be considered alternatives to GAAP-basis financial statements and other bank holding companies may define or calculate these non-GAAP measures or similar measures differently. The reconciliations of those measures to GAAP measures are provided either in the financial tables or in Appendix A thereto.

Consistent with the provisions of subpart 229.1400 of the Securities and Exchange Commission’s Regulation S-K, “Disclosures by Bank and Savings and Loan Registrants,” the company presents net interest income, net interest margin and efficiency ratios on a fully taxable equivalent (“TE”) basis. The TE basis adjusts for the tax-favored status

of net interest income from certain loans and investments using the statutory federal tax rate to increase tax-exempt interest income to a taxable equivalent basis. The company believes this measure to be the preferred industry measurement of net interest income and it enhances comparability of net interest income arising from taxable and tax-exempt sources.

The company presents certain additional non-GAAP financial measures to assist the reader with a better understanding of the company’s performance period over period, as well as to provide investors with assistance in understanding the success management has experienced in executing its strategic initiatives. These non-GAAP measures may reference the concept “operating.” The company uses the term “operating” to describe a financial measure that excludes income or expense considered to be nonoperating in nature. Items identified as nonoperating are those that, when excluded from a reported financial measure, provide management or the reader with a measure that may be more indicative of forward-looking trends in the company’s business.

Important Cautionary Statement about Forward-Looking Statements

This news release contains forward-looking statements within the meaning of section 27A of the Securities Act of 1933, as amended, and section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements that we may make include statements regarding our expectations of our performance and financial condition, balance sheet and revenue growth, the provision for credit losses, loan growth expectations, management’s predictions about charge-offs for loans, the impact of the COVID-19 pandemic on the economy and our operations, the adequacy of our enterprise risk management framework, the ongoing impact of future business combinations on our performance and financial condition, including our ability to successfully integrate the businesses, success of revenue-generating and cost reduction initiatives, the effectiveness of derivative financial instruments and hedging activities to manage risks, projected tax rates, increased cybersecurity risks, including potential business disruptions or financial losses, the adequacy of our internal controls over financial reporting, the financial impact of regulatory requirements and tax reform legislation, the impact of the change in the referenced rate reform, deposit trends, credit quality trends, the impact of natural or man-made disasters, the impact of PPP loans and forgiveness on our results, changes in interest rates, inflation, net interest margin trends, future expense levels, future profitability, improvements in expense to revenue (efficiency) ratio, purchase accounting impacts, accretion levels and expected returns.

Given the many unknowns and risks being heavily weighted to the downside, our forward-looking statements are subject to the risk that conditions will be substantially different than we are currently expecting. If efforts to contain and inoculate our population against COVID-19 and other variants thereof are unsuccessful and restrictions on movement are re-imposed, the economic impact could continue to be substantial. The COVID-19 outbreak and its consequences, including responsive measures to manage it, have had and are likely to continue to have an adverse effect, possibly materially, on our business and financial performance by adversely affecting, possibly materially, the demand and profitability of our products and services, the valuation of assets.

In addition, any statement that does not describe historical or current facts is a forward-looking statement. These statements often include the words “believes,” “expects,” “anticipates,” “estimates,” “intends,” “plans,” “forecast,” “goals,” “targets,” “initiatives,” “focus,” “potentially,” “probably,” “projects,” “outlook,” or similar expressions or future conditional verbs such as “may,” “will,” “should,” “would,” and “could.” Forward-looking statements are based upon the current beliefs and expectations of management and on information currently available to management. Our statements speak as of the date hereof, and we do not assume any obligation to update these statements or to update the reasons why actual results could differ from those contained in such statements in light of new information or future events. Forward-looking statements are subject to significant risks and uncertainties. Any forward-looking statement made in this release is subject to the safe harbor protections set forth in the Private Securities Litigation Reform Act of 1995. Investors are cautioned against placing undue reliance on

such statements. Actual results may differ materially from those set forth in the forward-looking statements. Additional factors that could cause actual results to differ materially from those described in the forward-looking statements can be found in Part I, “Item 1A. Risk Factors” in our Annual Report on Form 10-K for the year ended December 31, 2020 and in other periodic reports that we file with the SEC.

HANCOCK WHITNEY CORPORATION
FINANCIAL HIGHLIGHTS
(Unaudited)
	Three Months Ended									Twelve Months Ended
(dollars and common share data in thousands, except per share amounts)	12/31/2021			9/30/2021			12/31/2020			12/31/2021			12/31/2020
NET INCOME
Net interest income	$	229,296		$	234,709		$	238,286		$	933,235		$	942,523
Net interest income (TE) (a)		231,931			237,477			241,401			944,414			955,523
Provision for credit losses		(28,399	)		(26,955	)		24,214			(77,494	)		602,904
Noninterest income		89,612			93,361			82,350			364,334			324,428
Noninterest expense		182,462			194,703			193,144			807,007			788,792
Income tax expense (benefit)		27,102			30,740			(297	)		104,841			(79,571	)
Net income (loss)	$	137,743		$	129,582		$	103,575		$	463,215		$	(45,174	)
For informational purposes - included above, pre-tax
Nonoperating item included in noninterest income:
Gain on hurricane-related insurance settlement	$	3,600		$	—		$	—		$	3,600		$	—
Gain on sale of Hancock Horizon Funds		—			4,576			—			4,576			—
Gain on sale of Mastercard Class B common stock		—			—			—			2,800			—
Nonoperating items included in noninterest expense:
Efficiency initiatives		(649	)		(1,867	)		—			38,296			—
Hurricane related expenses		(680	)		5,092			—			4,412			—
Loss on redemption of subordinated notes		—			—			—			4,165			—
Provision for credit loss associated with energy loan sale		—			—			—			—			160,101
PERIOD-END BALANCE SHEET DATA
Loans	$	21,134,282		$	20,886,015		$	21,789,931		$	21,134,282		$	21,789,931
Securities		8,552,449			8,308,622			7,356,497			8,552,449			7,356,497
Earning assets		33,610,435			32,348,036			30,616,277			33,610,435			30,616,277
Total assets		36,531,205			35,318,308			33,638,602			36,531,205			33,638,602
Noninterest-bearing deposits		14,392,808			13,653,376			12,199,750			14,392,808			12,199,750
Total deposits		30,465,897			29,208,157			27,697,877			30,465,897			27,697,877
Common stockholders' equity		3,670,352			3,629,766			3,439,025			3,670,352			3,439,025
AVERAGE BALANCE SHEET DATA
Loans	$	20,770,130		$	20,941,173		$	22,065,672		$	21,207,942		$	22,166,523
Securities (b)		8,378,258			8,368,824			6,921,099			8,105,830			6,398,749
Earning assets		32,913,659			32,097,381			29,875,531			32,060,863			29,235,313
Total assets		35,829,027			35,207,960			33,067,462			35,075,392			32,390,967
Noninterest-bearing deposits		14,126,335			13,535,961			11,759,755			13,323,978			10,779,570
Total deposits		29,750,665			29,237,306			27,040,447			29,093,709			26,212,317
Common stockholders' equity		3,642,003			3,606,087			3,406,646			3,545,255			3,433,099
COMMON SHARE DATA
Earnings (loss) per share - diluted	$	1.55		$	1.46		$	1.17		$	5.22		$	(0.54	)
Cash dividends per share		0.27			0.27			0.27			1.08			1.08
Book value per share (period-end)		42.31			41.81			39.65			42.31			39.65
Tangible book value per share (period-end)		31.64			31.10			28.79			31.64			28.79
Weighted average number of shares - diluted		87,132			87,006			86,657			87,027			86,533
Period-end number of shares		86,749			86,823			86,728			86,749			86,728
Market data
High sales price	$	53.61		$	48.19		$	34.89		$	53.61		$	44.24
Low sales price		45.06			39.07			18.59			32.52			14.32
Period-end closing price		50.02			47.12			34.02			50.02			34.02
Trading volume		23,889			22,482			27,564			100,904			158,267
PERFORMANCE RATIOS
Return on average assets		1.53	%		1.46	%		1.25	%		1.32	%		(0.14	)%
Return on average common equity		15.00	%		14.26	%		12.10	%		13.07	%		(1.32	)%
Return on average tangible common equity		20.13	%		19.22	%		16.74	%		17.74	%		(1.82	)%
Tangible common equity ratio (c)		7.71	%		7.85	%		7.64	%		7.71	%		7.64	%
Net interest margin (TE)		2.80	%		2.94	%		3.22	%		2.95	%		3.27	%
Noninterest income as a percent of total revenue (TE)		27.87	%		28.22	%		25.44	%		27.84	%		25.35	%
Efficiency ratio (d)		56.57	%		57.44	%		58.23	%		57.29	%		60.07	%
Average loan/deposit ratio		69.81	%		71.62	%		81.60	%		72.90	%		84.57	%
Allowance for loan losses as a percentage of period-end loans		1.62	%		1.78	%		2.07	%		1.62	%		2.07	%
Allowance for credit losses as a percent of period-end loans (e)		1.76	%		1.92	%		2.20	%		1.76	%		2.20	%
Annualized net charge-offs to average loans		0.01	%		0.03	%		0.44	%		0.15	%		1.78	%
Allowance for loan losses to nonperforming loans + accruing loans 90 days past due		527.59	%		506.17	%		305.20	%		527.59	%		305.20	%
FTE headcount		3,486			3,429			3,986			3,486			3,986

(a) Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.

(b) Average securities does not include unrealized holding gains/losses on available for sale securities.

(c) The tangible common equity ratio is common shareholders' equity less intangible assets divided by total assets less intangible assets.

(d) The efficiency ratio is noninterest expense to total net interest income (TE) and noninterest income, excluding amortization of purchased intangibles and nonoperating items.

(e) The allowance for credit losses includes the allowance for loan and lease losses and the reserve for unfunded lending commitments.

