MILLENNIUM MANAGEMENT LLC
Position in MIST — Milestone Pharmaceuticals Inc.
CIK 1273087
NEW YORK, NY
Position in MIST
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$4,210,573
+$2,372,827 QoQ
Shares Held
3,142,219
+103.5% QoQ
Ownership
2.52%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#6
of 78 holders
Holding Since
Mar 2020
24 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in MIST Over Time
Shares Held
Position Value (USD)
Derivatives in MIST
reported options exposure · as of Dec 31, 2023CallValue
$394,788
CallShares
236,400
PutValue
$0
PutShares
0
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026MILLENNIUM MANAGEMENT LLC holds $4,596,705,485 across 322 Biotechnology names. MIST ranks #178 (0.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
468,410 | $232,673,299 | |
| 2 | INSM |
INSMED Inc
|
2,048,005 | $218,358,293 | |
| 3 | APGE |
Apogee Therapeutics, Inc.
|
1,491,404 | $197,954,052 | |
| 4 | JAZZ |
Jazz Pharmaceuticals plc
|
763,880 | $184,072,163 | |
| 5 | ONC |
BeOne Medicines Ltd.
|
543,323 | $154,830,755 | |
| 6 | AXSM |
Axsome Therapeutics, Inc.
|
556,088 | $136,113,659 | |
| 7 | BMRN |
Biomarin Pharmaceutical Inc
|
2,071,816 | $118,549,311 | |
| 8 | REGN |
Regeneron Pharmaceuticals, Inc.
|
165,120 | $102,958,924 |
All Filings in MIST
Export CSV
29 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $4,210,573 | 3,142,219 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $1,837,746 | 1,544,325 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $813,322 | 402,635 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $803,118 | 401,559 | Shares | Sole | 2025-11-14 | |
| 2025-03-31 | $257,665 | 322,082 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $6,379,691 | 2,703,259 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $4,223,358 | 2,778,525 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $3,629,907 | 2,749,930 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $5,111,545 | 2,855,612 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $394,788 | 236,400 | Call | Sole | 2024-02-14 | |
| 2023-12-31 | $2,495,796 | 1,494,489 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $5,255,402 | 1,695,291 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $4,990,828 | 1,751,168 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $6,812,346 | 1,729,022 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $792,000 | 200,000 | Call | Sole | 2023-02-14 | |
| 2022-12-31 | $7,900,314 | 1,995,029 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $612,054 | 66,600 | Call | Sole | 2022-11-14 | |
| 2022-09-30 | $226,074 | 24,600 | Put | Sole | 2022-11-14 | |
| 2022-09-30 | $8,575,170 | 933,098 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $8,353,926 | 1,358,362 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $8,274,885 | 1,288,923 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $6,457,428 | 985,867 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $3,969,826 | 695,241 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $3,952,465 | 718,630 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $4,156,044 | 717,797 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $4,795,766 | 715,786 | Shares | Sole | 2021-02-16 | |
| 2020-12-31 | $134,000 | 20,000 | Call | Sole | 2021-02-16 | |
| 2020-09-30 | $2,252,759 | 307,754 | Shares | Sole | 2020-11-16 | |
| 2020-03-31 | $353,018 | 191,858 | Shares | Sole | 2020-05-14 | |
| No filing history on record for this holder in this stock. | ||||||