Stocks
VRTX
ROYAL BANK OF CANADA

ROYAL BANK OF CANADA

CIK

0001000275

City

TORONTO

State / Country

Stock

VRTX — VERTEX PHARMACEUTICALS INC / MA

Holdings in VRTX

Position Over Time

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2025-12-31	$391,591,055	863,753	+763.8%	Shares	Defined	2026-02-17
2025-12-31	$45,336,000	100,000	+0.6%	Shares	Sole	2026-02-17
2025-09-30	$38,943,114	99,436	+534.5%	Shares	Defined	2025-11-14
2025-06-30	$6,977,173	15,672	-98.7%	Shares	Other	2025-11-21
2025-03-31	$585,986,413	1,208,668	-16.7%	Shares	Defined	2025-11-21
2024-12-31	$584,301,184	1,450,959	-7.4%	Shares	Defined	2025-02-14
2024-09-30	$729,076,146	1,567,636	-6.8%	Shares	Defined	2024-11-14
2024-06-30	$788,199,544	1,681,600	+336220.0%	Shares	Defined	2024-11-06
2024-03-31	$209,005	500	-100.0%	Shares	Defined	2024-11-05
2024-03-31	$631,698,378	1,511,204	+3.9%	Shares	Defined	2024-11-05
2023-12-31	$591,810,106	1,454,472	+18.2%	Shares	Defined	2024-02-14
2023-09-30	$427,788,350	1,230,196	+1.0%	Shares	Defined	2023-11-14
2023-06-30	$428,473,644	1,217,566	+8.2%	Shares	Defined	2023-08-14
2023-03-31	$354,666,733	1,125,676	+17.2%	Shares	Defined	2023-05-15
2022-12-31	$277,353,546	960,432	+4.0%	Shares	Defined	2023-02-14
2022-09-30	$267,314,904	923,240	+4.3%	Shares	Defined	2022-11-14
2022-06-30	$249,450,366	885,235	+1467.6%	Shares	Defined	2022-08-15
2022-03-31	$14,737,496	56,472	-92.0%	Shares	Defined	2022-05-16
2021-12-31	$154,532,296	703,699	-9.9%	Shares	Defined	2022-02-14
2021-09-30	$141,591,216	780,590	-27.2%	Shares	Defined	2021-11-15
2021-06-30	$216,175,783	1,072,141	+27.4%	Shares	Defined	2021-08-16
2021-03-31	$180,846,692	841,578	-4.0%	Shares	Defined	2021-07-20
2020-12-31	$207,258,121	876,949	+20.1%	Shares	Defined	2021-02-16
2020-09-30	$198,628,274	729,929	+25.1%	Shares	Defined	2020-11-16
2020-06-30	$169,360,461	583,378	+9.4%	Shares	Defined	2020-08-14
2020-03-31	$126,846,148	533,079	—	Shares	Defined	2020-06-16