HANCOCK WHITNEY CORPORATION
QUARTERLY FINANCIAL HIGHLIGHTS
(Unaudited)
	Three Months Ended
(dollars and common share data in thousands, except per share amounts)	12/31/2021			9/30/2021			6/30/2021			3/31/2021			12/31/2020
NET INCOME
Net interest income	$	229,296		$	234,709		$	234,643		$	234,587		$	238,286
Net interest income (TE) (a)		231,931			237,477			237,497			237,509			241,401
Provision for credit losses		(28,399	)		(26,955	)		(17,229	)		(4,911	)		24,214
Noninterest income		89,612			93,361			94,272			87,089			82,350
Noninterest expense		182,462			194,703			236,770			193,072			193,144
Income tax expense (benefit)		27,102			30,740			20,656			26,343			(297	)
Net income	$	137,743		$	129,582		$	88,718		$	107,172		$	103,575
For informational purposes - included above, pre-tax
Nonoperating item included in noninterest income:
Gain on hurricane-related insurance settlement	$	3,600		$	—		$	—		$	—		$	—
Gain on sale of Hancock Horizon Funds		—			4,576			—			—			—
Gain on sale of Mastercard Class B common stock		—			—			2,800			—			—
Nonoperating items included in noninterest expense:
Efficiency initiatives		(649	)		(1,867	)		40,812			—			—
Hurricane related expenses		(680	)		5,092			—			—			—
Loss on redemption of subordinated notes		—			—			4,165			—			—
PERIOD-END BALANCE SHEET DATA
Loans	$	21,134,282		$	20,886,015		$	21,148,530		$	21,664,859		$	21,789,931
Securities		8,552,449			8,308,622			8,633,133			8,005,990			7,356,497
Earning assets		33,610,435			32,348,036			32,075,450			32,134,637			30,616,277
Total assets		36,531,205			35,318,308			35,098,709			35,072,643			33,638,602
Noninterest-bearing deposits		14,392,808			13,653,376			13,406,385			13,174,911			12,199,750
Total deposits		30,465,897			29,208,157			29,273,107			29,210,520			27,697,877
Common stockholders' equity		3,670,352			3,629,766			3,562,901			3,416,903			3,439,025
AVERAGE BALANCE SHEET DATA
Loans	$	20,770,130		$	20,941,173		$	21,388,814		$	21,745,298		$	22,065,672
Securities (b)		8,378,258			8,368,824			8,194,812			7,468,541			6,921,099
Earning assets		32,913,659			32,097,381			32,195,515			31,015,637			29,875,531
Total assets		35,829,027			35,207,960			35,165,684			34,078,200			33,067,462
Noninterest-bearing deposits		14,126,335			13,535,961			13,237,796			12,374,235			11,759,755
Total deposits		29,750,665			29,237,306			29,228,809			28,138,763			27,040,447
Common stockholders' equity		3,642,003			3,606,087			3,488,592			3,441,466			3,406,646
COMMON SHARE DATA
Earnings per share - diluted	$	1.55		$	1.46		$	1.00		$	1.21		$	1.17
Cash dividends per share		0.27			0.27			0.27			0.27			0.27
Book value per share (period-end)		42.31			41.81			41.03			39.38			39.65
Tangible book value per share (period-end)		31.64			31.10			30.27			28.57			28.79
Weighted average number of shares - diluted		87,132			87,006			86,990			86,805			86,657
Period-end number of shares		86,749			86,823			86,847			86,777			86,728
Market data
High sales price	$	53.61		$	48.19		$	50.69		$	47.37		$	34.89
Low sales price		45.06			39.07			40.25			32.52			18.59
Period-end closing price		50.02			47.12			44.44			42.01			34.02
Trading volume		23,889			22,482			25,570			28,963			27,564
PERFORMANCE RATIOS
Return on average assets		1.53	%		1.46	%		1.01	%		1.28	%		1.25	%
Return on average common equity		15.00	%		14.26	%		10.20	%		12.63	%		12.10	%
Return on average tangible common equity		20.13	%		19.22	%		13.94	%		17.38	%		16.74	%
Tangible common equity ratio (c)		7.71	%		7.85	%		7.70	%		7.26	%		7.64	%
Net interest margin (TE)		2.80	%		2.94	%		2.96	%		3.09	%		3.22	%
Noninterest income as a percentage of total revenue (TE)		27.87	%		28.22	%		28.41	%		26.83	%		25.44	%
Efficiency ratio (d)		56.57	%		57.44	%		57.01	%		58.12	%		58.23	%
Average loan/deposit ratio		69.81	%		71.62	%		73.18	%		77.28	%		81.60	%
Allowance for loan losses as a percentage of period-end loans		1.62	%		1.78	%		1.89	%		1.96	%		2.07	%
Allowance for credit losses as a percentage of period-end loans (e)		1.76	%		1.92	%		2.03	%		2.11	%		2.20	%
Annualized net charge-offs to average loans		0.01	%		0.03	%		0.20	%		0.34	%		0.44	%
Allowance for loan losses to nonperforming loans + accruing loans 90 days past due		527.59	%		506.17	%		415.00	%		354.09	%		305.20	%
FTE headcount		3,486			3,429			3,626			3,926			3,986

(a) Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.

(b) Average securities does not include unrealized holding gains/losses on available for sale securities.

(c) The tangible common equity ratio is common shareholders' equity less intangible assets divided by total assets less intangible assets.

(d) The efficiency ratio is noninterest expense to total net interest income (TE) and noninterest income, excluding amortization of purchased intangibles and nonoperating items.

(e) The allowance for credit losses includes the allowance for loan and lease losses and the reserve for unfunded lending commitments.

HANCOCK WHITNEY CORPORATION
INCOME STATEMENT
(Unaudited)
	Three Months Ended									Twelve Months Ended
(dollars in thousands, except per share data)	12/31/2021			9/30/2021			12/31/2020			12/31/2021			12/31/2020
NET INCOME
Interest income	$	238,756		$	244,417		$	257,253		$	982,258		$	1,057,981
Interest income (TE) (f)		241,391			247,185			260,368			993,437			1,070,981
Interest expense		9,460			9,708			18,967			49,023			115,458
Net interest income (TE)		231,931			237,477			241,401			944,414			955,523
Provision for credit losses		(28,399	)		(26,955	)		24,214			(77,494	)		602,904
Noninterest income		89,612			93,361			82,350			364,334			324,428
Noninterest expense		182,462			194,703			193,144			807,007			788,792
Income (loss) before income taxes		164,845			160,322			103,278			568,056			(124,745	)
Income tax expense (benefit)		27,102			30,740			(297	)		104,841			(79,571	)
Net income (loss)	$	137,743		$	129,582		$	103,575		$	463,215		$	(45,174	)
For informational purposes - included above, pre-tax
Nonoperating item included in noninterest income:
Gain on hurricane-related insurance settlement	$	3,600		$	—		$	—		$	3,600		$	—
Gain on sale of Hancock Horizon Funds		—			4,576			—			4,576			—
Gain on sale of Mastercard Class B common stock		—			—			—			2,800			—
Nonoperating items included in noninterest expense:
Efficiency initiatives		(649	)		(1,867	)		—			38,296			—
Hurricane related expenses		(680	)		5,092			—			4,412			—
Loss on redemption of subordinated notes		—			—			—			4,165			—
Provision for credit loss associated with energy loan sale		—			—			—			—			160,101
NONINTEREST INCOME
Service charges on deposit accounts	$	21,346		$	21,159		$	19,864		$	81,032		$	76,659
Trust fees		15,547			16,041			14,801			62,898			58,191
Bank card and ATM fees		20,638			19,833			17,590			79,074			68,131
Insurance and investment commissions, and annuity fees		7,546			7,167			5,826			29,502			24,330
Secondary mortgage market operations		5,456			6,972			11,508			36,694			40,244
Other income		19,079			22,189			12,761			75,134			56,873
Total noninterest income	$	89,612		$	93,361		$	82,350		$	364,334		$	324,428
NONINTEREST EXPENSE
Personnel expense	$	108,128		$	111,978		$	112,245		$	482,375		$	464,059
Net occupancy and equipment expense		16,047			16,868			17,805			67,953			71,801
Other real estate and foreclosed assets expense (income), net		246			(376	)		367			(210	)		9,555
Other expense		54,122			62,151			58,113			240,224			223,461
Amortization of intangibles		3,919			4,082			4,614			16,665			19,916
Total noninterest expense	$	182,462		$	194,703		$	193,144		$	807,007		$	788,792
COMMON SHARE DATA
Earnings (loss) per share:
Basic	$	1.56		$	1.46		$	1.17		$	5.23		$	(0.54	)
Diluted		1.55			1.46			1.17			5.22			(0.54	)

(f) Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.

HANCOCK WHITNEY CORPORATION
INCOME STATEMENT
(Unaudited)
	Three Months Ended
(dollars in thousands, except per share data)	12/31/2021			9/30/2021			6/30/2021			3/31/2021			12/31/2020
NET INCOME
Interest income	$	238,756		$	244,417		$	248,300		$	250,785		$	257,253
Interest income (TE) (f)		241,391			247,185			251,154			253,707			260,368
Interest expense		9,460			9,708			13,657			16,198			18,967
Net interest income (TE)		231,931			237,477			237,497			237,509			241,401
Provision for credit losses		(28,399	)		(26,955	)		(17,229	)		(4,911	)		24,214
Noninterest income		89,612			93,361			94,272			87,089			82,350
Noninterest expense		182,462			194,703			236,770			193,072			193,144
Income before income taxes		164,845			160,322			109,374			133,515			103,278
Income tax expense (benefit)		27,102			30,740			20,656			26,343			(297	)
Net income	$	137,743		$	129,582		$	88,718		$	107,172		$	103,575
For informational purposes - included above, pre-tax
Nonoperating item included in noninterest income:
Gain on hurricane-related insurance settlement	$	3,600		$	—		$	—		$	—		$	—
Gain on sale of Hancock Horizon Funds		—			4,576			—			—			—
Gain on sale of Mastercard Class B common stock		—			—			2,800			—			—
Nonoperating items included in noninterest expense:
Efficiency initiatives		(649	)		(1,867	)		40,812			—			—
Hurricane related expenses		(680	)		5,092			—			—			—
Loss on redemption of subordinated notes		—			—			4,165			—			—
NONINTEREST INCOME
Service charges on deposit accounts	$	21,346		$	21,159		$	19,381		$	19,146		$	19,864
Trust fees		15,547			16,041			16,307			15,003			14,801
Bank card and ATM fees		20,638			19,833			20,483			18,120			17,590
Investment and insurance commissions, and annuity fees		7,546			7,167			7,331			7,458			5,826
Secondary mortgage market operations		5,456			6,972			12,556			11,710			11,508
Other income		19,079			22,189			18,214			15,652			12,761
Total noninterest income	$	89,612		$	93,361		$	94,272		$	87,089		$	82,350
NONINTEREST EXPENSE
Personnel expense	$	108,128		$	111,978		$	142,654		$	119,615		$	112,245
Net occupancy and equipment expense		16,047			16,868			17,347			17,691			17,805
Other real estate and foreclosed assets expense (income), net		246			(376	)		(86	)		6			367
Other expense		54,122			62,151			72,610			51,341			58,113
Amortization of intangibles		3,919			4,082			4,245			4,419			4,614
Total noninterest expense	$	182,462		$	194,703		$	236,770		$	193,072		$	193,144
COMMON SHARE DATA
Earnings per share:
Basic	$	1.56		$	1.46		$	1.00		$	1.21		$	1.17
Diluted		1.55			1.46			1.00			1.21			1.17

(f) Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.

HANCOCK WHITNEY CORPORATION

PERIOD-END BALANCE SHEET

(Unaudited)

