Knott David M Jr
Filing Date
Global Rank
#5,189
/ 8,622
▼ 596
· as of Mar 2026
Top Industry
Biotechnology
56.8%
3Y Alpha vs SPY
+9.7%
Period ended 4 months ago
Filed May 14, 2026 · 3mo
18 quarters · since Dec 2021
Clone Performance
Jul 2023–Jul 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+112.1%
SPY
+67.9%
Annualised alpha
+9.6%
Max drawdown
−43.0%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 100% of reported value on average across 13 quarters. Past performance does not predict future results.
Portfolio Concentration
76 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
19.7%
−5.0 pts
Top 5
42.7%
−13.4 pts
Top 10
61.3%
−10.6 pts
HHI
650
Diversified−428
Portfolio Trend
18 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 70.6% | $90,016,627 |
| Financial Services | 25.7% | $32,717,921 |
| Technology | 1.7% | $2,207,395 |
| Energy | 0.7% | $861,759 |
| Industrials | 0.3% | $413,235 |
| Consumer Defensive | 0.3% | $404,448 |
| Basic Materials | 0.3% | $323,711 |
| Real Estate | 0.2% | $228,336 |
| Consumer Cyclical | 0.1% | $176,051 |
| Communication Services | 0.1% | $86,268 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
16 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| CNTB | Connect Biopharma Holdings Ltd | +187,835 | 387,835 | $1,016,127 | |
| XERS | Xeris Biopharma Holdings, Inc. | +90,000 | 1,060,000 | $6,148,000 | |
| AGIO | Agios Pharmaceuticals, Inc. | +75,058 | 93,058 | $3,148,152 | |
| HELP | Cybin Inc. | +64,818 | 350,000 | $1,680,000 | |
| TGTX | Tg Therapeutics, Inc. | +45,001 | 90,001 | $2,989,833 | |
| VRDN | Viridian Therapeutics, Inc.\DE | +36,000 | 181,000 | $3,540,360 | |
| CNTA | Centessa Pharmaceuticals plc | +35,000 | 39,000 | $1,549,080 | |
| RZLT | Rezolute, Inc. | +30,000 | 370,000 | $1,128,500 | |
| ALKS | Alkermes plc. | +25,000 | 120,000 | $4,243,200 | |
| KURA | Kura Oncology, Inc. | +13,558 | 52,767 | $428,995 | |
| RARE | Ultragenyx Pharmaceutical Inc. | +13,063 | 33,069 | $692,795 | |
| SNDX | Syndax Pharmaceuticals Inc | +7,000 | 422,000 | $9,857,920 | |
| BBIO | BridgeBio Pharma, Inc. | +5,000 | 90,000 | $6,683,400 | |
| OBIO | Orchestra BioMed Holdings, Inc. | +3,651 | 253,651 | $1,078,016 | |
| COGT | Cogent Biosciences, Inc. | +2,000 | 104,000 | $4,002,960 | |
| PTHS | Pelthos Therapeutics Inc. | +1,792 | 21,073 | $442,743 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
13 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| SLDB | Solid Biosciences Inc. | −115,297 | 47,143 | $339,429 | |
| CPRX | Catalyst Pharmaceuticals, Inc. | −69,000 | 120,000 | $2,971,200 | |
| WVE | Wave Life Sciences Ltd. | −50,000 | 40,000 | $290,000 | |
| TVTX | Travere Therapeutics, Inc. | −45,367 | 140,633 | $4,178,206 | |
| RCUS | Arcus Biosciences, Inc. | −40,000 | 81,241 | $1,754,805 | |
| JSPR | Jasper Therapeutics, Inc. | −20,600 | 160,789 | $140,851 | |
| LENZ | LENZ Therapeutics, Inc. | −20,000 | 33,732 | $308,647 | |
| CYTK | Cytokinetics Inc | −10,356 | 23,644 | $1,558,376 | |
| PTGX | Protagonist Therapeutics, Inc | −10,000 | 63,000 | $6,640,200 | |
| BMY | Bristol Myers Squibb Co | −8,378 | 13,622 | $826,174 | |
| ACLX | Arcellx, Inc. | −6,267 | 19,433 | $2,231,297 | |
| JNJ | Johnson & Johnson | −2,000 | 4,922 | $1,203,133 | |
