Position in VRTX
as of Jun 30, 2026
· filed Aug 13, 2026
Position Value
$270,169,956
+$128,590,878 QoQ
Shares Held
543,897
+71.5% QoQ
Ownership
0.215%
of shares outstanding
% of Portfolio
0.33%
of 13F equity value
Holder Rank
#56
of 1,732 holders
Holding Since
Mar 2020
25 quarters on record
Voting authority
Sole 0%
Shared 100%
None 0%
Common Shares in VRTX Over Time
Shares Held
Position Value (USD)
Derivatives in VRTX
reported options exposure · as of Jun 30, 2026CallValue
$0
CallShares
0
PutValue
$546,403
PutShares
1,100
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026MARSHALL WACE, LLP holds $3,014,740,742 across 267 Biotechnology names. VRTX ranks #1 (9.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
This page
|
543,897 | $270,169,956 | |
| 2 | INCY |
Incyte Corp
|
1,310,154 | $148,519,056 | |
| 3 | RPRX |
Royalty Pharma plc
|
2,450,669 | $137,409,009 | |
| 4 | SYRE |
Spyre Therapeutics, Inc.
|
991,693 | $88,042,503 | |
| 5 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
259,799 | $78,207,292 | |
| 6 | TVTX |
Travere Therapeutics, Inc.
|
1,333,207 | $75,739,488 | |
| 7 | MANE |
Veradermics, Inc
|
585,560 | $71,988,746 | |
| 8 | DFTX |
Definium Therapeutics, Inc.
|
1,298,946 | $61,102,419 |
All Filings in VRTX
Export CSV
32 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $546,403 | 1,100 | Put | Other | 2026-08-13 | |
| 2026-06-30 | $270,169,956 | 543,897 | Shares | Other | 2026-08-13 | |
| 2026-03-31 | $2,009,430 | 4,500 | Put | Other | 2026-05-15 | |
| 2026-03-31 | $893,080 | 2,000 | Call | Other | 2026-05-15 | |
| 2026-03-31 | $141,579,078 | 317,058 | Shares | Other | 2026-05-15 | |
| 2025-12-31 | $544,032 | 1,200 | Call | Other | 2026-02-13 | |
| 2025-12-31 | $92,499,947 | 204,032 | Shares | Other | 2026-02-13 | |
| 2025-12-31 | $181,344 | 400 | Put | Other | 2026-02-13 | |
| 2025-09-30 | $17,970,401 | 45,885 | Shares | Other | 2025-11-13 | |
| 2025-09-30 | $313,312 | 800 | Call | Other | 2025-11-13 | |
| 2025-09-30 | $78,328 | 200 | Put | Other | 2025-11-13 | |
| 2025-06-30 | $52,088,400 | 117,000 | Shares | Other | 2025-08-13 | |
| 2025-03-31 | $66,905,160 | 138,000 | Shares | Other | 2025-05-15 | |
| 2024-12-31 | $78,123,800 | 194,000 | Shares | Other | 2025-02-13 | |
| 2024-09-30 | $113,479,520 | 244,000 | Shares | Other | 2024-11-14 | |
| 2024-06-30 | $59,527,440 | 127,000 | Shares | Other | 2024-08-14 | |
| 2024-03-31 | $78,225,973 | 187,139 | Shares | Other | 2024-05-15 | |
| 2023-12-31 | $113,249,693 | 278,330 | Shares | Other | 2024-02-14 | |
| 2023-09-30 | $71,500,559 | 205,615 | Shares | Other | 2023-11-14 | |
| 2023-06-30 | $63,273,417 | 179,800 | Shares | Other | 2023-08-14 | |
| 2023-03-31 | $123,863,153 | 393,129 | Shares | Other | 2023-05-15 | |
| 2022-12-31 | $118,405,863 | 410,021 | Shares | Other | 2023-02-14 | |
| 2022-09-30 | $79,291,108 | 273,852 | Shares | Other | 2022-11-14 | |
| 2022-06-30 | $110,222,722 | 391,152 | Shares | Other | 2022-08-15 | |
| 2021-12-31 | $32,940,000 | 150,000 | Shares | Other | 2022-02-14 | |
| 2021-09-30 | $100,975,822 | 556,678 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $111,089,863 | 550,959 | Shares | Sole | 2021-08-13 | |
| 2021-03-31 | $40,125,979 | 186,728 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $47,170,391 | 199,587 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $11,284,272 | 41,468 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $1,341,812 | 4,622 | Shares | Sole | 2020-08-13 | |
| 2020-03-31 | $152,288 | 640 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||