(dollars in thousands)	12/31/2021			9/30/2021			6/30/2021			3/31/2021			12/31/2020
ASSETS
Commercial non-real estate loans	$	9,612,460		$	9,416,990		$	9,532,710		$	10,091,342		$	9,986,983
Commercial real estate - owner occupied loans		2,821,246			2,812,926			2,809,868			2,795,104			2,857,445
Total commercial and industrial loans		12,433,706			12,229,916			12,342,578			12,886,446			12,844,428
Commercial real estate - income producing loans		3,464,626			3,467,939			3,419,028			3,411,028			3,357,939
Construction and land development loans		1,228,670			1,213,991			1,295,036			1,122,141			1,065,057
Residential mortgage loans		2,423,890			2,351,053			2,412,459			2,488,792			2,665,212
Consumer loans		1,583,390			1,623,116			1,679,429			1,756,452			1,857,295
Total loans		21,134,282			20,886,015			21,148,530			21,664,859			21,789,931
Loans held for sale		93,069			90,618			90,002			124,677			136,063
Securities		8,552,449			8,308,622			8,633,133			8,005,990			7,356,497
Short-term investments		3,830,635			3,062,781			2,203,785			2,339,111			1,333,786
Earning assets		33,610,435			32,348,036			32,075,450			32,134,637			30,616,277
Allowance for loan losses		(342,065	)		(371,521	)		(399,668	)		(424,360	)		(450,177	)
Goodwill and other intangible assets		925,679			929,599			933,681			937,926			942,345
Other assets		2,337,156			2,412,194			2,489,246			2,424,440			2,530,157
Total assets	$	36,531,205		$	35,318,308		$	35,098,709		$	35,072,643		$	33,638,602
LIABILITIES
Noninterest-bearing deposits	$	14,392,808		$	13,653,376		$	13,406,385		$	13,174,911		$	12,199,750
Interest-bearing transaction and savings deposits		11,649,855			11,291,878			11,308,744			11,200,412			10,413,870
Interest-bearing public fund deposits		3,294,607			3,055,388			3,206,799			3,198,523			3,234,936
Time deposits		1,128,627			1,207,515			1,351,179			1,636,674			1,849,321
Total interest-bearing deposits		16,073,089			15,554,781			15,866,722			16,035,609			15,498,127
Total deposits		30,465,897			29,208,157			29,273,107			29,210,520			27,697,877
Short-term borrowings		1,665,061			1,745,228			1,516,508			1,652,747			1,667,513
Long-term debt		244,220			248,011			248,052			397,583			378,322
Other liabilities		485,675			487,146			498,141			394,890			455,865
Total liabilities		32,860,853			31,688,542			31,535,808			31,655,740			30,199,577
COMMON STOCKHOLDERS' EQUITY
Common stock net of treasury and capital surplus		2,065,214			2,084,387			2,080,486			2,073,658			2,067,450
Retained earnings		1,659,073			1,545,181			1,439,553			1,374,688			1,291,506
Accumulated other comprehensive income (loss)		(53,935	)		198			42,862			(31,443	)		80,069
Total common stockholders' equity		3,670,352			3,629,766			3,562,901			3,416,903			3,439,025
Total liabilities & stockholders' equity	$	36,531,205		$	35,318,308		$	35,098,709		$	35,072,643		$	33,638,602
For informational purposes only - included above
SBA Paycheck Protection Program (PPP) loans	$	531,059		$	935,330		$	1,417,523		$	2,345,605		$	2,005,237
CAPITAL RATIOS
Tangible common equity	$	2,744,673		$	2,700,167		$	2,629,220		$	2,478,977		$	2,496,680
Tier 1 capital (g)		2,890,408			2,799,037			2,692,065			2,622,973			2,534,049
Common equity as a percentage of total assets		10.05	%		10.28	%		10.15	%		9.74	%		10.22	%
Tangible common equity ratio		7.71	%		7.85	%		7.70	%		7.26	%		7.64	%
Leverage (Tier 1) ratio (g)		8.25	%		8.15	%		7.83	%		7.89	%		7.88	%
Common equity tier 1 (CET1) ratio (g)		11.16	%		11.17	%		10.98	%		11.00	%		10.61	%
Tier 1 risk-based capital ratio (g)		11.16	%		11.17	%		10.98	%		11.00	%		10.61	%
Total risk-based capital ratio (g)		12.92	%		13.06	%		12.94	%		13.60	%		13.22	%

(g) Estimated for most recent period-end. Regulatory capital ratios reflect the election to use the five-year transition rules for the adoption of ASC 326, commonly referred to as Current Expected Credit Loss, or CECL.

HANCOCK WHITNEY CORPORATION

AVERAGE BALANCE SHEET

(Unaudited)

	Three Months Ended									Twelve Months Ended
(in thousands)	12/31/2021			9/30/2021			12/31/2020			12/31/2021			12/31/2020
ASSETS
Commercial non-real estate loans	$	9,339,223		$	9,379,155		$	10,139,211		$	9,662,663		$	10,111,952
Commercial real estate - owner occupied loans		2,802,894			2,818,968			2,824,281			2,810,772			2,767,785
Total commercial and industrial loans		12,142,117			12,198,123			12,963,492			12,473,435			12,879,737
Commercial real estate - income producing loans		3,462,044			3,485,583			3,384,749			3,434,480			3,277,034
Construction and land development loans		1,198,638			1,234,637			1,081,734			1,162,337			1,114,123
Residential mortgage loans		2,365,798			2,376,500			2,732,483			2,445,602			2,857,584
Consumer loans		1,601,533			1,646,330			1,903,214			1,692,088			2,038,045
Total loans		20,770,130			20,941,173			22,065,672			21,207,942			22,166,523
Loans held for sale		77,405			82,588			104,415			90,231			86,842
Securities (h)		8,378,258			8,368,824			6,921,099			8,105,830			6,398,749
Short-term investments		3,687,866			2,704,796			784,345			2,656,860			583,199
Earning assets		32,913,659			32,097,381			29,875,531			32,060,863			29,235,313
Allowance for loan losses		(362,112	)		(392,767	)		(451,403	)		(406,082	)		(391,694	)
Goodwill and other intangible assets		927,571			931,584			944,572			933,701			951,875
Other assets		2,349,909			2,571,762			2,698,762			2,486,910			2,595,473
Total assets	$	35,829,027		$	35,207,960		$	33,067,462		$	35,075,392		$	32,390,967
LIABILITIES AND COMMON STOCKHOLDERS' EQUITY
Noninterest-bearing deposits	$	14,126,335		$	13,535,961		$	11,759,755		$	13,323,978		$	10,779,570
Interest-bearing transaction and savings deposits		11,405,136			11,341,034			10,229,569			11,216,503			9,558,071
Interest-bearing public fund deposits		3,057,776			3,085,452			3,160,372			3,140,185			3,232,133
Time deposits		1,161,418			1,274,859			1,890,751			1,413,043			2,642,543
Total interest-bearing deposits		15,624,330			15,701,345			15,280,692			15,769,731			15,432,747
Total deposits		29,750,665			29,237,306			27,040,447			29,093,709			26,212,317
Short-term borrowings		1,691,579			1,612,253			1,779,464			1,663,173			1,978,195
Long-term debt		245,369			248,019			385,313			314,903			320,274
Other liabilities		499,411			504,295			455,592			458,352			447,082
Common stockholders' equity		3,642,003			3,606,087			3,406,646			3,545,255			3,433,099
Total liabilities & stockholders' equity	$	35,829,027		$	35,207,960		$	33,067,462		$	35,075,392		$	32,390,967
For informational purposes only - included above
SBA Paycheck Protection Program (PPP) loans	$	708,435		$	1,172,276		$	2,216,458		$	1,523,718		$	1,566,889

(h) Average securities does not include unrealized holding gains/losses on available for sale securities.

HANCOCK WHITNEY CORPORATION

AVERAGE BALANCE AND NET INTEREST MARGIN SUMMARY

(Unaudited)

	Three Months Ended
	12/31/2021							9/30/2021							12/31/2020
(dollars in millions)	Average<br><br><br>Balance		Interest		Rate			Average<br><br><br>Balance		Interest		Rate			Average<br><br><br>Balance		Interest		Rate
AVERAGE EARNING ASSETS
Commercial & real estate loans (TE) (i)	$	16,802.8	$	150.7		3.56	%	$	16,918.4	$	150.3		3.52	%	$	17,430.0	$	157.1		3.59	%
Residential mortgage loans		2,365.8		20.5		3.46	%		2,376.5		21.5		3.63	%		2,732.5		26.6		3.90	%
Consumer loans		1,601.5		18.9		4.68	%		1,646.3		20.4		4.90	%		1,903.2		22.8		4.76	%
Loan fees & late charges		—		10.3		0.00	%		—		13.5		0.00	%		—		14.6		0.00	%
Total loans (TE) (j) (k)		20,770.1		200.4		3.83	%		20,941.2		205.7		3.90	%		22,065.7		221.1		3.99	%
Loans held for sale		77.4		0.6		3.02	%		82.6		0.6		3.06	%		104.4		0.5		1.99	%
US Treasury and government agency securities		418.4		1.6		1.60	%		395.6		1.6		1.59	%		196.0		0.9		1.85	%
CMOs and mortgage backed securities		7,019.6		30.5		1.74	%		7,033.7		31.4		1.79	%		5,781.5		30.7		2.12	%
Municipals (TE)		924.1		6.8		2.93	%		925.0		6.8		2.93	%		934.1		6.9		2.94	%
Other securities		16.2		0.1		3.50	%		14.5		0.1		3.56	%		9.5		0.1		4.20	%
Total securities (TE) (l)		8,378.3		39.0		1.86	%		8,368.8		39.9		1.91	%		6,921.1		38.6		2.23	%
Total short-term investments		3,687.9		1.4		0.15	%		2,704.8		1.0		0.15	%		784.3		0.2		0.10	%
Average earning assets yield (TE)	$	32,913.7	$	241.4		2.92	%	$	32,097.4	$	247.2		3.06	%	$	29,875.5	$	260.4		3.47	%
INTEREST-BEARING LIABILITIES
Interest-bearing transaction and savings deposits	$	11,405.1	$	1.3		0.04	%	$	11,341.0	$	1.7		0.06	%	$	10,229.6	$	4.2		0.16	%
Time deposits		1,161.4		0.8		0.27	%		1,274.9		1.0		0.32	%		1,890.7		3.8		0.80	%
Public funds		3,057.8		2.8		0.36	%		3,085.4		2.3		0.30	%		3,160.4		3.9		0.50	%
Total interest-bearing deposits		15,624.3		4.9		0.12	%		15,701.3		5.0		0.13	%		15,280.7		11.9		0.31	%
Short-term borrowings		1,691.6		1.5		0.34	%		1,612.3		1.5		0.36	%		1,779.4		1.7		0.37	%
Long-term debt		245.4		3.1		5.12	%		248.0		3.2		5.08	%		385.3		5.4		5.61	%
Total borrowings		1,937.0		4.6		0.95	%		1,860.3		4.7		0.99	%		2,164.7		7.1		1.30	%
Total interest-bearing liabilities cost		17,561.3		9.5		0.21	%		17,561.6		9.7		0.22	%		17,445.4		19.0		0.43	%
Net interest-free funding sources		15,352.4							14,535.8							12,430.1
Total cost of funds		32,913.7		9.5		0.11	%		32,097.4		9.7		0.12	%		29,875.5		19.0		0.25	%
Net Interest Spread (TE)			$	231.9		2.70	%			$	237.5		2.84	%			$	241.4		3.04	%
Net Interest Margin (TE)	$	32,913.7	$	231.9		2.80	%	$	32,097.4	$	237.5		2.94	%	$	29,875.5	$	241.4		3.22	%

(i) Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.

(j) Includes nonaccrual loans.

(k) Included in interest income is net purchase accounting accretion of $1.9 million, $1.6 million and $2.2 million for the three months ended December 31, 2021, September 30, 2021 and December 31, 2020, respectively.

(l) Average securities does not include unrealized holding gains/losses on available for sale securities.

