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  • XERS Xeris Biopharma Holdings, Inc.

XERS

Xeris Biopharma Holdings, Inc.

Company with tickers: XERS

CIK
1867096
CUSIP
98422E103
Shares Outstanding
172,642,055
13F Activity (30d)
195 filings 190 filers
Holders: 235
Total Value: $616,878,895
Total Shares: 106,358,451
Showing 1–100 of 244 holdings by value · page 1 of 3

Institutional Ownership Trend

19 quarters

Holder Concentration

Across 235 13F filers · Δ vs Dec 31, 2025
Top Holder
12.2%
Jun 2023 → Mar 2026 · range 12.2% – 16.3%
−0.3 pts
Top 5
34.5%
Jun 2023 → Mar 2026 · range 33.8% – 57.9%
−4.8 pts
Top 10
49.0%
Jun 2023 → Mar 2026 · range 48.3% – 76.3%
−4.3 pts
HHI
375
Jun 2023 → Mar 2026 · range 375 – 819
Broadly held −73

Quarterly Activity

vs Dec 31, 2025
New
46
Increased
100
Decreased
54
Sold Out
38
Unchanged
35
Holder count: +8
Institutional value: -22.5%
Shares held: +4.9%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega MILLENNIUM MANAGEMENT LLC +1,406,923 2,265,974
Small Rosalind Advisors, Inc. +1,120,000 3,231,700
Mega UBS Group AG +1,044,544 1,646,378
Mid Voss Capital, LP +1,015,218 1,409,427
Large Caption Management, LLC +928,500 1,051,900

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Large Driehaus Capital Management LLC −2,077,827 902,740
Large Connor, Clark & Lunn Investment Management Ltd. −651,067 407,625
Large PRUDENTIAL FINANCIAL INC −561,810 57,139
Large VOLORIDGE INVESTMENT MANAGEMENT, LLC −441,013 370,116
Mega DEUTSCHE BANK AG\ −317,580 623,012

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 6,980,882 $40,489,115
Mega VANGUARD PORTFOLIO MANAGEMENT LLC 2,665,608 $15,460,526
Mid ARMISTICE CAPITAL, LLC 1,909,838 $11,077,060
Mega VANGUARD FIDUCIARY TRUST CO 1,133,902 $6,576,631
Small Stonepine Capital Management, LLC 320,030 $1,856,174

