TWO SIGMA ADVISERS, LP

CIK

1478735

City

NEW YORK

State / Country

Stock

SGMO — Sangamo Therapeutics, Inc

Top Portfolio Positions

2,276 positions · $51,226,514,524 total · as of Dec 31, 2025

Ticker	Company	Shares	Value (USD)	% of Portfolio
NVDA	Nvidia Corp Technology	8,951,900	$1,669,529,350	3.26%
AAPL	Apple Inc. Technology	5,896,700	$1,603,076,862	3.13%
MSFT	Microsoft Corp Technology	2,673,180	$1,292,803,311	2.52%
AMZN	Amazon Com Inc Consumer Cyclical	4,979,120	$1,149,280,478	2.24%
JPM	Jpmorgan Chase & Co Financial Services	2,204,020	$710,179,324	1.39%
MA	Mastercard Inc Financial Services	1,227,980	$701,029,222	1.37%
MU	Micron Technology Inc Technology	2,331,800	$665,519,038	1.30%
PLTR	Palantir Technologies Inc. Technology	3,674,200	$653,089,050	1.27%
SCHW	Schwab Charles Corp Financial Services	6,283,895	$627,823,949	1.23%
TSLA	Tesla, Inc. Consumer Cyclical	1,389,973	$625,098,657	1.22%

43 quarters · across all stocks

Compact Export CSV

23 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2025-12-31	$1,824,167	4,343,255	+106.0%	Shares	Sole	2026-02-17
2025-09-30	$1,412,597	2,108,355	+74.7%	Shares	Sole	2025-11-14
2025-06-30	$651,636	1,206,734	+34.2%	Shares	Sole	2025-08-14
2025-03-31	$593,508	899,255	+27.1%	Shares	Sole	2025-05-15
2024-12-31	$721,706	707,555	-13.8%	Shares	Sole	2025-02-14
2024-06-30	$295,327	820,355	-42.6%	Shares	Sole	2024-08-14
2024-03-31	$956,930	1,428,255	-31.5%	Shares	Sole	2024-05-15
2023-12-31	$1,126,037	2,085,255	+147.4%	Shares	Sole	2024-02-14
2023-09-30	$505,773	842,955	-16.6%	Shares	Sole	2023-11-14
2023-06-30	$1,314,111	1,010,855	-5.8%	Shares	Sole	2023-08-14
2023-03-31	$1,889,632	1,073,655	-10.1%	Shares	Sole	2023-05-15
2022-12-31	$3,748,390	1,193,755	+10.1%	Shares	Sole	2023-02-14
2022-09-30	$5,314,809	1,084,655	+85.2%	Shares	Sole	2022-11-14
2022-06-30	$2,425,025	585,755	+3.3%	Shares	Sole	2022-08-15
2022-03-31	$3,293,427	566,855	-26.9%	Shares	Sole	2022-05-16
2021-12-31	$5,817,412	775,655	-19.4%	Shares	Sole	2022-02-14
2021-09-30	$8,668,115	962,055	-6.0%	Shares	Sole	2021-11-15
2021-06-30	$12,247,165	1,023,155	-27.2%	Shares	Sole	2021-08-16
2021-03-31	$17,609,098	1,405,355	-0.6%	Shares	Sole	2021-05-17
2020-12-31	$22,067,154	1,413,655	+3.7%	Shares	Sole	2021-02-16
2020-09-30	$12,888,429	1,363,855	+23.7%	Shares	Sole	2020-11-16
2020-06-30	$9,879,788	1,102,655	+266.8%	Shares	Sole	2020-09-15
2020-03-31	$1,915,172	300,655	—	Shares	Sole	2020-05-15
No 13F history on record for this holder in this stock.