HANCOCK WHITNEY CORPORATION
AVERAGE BALANCE AND NET INTEREST MARGIN SUMMARY
(Unaudited)
	Twelve Months Ended
	12/31/2021							12/31/2020
(dollars in millions)	Average<br><br><br>Balance		Interest		Rate			Average<br><br><br>Balance		Interest		Rate
AVERAGE EARNING ASSETS
Commercial & real estate loans (TE) (i)	$	17,070.3	$	606.1		3.55	%	$	17,270.9	$	660.5		3.82	%
Residential mortgage loans		2,445.6		90.6		3.70	%		2,857.6		112.1		3.92	%
Consumer loans		1,692.1		81.6		4.82	%		2,038.0		101.5		4.98	%
Loan fees & late charges		—		53.7		0.00	%		—		41.0		0.00	%
Total loans (TE) (j) (k)		21,208.0		832.0		3.92	%		22,166.5		915.1		4.13	%
Loans held for sale		90.2		2.5		2.82	%		86.8		2.6		3.02	%
US Treasury and government agency securities		330.6		5.4		1.64	%		153.5		3.2		2.09	%
CMOs and mortgage backed securities		6,833.1		122.3		1.79	%		5,345.0		121.8		2.28	%
Municipals (TE)		928.4		27.2		2.93	%		891.9		26.9		3.02	%
Other securities		13.7		0.5		3.66	%		8.4		0.4		4.28	%
Total securities (TE) (l)		8,105.8		155.4		1.92	%		6,398.8		152.3		2.38	%
Total short-term investments		2,656.9		3.5		0.13	%		583.2		1.0		0.17	%
Average earning assets yield (TE)	$	32,060.9	$	993.4		3.10	%	$	29,235.3	$	1,071.0		3.66	%
INTEREST-BEARING LIABILITIES
Interest-bearing transaction and savings deposits	$	11,216.5	$	9.1		0.08	%	$	9,558.1	$	25.6		0.27	%
Time deposits		1,413.0		6.5		0.46	%		2,642.5		37.1		1.40	%
Public funds		3,140.2		10.6		0.34	%		3,232.1		25.6		0.79	%
Total interest-bearing deposits		15,769.7		26.2		0.17	%		15,432.7		88.3		0.57	%
Short-term borrowings		1,663.2		6.0		0.36	%		1,978.2		10.0		0.51	%
Long-term debt		314.9		16.8		5.32	%		320.3		17.2		5.36	%
Total borrowings		1,978.1		22.8		1.15	%		2,298.5		27.2		1.18	%
Total interest-bearing liabilities cost		17,747.8		49.0		0.28	%		17,731.2		115.5		0.65	%
Net interest-free funding sources		14,313.1							11,504.1
Total cost of funds		32,060.9		49.0		0.15	%		29,235.3		115.5		0.39	%
Net Interest Spread (TE)			$	944.4		2.82	%			$	955.5		3.01	%
Net Interest Margin (TE)	$	32,060.9	$	944.4		2.95	%	$	29,235.3	$	955.5		3.27	%

(i) Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.

(j) Includes nonaccrual loans.

(k) Included in interest income is net purchase accounting accretion of $8.6 million and $15.4 million for the twelve months ended December 31, 2021 and 2020, respectively.

(l) Average securities does not include unrealized holding gains/losses on available for sale securities.

HANCOCK WHITNEY CORPORATION

ASSET QUALITY INFORMATION

(Unaudited)

	Three Months Ended									Twelve Months Ended
(dollars in thousands)	12/31/2021			9/30/2021			12/31/2020			12/31/2021			12/31/2020
Nonaccrual loans (m)	$	55,523		$	60,357		$	139,879		$	55,523		$	139,879
Restructured loans - still accruing		3,788			3,071			4,262			3,788			4,262
Total nonperforming loans		59,311			63,428			144,141			59,311			144,141
ORE and foreclosed assets		7,533			8,423			11,648			7,533			11,648
Total nonperforming assets	$	66,844		$	71,851		$	155,789		$	66,844		$	155,789
Nonperforming assets as a percentage of loans, ORE and foreclosed assets		0.32	%		0.34	%		0.71	%		0.32	%		0.71	%
Accruing loans 90 days past due	$	5,524		$	9,970		$	3,361		$	5,524		$	3,361
Accruing loans 90 days past due as a percentage of loans		0.03	%		0.05	%		0.02	%		0.03	%		0.02	%
Nonperforming assets + accruing loans 90 days past due to loans, ORE and foreclosed assets		0.34	%		0.39	%		0.73	%		0.34	%		0.73	%
PROVISION AND ALLOWANCE FOR CREDIT LOSSES:
Allowance for Loan Losses:
Beginning balance	$	371,521		$	399,668		$	448,674		$	450,177		$	191,251
Cumulative effect of change in accounting principle (n)		—			—			—			—			49,411
Provision for loan losses		(28,787	)		(26,377	)		25,833			(76,921	)		604,301
Charge-offs		(6,155	)		(6,755	)		(27,478	)		(50,836	)		(409,457	)
Recoveries		5,486			4,985			3,148			19,645			14,671
Net charge-offs		(669	)		(1,770	)		(24,330	)		(31,191	)		(394,786	)
Ending Balance	$	342,065		$	371,521		$	450,177		$	342,065		$	450,177
Reserve for Unfunded Lending Commitments:
Beginning balance	$	28,946		$	29,524		$	31,526		$	29,907		$	3,974
Cumulative effect of change in accounting principle (n)		—			—			—			—			27,330
Provision for losses on unfunded lending commitments		388			(578	)		(1,619	)		(573	)		(1,397	)
Ending Balance	$	29,334		$	28,946		$	29,907		$	29,334		$	29,907
Total Allowance for Credit Losses	$	371,399		$	400,467		$	480,084		$	371,399		$	480,084
Total Provision for Credit Losses	$	(28,399	)	$	(26,955	)	$	24,214		$	(77,494	)	$	602,904
Allowance for loan losses as a percentage of period-end loans		1.62	%		1.78	%		2.07	%		1.62	%		2.07	%
Allowance for credit losses as a percentage of period-end loans		1.76	%		1.92	%		2.20	%		1.76	%		2.20	%
Allowance for loan losses to nonperforming loans + accruing loans 90 days past due		527.59	%		506.17	%		305.20	%		527.59	%		305.20	%
NET CHARGE-OFF INFORMATION
Net charge-offs (recoveries):
Commercial & real estate loans	$	(502	)	$	536		$	22,141		$	25,497		$	384,225
Residential mortgage loans		(31	)		(485	)		(166	)		(746	)		(1,074	)
Consumer loans		1,202			1,719			2,355			6,440			11,635
Total net charge-offs	$	669		$	1,770		$	24,330		$	31,191		$	394,786
Net charge-offs (recoveries) as a percentage of average loans:
Commercial & real estate loans		(0.01	)%		0.01	%		0.51	%		0.15	%		2.22	%
Residential mortgage loans		(0.01	)%		(0.08	)%		(0.02	)%		(0.03	)%		(0.04	)%
Consumer loans		0.30	%		0.41	%		0.49	%		0.38	%		0.57	%
Total net charge-offs as a percentage of average loans		0.01	%		0.03	%		0.44	%		0.15	%		1.78	%
For informational purposes - included above
Provision for credit loss associated with energy loan sale	$	—		$	—		$	—		$	—		$	160,101
Charge-offs associated with energy loan sale		—			—			—			—			242,628

(m) Included in nonaccrual loans are nonaccruing restructured loans totaling $6.8 million, $7.2 million and $21.6 million at December 31, 2021, September 30, 2021 and December 31, 2020, respectively.

(n) Represents the increase in the allowance upon the January 1, 2020 adoption of ASC 326, commonly referred to as Current Expected Credit Losses, or CECL.

HANCOCK WHITNEY CORPORATION

ASSET QUALITY INFORMATION

(Unaudited)

	Three Months Ended
(dollars in thousands)	12/31/2021			9/30/2021			6/30/2021			3/31/2021			12/31/2020
Nonaccrual loans (m)	$	55,523		$	60,357		$	83,551		$	108,434		$	139,879
Restructured loans - still accruing		3,788			3,071			3,830			6,320			4,262
Total nonperforming loans		59,311			63,428			87,381			114,754			144,141
ORE and foreclosed assets		7,533			8,423			10,201			9,467			11,648
Total nonperforming assets	$	66,844		$	71,851		$	97,582		$	124,221		$	155,789
Nonperforming assets as a percentage of loans, ORE and foreclosed assets		0.32	%		0.34	%		0.46	%		0.57	%		0.71	%
Accruing loans 90 days past due (o)	$	5,524		$	9,970		$	8,925		$	5,090		$	3,361
Accruing loans 90 days past due as a percentage of loans		0.03	%		0.05	%		0.04	%		0.02	%		0.02	%
Nonperforming assets + accruing loans 90 days past due to loans, ORE and foreclosed assets		0.34	%		0.39	%		0.50	%		0.60	%		0.73	%
PROVISION AND ALLOWANCE FOR CREDIT LOSSES:
Allowance for loan losses	$	342,065		$	371,521		$	399,668		$	424,360		$	450,177
Reserve for unfunded lending commitments		29,334			28,946			29,524			32,559			29,907
Total allowance for credit losses	$	371,399		$	400,467		$	429,192		$	456,919		$	480,084
Total provision for credit losses	$	(28,399	)	$	(26,955	)	$	(17,229	)	$	(4,911	)	$	24,214
Allowance for loan losses as a percentage of period-end loans		1.62	%		1.78	%		1.89	%		1.96	%		2.07	%
Allowance for credit losses as a percentage of period-end loans		1.76	%		1.92	%		2.03	%		2.11	%		2.20	%
Allowance for loan losses to nonperforming loans + accruing loans 90 days past due		527.59	%		506.17	%		415.00	%		354.09	%		305.20	%
NET CHARGE-OFF INFORMATION
Net charge-offs (recoveries)
Commercial & real estate loans	$	(502	)	$	536		$	9,257		$	16,206		$	22,141
Residential mortgage loans		(31	)		(485	)		(133	)		(97	)		(166	)
Consumer loans		1,202			1,719			1,374			2,145			2,355
Total net charge-offs	$	669		$	1,770		$	10,498		$	18,254		$	24,330
Net charge-offs (recoveries) as a percentage of average loans:
Commercial & real estate loans		(0.01	)%		0.01	%		0.22	%		0.38	%		0.51	%
Residential mortgage loans		(0.01	)%		(0.08	)%		(0.02	)%		(0.02	)%		(0.02	)%
Consumer loans		0.30	%		0.41	%		0.32	%		0.48	%		0.49	%
Total net charge-offs as a percentage of average loans:		0.01	%		0.03	%		0.20	%		0.34	%		0.44	%
AVERAGE LOANS
Commercial & real estate loans	$	16,802,799		$	16,918,343		$	17,233,112		$	17,334,265		$	17,429,975
Residential mortgage loans		2,365,798			2,376,500			2,442,956			2,600,492			2,732,483
Consumer loans		1,601,533			1,646,330			1,712,746			1,810,541			1,903,214
Total average loans	$	20,770,130		$	20,941,173		$	21,388,814		$	21,745,298		$	22,065,672

(m) Included in nonaccrual loans are nonaccruing restructured loans totaling $6.8 million, $7.2 million, $6.8 million, $7.2 million and $21.6 million at December 31, 2021, September 30, 2021, June 30, 2021, March 31, 2021 and December 31, 2020, respectively.

(o) Excludes 90+ accruing loan troubled debt restructured loans already reflected in total nonperforming loans of $1.8 million at March 31, 2021.

HANCOCK WHITNEY CORPORATION

Appendix A to the Earnings Release

Reconciliation of Non-GAAP Measures

TOTAL REVENUE (TE) AND PRE-PROVISION NET REVENUE (TE)

	Three Months Ended															Twelve Months Ended
(in thousands)	12/31/2021			9/30/2021			6/30/2021			3/31/2021			12/31/2020			12/31/2021			12/31/2020
Net interest income	$	229,296		$	234,709		$	234,643		$	234,587		$	238,286		$	933,235		$	942,523
Noninterest income		89,612			93,361			94,272			87,089			82,350			364,334			324,428
Total revenue		318,908			328,070			328,915			321,676			320,636			1,297,569			1,266,951
Taxable equivalent adjustment (p)		2,635			2,768			2,854			2,922			3,115			11,179			13,000
Nonoperating revenue		(3,600	)		(4,576	)		(2,800	)		—			—			(10,976	)		—
Operating revenue (TE)		317,943			326,262			328,969			324,598			323,751			1,297,772			1,279,951
Noninterest expense		(182,462	)		(194,703	)		(236,770	)		(193,072	)		(193,144	)		(807,007	)		(788,792	)
Nonoperating expense		(1,329	)		3,225			44,977			—			—			46,873			—
Operating pre-provision net revenue (TE)	$	134,152		$	134,784		$	137,176		$	131,526		$	130,607		$	537,638		$	491,159

(p) Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.

