D. E. Shaw & Co., Inc.

CIK

0001009207

City

New York

State / Country

Stock

PBYI — PUMA BIOTECHNOLOGY, INC.

Holdings in PBYI

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2025-12-31	$2,250,861	378,296	-24.1%	Shares	Defined	2026-02-17
2025-09-30	$2,647,555	498,598	-22.2%	Shares	Defined	2025-11-14
2025-06-30	$2,197,875	640,780	+12.1%	Shares	Defined	2025-08-14
2025-03-31	$1,692,128	571,665	+156.8%	Shares	Defined	2025-05-15
2024-12-31	$678,954	222,608	+287.9%	Shares	Defined	2025-02-14
2024-09-30	$146,339	57,388	-56.6%	Shares	Defined	2024-11-14
2022-12-31	$559,138	132,184	-75.5%	Shares	Defined	2023-02-14
2022-09-30	$1,276,349	538,544	-43.9%	Shares	Defined	2022-11-14
2022-06-30	$2,736,205	960,072	-4.6%	Shares	Defined	2022-08-15
2022-03-31	$2,897,231	1,005,983	+36.7%	Shares	Defined	2022-05-16
2021-12-31	$2,237,324	735,962	+1364.0%	Shares	Defined	2022-02-14
2021-09-30	$352,406	50,272	-54.9%	Shares	Defined	2021-11-15
2021-06-30	$1,023,625	111,506	+39.0%	Shares	Defined	2021-08-16
2021-03-31	$779,505	80,196	+130.4%	Shares	Defined	2021-05-17
2020-12-31	$357,140	34,809	+23.0%	Shares	Defined	2021-02-16
2020-12-31	$290,358	28,300	0.0%	Shares	Defined	2021-02-16
2020-09-30	$285,547	28,300	-6.3%	Shares	Defined	2020-11-16
2020-09-30	$304,889	30,217	-84.1%	Shares	Defined	2020-11-16
2020-06-30	$1,981,814	190,011	+571.4%	Shares	Defined	2020-08-14
2020-06-30	$295,169	28,300	-81.9%	Shares	Defined	2020-08-14
2020-03-31	$1,317,424	156,093	+451.6%	Shares	Defined	2020-05-15
2020-03-31	$238,852	28,300	—	Shares	Defined	2020-05-15