JANE STREET GROUP, LLC

Position in IOVA — Iovance Biotherapeutics, Inc.

CIK 1595888 NEW YORK, NY

Back to IOVA Full portfolio

Position in IOVA

as of Mar 31, 2026 · filed May 12, 2026 Compact

Position Value

$14,650,338

+$4,866,538 QoQ

Shares Held

4,173,886

+16.5% QoQ

Ownership

0.935%

of shares outstanding

% of Portfolio

0.02%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

25 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Common Shares in IOVA Over Time

Shares Held

Position Value (USD)

Derivatives in IOVA

reported options exposure · as of Mar 31, 2026

CallValue

$979,641

CallShares

279,100

PutValue

$797,823

PutShares

227,300

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

JANE STREET GROUP, LLC holds $1,255,284,514 across 317 Biotechnology names. IOVA ranks #21 (1.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	BBIO	BridgeBio Pharma, Inc.	1,757,672	$130,524,721
2	RPRX	Royalty Pharma plc	2,400,382	$115,146,324
3	TGTX	Tg Therapeutics, Inc.	2,041,669	$67,824,242
4	VRTX	Vertex Pharmaceuticals Inc / Ma	122,946	$54,900,305
5	HALO	Halozyme Therapeutics, Inc.	831,707	$53,753,223
6	EXEL	Exelixis, Inc.	1,087,030	$46,622,715
7	JAZZ	Jazz Pharmaceuticals plc	223,615	$42,274,415
8	BNTX	BioNTech SE	336,757	$29,930,962

All Filings in IOVA

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50 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$979,641	279,100	+22.8%	Call	Defined	2026-05-12
2026-03-31	$797,823	227,300	-94.6%	Put	Defined	2026-05-12
2026-03-31	$14,650,338	4,173,886	+3095.9%	Shares	Defined	2026-05-12
2025-12-31	$356,538	130,600	-96.4%	Call	Defined	2026-02-12
2025-12-31	$9,783,800	3,583,810	+2818.4%	Shares	Defined	2026-02-12
2025-12-31	$335,244	122,800	-91.3%	Put	Defined	2026-02-12
2025-09-30	$3,067,645	1,413,662	+1963.7%	Shares	Defined	2025-11-14
2025-09-30	$148,645	68,500	-33.0%	Put	Defined	2025-11-14
2025-09-30	$221,991	102,300	+54.3%	Call	Defined	2025-11-14
2025-06-30	$114,036	66,300	-72.4%	Put	Defined	2025-08-14
2025-06-30	$413,832	240,600	-88.0%	Call	Defined	2025-08-14
2025-06-30	$3,453,022	2,007,571	+1557.9%	Shares	Defined	2025-08-14
2025-03-31	$403,229	121,090	+100.8%	Shares	Defined	2025-05-19
2025-03-31	$200,799	60,300	-66.6%	Put	Defined	2025-05-19
2025-03-31	$602,064	180,800	-23.3%	Call	Defined	2025-05-19
2024-12-31	$1,744,920	235,800	+59.1%	Put	Defined	2025-02-14
2024-12-31	$1,096,680	148,200	-49.8%	Call	Defined	2025-02-14
2024-12-31	$2,184,686	295,228	+152.4%	Shares	Defined	2025-02-14
2024-09-30	$1,098,348	116,970	-17.7%	Shares	Defined	2024-11-15
2024-09-30	$1,334,319	142,100	-92.9%	Put	Defined	2024-11-15
2024-09-30	$18,683,283	1,989,700	+93.1%	Call	Defined	2024-11-15
2024-06-30	$8,263,101	1,030,312	+0.9%	Shares	Defined	2024-08-15
2024-03-31	$15,132,212	1,021,067	+95.4%	Shares	Defined	2024-05-16
2023-12-31	$4,248,418	522,561	-5.0%	Shares	Defined	2024-02-15
2023-09-30	$2,502,112	549,915	+36.7%	Shares	Defined	2023-11-15
2023-06-30	$2,832,311	402,317	+512.5%	Shares	Defined	2023-08-14
2023-03-31	$401,328	65,684	-35.6%	Shares	Defined	2023-05-16
2022-12-31	$651,262	101,919	+67.6%	Shares	Defined	2023-02-15
2022-09-30	$582,636	60,818	-53.3%	Shares	Defined	2022-11-15
2022-06-30	$1,436,491	130,117	+77.8%	Shares	Defined	2022-08-16
2022-03-31	$1,218,780	73,200	-62.2%	Put	Defined	2022-05-17
2022-03-31	$3,220,110	193,400	-37.9%	Call	Defined	2022-05-17
2022-03-31	$5,183,477	311,320	+339.1%	Shares	Defined	2022-05-17
2021-12-31	$1,353,481	70,900	-40.5%	Put	Defined	2022-02-15
2021-12-31	$2,273,619	119,100	-29.8%	Call	Defined	2022-02-15
2021-12-31	$3,237,986	169,617	+35.0%	Shares	Defined	2022-02-15
2021-09-30	$3,097,296	125,600	+56.6%	Put	Defined	2021-11-16
2021-09-30	$1,977,732	80,200	-28.5%	Call	Defined	2021-11-16
2021-09-30	$2,767,690	112,234	-15.0%	Shares	Defined	2021-11-16
2021-06-30	$3,434,535	131,996	-50.8%	Shares	Defined	2021-08-16
2021-06-30	$6,986,370	268,500	+61.1%	Put	Defined	2021-08-16
2021-06-30	$4,337,534	166,700	+416.1%	Call	Defined	2021-08-16
2021-03-31	$1,022,618	32,300	-34.2%	Put	Defined	2021-05-18
2021-03-31	$1,554,506	49,100	-41.1%	Call	Defined	2021-05-18
2021-03-31	$2,640,032	83,387	-19.1%	Shares	Defined	2021-05-18
2020-12-31	$4,785,556	103,137	-15.7%	Shares	Defined	2021-02-17
2020-12-31	$5,674,720	122,300	+67.8%	Call	Defined	2021-02-17
2020-12-31	$3,382,560	72,900	+32.5%	Put	Defined	2021-02-17
2020-09-30	$1,810,600	55,000	-68.3%	Call	Defined	2020-11-17
2020-09-30	$5,711,882	173,508	—	Shares	Defined	2020-11-17
No filing history on record for this holder in this stock.