17

hwc-ex992_6.pptx.htm

Fourth Quarter 2021 Earnings Conference Call 1/18/2022 HANCOCK WHITNEY Exhibit 99.2

This presentation contains forward-looking statements within the meaning of section 27A of the Securities Act of 1933, as amended, and section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements that we may make include statements regarding our expectations of our performance and financial condition, balance sheet and revenue growth, the provision for credit losses, loan growth expectations, management’s predictions about charge-offs for loans, the impact of the COVID-19 pandemic on the economy and our operations, the adequacy of our enterprise risk management framework, the ongoing impact of future business combinations on our performance and financial condition, including our ability to successfully integrate the businesses, success of revenue-generating and cost reduction initiatives, the effectiveness of derivative financial instruments and hedging activities to manage risks, projected tax rates, increased cybersecurity risks, including potential business disruptions or financial losses, the adequacy of our internal controls over financial reporting, the financial impact of regulatory requirements and tax reform legislation, the impact of the change in the referenced rate reform, deposit trends, credit quality trends, the impact of natural or man-made disasters, the impact of PPP loans and forgiveness on our results, changes in interest rates, inflation, net interest margin trends, future expense levels, future profitability, improvements in expense to revenue (efficiency) ratio, purchase accounting impacts, accretion levels and expected returns. Also, any statement that does not describe historical or current facts is a forward-looking statement. These statements often include the words “believes,” “expects,” “anticipates,” “estimates,” “intends,” “plans,” “forecast,” “goals,” “targets,” “initiatives,” “focus,” “potentially,” “probably,” “projects,” “outlook," or similar expressions or future conditional verbs such as “may,” “will,” “should,” “would,” and “could.” Forward-looking statements are based upon the current beliefs and expectations of management and on information currently available to management. Our statements speak as of the date hereof, and we do not assume any obligation to update these statements or to update the reasons why actual results could differ from those contained in such statements in light of new information or future events. Given the many unknowns and risks being heavily weighted to the downside, our forward-looking statements are subject to the risk that conditions will be substantially different than we are currently expecting. If efforts to contain and inoculate our population against COVID-19 and other variants thereof are unsuccessful and restrictions on movement are re-imposed, the economic impact could continue to be substantial. The COVID-19 outbreak and its consequences, including responsive measures to manage it, have had and are likely to continue to have an adverse effect, possibly materially, on our business and financial performance by adversely affecting, possibly materially, the demand and profitability of our products and services, the valuation of assets. Forward-looking statements are subject to significant risks and uncertainties. Any forward-looking statement made in this release is subject to the safe harbor protections set forth in the Private Securities Litigation Reform Act of 1995. Investors are cautioned against placing undue reliance on such statements. Actual results may differ materially from those set forth in the forward-looking statements. Additional factors that could cause actual results to differ materially from those described in the forward-looking statements can be found in Part I, “Item 1A. Risk Factors” in our Annual Report on Form 10-K for the year ended December 31, 2020 and in other periodic reports that we file with the SEC. Important cautionary statement about forward-looking statements HNCOCK WHITNEY 2

Non-GAAP Reconciliations & Glossary of Terms Throughout this presentation we may use non-GAAP numbers to supplement the evaluation of our performance. The items noted below with an asterisk, "*", are considered non-GAAP. These non-GAAP financial measures should not be considered alternatives to GAAP-basis financial statements, and other bank holding companies may define or calculate these non-GAAP measures or similar measures differently. Reconciliations of those non-GAAP measures to the comparable GAAP measure are included in the appendix to this presentation. The earnings release, financial tables and supporting slide presentation can be found on the company’s Investor Relations website at investors.hancockwhitney.com. AFS – Available for sale securities ACL – Allowance for credit losses Annualized – Calculated to reflect a rate based on a full year B – Dollars in billions bps – basis points CARES Act – Coronavirus Aid Relief, and Economic Security Act CCB – Capital Conservation Buffer C&D – Construction and land development loans C&I – Commercial and industrial loans CDI – Core Deposit Intangible CECL – Current Expected Credit Losses (accounting standard effective 1/1/2020) CET1 – Common Equity Tier 1 Ratio Core Loans - Loans excluding PPP activity COVID-19 – Pandemic related virus CRE – Commercial real estate DDA – Noninterest-bearing demand deposit accounts DP – Data processing (e) – estimated *Efficiency ratio – noninterest expense to total net interest (TE) and noninterest income, excluding amortization of purchased intangibles and nonoperating items EOP – End of period EPS – Earnings per share Excess liquidity - deposits held at the Fed plus investment in the bond portfolio above normal levels Fed - Federal Reserve Bank FTE – Full time equivalent FV – Fair Value HFS – Held for sale HTM – Held to maturity securities ICRE – Income-producing commercial real estate IRR – Interest rate risk LIBOR – London Inter-Bank Offered Rate Line Utilization - represents the used portion of a revolving line resulting in a funded balance for a given portfolio; credit cards, construction loans (commercial and residential), and consumer lines of credit are excluded from the calculation Linked-quarter (LQ) – current quarter compared to previous quarter LOB – Line of Business LQA – Linked-quarter annualized M&A – Mergers and acquisitions MM – Dollars in millions MMDDYY – Month Day Year NII – Net interest income *NIM – Net interest margin (TE) NPA – Nonperforming assets NPL – Nonperforming loans OCI – Other comprehensive income OFA – Other foreclosed assets *Operating – Financial measure excluding nonoperating items *Operating Leverage – Operating revenue (TE) less operating expense; also known as PPNR ORE – Other real estate PAA – Purchase accounting accretion from business combinations *PPNR – Pre-provision net revenue (operating); also known as operating leverage PPP – SBA’s Paycheck Protection Program related to COVID-19 PY – Prior year ROA – Return on average assets ROTCE – Return on tangible common equity SBA – Small Business Administration S1 – Stronger Near-term Growth S2 – Slower Near-term Growth Structured solutions – active term modification of original contractual loan agreement TCE – Tangible common equity ratio (common shareholders’ equity less intangible assets divided by total assets less intangible assets) TDR – Troubled Debt Restructuring *TE – Taxable equivalent (calculated using the current statutory federal tax rate) VERP – Voluntary Early Retirement Program XHYY – Half Year XQYY – Quarter Year Y-o-Y – Year over year HNCOCK WHITNEY 3

Corporate Profile (as of December 31, 2021) $36.5 billion in Total Assets $21.1 billion in Total Loans $30.5 billion in Total Deposits CET1 ratio 11.16%(e) Tangible Common Equity (TCE) ratio 7.71% $4.3 billion in Market Capitalization 177 banking locations and 240 ATMs across our footprint Approximately 3,500 (FTE) employees corporate-wide Moody’s long-term issuer rating: Baa3; outlook stable S&P long-term issuer rating: BBB; outlook stable Named one of America’s Best Midsize Employers by Forbes Rated among the strongest, safest financial institutions in the country by BauerFinancial, Inc. for 129 consecutive quarters Earned top customer service marks with Greenwich Excellence Awards Diversity, equity and inclusion (DEI) are fundamental to the spirit of HWC’s purpose, mission and values HWC Nasdaq Listed HNCOCK WHITNEY 4

Fourth Quarter 2021 Highlights Net income totaled $137.7 million, or $1.55 per diluted share, up $8.2 million, or $0.09 per share, linked quarter 4Q21 results include ($4.9) million, or ($0.04) per share, of net nonoperating income items; 3Q21 results included ($1.4) million, or ($0.01) per share, of net nonoperating income items Excluding the impact of nonoperating items, EPS would be $1.51, up $0.06 linked quarter Operating pre-provision net revenue (PPNR)* totaled $134.2 million, down less than 1%, linked-quarter Core loan growth of $652.5 million, or 13% LQA, more than offset the impact of $404.3 million in PPP loan forgiveness leading to an overall increase in total loans of $248.3 million, or 4.8% LQA Deposits increased $1.3 billion, or 17% LQA, as noninterest-bearing demand deposits increased $739.4 million resulting from Hurricane Ida recovery proceeds and interest-bearing accounts increased $518.3 million mainly from seasonal public funds deposits $29.1 million reserve release and $0.7 million in net charge-offs led to a negative provision for credit losses of $28.4 million ACL coverage remained strong at 1.76%; 1.80% excl PPP loans Both nonperforming loans and criticized commercial loans declined 6% and 2%, respectively linked-quarter The continued impact of excess liquidity, driven mainly by PPP loan forgiveness and Hurricane Ida related deposits, led to a 14 bps compression in reported NIM TCE ratio 7.71%, down 14 bps ($s in millions; except per share data) 4Q21 3Q21 4Q20 Net Income $137.7 $129.6 $103.6 Provision for credit losses (28.4) (27.0) 24.2 Net nonoperating (income)/expense items (4.9) (1.4) ─ Earnings Per Share – diluted $1.55 $1.46 $1.17 Return on Assets (%) (ROA) 1.53 1.46 1.25 Return on Tangible Common Equity (%) (ROTCE) 20.13 19.22 16.74 Net Interest Margin (TE) (%) 2.80 2.94 3.22 Net Charge-offs (%) 0.01 0.03 0.44 CET1 Ratio (%) 11.16(e) 11.17 10.61 Tangible Common Equity (%) 7.71 7.85 7.64 Pre-Provision Net Revenue (TE)* $134.2 $134.8 $130.6 Efficiency Ratio (%) 56.6 57.4 58.2 *Non-GAAP measure: see appendix for non-GAAP reconciliation HNCOCK WHITNEY 6

2021 Highlights Net income of $463.2 million, or $5.22 per diluted share, compared to a net loss of $45.2 million, or ($.54), in 2020 Results include $35.9 million, or $0.31 per share, of net nonoperating expense items, mostly related to efficiency initiatives Operating pre-provision net revenue (PPNR)* totaled $537.6 million, up $46.5 million, or 9%, compared to 2020 Negative provision for credit losses of $77.5 million in 2021 compared to a provision for credit losses of $602.9 million in 2020 2020 provision for credit losses included $160.1 million related to energy loan bulk sale and $442.8 million largely related to the economic impact on borrowers from the pandemic Core loan growth of $818.5 million, or 4.1%, partially offset the impact of $1.5 billion in net PPP loan forgiveness resulting in an overall decrease in total loans of $655.6 million for the year Deposits increased $2.8 billion, or 10.0%, mainly attributed to stimulus funding and Hurricane Ida recovery proceeds Criticized commercial loans declined $106 million, or 27%, and nonperforming loans declined $85 million, or 59%, from a year earlier NIM declined 32 bps to 2.95% reflecting the continued impact from historic levels of excess liquidity and the low rate environment *Non-GAAP measure: see appendix for non-GAAP reconciliation ($s in millions; except per share data) 2021 2020 Net Income (loss) $463.2 ($45.2) Provision for credit losses excluding energy loan sale (77.5) 442.8 Provision related to energy loan sale -— 160.1 Net nonoperating (income)/expense items 35.9 -— Earnings (loss) Per Share – diluted $5.22 ($.54) Return on Assets (%) (ROA) 1.32 (0.14) Return on Tangible Common Equity (%) (ROTCE) 17.74 (1.82) Net Interest Margin (TE) (%) 2.95 3.27 Net Charge-offs (%) 0.15 1.78 CET1 Ratio (%) 11.16(e) 10.61 Tangible Common Equity (%) 7.71 7.64 Pre-Provision Net Revenue (TE)* $537.6 $491.2 Efficiency Ratio (%) 57.3 60.1

