MILLENNIUM MANAGEMENT LLC

Position in IOVA — Iovance Biotherapeutics, Inc.

CIK 1273087 NEW YORK, NY

Back to IOVA Full portfolio

Position in IOVA

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$35,467,823

+$2,423,659 QoQ

Shares Held

8,525,919

-9.4% QoQ

Ownership

1.88%

of shares outstanding

% of Portfolio

0.03%

of 13F equity value

Holder Rank

of 292 holders

Holding Since

Mar 2020

25 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in IOVA Over Time

Shares Held

Position Value (USD)

Derivatives in IOVA

reported options exposure · as of Dec 31, 2025

CallValue

$642,915

CallShares

235,500

PutValue

$450,450

PutShares

165,000

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

MILLENNIUM MANAGEMENT LLC holds $4,596,585,112 across 322 Biotechnology names. IOVA ranks #30 (0.8% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	468,410	$232,673,299
2	INSM	INSMED Inc	2,048,005	$218,358,293
3	APGE	Apogee Therapeutics, Inc.	1,491,404	$197,954,052
4	JAZZ	Jazz Pharmaceuticals plc	763,880	$184,072,163
5	ONC	BeOne Medicines Ltd.	543,323	$154,830,755
6	AXSM	Axsome Therapeutics, Inc.	556,088	$136,113,659
7	BMRN	Biomarin Pharmaceutical Inc	2,071,816	$118,549,311
8	REGN	Regeneron Pharmaceuticals, Inc.	165,120	$102,958,924

All Filings in IOVA

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40 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$35,467,823	8,525,919	-9.4%	Shares	Sole	2026-08-14
2026-03-31	$33,044,164	9,414,292	+43.0%	Shares	Sole	2026-05-15
2025-12-31	$642,915	235,500	+135.5%	Call	Sole	2026-02-17
2025-12-31	$450,450	165,000	+59.1%	Put	Sole	2026-02-17
2025-12-31	$17,978,502	6,585,532	+49.2%	Shares	Sole	2026-02-17
2025-09-30	$9,577,188	4,413,451	-52.7%	Shares	Sole	2025-11-14
2025-06-30	$16,047,983	9,330,223	+5793.2%	Shares	Sole	2025-08-14
2025-03-31	$527,215	158,323	+109.7%	Shares	Sole	2025-05-15
2025-03-31	$333,000	100,000	+100.0%	Call	Sole	2025-05-15
2024-12-31	$558,655	75,494	-50.0%	Shares	Sole	2025-02-14
2024-09-30	$1,417,317	150,939	-9.2%	Shares	Sole	2024-11-14
2024-06-30	$401,000	50,000	-3.7%	Call	Sole	2024-08-14
2024-06-30	$1,332,514	166,149	-89.7%	Shares	Sole	2024-08-14
2024-03-31	$23,961,880	1,616,861	+72.1%	Shares	Sole	2024-05-15
2023-12-31	$7,638,508	939,546	-88.0%	Shares	Sole	2024-02-14
2023-12-31	$421,947	51,900	-3.4%	Call	Sole	2024-02-14
2023-09-30	$244,335	53,700	-83.3%	Call	Sole	2023-11-14
2023-09-30	$35,581,336	7,820,074	+118.4%	Shares	Sole	2023-11-14
2023-09-30	$471,835	103,700	-65.8%	Put	Sole	2023-11-14
2023-06-30	$25,207,902	3,580,668	+4.9%	Shares	Sole	2023-08-14
2023-03-31	$20,850,979	3,412,599	+188.3%	Shares	Sole	2023-05-15
2022-12-31	$7,562,814	1,183,539	-3.1%	Shares	Sole	2023-02-14
2022-09-30	$11,696,844	1,220,965	-13.5%	Shares	Sole	2022-11-14
2022-06-30	$3,346,224	303,100	+2931.0%	Put	Sole	2022-08-15
2022-06-30	$15,579,504	1,411,187	-40.5%	Shares	Sole	2022-08-15
2022-06-30	$3,552,672	321,800	+197.7%	Call	Sole	2022-08-15
2022-03-31	$39,500,576	2,372,407	+618.3%	Shares	Sole	2022-05-16
2022-03-31	$1,799,865	108,100	+440.5%	Call	Sole	2022-05-16
2021-12-31	$6,305,255	330,291	-43.1%	Shares	Sole	2022-02-14
2021-06-30	$520,400	20,000	-85.7%	Call	Sole	2021-08-16
2021-03-31	$4,432,400	140,000	+55.6%	Call	Sole	2021-05-17
2021-03-31	$18,393,731	580,977	+227.4%	Shares	Sole	2021-05-17
2021-03-31	$316,600	10,000	0.0%	Put	Sole	2021-05-17
2020-12-31	$4,176,000	90,000	-18.2%	Call	Sole	2021-02-16
2020-12-31	$8,232,659	177,428	-78.1%	Shares	Sole	2021-02-16
2020-09-30	$26,719,353	811,645	+38.2%	Shares	Sole	2020-11-16
2020-09-30	$3,621,200	110,000	—	Call	Sole	2020-11-16
2020-06-30	$16,127,122	587,509	+272.0%	Shares	Sole	2020-08-14
2020-03-31	$299,400	10,000	—	Put	Sole	2020-05-14
2020-03-31	$4,728,424	157,930	—	Shares	Sole	2020-05-14
No filing history on record for this holder in this stock.