JANE STREET GROUP, LLC

Position in IOVA — Iovance Biotherapeutics, Inc.

CIK 1595888 NEW YORK, NY

Back to IOVA Full portfolio

Position in IOVA

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$18,278,427

+$3,628,089 QoQ

Shares Held

4,393,853

+5.3% QoQ

Ownership

0.970%

of shares outstanding

% of Portfolio

0.01%

of 13F equity value

Holder Rank

#16

of 292 holders

Holding Since

Mar 2020

26 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in IOVA Over Time

Shares Held

Position Value (USD)

Derivatives in IOVA

reported options exposure · as of Jun 30, 2026

CallValue

$3,037,216

CallShares

730,100

PutValue

$1,436,032

PutShares

345,200

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

JANE STREET GROUP, LLC holds $1,364,050,815 across 292 Biotechnology names. IOVA ranks #16 (1.3% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	BBIO	BridgeBio Pharma, Inc.	2,934,193	$218,538,693
2	MDGL	Madrigal Pharmaceuticals, Inc.	191,541	$102,847,939
3	AXSM	Axsome Therapeutics, Inc.	403,995	$98,885,855
4	TGTX	Tg Therapeutics, Inc.	1,752,646	$96,290,370
5	EXEL	Exelixis, Inc.	1,402,438	$76,306,651
6	QURE	uniQure N.V.	1,610,483	$74,178,846
7	HALO	Halozyme Therapeutics, Inc.	694,684	$54,372,915
8	TVTX	Travere Therapeutics, Inc.	938,699	$53,327,489

All Filings in IOVA

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50 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$1,436,032	345,200	+51.9%	Put	Defined	2026-08-14
2026-06-30	$18,278,427	4,393,853	+5.3%	Shares	Defined	2026-08-14
2026-06-30	$3,037,216	730,100	+161.6%	Call	Defined	2026-08-14
2026-03-31	$979,641	279,100	+113.7%	Call	Defined	2026-05-12
2026-03-31	$797,823	227,300	+85.1%	Put	Defined	2026-05-12
2026-03-31	$14,650,338	4,173,886	+16.5%	Shares	Defined	2026-05-12
2025-12-31	$356,538	130,600	+27.7%	Call	Defined	2026-02-12
2025-12-31	$9,783,800	3,583,810	+153.5%	Shares	Defined	2026-02-12
2025-12-31	$335,244	122,800	+79.3%	Put	Defined	2026-02-12
2025-09-30	$3,067,645	1,413,662	-29.6%	Shares	Defined	2025-11-14
2025-09-30	$148,645	68,500	+3.3%	Put	Defined	2025-11-14
2025-09-30	$221,991	102,300	-57.5%	Call	Defined	2025-11-14
2025-06-30	$114,036	66,300	+10.0%	Put	Defined	2025-08-14
2025-06-30	$413,832	240,600	+33.1%	Call	Defined	2025-08-14
2025-06-30	$3,453,022	2,007,571	+1557.9%	Shares	Defined	2025-08-14
2025-03-31	$602,064	180,800	+22.0%	Call	Defined	2025-05-19
2025-03-31	$200,799	60,300	-74.4%	Put	Defined	2025-05-19
2025-03-31	$403,229	121,090	-59.0%	Shares	Defined	2025-05-19
2024-12-31	$1,744,920	235,800	+65.9%	Put	Defined	2025-02-14
2024-12-31	$1,096,680	148,200	-92.6%	Call	Defined	2025-02-14
2024-12-31	$2,184,686	295,228	+152.4%	Shares	Defined	2025-02-14
2024-09-30	$1,098,348	116,970	-88.6%	Shares	Defined	2024-11-15
2024-09-30	$1,334,319	142,100	+94.1%	Put	Defined	2024-11-15
2024-09-30	$18,683,283	1,989,700	+928.8%	Call	Defined	2024-11-15
2024-06-30	$8,263,101	1,030,312	+0.9%	Shares	Defined	2024-08-15
2024-03-31	$15,132,212	1,021,067	+95.4%	Shares	Defined	2024-05-16
2023-12-31	$4,248,418	522,561	-5.0%	Shares	Defined	2024-02-15
2023-09-30	$2,502,112	549,915	+36.7%	Shares	Defined	2023-11-15
2023-06-30	$2,832,311	402,317	+512.5%	Shares	Defined	2023-08-14
2023-03-31	$401,328	65,684	-35.6%	Shares	Defined	2023-05-16
2022-12-31	$651,262	101,919	+67.6%	Shares	Defined	2023-02-15
2022-09-30	$582,636	60,818	-53.3%	Shares	Defined	2022-11-15
2022-06-30	$1,436,491	130,117	-58.2%	Shares	Defined	2022-08-16
2022-03-31	$1,218,780	73,200	+3.2%	Put	Defined	2022-05-17
2022-03-31	$3,220,110	193,400	+62.4%	Call	Defined	2022-05-17
2022-03-31	$5,183,477	311,320	+83.5%	Shares	Defined	2022-05-17
2021-12-31	$1,353,481	70,900	-43.6%	Put	Defined	2022-02-15
2021-12-31	$2,273,619	119,100	+48.5%	Call	Defined	2022-02-15
2021-12-31	$3,237,986	169,617	+51.1%	Shares	Defined	2022-02-15
2021-09-30	$3,097,296	125,600	-53.2%	Put	Defined	2021-11-16
2021-09-30	$1,977,732	80,200	-51.9%	Call	Defined	2021-11-16
2021-09-30	$2,767,690	112,234	-15.0%	Shares	Defined	2021-11-16
2021-06-30	$3,434,535	131,996	+58.3%	Shares	Defined	2021-08-16
2021-06-30	$6,986,370	268,500	+731.3%	Put	Defined	2021-08-16
2021-06-30	$4,337,534	166,700	+239.5%	Call	Defined	2021-08-16
2021-03-31	$1,022,618	32,300	—	Put	Defined	2021-05-18
2021-03-31	$1,554,506	49,100	-59.9%	Call	Defined	2021-05-18
2021-03-31	$2,640,032	83,387	-19.1%	Shares	Defined	2021-05-18
2020-12-31	$4,785,556	103,137	—	Shares	Defined	2021-02-17
2020-12-31	$5,674,720	122,300	—	Call	Defined	2021-02-17
No filing history on record for this holder in this stock.