Loans totaled $21.1 billion, up $248.3 million, net, linked-quarter $652.5 million in core loan growth, or 13% LQA $404.3 million in PPP loan forgiveness Quarterly core loan growth (excl PPP) impacted by: Growth across entire footprint Increased loan pipeline pull-through rate Tailwinds and headwinds to future core loan growth: Tailwinds: Improvement in economic activity across our footprint Deployment of excess liquidity Improvement of utilization rates Headwinds: Amortizing only indirect portfolio No new production planned in the energy sector Higher than projected payoffs and paydowns Core Loan Growth Accelerates in 4Q Driving a Strong Finish to 2021 Bar Chart

Higher Production Levels Driving Loan Growth; Yield on New Loans Impacted By Rate Environment * Excluding PPP loans

Paycheck Protection Program (PPP) Loans Under the original and extended Paycheck Protection Programs (PPP), the company originated more than 20,000 loans totaling $3.3 billion During 4Q21, $404.3 million in PPP loans were forgiven Expect majority of remaining PPP loans to be forgiven by 2Q22; minimal impact from PPP in 2H22 Unamortized fees totaled $7.3 million as of December 31, 2021   Quarterly Impact $ in millions except per share data EOP PPP Net Income PPNR Fees Amortized NIM EPS 2Q20 $2,287 $12.8 $16.2 $13.0 0.05% $0.15 3Q20 2,324 15.3 19.3 17.0 0.06% 0.17 4Q20 2,005 14.7 18.6 15.7 0.05% 0.17 1Q21 2,346 14.3 18.2 14.2 0.04% 0.16 2Q21 1,418 15.8 20.0 16.9 0.09% 0.18 3Q21 935 11.9 15.3 14.4 0.11% 0.13 4Q21 531 8.4 10.9 10.3 0.09% 0.09 West 25% Central 39% East 36% HNCOCK WHITNEY 7

NPLs, Criticized Commercial Loans Continue Improvement To Among Best in Class Criticized commercial loans totaled $287 million, or 1.73% of total commercial loans (excluding PPP loans), at December 31, 2021, down $7 million, or 2%, linked-quarter and down $106 million, or 27%, from a year ago Nonperforming loans totaled $59 million, or 0.29% of total loans (excluding PPP loans), at December 31, 2021, down $4 million, or 6%, linked-quarter and down $85 million, or 59%, from a year ago *Ratios exclude PPP loans Total Loans excl. PPP $19,784 $19,319 $19,731 $19,951 $20,603 Total Commercial Loans excl. PPP 15,262 15,074 15,639 15,977 16,596 Criticized Commercial Loans 393 348 330 294 287 Total Nonperforming Loans 144 115 87 63 59 2.31% 0.59% 2.11% 0.44% 0.32% 1.73% 0.29% $700 $600 $500 $400 $300 $200 $100 $0 3Q20 4Q20 1Q21 2Q21 3Q21 HNCOCK WHITNEY 12

Modest Reserve Release Continues Negative provision for the quarter of ($28.4) million, reflects $0.7 million of net charge-offs and a reserve release of $29.1 million Weighting applied to Moody's December 2021 economic scenarios was 40% Baseline and 60% slower growth (S2), compared to 50% Baseline and 50% slower growth in the prior quarter Scenario mix and weighting captures potential for slower near term economic growth than provided for in the baseline scenario Significant assumptions in economic forecasts include varied size and timing of government infrastructure spend, and resolution or containment of the coronavirus pandemic  ($s in millions) Net Charge-Offs Reserve Release Total Provision Commercial ($0.5) ($27.3) ($27.8) Mortgage ---  (0.4) (0.4) Consumer 1.2 (1.4) (0.2) Total $0.7 ($29.1) ($28.4) 12/31/2021 9/30/2021 Portfolio ($ in millions) Amount % of Loan and Leases Outstanding Amount % of Loan and Leases Outstanding Commercial (excluding PPP) $279 1.68% $307 1.92% Mortgage 30 1.26% 31 1.32% Consumer 32 2.02% 33 2.05% PPP Loans 1 0.10% 1 0.10% Allowance for Loan and Lease Losses $342 1.62% $372 1.78% Reserve for Unfunded Lending Commitments 29 --- 29 ---  Allowance for Credit Losses $371 1.76% $401 1.92% Allowance for Credit Losses – Excluding PPP Loans $370 1.80% $400 2.00%

Securities Portfolio Positioned Well for Future Rise in Rates Securities portfolio (excluding unrealized gains) totaled $8.6 billion, up $299 million, or 4%, linked-quarter 18% HTM, 82% AFS $1.8 billion, or 26% of AFS securities, are FV hedged, and provide OCI protection and flexibility to reposition and/or reprice portfolio in a rising rate environment Yield 1.86%, down 5 bps linked-quarter Purchases during 4Q21 of $570 million at yield of 1.58% included $300 million of liquidity deployment and $270 million in reinvestment of runoff on bond portfolio Unrealized net gain of $2.2 million on AFS at December 31, 2021 compared to $57.4 million at September 30, 2021 Premium amortization totaled $12.2 million, down $0.1 million linked-quarter Effective duration of 4.25 years at year-end compared to 4.41 years at September 30, 2021 Securities Portfolio Mix 12/31/20 $s in millions CMBS $2,873 41% CMO $513 7% U.S. Agencies and other $219 3% RMBS $2,582 36% Munis $936 13% HNCOCK WHITNEY 15 Bar chart,pie chart

Seasonality and Hurricane Recovery Proceeds Drive Quarterly Growth Total deposits of $30.5 billion, up $1.3 billion, or 4.3%, linked-quarter Noninterest-bearing demand deposits (DDAs) increased $739.4 million due to hurricane recovery proceeds and seasonal deposit inflows Interest-bearing public fund deposits increased $239.2 million primarily relating to normal deposit inflows that typically begin to runoff in the first quarter of each year Time deposits decreased $78.9 million, with a portion moving to transaction accounts in light of the low rate environment DDAs comprised 47% of total period-end deposits December cost of deposits 6 bps, down 1 bp from September 2021 Total Deposits 12/31/20 $s in millions Time Deposits (retail) $1,835 7% Time Deposits (brokered) $14 ― Interest-bearing public funds $3,235 12% Interest-bearing transaction & savings $10,414 37% Noninterest bearing $12,200 44% $s in billions Avg Qtrly Deposits LQA EOP growth $28.0 $26.0 $24.0 $22.0 $20.0 $18.0 $16.0 1Q20 $24.3 20% 2Q20 $26.7 37% 3Q20 $26.8 -4% 4Q20 $27.0 10% 1Q21 $27.0 10% HNCOCK WHITNEY 15 Bar chart,pie chart

Net interest margin (NIM) 2.80%, down 14 bps linked-quarter NIM Headwinds: Ongoing impact of lower rates PPP loan forgiveness Continued elevated excess liquidity NIM Tailwinds: Deployment of excess liquidity into loans/bonds Steeper yield curve and potential 2022 rate increases Excess Liquidity Once Again Drives NIM Compression Cost of Deposits 0.60% 0.50% 0.40% 0.30% 0.20% 0.10% Mar-20 Apr-20 May-20 Jun 20 Jul-20 Aug-20 Sep-20 Oct-20 Nov-20 Dec-20 Mar-21e .59% .41% .33% .29% .25% .21% .20% .19% .17% .17% .13% 3.40% 3.30% 3.20% 3.10% 3.00% 2.90% 2.80% 3Q20 NIM (TE) Impact of Securities Portfolio Purchase/Premium amortization Impact of change in earnings asset mix Lower cost of deposits Net impact of interest reversals and recoveries/loan fees accretion 4Q20 NIM (TE) 0.02% 0.06% 0.05% 0.02% 5.00% 4.00% 3.00% 2.00% 1.00% 0.00% 4Q19 1Q20 2Q20 3Q20 4Q20 4.69% 3.43% 2.56% 0.76% 4.56% 3.41% 2.53% 0.67% 4.04% 3.23% 2.47% 0.38% 3.95% 3.23% 2.31% 0.30% 3.99% 3.22% 2.23% 0.25% Loan Yield Securities Yield Cost of Fund NIM HNCOCK WHITNEY 18 Line chart

Loans Loans, excluding PPP, totaled $20.6 billion at December 31, 2021 57% variable, 43% fixed 61% ($7.1 billion) of variable loans are LIBOR-based (34% of loan portfolio excluding PPP) 34% ($3.9 billion) of variable loans tied to Wall Street Journal Prime $4.0 billion of variable loans have a floor ≥ 25 bps Securities Planned investment of $1.5 billion of excess liquidity into bond portfolio started in 4Q21 with purchases of $570 million ($300 million with excess liquidity and $270 million in reinvestment of runoff on bond portfolio) at an average yield of 1.58% Will continue similar investment strategy to grow portfolio approximately $300 million per quarter through 4Q22 Swaps/ Hedges $1.1 billion of active receive fixed/pay 1 month LIBOR swaps designated as Cash Flow Hedges on the balance sheet Receive 149 bps/pay 1 month LIBOR No Cash Flow Hedges were terminated in the 4Q21 $1.8 billion of pay fixed/receive Fed Effective swaps designated as Fair Value Hedges on $2.1 billion of securities FV hedges have starting effective dates beginning in June 2023 through August 2025 At that point we pay fixed 1.32% and receive the fed fund effective rate (result is variable rate of FF+33 bps) 26% of AFS investment securities on the balance sheet Deposits Deposits totaled $30.5 billion at December 31, 2021 85% of deposits are low-interest (MMDA, savings) or noninterest bearing (DDA) Strategy will be to lag increases in deposit rates with any Fed rate increases Expect shift in deposit mix as interest rates begin to rise Rate Betas Historical loan betas 48% (4Q15 – 3Q19) Historical deposit betas 25% (4Q15 – 3Q19, excluding brokered CDs) Rate Floors Floor Rate Balance * Balance Cumulative 25-49 bps $670 million $670 million 50-74 bps $804 million $1.5 billion 75-99 bps $546 million $2.0 billion 100-150 bps $1.8 billion $3.8 billion > 150 bps $172 million $4.0 billion IRR Sensitivity Table HWC (Hedges Removed) As of 4Q21 As of 4Q21 Peers * Immediate 100 bps 7.3% 8.4% 7.3% Gradual 100 bps 3.2% 3.6% 4.3% Deposits $ in millions Time Deposits $1,129 4% Interest-bearing public funds $3,295 11% Interest-bearing transaction & savings $11,650 38% Noninterest bearing $14,393 47% IRR Sensitivity Rate Floors Floor Rate Balance * Balance Cumulative 25-49 bps $670 million $670 million 50-74 bps $804 million $1.5 billion 75-99 bps $546 million $2.0 billion 100-150 bps $1.8 billion $3.8 billion > 150 bps $172 million $4.0 billion *excludes mortgage, credit cards, HELOCs IRR Sensitivity Table     HWC   HWC (Hedges Removed)     As of 4Q21 As of 4Q21 Peers * Immediate 100 bps 7.3% 8.4% 7.3% Gradual 100 bps 3.2% 3.6% 4.3% * Source: S&P Global Market Intelligence company public filings as of 3Q21

Core Fee Income Stable; Specialty Income Drives Total Decline Noninterest income totaled $89.6 million, down $3.7 million, or 4% linked-quarter; operating noninterest income totaled $86.0 million, down $2.8 million, or 3% linked-quarter 4Q21 included a $3.6 million gain from storm-related insurance proceeds (nonoperating item) 3Q21 included a $4.6 million gain from the sale of the remaining Hancock Horizon Funds (nonoperating item) The decrease in other noninterest income is primarily related to a lower level of specialty fees Lower Mortgage, Specialty Income Partly Offset by Higher Service Fees Noninterest income totaled $82.4 million, down $1.3 million, or 2% linked-quarter Service charges and bank card & ATM fees up primarily due to increased activity, although lower than pre-pandemic levels Secondary mortgage fees continue to be impacted by the favorable rate environment, albeit a lower level of refinance activity compared to previous quarters Other income decrease related to lower levels of specialty income (BOLI) in 4Q20 partially offset by higher derivative income Expect 1Q21 fee income to be down related to anticipated lower levels of specialty income and secondary mortgage fees Secondary Mortgage Fees $11.5 14%Other $12.8 16% Noninterest Income Mix 12/31/20 $s in millions Service Charges on Deposit $19.9 24% Investment & Annuity and Insurance $5.8 7% Trust Fees $14.8 18% Bank Card & ATM Fees $17.6 21% 3Q20 NON INTEREST INCOME SERVICE CHARGES ON DEPOSIT accounts bank card & atm fees investment & annuity income and insurance trust fees secondary mortgage fees other 4q20 Non interest income Pie chart

