BARCLAYS PLC

Position in VRTX — Vertex Pharmaceuticals Inc / Ma

CIK 312069 LONDON, X0

Back to VRTX Full portfolio

Position in VRTX

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$364,239,192

+$68,065,735 QoQ

Shares Held

733,274

+10.6% QoQ

Ownership

0.289%

of shares outstanding

% of Portfolio

0.15%

of 13F equity value

Holder Rank

#42

of 1,732 holders

Holding Since

Mar 2020

26 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in VRTX Over Time

Shares Held

Position Value (USD)

Derivatives in VRTX

reported options exposure · as of Mar 31, 2026

CallValue

CallShares

PutValue

$9,689,918

PutShares

21,700

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

BARCLAYS PLC holds $1,706,205,847 across 455 Biotechnology names. VRTX ranks #1 (21.3% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma This page	733,274	$364,239,192
2	REGN	Regeneron Pharmaceuticals, Inc.	256,192	$159,745,957
3	IONS	Ionis Pharmaceuticals Inc	1,603,136	$127,112,653
4	ARGX	Argenx SE	134,427	$124,717,337
5	MRNA	Moderna, Inc.	1,035,126	$72,489,872
6	BBIO	BridgeBio Pharma, Inc.	714,423	$53,210,224
7	TGTX	Tg Therapeutics, Inc.	957,848	$52,624,168
8	DNTH	Dianthus Therapeutics, Inc. /DE/	431,753	$42,087,281

All Filings in VRTX

Export CSV

50 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$364,239,192	733,274	+10.6%	Shares	Defined	2026-08-14
2026-03-31	$9,689,918	21,700	+442.5%	Put	Defined	2026-05-15
2026-03-31	$296,173,457	663,263	-21.8%	Shares	Defined	2026-05-15
2025-12-31	$1,813,440	4,000	0.0%	Put	Sole	2026-02-13
2025-12-31	$384,339,564	847,758	+14.2%	Shares	Sole	2026-02-13
2025-09-30	$1,566,560	4,000	0.0%	Put	Sole	2026-03-31
2025-09-30	$290,787,606	742,487	-9.8%	Shares	Defined	2026-03-31
2025-06-30	$1,780,800	4,000	0.0%	Put	Sole	2026-02-27
2025-06-30	$366,371,550	822,937	-0.4%	Shares	Sole	2026-02-27
2025-03-31	$400,427,379	825,930	-2.0%	Shares	Sole	2026-03-17
2025-03-31	$1,939,280	4,000	-85.7%	Put	Sole	2026-03-17
2024-12-31	$339,506,299	843,075	-10.2%	Shares	Defined	2026-03-19
2024-12-31	$11,235,330	27,900	+27.4%	Put	Sole	2026-03-19
2024-09-30	$10,185,252	21,900	-56.0%	Put	Sole	2026-03-31
2024-09-30	$436,866,384	939,336	+11.1%	Shares	Defined	2026-03-31
2024-09-30	$7,441,280	16,000	-57.4%	Call	Sole	2026-03-31
2024-06-30	$17,623,872	37,600	+1039.4%	Call	Sole	2026-03-23
2024-06-30	$396,378,690	845,662	+3.5%	Shares	Sole	2026-03-23
2024-03-31	$341,687,642	817,415	+1.3%	Shares	Sole	2026-03-24
2024-03-31	$20,816,898	49,800	+38.3%	Put	Sole	2026-03-24
2024-03-31	$1,379,433	3,300	+175.0%	Call	Sole	2026-03-24
2023-12-31	$488,268	1,200	+20.0%	Call	Sole	2026-03-24
2023-12-31	$328,262,168	806,759	+0.1%	Shares	Sole	2026-03-24
2023-12-31	$14,648,040	36,000	+59.3%	Put	Sole	2026-03-24
2023-09-30	$280,351,115	806,209	+26.8%	Shares	Sole	2026-03-26
2023-09-30	$7,858,924	22,600	-31.5%	Put	Sole	2026-03-26
2023-09-30	$347,740	1,000	-97.4%	Call	Sole	2026-03-26
2023-06-30	$223,809,479	635,985	+45.8%	Shares	Sole	2026-03-27
2023-03-31	$137,390,052	436,062	-28.7%	Shares	Sole	2026-03-30
2022-12-31	$9,529,740	33,000	0.0%	Put	Sole	2026-03-30
2022-12-31	$11,320,176	39,200	+84.9%	Call	Sole	2026-03-30
2022-12-31	$176,671,848	611,787	+48.2%	Shares	Sole	2026-03-30
2022-09-30	$9,554,820	33,000	-69.1%	Put	Sole	2022-11-03
2022-09-30	$119,551,063	412,900	+8.3%	Shares	Defined	2022-11-03
2022-09-30	$6,138,248	21,200	0.0%	Call	Sole	2022-11-03
2022-06-30	$30,095,172	106,800	-36.2%	Put	Sole	2022-08-12
2022-06-30	$5,973,948	21,200	0.0%	Call	Sole	2022-08-12
2022-06-30	$107,386,785	381,088	-33.4%	Shares	Defined	2022-08-12
2022-03-31	$5,532,564	21,200	-73.6%	Call	Sole	2022-05-16
2022-03-31	$149,283,973	572,035	-1.5%	Shares	Defined	2022-05-16
2021-12-31	$127,499,320	580,598	+2.1%	Shares	Defined	2022-02-14
2021-12-31	$36,761,040	167,400	+569.6%	Put	Sole	2022-02-14
2021-12-31	$17,655,840	80,400	-27.0%	Call	Sole	2022-02-14
2021-09-30	$103,157,034	568,703	+35.0%	Shares	Sole	2021-11-09
2021-06-30	$5,040,750	25,000	+4066.7%	Put	Sole	2021-08-13
2021-06-30	$84,927,765	421,206	+11.9%	Shares	Defined	2021-08-13
2021-06-30	$22,199,463	110,100	+78.7%	Call	Sole	2021-08-13
2021-03-31	$13,237,224	61,600	—	Call	Sole	2021-05-13
2021-03-31	$80,862,890	376,299	—	Shares	Sole	2021-05-13
2021-03-31	$128,934	600	—	Put	Sole	2021-05-13
No filing history on record for this holder in this stock.