| BIIB | Biogen Inc. | −2,000 | 4,000 | $733,320 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
7 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| IOVA | Iovance Biotherapeutics, Inc. | 1,600,000 | $5,616,000 | |
| RLMD | Relmada Therapeutics, Inc. | 439,300 | $3,057,528 | |
| ARDX | Ardelyx, Inc. | 207,000 | $1,239,930 | |
| VSTM | Verastem, Inc. | 104,000 | $551,200 | |
| CGEM | Cullinan Therapeutics, Inc. | 24,200 | $343,882 | |
| RAIN | Rain Enhancement Technologies Holdco, Inc. | 101,686 | $258,282 | |
| BRSL | Brightstar Lottery PLC | 2,500 | $31,850 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
10 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| CLMT | Calumet, Inc. /DE | 2,214,969 | $44,011,434 | |
| TECX | Tectonic Therapeutic, Inc. | 74,000 | $1,543,640 | |
| BHVN | Biohaven Ltd. | 110,720 | $1,250,028 | |
| NKTR | Nektar Therapeutics | 15,500 | $655,340 | |
| SRRK | Scholar Rock Holding Corp | 13,913 | $612,867 | |
| XENE | Xenon Pharmaceuticals Inc. | 10,962 | $491,316 | |
| FATE | Fate Therapeutics Inc | 365,000 | $357,700 | |
| DAWN | Day One Biopharmaceuticals, Inc. | 25,884 | $241,238 | |
| QURE | uniQure N.V. | 4,000 | $95,720 | |
| FSK | FS KKR Capital Corp | 2,875 | $42,578 | |
| No positions match the current search. | ||||
76 tracked positions ·
$127,435,751 total
· filing declares
88 positions · $168,034,091
· as of Mar 31, 2026
All sectors
Basic Materials
Communication Services
Consumer Cyclical
Consumer Defensive
Energy
Financial Services
Healthcare
Industrials
Real Estate
Technology
Showing 1–50
of 76 positions by value
· page 1 of 2
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| APO |
Apollo Global Management, Inc.
Financial Services
|
Held | 225,000 | $25,069,500 | 19.67% | |
| SNDX |
Syndax Pharmaceuticals Inc
Healthcare
|
Added | 422,000 | $9,857,920 | 7.74% | |
| BBIO |
BridgeBio Pharma, Inc.
Healthcare
|
Added | 90,000 | $6,683,400 | 5.24% | |
| PTGX |
Protagonist Therapeutics, Inc
Healthcare
|
Reduced | 63,000 | $6,640,200 | 5.21% | |
| XERS |
Xeris Biopharma Holdings, Inc.
Healthcare
|
Added | 1,060,000 | $6,148,000 | 4.82% | |
| JPM |
Jpmorgan Chase & Co
Financial Services
|
Held | 19,477 | $5,729,354 | 4.50% | |
| IOVA |
Iovance Biotherapeutics, Inc.
Healthcare
|
NEW | 1,600,000 | $5,616,000 | 4.41% | |
| ALKS |
Alkermes plc.
Healthcare
|
Added | 120,000 | $4,243,200 | 3.33% | |
| TVTX |
Travere Therapeutics, Inc.
Healthcare
|
Reduced | 140,633 | $4,178,206 | 3.28% | |
| COGT |
Cogent Biosciences, Inc.
Healthcare
|
Added | 104,000 | $4,002,960 | 3.14% | |
| VRDN |
Viridian Therapeutics, Inc.\DE
Healthcare
|
Added | 181,000 | $3,540,360 | 2.78% | |
| AGIO |
Agios Pharmaceuticals, Inc.
Healthcare
|
Added | 93,058 | $3,148,152 | 2.47% | |
| RLMD |
Relmada Therapeutics, Inc.
Healthcare
|
NEW | 439,300 | $3,057,528 | 2.40% | |
| TGTX |
Tg Therapeutics, Inc.
Healthcare
|
Added | 90,001 | $2,989,833 | 2.35% | |
| CPRX |
Catalyst Pharmaceuticals, Inc.
Healthcare
|
Reduced | 120,000 | $2,971,200 | 2.33% | |
| ACLX |
Arcellx, Inc.
Healthcare
|
Reduced | 19,433 | $2,231,297 | 1.75% | |
| AB |
Alliancebernstein Holding L.P.
Financial Services
|
Held | 48,000 | $1,797,120 | 1.41% | |
| RCUS |
Arcus Biosciences, Inc.