Expenses Beat 4Q21 Guidance as Impact of Efficiency Initiatives Evident Noninterest expense totaled $182.5 million, down $12.2 million linked-quarter; operating noninterest expense totaled $183.8 million, down $7.7 million, or 4% linked-quarter 4Q21 included $1.3 million of net nonoperating items mainly from reversals of hurricane and closed branch accruals 3Q21 results include $3.2 million of net nonoperating items mostly related to Hurricane Ida Decrease in personnel expense (operating) was related to savings associated with recent efficiency initiatives A Focus on Expense Control; More Initiatives Underway Noninterest expense totaled $193.1 million, down $2.7 million, or 1% LQ Decline in personnel expense related to savings from efficiency measures taken to-date, including staff attrition and recent financial center closures Increase in other expenses mainly related to nonrecurring hurricane expense and branch closures Expense reduction initiatives to-date Closed 12 financial centers in 4Q20 8 additional financial centers closures announced in 1Q21 Ongoing branch rationalization reviews Closed Wealth Management trust offices in the NE corridor FTE down 210 compared to June 30, 2020 through staff attrition and other initiatives Early retirement package offered to select employees in 1Q21 Expect 1Q21 expenses to be flat as efficiency initiatives continue and offset typical beginning of the year increases; does not include nonrecurring charges for certain initiatives (i.e. early retirement)

Solid Capital, TCE Impacted By OCI and Excess Liquidity TCE ratio 7.71%, down 14 bps LQ Change in tangible assets -27 bps Change in OCI -16 bps Dividends -7 bps Stock buyback -6 bps Tangible net earnings +41 bps Stock Compensation and other +1 bp Repurchased 393,527 shares of common stock during 4Q21 at an average price of $48.98 per share CET1 ratio estimated at 11.16%, virtually unchanged linked-quarter Will continue to manage capital in the best interests of the Company and our shareholders; our priorities are: Organic growth Dividends Buybacks M&A Tangible Common Equity Ratio Leverage (Tier 1) Ratio CET1 Ratio and Tier 1 Risked-Based Capital Ratio Total Risk-Based Capital Ratio December 31, 2021 7.71% 8.25%(e) 11.16%(e) 12.92%(e) September 30, 2021 7.85% 8.15% 11.17% 13.06% June 30, 2021 7.70% 7.83% 10.98% 12.94% March 31, 2021 7.26% 7.89% 11.00% 13.60% December 31, 2020 7.64% 7.88% 10.61% 13.22% (e) Estimated for most recent period-end Capital Rebuild Continues After 1H20 De-Risking Activities TCE ratio 7.64%, up 11 bps LQ (7.99% excluding PPP loans) Tangible net earnings +34 bps Change in tangible assets/additional excess liquidity -10 bps Dividends -7 bps Change in OCI & other -6 bps CET1 ratio 10.70%, up 40 bps linked-quarter Intend to pay quarterly dividend in consultation with examiners; board reviews dividend policy quarterly Buybacks on hold Tangible Common Equity Ratio Leverage (Tier 1) Ratio CET1 Ratio and Tier 1 Risked-Based Capital Ratio Total Risk-Based Capital Ratio December 31, 2020 7.64% 7.87%(e) 10.70%(e) 13.31%(e) September 30, 2020 7.53% 7.70% 10.30% 12.92% June 30, 2020 7.33% 7.37% 9.78% 12.36% March 31, 2020 8.00% 8.40% 10.02% 11.87% December 31, 2019 8.45% 8.76% 10.50% 11.90% (e) Estimated for most recent period-end; effective March 31, 2020 regulatory capital ratios reflect the election to use the five-year CECL transition rules

2022 Forward Guidance 2021 Actual FY 2022 Outlook ** Core Loans (EOP) (excl PPP loans) * $20.6B (excl PPP loans) Expect 6-8% EOP core loan growth; quarterly results will reflect normal seasonality Deposits (EOP) $30.5B Expect EOP deposits to remain flat to slightly down Net Interest Margin (NIM) 2.95% (FY21) 2.80% (4Q21) Expect NIM to remain flattish to slightly down from 4Q21 until mid-year 2022 then begin to widen Reserve for Credit Losses $371.4MM or 1.76% of total loans Future assumptions in economic forecasts will drive level of reserves; continuation of modest reserve releases expected over next several quarters Noninterest Income (operating) $353.4MM Expect noninterest income to remain flattish as improvement in most fee categories are offset by lower secondary mortgage fees Noninterest Expense (operating) $760.1MM Expect operating expense to be down approximately 2% from FY21 Effective Tax Rate 18.5% 19%-20% Efficiency Ratio 57.29% (FY21) 56.57% (4Q21) 55% by 4Q22 3-Year Corporate Strategic Objectives (CSOs) to be achieved by 4Q24 ** 2021 Actual 2021 Actual excluding nonoperating items, PPP and negative PLLL Objective ROA 1.32% 1.12% 1.35% - 1.45% TCE 7.71% NA > 8% ROTCE 17.74% 14.39% > 15% Efficiency Ratio 57.29% 60.62% ≤ 55% * See slide 9 for details on PPP loans ** 2022 guidance and 3 year CSOs do not include rate increases

Efficiency ratio target of 55% to be achieved by 4Q22 Successfully implemented efficiency initiatives during 2021 Thoughtful execution of revenue and efficiency strategies will continue into 2022: Continued momentum in core loan growth at a mid-single digit LQA level throughout 2022 Maintain our focus on expense management in 2022 Additional efficiency initiatives (e.g. strategic procurement) will support the strategy of cost reductions to offset items like assumed wage inflation and new banker hires Deployment of excess liquidity into loans and then reinvestment in the bond portfolio Expense Catalyst: successful execution of efficiency efforts Path to 55% Efficiency Ratio Revenue Catalyst: new banker hires 15 new bankers were added in growth or new markets across the footprint, in 2H21, including middle market, commercial and healthcare, with more planned for 2022 ER Progress to-date 1Q20A 4Q21A Change Branches 215 177 -38 FTE 4,148 3,486 -662 Operating Expense $203.3 million $183.8 million ($19.5) million or -10% Efficiency Ratio 62.1% 56.6% -550 bps Dallas, TX +6 San Antonio, TX +2 Houston, TX +1 Beaumont, TX +1 Nashville, TN +2 Tampa, FL +3

Strategic Plan Designed To Provide Meaningful Shareholder Returns Updated CSOs Recover value and establish forward momentum Employer of Choice Path to 55% Efficiency Ratio Expense focus continues in order to fund revenue enhancements Revenue enhancements are the main driver in achieving goal by 4Q22 Leverage current infrastructure for growth Regain pre-pandemic pace Demonstrate ability to manage any perceived credit overhang Attract, develop, retain top talent (i.e., new banker hires in growth markets) Remain source of strength for clients, associates, and communities ESG will remain an important part of our corporate strategy

Appendix and Non-GAAP Reconciliations Appendix and Non-GAAP Reconciliations CHANCOCK WHITNEY

Summary Income Statement ($ in millions, except for share data) *Non-GAAP measure: see slide 27 for non-GAAP reconciliation       Change       Change 4Q21 3Q21 4Q20 LQ Prior Year   YTD 2021 YTD 2020 Y-o-Y 231.9 237.5 241.4 (5.6) (9.5) Net Interest Income (TE) 944.4 955.5 (11.1) (28.4) (27.0) 24.2 (1.4) (52.6) Provision for Credit Losses (77.5) 602.9 (680.4)                   89.6 93.4 82.4 (3.8) 7.2 Noninterest Income 364.3 324.4 39.9 182.5 194.7 193.1 (12.2) (10.6) Noninterest Expense 807.0 788.8 18.2                   164.8 160.3 103.3 4.5 61.5 Income (loss) before Income Tax 568.1 (124.7) 692.9 27.1 30.7 (0.3) (3.6) 27.4 Income Tax Expense (Benefit) 104.8 (79.6) 184.4 137.7 129.6 103.6 8.1 34.1 Net Income (loss) 463.2 (45.2) 508.4 134.2 134.8 130.6 (0.6) 3.6 Operating PPNR (TE)* 537.6 491.2 46.4                   137.7 129.6 103.6 8.2 34.1 Net Income (loss) 463.2 (45.1) 508.4 (2.5) (2.4) (2.1) (0.1) (0.4) Net Income or dividends allocated to participating securities (9.1) (1.8) (7.3) 135.2 127.2 101.5 8.0 33.7 Net Income (loss) available to common shareholders 454.1 (46.9) 501.1 87.1 87.0 86.7 0.1 0.4 Weighted average common shares - diluted 87.0 86.5 0.5 1.55 1.46 1.17 0.09 0.38 Reported EPS 5.22 (0.54) 5.76                   2.80% 2.94% 3.22% -14 bps -42 bps NIM 2.95% 3.27% -32 bps 1.53% 1.46% 1.25% 7 bps 28 bps ROA 1.32% -0.14% 146 bps 15.00% 14.26% 12.10% 74 bps 290 bps ROE 13.07% -1.32% 1439 bps 56.57% 57.44% 58.23% -87 bps -166 bps Efficiency Ratio 57.29% 60.07% -278 bps

