BARCLAYS PLC

Position in VRTX — Vertex Pharmaceuticals Inc / Ma

CIK 312069 LONDON, X0

Back to VRTX Full portfolio

Position in VRTX

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$296,173,457

-$88,166,107 QoQ

Shares Held

663,263

-21.8% QoQ

Ownership

0.261%

of shares outstanding

% of Portfolio

0.13%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

25 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Common Shares in VRTX Over Time

Shares Held

Position Value (USD)

Derivatives in VRTX

reported options exposure · as of Mar 31, 2026

CallValue

CallShares

PutValue

$9,689,918

PutShares

21,700

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

BARCLAYS PLC holds $1,494,076,655 across 360 Biotechnology names. VRTX ranks #1 (19.8% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma This page	663,263	$296,173,457
2	REGN	Regeneron Pharmaceuticals, Inc.	313,093	$241,908,173
3	ALNY	Alnylam Pharmaceuticals, Inc.	220,623	$72,997,531
4	MRNA	Moderna, Inc.	932,269	$47,359,264
5	INSM	INSMED Inc	275,731	$45,087,531
6	ROIV	Roivant Sciences Ltd.	1,415,848	$39,218,988
7	RVMD	Revolution Medicines, Inc.	383,179	$37,264,156
8	TERN	Terns Pharmaceuticals, Inc.	669,601	$35,301,364

All Filings in VRTX

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50 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$9,689,918	21,700	-96.7%	Put	Defined	2026-05-15
2026-03-31	$296,173,457	663,263	+16481.6%	Shares	Defined	2026-05-15
2025-12-31	$1,813,440	4,000	-99.5%	Put	Sole	2026-02-13
2025-12-31	$384,339,564	847,758	+21094.0%	Shares	Sole	2026-02-13
2025-09-30	$1,566,560	4,000	-99.5%	Put	Sole	2026-03-31
2025-09-30	$290,787,606	742,487	-9.8%	Shares	Defined	2026-03-31
2025-06-30	$366,371,550	822,937	+20473.4%	Shares	Sole	2026-02-27
2025-06-30	$1,780,800	4,000	0.0%	Put	Sole	2026-02-27
2025-03-31	$1,939,280	4,000	-99.5%	Put	Sole	2026-03-17
2025-03-31	$400,427,379	825,930	-2.0%	Shares	Sole	2026-03-17
2024-12-31	$339,506,299	843,075	+2921.8%	Shares	Defined	2026-03-19
2024-12-31	$11,235,330	27,900	-97.0%	Put	Sole	2026-03-19
2024-09-30	$436,866,384	939,336	+4189.2%	Shares	Defined	2026-03-31
2024-09-30	$10,185,252	21,900	+36.9%	Put	Sole	2026-03-31
2024-09-30	$7,441,280	16,000	-98.1%	Call	Sole	2026-03-31
2024-06-30	$396,378,690	845,662	+2149.1%	Shares	Sole	2026-03-23
2024-06-30	$17,623,872	37,600	-95.4%	Call	Sole	2026-03-23
2024-03-31	$341,687,642	817,415	+24670.2%	Shares	Sole	2026-03-24
2024-03-31	$1,379,433	3,300	-93.4%	Call	Sole	2026-03-24
2024-03-31	$20,816,898	49,800	+38.3%	Put	Sole	2026-03-24
2023-12-31	$14,648,040	36,000	-95.5%	Put	Sole	2026-03-24
2023-12-31	$328,262,168	806,759	+67129.9%	Shares	Sole	2026-03-24
2023-12-31	$488,268	1,200	-94.7%	Call	Sole	2026-03-24
2023-09-30	$7,858,924	22,600	-97.2%	Put	Sole	2026-03-26
2023-09-30	$280,351,115	806,209	+80520.9%	Shares	Sole	2026-03-26
2023-09-30	$347,740	1,000	-99.8%	Call	Sole	2026-03-26
2023-06-30	$223,809,479	635,985	+45.8%	Shares	Sole	2026-03-27
2023-03-31	$137,390,052	436,062	-28.7%	Shares	Sole	2026-03-30
2022-12-31	$176,671,848	611,787	+1460.7%	Shares	Sole	2026-03-30
2022-12-31	$11,320,176	39,200	+18.8%	Call	Sole	2026-03-30
2022-12-31	$9,529,740	33,000	0.0%	Put	Sole	2026-03-30
2022-09-30	$9,554,820	33,000	-92.0%	Put	Sole	2022-11-03
2022-09-30	$119,551,063	412,900	+1847.6%	Shares	Defined	2022-11-03
2022-09-30	$6,138,248	21,200	-80.1%	Call	Sole	2022-11-03
2022-06-30	$30,095,172	106,800	+403.8%	Put	Sole	2022-08-12
2022-06-30	$5,973,948	21,200	-94.4%	Call	Sole	2022-08-12
2022-06-30	$107,386,785	381,088	+1697.6%	Shares	Defined	2022-08-12
2022-03-31	$5,532,564	21,200	-96.3%	Call	Sole	2022-05-16
2022-03-31	$149,283,973	572,035	-1.5%	Shares	Defined	2022-05-16
2021-12-31	$127,499,320	580,598	+246.8%	Shares	Defined	2022-02-23
2021-12-31	$36,761,040	167,400	+108.2%	Put	Sole	2022-02-23
2021-12-31	$17,655,840	80,400	-85.9%	Call	Sole	2022-02-23
2021-09-30	$103,157,034	568,703	+2174.8%	Shares	Sole	2021-11-09
2021-06-30	$5,040,750	25,000	-94.1%	Put	Sole	2021-08-13
2021-06-30	$84,927,765	421,206	+282.6%	Shares	Defined	2021-08-13
2021-06-30	$22,199,463	110,100	+78.7%	Call	Sole	2021-08-13
2021-03-31	$13,237,224	61,600	-83.6%	Call	Sole	2021-05-13
2021-03-31	$80,862,890	376,299	+62616.5%	Shares	Sole	2021-05-13
2021-03-31	$128,934	600	-98.9%	Put	Sole	2021-05-13
2020-12-31	$12,998,700	55,000	—	Put	Sole	2021-02-11
No filing history on record for this holder in this stock.