Healthcare
|
Reduced | 81,241 | $1,754,805 | 1.38% | |
| HELP |
Cybin Inc.
Healthcare
|
Added | 350,000 | $1,680,000 | 1.32% | |
| DCGO |
DocGo Inc.
Healthcare
|
Held | 2,670,850 | $1,679,964 | 1.32% | |
| CYTK |
Cytokinetics Inc
Healthcare
|
Reduced | 23,644 | $1,558,376 | 1.22% | |
| CNTA |
Centessa Pharmaceuticals plc
Healthcare
|
Added | 39,000 | $1,549,080 | 1.22% | |
| ATRC |
AtriCure, Inc.
Healthcare
|
Held | 51,400 | $1,466,442 | 1.15% | |
| ARDX |
Ardelyx, Inc.
Healthcare
|
NEW | 207,000 | $1,239,930 | 0.97% | |
| JNJ |
Johnson & Johnson
Healthcare
|
Reduced | 4,922 | $1,203,133 | 0.94% | |
| RZLT |
Rezolute, Inc.
Healthcare
|
Added | 370,000 | $1,128,500 | 0.89% | |
| OBIO |
Orchestra BioMed Holdings, Inc.
Healthcare
|
Added | 253,651 | $1,078,016 | 0.85% | |
| MDGL |
Madrigal Pharmaceuticals, Inc.
Healthcare
|
Held | 2,000 | $1,046,940 | 0.82% | |
| VERA |
Vera Therapeutics, Inc.
Healthcare
|
Held | 26,000 | $1,045,980 | 0.82% | |
| CNTB |
Connect Biopharma Holdings Ltd
Healthcare
|
Added | 387,835 | $1,016,127 | 0.80% | |
| PFE |
Pfizer Inc
Healthcare
|
Held | 32,337 | $908,022 | 0.71% | |
| BMY |
Bristol Myers Squibb Co
Healthcare
|
Reduced | 13,622 | $826,174 | 0.65% | |
| CNQ |
CANADIAN NATURAL RESOURCES Ltd
Energy
|
Held | 16,800 | $818,664 | 0.64% | |
| BIIB |
Biogen Inc.
Healthcare
|
Reduced | 4,000 | $733,320 | 0.58% | |
| RARE |
Ultragenyx Pharmaceutical Inc.
Healthcare
|
Added | 33,069 | $692,795 | 0.54% | |
| AAPL |
Apple Inc.
Technology
|
Held | 2,494 | $632,952 | 0.50% | |
| MSFT |
Microsoft Corp
Technology
|
Held | 1,600 | $592,272 | 0.46% | |
| VSTM |
Verastem, Inc.
Healthcare
|
NEW | 104,000 | $551,200 | 0.43% | |
| ADMA |
Adma Biologics, Inc.
Healthcare
|
Held | 60,200 | $542,402 | 0.43% | |
| IBM |
International Business Machines Corp
Technology
|
Held | 2,142 | $519,199 | 0.41% | |
| PTHS |
Pelthos Therapeutics Inc.
Healthcare
|
Added | 21,073 | $442,743 | 0.35% | |
| KURA |
Kura Oncology, Inc.
Healthcare
|
Added | 52,767 | $428,995 | 0.34% | |
| EOLS |
Evolus, Inc.
Healthcare
|
Held | 99,338 | $408,279 | 0.32% | |
| CGEM |
Cullinan Therapeutics, Inc.
Healthcare
|
NEW | 24,200 | $343,882 | 0.27% | |
| SLDB |
Solid Biosciences Inc.
Healthcare
|
Reduced | 47,143 | $339,429 | 0.27% | |
| LENZ |
LENZ Therapeutics, Inc.
Healthcare
|
Reduced | 33,732 | $308,647 | 0.24% | |
| WVE |
Wave Life Sciences Ltd.
Healthcare
|
Reduced | 40,000 | $290,000 | 0.23% | |
| RAIN |
Rain Enhancement Technologies Holdco, Inc.
Industrials
|
NEW | 101,686 | $258,282 | 0.20% | |
| KMB |
Kimberly Clark Corp
Consumer Defensive
|
Held | 2,400 | $231,528 | 0.18% | |
| NVDA |
Nvidia Corp
Technology
|
Held | 1,280 | $223,232 | 0.18% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.