Summary Balance Sheet ($ in millions) 4Q21 includes $0.5 billion, 3Q21 includes $0.9 billion and 4Q20 includes $2.0 billion in PPP loans, net 4Q21 includes $0.7 billion, 3Q21 includes $1.2 billion and 4Q20 includes $2.2 billion in average PPP loans, net Average securities excludes unrealized gain/(loss) Summary Balance Sheet ($ in millions) 4Q20 and YTD 2020 include $2.0 billion and 3Q20 included $2.3 billion in PPP loans, net Average securities excludes unrealized gain /(loss)       Change       Change 4Q20 3Q20 4Q19 LQ PY Line Item YTD 2020 YTD 2019 Y-o-Y           EOP Balance Sheet       $21,789.9 $22,240.2 $21,212.8 ($450.3) $577.1 Loans (1) $21,789.9 $21,212.8 $577.1 7,356.5 7,056.3 6,243.3 300.2 1,113.2 Securities 7,356.5 6,243.3 1,113.2 30,616.3 30,179.1 27,622.2 437.2 2,994.1 Earning Assets 30,616.3 27,622.2 2,994.1 33,638.6 33,193.3 30,600.8 445.3 3,037.8 Total assets 33,638.6 30,600.8 3,037.8                   $27,698.0 $27,030.7 $23,803.6 $667.3 $3,894.4 Deposits $27,698.0 $23,803.6 $3,894.4 1,667.5 1,906.9 2,714.9 (239.4) (1,047.4) Short-term borrowings 1,667.5 2,714.9 (1,047.4) 30,199.6 29,817.7 27,133.1 381.9 3,066.5 Total Liabilities 30,199.6 27,133.1 3,066.5 3,439.0 3,375.6 3,467.7 63.4 (28.7) Stockholders' Equity 3,439.0 3,467.7 (28.7)                             Avg Balance Sheet       $22,065.7 $22,407.8 $21,037.9 ($342.1) $1,027.8 Loans $22,166.5 $20,380.0 $1,786.5 6,921.1 6,389.2 6,201.6 531.9 719.5 Securities (2) 6,398.7 5,864.2 534.5 29,875.5 29,412.3 27,441.5 463.2 2,434.0 Average earning assets 29,235.3 26,476.9 2,758.4 33,067.5 32,685.4 30,343.3 382.1 2,724.2 Total assets 32,391.0 29,125.4 3,265.6                   $27,040.4 $26,763.8 $23,848.4 $276.6 $3,192.0 Deposits $26,212.3 $23,299.3 $2,913.0 1,779.5 1,733.3 2,393.4 46.2 (613.9) Short-term borrowings 1,978.2 1,942.1 36.1 29,660.8 29,333.8 26,869.6 327.0 2,791.2 Total Liabilities 28,957.9 25,822.8 3,135.1 3,406.6 3,351.6 3,473.7 55.0 (67.1) Stockholders' Equity 3,433.1 3,302.7 130.4 3.99% 3.95% 4.69% 4 bps -70 bps Loan Yield 4.13% 4.81% -68 bps 2.23% 2.31% 2.56% -8 bps -33 bps Securities Yield 2.38% 2.62% -24 bps 0.31% 0.39% 1.11% -8 bps -80 bps Cost of IB Deposits 0.57% 1.25% -68 bps 79% 82% 89% -361 bps -1045 bps Loan/Deposit Ratio (Period End) 79% 89% -1045 bps CHANCOCK WHITNEY 26       Change       Change 4Q21 3Q21 4Q20 LQ Prior Year   YTD 2021 YTD 2020 Y-o-Y           EOP Balance Sheet       21,134.3 20,886.0 21,789.9 248.3 (655.6) Loans (1) 21,134.3 21,789.9 (655.6) 8,552.4 8,308.6 7,356.5 243.8 1,195.9 Securities 8,552.4 7,356.5 1,195.9 33,610.4 32,348.0 30,616.3 1,262.4 2,994.1 Earning Assets 33,610.4 30,616.3 2,994.1 36,531.2 35,318.3 33,638.6 1,212.9 2,892.6 Total assets 36,531.2 33,638.6 2,892.6                   30,465.9 29,208.1 27,697.9 1,257.8 2,768.0 Deposits 30,465.9 27,697.9 2,768.0 1,665.1 1,745.2 1,667.5 (80.1) (2.4) Short-term borrowings 1,665.1 1,667.5 (2.4) 32,860.9 31,688.5 30,199.6 1,172.4 2,661.3 Total Liabilities 32,860.9 30,199.6 2,661.3 3,670.4 3,629.8 3,439.0 40.6 231.4 Stockholders' Equity 3,670.4 3,439.0 231.4                             Avg Balance Sheet       20,770.1 20,941.2 22,065.7 (171.1) (1,295.6) Loans (2) 21,207.9 22,166.5 (958.6) 8,378.3 8,368.8 6,921.1 9.5 1,457.2 Securities (3) 8,105.8 6,398.7 1,707.1 32,913.7 32,097.4 29,875.5 816.3 3,038.2 Average earning assets 32,060.9 29,235.3 2,825.6 35,829.0 35,208.0 33,067.5 621.0 2,761.5 Total assets 35,075.4 32,391.0 2,684.4                   29,750.7 29,237.3 27,040.4 513.4 2,710.3 Deposits 29,093.7 26,212.3 2,881.4 1,691.6 1,612.3 1,779.5 79.3 (87.9) Short-term borrowings 1,663.2 1,978.2 (315.0) 32,187.0 31,601.9 29,660.8 585.1 2,526.2 Total Liabilities 31,530.1 28,957.9 2,572.2 3,642.0 3,606.1 3,406.6 35.9 235.4 Stockholders' Equity 3,545.3 3,433.1 112.2                   3.83% 3.90% 3.99% -7 bps -16 bps Loan Yield 3.92% 4.13% -21 bps 1.86% 1.91% 2.23% -5 bps -37 bps Securities Yield 1.92% 2.38% -46 bps 0.12% 0.13% 0.31% -1 bp -19 bps Cost of IB Deposits 0.17% 0.57% -40 bps 69.37% 71.51% 78.67% -214 bps -930 bps Loan/Deposit Ratio 69.37% 78.67% -930 bps

Results *Non-GAAP measures: see slide 27 for non-GAAP reconciliation   4Q20 1Q21 2Q21 3Q21 4Q21 Operating PPNR (TE)* ($000) 130,607 131,526 137,176 134,784 134,152 Net Interest Income (TE) ($000) 241,401 237,509 237,498 237,477 231,931 Net Interest Margin (TE) 3.22% 3.09% 2.96% 2.94% 2.80% Operating Noninterest Income* ($000) 82,350 87,089 91,472 88,785 86,012 Operating Expense* ($000) 193,144 193,072 191,793 191,477 183,791 Efficiency Ratio 58.23% 58.12% 57.01% 57.44% 56.57% Results *Non-GAAP measures. See slides 29-31 for non-GAAP reconciliations   4Q19 1Q20 2Q20 3Q20 4Q20 Operating PPNR (TE)* ($000) 125,660 115,688 118,518 126,346 130,607 Net Interest Income (TE)* ($000) 236,736 234,636 241,114 238,372 241,401 Net Interest Margin (TE)* 3.43% 3.41% 3.23% 3.23% 3.22% Noninterest Income ($000) 82,924 84,387 73,943 83,748 82,350 Operating Expense* ($000) 194,000 203,335 196,539 195,774 193,144 Efficiency Ratio* 58.88% 62.06% 60.74% 59.29% 58.23% CHANCOCK WHITNEY 27

Balance Sheet Summary   4Q20 1Q21 2Q21 3Q21 4Q21 Average Loans ($MM) 22,066 21,745 21,389 20,941 20,770 Average Total Securities ($MM) 6,921 7,469 8,195 8,369 8,378 Average Deposits ($MM) 27,040 28,139 29,229 29,237 29,751 Loan Yield (TE) 3.99% 4.01% 3.95% 3.90% 3.83% Cost of Deposits 0.18% 0.13% 0.10% 0.07% 0.06% Tangible Common Equity Ratio 7.64% 7.26% 7.70% 7.85% 7.71% Balance Sheet Summary   4Q19 1Q20 2Q20 3Q20 4Q20 Average Loans ($MM) 21,038 21,234 22,957 22,408 22,066 Average Total Securities ($MM) 6,202 6,149 6,130 6,389 6,921 Average Deposits ($MM) 23,848 24,327 26,703 26,764 27,040 Loan Yield (TE) 4.69% 4.56% 4.04% 3.95% 3.99% Cost of Interest Bearing Deposits 1.11% 1.01% 0.58% 0.39% 0.31% Tangible Common Equity Ratio 8.45% 8.00% 7.33% 7.53% 7.64% CHANCOCK WHITNEY 28

Operating Revenue (TE), Operating PPNR (TE) Reconciliations   Three Months Ended (in thousands) 12/31/2021 9/30/2021 6/30/2021 3/31/2021 12/31/2020 Net interest income $229,296 $234,709 $234,643 $234,587 $238,286 Noninterest income 89,612 93,361 94,272 87,089 82,350 Total revenue $318,908 $328,070 $328,915 $321,676 $320,636 Taxable equivalent adjustment 2,635 2,768 2,854 2,922 3,115 Nonoperating revenue (3,600) (4,576) (2,800) — — Operating revenue (TE) $317,943 $326,262 $328,969 $324,598 $323,751 Noninterest expense (182,462) (194,703) (236,770) (193,072) (193,144) Nonoperating expense (1,329) 3,225 44,977 — — Operating expense (183,791) (191,478) (191,793) (193,072) (193,144) Operating pre-provision net revenue (TE) $134,152 $134,784 $137,176 $131,526 $130,607 Total Revenue (TE), Operating PPNR (TE) Reconciliations Taxable equivalent (TE) amounts are calculated using a federal income tax rate of 21%.   Three Months Ended (in thousands) 12/31/2020 9/30/2020 6/30/2020 3/31/2020 12/31/2019 Net interest income $238,286 $235,183 $237,866 $231,188 $233,156 Noninterest income 82,350 83,748 73,943 84,387 82,924 Total revenue $320,636 $318,931 $311,809 $315,575 $316,080 Taxable equivalent adjustment 3,115 3,189 3,248 3,448 3,580 Total revenue (TE) $323,751 $322,120 $315,057 $319,023 $319,660 Noninterest expense (193,144) (195,774) (196,539) (203,335) (197,856) Nonoperating expense — — — — 3,856 Operating pre-provision net revenue $130,607 $126,346 $118,518 $115,688 $125,660 CHANCOCK WHITNEY 31 Taxable equivalent (TE) amounts are calculated using a federal tax rate of 21% (in thousands) 4Q21 3Q21 2Q21 Nonoperating Income       Gain from hurricane-related insurance settlement $3,600 $ -— $ -— Gain on sale of Hancock Horizon Funds -— 4,576 -— Gain on sale of Mastercard Class B common stock -— -— 2,800 Nonoperating Expense       Efficiency initiatives (649) (1,867) 40,812 Hurricane related expenses (680) 5,092 -— Loss on redemption of subordinated debentures -— -— 4,165 Total Nonoperating (income)/expense items, net ($4,929) ($1,351) $42,177 Nonoperating Items

Commercial Loans (C&I, CRE, C&D)* *Excludes $0.9 billion in PPP loans As of December 31, 2021 HNCOCK WHITNEY 10 Total Commercial Loans Outstanding % of Total Loans Commitment ($s in millions) Real Estate, Rental and Leasing $3,347 16.2% $4,827 Health Care and Social Assistance 1,889 9.2% 2,346 Retail Trade 1,852 9.0% 2,301 Construction 1,136 5.5% 2,093 Hospitality 1,033 5.0% 1,168 Manufacturing 936 4.5% 1,543 Finance and Insurance 903 4.4% 1,567 Wholesale Trade 845 4.1% 1,479 Transportation and Warehousing 804 3.9% 1,083 Professional, Scientific, and Technical Services 637 3.1% 1,044 Public Administration 597 2.9% 620 Other Services (except Public Administration) 468 2.3% 587 Educational Services 293 1.4% 438 Energy 267 1.3% 433 Administrative and Support and Waste Mgmt and Remediation Services 240 1.2% 375 Other (less than 1% individually) 1,349 6.5% 2,664 Grand Total $16,596 80.6% $24,568 *Excludes $531 million in PPP loans

Current Hedge Positions Cash Flow (CF) Hedges Current net receive on notional CF hedges is approximately 1.42% on $1.1 billion or approximately $16 million annualized with no rate changes $500 million of CF hedges terminated in 3Q21 will provide NII support of $19.2 million in 2022 and 2023 collectively No additional CF hedges were terminated in 4Q21 Total Termination Value on remaining active CF Hedges is approximately $2.8 million as of 12/31/21 Termination locks in current economic value but removes protection of the hedge, therefore increasing asset sensitivity $475 million of existing CF hedges will mature over the course of 2022 Fair Value (FV) Hedges $2.1 billion in securities are hedged with $1.8 billion of FV hedges Duration (Market Price Risk) reduced from approximately 7.7 to 3.5 on hedged securities Current Termination Value of FV hedges is approximately $11.5 million at 12/31/2021 FV hedges become fully effective beginning June 2023 through August 2025; at that point we pay fixed 1.32% and receive the fed fund effective rate (resulting in these bonds being a variable rate of FF plus 33 bps)

Fourth Quarter 2021 Earnings Conference Call 1/18/2022 HANCOCK WHITNEY