MANUFACTURERS LIFE INSURANCE COMPANY, THE

Insurance

Position in VRTX — Vertex Pharmaceuticals Inc / Ma

CIK 928047 TORONTO, A6

Back to VRTX Full portfolio

Position in VRTX

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$247,045,129

-$5,799,636 QoQ

Shares Held

553,243

-0.8% QoQ

Ownership

0.218%

of shares outstanding

% of Portfolio

0.24%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

25 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Common Shares in VRTX Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Mar 31, 2026

MANUFACTURERS LIFE INSURANCE COMPANY, THE holds $1,624,014,582 across 225 Biotechnology names. VRTX ranks #2 (15.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	REGN	Regeneron Pharmaceuticals, Inc.	408,931	$315,956,447
2	VRTX	Vertex Pharmaceuticals Inc / Ma This page	553,243	$247,045,129
3	ALNY	Alnylam Pharmaceuticals, Inc.	662,365	$219,156,707
4	BBIO	BridgeBio Pharma, Inc.	1,977,080	$146,817,960
5	JAZZ	Jazz Pharmaceuticals plc	535,062	$101,153,471
6	ARGX	Argenx SE	49,330	$36,023,232
7	PTCT	Ptc Therapeutics, Inc.	425,240	$28,971,601
8	AXSM	Axsome Therapeutics, Inc.	117,093	$19,791,058

All Filings in VRTX

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25 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$247,045,129	553,243	-0.8%	Shares	Defined	2026-05-15
2025-12-31	$252,844,765	557,713	+9.3%	Shares	Defined	2026-02-13
2025-09-30	$199,801,020	510,165	-6.7%	Shares	Defined	2025-11-14
2025-06-30	$243,504,811	546,956	+0.0%	Shares	Defined	2025-08-14
2025-03-31	$265,149,997	546,904	+0.3%	Shares	Defined	2025-05-15
2024-12-31	$219,618,888	545,366	-12.4%	Shares	Defined	2025-02-14
2024-09-30	$289,384,403	622,225	-1.8%	Shares	Defined	2024-11-13
2024-06-30	$296,969,274	633,575	-8.9%	Shares	Defined	2024-08-14
2024-03-31	$290,861,808	695,825	-15.0%	Shares	Defined	2024-05-14
2023-12-31	$333,162,752	818,803	-7.1%	Shares	Defined	2024-02-13
2023-09-30	$306,534,548	881,505	-5.1%	Shares	Defined	2023-11-15
2023-06-30	$326,719,226	928,417	+1.8%	Shares	Defined	2023-08-11
2023-03-31	$287,433,950	912,286	+8.8%	Shares	Defined	2023-05-15
2022-12-31	$242,246,857	838,863	+11.6%	Shares	Defined	2023-08-11
2022-09-30	$217,700,203	751,883	+0.3%	Shares	Defined	2023-08-11
2022-06-30	$211,284,733	749,795	+17.4%	Shares	Defined	2023-08-11
2022-03-31	$166,653,876	638,594	+33.9%	Shares	Defined	2023-08-11
2021-12-31	$104,731,631	476,920	-19.6%	Shares	Defined	2022-02-16
2021-09-30	$107,558,283	592,967	-1.0%	Shares	Defined	2021-11-12
2021-06-30	$120,723,945	598,740	-1.6%	Shares	Defined	2021-08-12
2021-03-31	$130,772,382	608,555	+42.0%	Shares	Defined	2021-05-03
2020-12-31	$101,320,847	428,708	+74.8%	Shares	Defined	2021-02-12
2020-09-30	$66,744,503	245,276	-11.4%	Shares	Defined	2020-11-09
2020-06-30	$80,336,323	276,726	-1.0%	Shares	Defined	2020-08-10
2020-03-31	$66,543,668	279,654	—	Shares	Defined	2020-05-15
No filing history on record for this holder in this stock.