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 11,186,677 $87,815,411
Large ACADIAN ASSET MANAGEMENT LLC 971,598 $7,627,044
Large TWO SIGMA ADVISERS, LP 849,334 $6,667,271
Mega NORGES BANK 800,700 $6,285,495
Large Point72 Asset Management, L.P. 608,080 $4,773,428
Filter: New 46 Increased 100 Reduced 54 Sold out 38 Unchanged 35
Showing 100 of 244
All Common Calls Puts
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Holder Value (USD) % of 13F Shares Open
Mega BlackRock, Inc. $75,085,548 12.17% 12,945,785
Mega D. E. Shaw & Co., Inc. $45,175,103 7.32% 7,788,811
Mega VANGUARD CAPITAL MANAGEMENT LLC $40,489,115 6.56% 6,980,882
Mega STATE STREET CORP $27,017,409 4.38% 4,658,174
Mega GEODE CAPITAL MANAGEMENT, LLC $24,885,648 4.03% 4,290,629
Large Qube Research & Technologies Ltd $23,863,665 3.87% 4,114,425
Small Rosalind Advisors, Inc. $18,743,860 3.04% 3,231,700
Mega Nuveen, LLC $16,916,268 2.74% 2,916,598
Mega VANGUARD PORTFOLIO MANAGEMENT LLC $15,460,526 2.51% 2,665,608
Mega MORGAN STANLEY $14,921,389 2.42% 2,572,654
Mega MILLENNIUM MANAGEMENT LLC $13,142,649 2.13% 2,265,974
Mega WELLINGTON MANAGEMENT GROUP LLP $12,593,851 2.04% 2,171,354
Mega TWO SIGMA INVESTMENTS, LP $11,160,371 1.81% 1,924,202
Mid ARMISTICE CAPITAL, LLC $11,077,060 1.80% 1,909,838
Mega Legal & General Group Plc $11,068,074 1.79% 1,908,289
Small Parkman Healthcare Partners LLC $9,983,331 1.62% 1,721,264
Mega UBS Group AG $9,548,991 1.55% 1,646,378
Mega GOLDMAN SACHS GROUP INC $9,359,169 1.52% 1,613,650
Mega NORTHERN TRUST CORP Bank $8,378,777 1.36% 1,444,617
Mega AQR CAPITAL MANAGEMENT LLC $8,087,377 1.31% 1,394,376
Mid Voss Capital, LP $8,044,176 1.30% 1,386,927
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $7,886,010 1.28% 1,359,657
Mid CenterBook Partners LP $7,242,001 1.17% 1,248,621
Mid KENNEDY CAPITAL MANAGEMENT LLC $7,196,013 1.17% 1,240,692
Mid ALGERT GLOBAL LLC $6,710,356 1.09% 1,156,958
Mega VANGUARD FIDUCIARY TRUST CO Bank $6,576,631 1.07% 1,133,902
Small Knott David M Jr $6,148,000 1.00% 1,060,000
Small Ishara Investments LP $5,945,000 0.96% 1,025,000
Mid Granahan Investment Management, LLC $5,346,753 0.87% 921,854
Large Driehaus Capital Management LLC $5,235,892 0.85% 902,740
Mega BANK OF AMERICA CORP /DE/ Bank $5,071,502 0.82% 874,397
Large FEDERATED HERMES, INC. $4,969,515 0.81% 856,813
Large Trexquant Investment LP $4,832,658 0.78% 833,217
Small ESSEX INVESTMENT MANAGEMENT CO LLC $4,337,060 0.70% 747,769
Mega JANE STREET GROUP, LLC $4,208,572 0.68% 725,616
Mega CITADEL ADVISORS LLC $3,953,476 0.64% 681,634
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $3,874,827 0.63% 668,074
Large VOYA INVESTMENT MANAGEMENT LLC $3,626,797 0.59% 625,310
Mega DEUTSCHE BANK AG\ Bank $3,613,469 0.59% 623,012
Large Squarepoint Ops LLC $3,564,390 0.58% 614,550
Mega JPMORGAN CHASE & CO $3,552,377 0.58% 612,479
Large SEI INVESTMENTS CO $3,359,418 0.54% 579,210
Mega FMR LLC $2,975,840 0.48% 513,076
Large HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND Pension $2,691,687 0.44% 464,084
Large RENAISSANCE TECHNOLOGIES LLC $2,626,588 0.43% 452,860
Large Caption Management, LLC $2,572,300 0.42% 443,500
Mega Bank of New York Mellon Corp Bank $2,472,451 0.40% 426,285
Large Connor, Clark & Lunn Investment Management Ltd. $2,364,225 0.38% 407,625
Large Caption Management, LLC $2,339,720 0.38% 403,400
Large Russell Investments Group, Ltd. $2,228,328 0.36% 384,195
Mid IHT Wealth Management, LLC $2,183,560 0.35% 376,476
Mega CANADA PENSION PLAN INVESTMENT BOARD Pension $2,173,840 0.35% 374,800
Large VOLORIDGE INVESTMENT MANAGEMENT, LLC $2,146,672 0.35% 370,116
Mega Swiss National Bank Bank $1,904,140 0.31% 328,300
Large STATE OF WISCONSIN INVESTMENT BOARD $1,789,566 0.29% 308,546
Large Schonfeld Strategic Advisors LLC $1,719,299 0.28% 296,431
Mega JANUS HENDERSON GROUP PLC $1,713,835 0.28% 295,489
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,659,211 0.27% 286,071
Small Stonepine Capital Management, LLC $1,624,000 0.26% 280,000
Large Man Group plc $1,603,247 0.26% 276,422
Mega BNP PARIBAS ARBITRAGE, SA $1,524,164 0.25% 262,787
Mid ROYCE & ASSOCIATES LP $1,485,304 0.24% 256,087
Mid RICE HALL JAMES & ASSOCIATES, LLC $1,456,182 0.24% 251,066
Small Apella Capital, LLC $1,368,202 0.22% 235,897
Mid GROUP ONE TRADING LLC $1,265,241 0.21% 218,145
Mega PRICE T ROWE ASSOCIATES INC /MD/ $1,212,397 0.20% 209,034
Mega PRINCIPAL FINANCIAL GROUP INC $1,209,340 0.20% 208,507
Mega RAYMOND JAMES FINANCIAL INC $1,207,982 0.20% 208,273
Mid F/m Investments LLC $1,203,749 0.20% 207,543
Mid EMERALD MUTUAL FUND ADVISERS TRUST Mutual Fund $1,203,749 0.20% 207,543
Large Caption Management, LLC $1,189,000 0.19% 205,000
Large COMMONWEALTH EQUITY SERVICES, LLC $1,178,072 0.19% 203,116
Mega RHUMBLINE ADVISERS $1,108,188 0.18% 191,067
Mid Engineers Gate Manager LP $1,078,283 0.17% 185,911
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension $1,045,966 0.17% 180,339
Large HRT FINANCIAL LP $992,391 0.16% 171,102
Mid Y-Intercept (Hong Kong) Ltd $938,399 0.15% 161,793
Mega ALLIANCEBERNSTEIN L.P. $842,948 0.14% 145,336
Mega AMERIPRISE FINANCIAL INC $824,457 0.13% 142,148
Mega BARCLAYS PLC $803,607 0.13% 138,553
Mega ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $775,808 0.13% 133,760
Large Creative Planning $773,053 0.13% 133,285
Small DIADEMA PARTNERS LP $769,926 0.12% 132,746
Small Quarry LP $725,000 0.12% 125,000
Small GLOBEFLEX CAPITAL L P $714,467 0.12% 123,184
Large SG Americas Securities, LLC Broker-Dealer $707,083 0.11% 121,911
Large TUDOR INVESTMENT CORP ET AL $623,001 0.10% 107,414
Large PANAGORA ASSET MANAGEMENT INC $607,515 0.10% 104,744
Small Palo Alto Investors LP $605,578 0.10% 104,410
Mid WINTON GROUP Ltd $604,592 0.10% 104,240
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $603,200 0.10% 104,000
Mega VANGUARD ASSET MANAGEMENT, Ltd $600,619 0.10% 103,555
Mega Invesco Ltd. $599,103 0.10% 103,294
Mid GSA CAPITAL PARTNERS LLP $588,340 0.10% 101,438
Small TWINBEECH CAPITAL LP $563,760 0.09% 97,200
Small Round Rock Advisors LLC $561,532 0.09% 96,816
Small EntryPoint Capital, LLC $558,018 0.09% 96,210
Mega LPL Financial LLC $544,393 0.09% 93,861
Large Zurcher Kantonalbank (Zurich Cantonalbank) Bank $541,151 0.09% 93,302
Large Jefferies Financial Group Inc. $509,240 0.08% 87,800
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