Knott David M Jr

CIK

1892770

Location

SYOSSET, NY

Portfolio Value

Micro $2,207,395

Diversification

Diversified

Filing Date

Global Rank

#5,178 / 8,586 ▼ 584

Top Industry

Biotechnology 56.8%

3Y Alpha vs SPY

+3.6%

Period ended 3 months ago

Filed May 14, 2026 · 33d

18 quarters · since Dec 2021

Clone Performance

Jun 2023–Jun 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+94.3%

SPY

+78.1%

Annualised alpha

+3.6%

Max drawdown

−43.0%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

76 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

19.7%

−5.0 pts

Top 5

42.7%

−13.4 pts

Top 10

61.3%

−10.6 pts

HHI

650

Diversified−428

Portfolio Trend

18 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	70.6%	$90,016,627	47
Financial Services	25.7%	$32,717,921	5
Technology	1.7%	$2,207,395	7
Energy	0.7%	$861,759	2
Industrials	0.3%	$413,235	4
Consumer Defensive	0.3%	$404,448	2
Basic Materials	0.3%	$323,711	3
Real Estate	0.2%	$228,336	2
Consumer Cyclical	0.1%	$176,051	3
Communication Services	0.1%	$86,268	1

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

16 positions

Ticker	Company	Δ Shares	Shares	Value
CNTB	Connect Biopharma Holdings Ltd	+187,835	387,835	$1,016,127
XERS	Xeris Biopharma Holdings, Inc.	+90,000	1,060,000	$6,148,000
AGIO	Agios Pharmaceuticals, Inc.	+75,058	93,058	$3,148,152
HELP	Cybin Inc.	+64,818	350,000	$1,680,000
TGTX	Tg Therapeutics, Inc.	+45,001	90,001	$2,989,833
VRDN	Viridian Therapeutics, Inc.DE	+36,000	181,000	$3,540,360
CNTA	Centessa Pharmaceuticals plc	+35,000	39,000	$1,549,080
RZLT	Rezolute, Inc.	+30,000	370,000	$1,128,500
ALKS	Alkermes plc.	+25,000	120,000	$4,243,200
KURA	Kura Oncology, Inc.	+13,558	52,767	$428,995
RARE	Ultragenyx Pharmaceutical Inc.	+13,063	33,069	$692,795
SNDX	Syndax Pharmaceuticals Inc	+7,000	422,000	$9,857,920
BBIO	BridgeBio Pharma, Inc.	+5,000	90,000	$6,683,400
OBIO	Orchestra BioMed Holdings, Inc.	+3,651	253,651	$1,078,016
COGT	Cogent Biosciences, Inc.	+2,000	104,000	$4,002,960
PTHS	Pelthos Therapeutics Inc.	+1,792	21,073	$442,743
No positions match the current search.

Trimmed

Positions the filer reduced

13 positions

Ticker	Company	Δ Shares	Shares	Value
SLDB	Solid Biosciences Inc.	−115,297	47,143	$339,429
CPRX	Catalyst Pharmaceuticals, Inc.	−69,000	120,000	$2,971,200
WVE	Wave Life Sciences Ltd.	−50,000	40,000	$290,000
TVTX	Travere Therapeutics, Inc.	−45,367	140,633	$4,178,206
RCUS	Arcus Biosciences, Inc.	−40,000	81,241	$1,754,805
JSPR	Jasper Therapeutics, Inc.	−20,600	160,789	$140,851
LENZ	LENZ Therapeutics, Inc.	−20,000	33,732	$308,647
CYTK	Cytokinetics Inc	−10,356	23,644	$1,558,376
PTGX	Protagonist Therapeutics, Inc	−10,000	63,000	$6,640,200
BMY	Bristol Myers Squibb Co	−8,378	13,622	$826,174
ACLX	Arcellx, Inc.	−6,267	19,433	$2,231,297
BIIB	Biogen Inc.	−2,000	4,000	$733,320
JNJ	Johnson & Johnson	−2,000	4,922	$1,203,133
No positions match the current search.

New Positions

Positions the filer opened this quarter

7 positions

Ticker	Company	Shares	Value
IOVA	Iovance Biotherapeutics, Inc.	1,600,000	$5,616,000
RLMD	Relmada Therapeutics, Inc.	439,300	$3,057,528
ARDX	Ardelyx, Inc.	207,000	$1,239,930
VSTM	Verastem, Inc.	104,000	$551,200
CGEM	Cullinan Therapeutics, Inc.	24,200	$343,882
RAIN	Rain Enhancement Technologies Holdco, Inc.	101,686	$258,282
BRSL	Brightstar Lottery PLC	2,500	$31,850
No positions match the current search.

Sold Out

Positions the filer fully exited

10 positions

Ticker	Company	Shares	Value
CLMT	Calumet, Inc. /DE	2,214,969	$44,011,434
TECX	Tectonic Therapeutic, Inc.	74,000	$1,543,640
BHVN	Biohaven Ltd.	110,720	$1,250,028
NKTR	Nektar Therapeutics	15,500	$655,340
SRRK	Scholar Rock Holding Corp	13,913	$612,867
XENE	Xenon Pharmaceuticals Inc.	10,962	$491,316
FATE	Fate Therapeutics Inc	365,000	$357,700
DAWN	Day One Biopharmaceuticals, Inc.	25,884	$241,238
QURE	uniQure N.V.	4,000	$95,720
FSK	FS KKR Capital Corp	2,875	$42,578
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

7 positions · $2,207,395 total · Technology only · as of Mar 31, 2026

All sectors Basic Materials Communication Services Consumer Cyclical Consumer Defensive Energy Financial Services Healthcare Industrials Real Estate Technology

Ticker	Company	Type	Shares	Value (USD)	% Δ Value	% of Portfolio
KD	Kyndryl Holdings, Inc. Technology	Held	428	$5,615	−50.6%	0.25%
CRM	Salesforce, Inc. Technology	Held	77	$14,373	−29.5%	0.65%
AVGO	Broadcom Inc. Technology	Held	710	$219,752	−10.6%	9.96%
NVDA	Nvidia Corp Technology	Held	1,280	$223,232	−6.5%	10.11%
IBM	International Business Machines Corp Technology	Held	2,142	$519,199	−18.2%	23.52%
MSFT	Microsoft Corp Technology	Held	1,600	$592,272	−23.5%	26.83%
AAPL	Apple Inc. Technology	Held	2,494	$632,952	−6.6%	28.67%