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AGIO · Agios Pharmaceuticals, Inc.

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$35.97 -1.00 (-2.70%) At close · Jul 28
Market Cap
$2.14B
Shares
59.47M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

The Jun 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out.
Holders: 237
Total Value: $2,172,226,673
Total Shares: 63,971,382
Showing 1–100 of 250 holdings by value · page 1 of 3

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 235 13F filers
Top Holder
9.2%
Jun 2023 → Mar 2026 · range 8.6% – 9.8%
of institutional value
Top 5
36.3%
Jun 2023 → Mar 2026 · range 33.4% – 39.1%
of institutional value
Top 10
53.5%
Jun 2023 → Mar 2026 · range 51.1% – 60.3%
of institutional value
HHI
400
Jun 2023 → Mar 2026 · range 362 – 470
Broadly held
Showing 100 of 250
All Common Calls Puts
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Holder Value (USD) % of 13F Shares Open
Mega BlackRock, Inc. $194,690,188 8.96% 5,754,957
Large FARALLON CAPITAL MANAGEMENT LLC $192,289,720 8.85% 5,684,000
Mega STATE STREET CORP $113,833,856 5.24% 3,364,879
Mid ARMISTICE CAPITAL, LLC $108,256,000 4.98% 3,200,000
Mid ARMISTICE CAPITAL, LLC $91,882,280 4.23% 2,716,000
Mega D. E. Shaw & Co., Inc. $90,703,947 4.18% 2,681,169
Mega VANGUARD CAPITAL MANAGEMENT LLC $89,051,250 4.10% 2,632,316
Small Lynx1 Capital Management LP $88,349,345 4.07% 2,611,568
Large Erste Asset Management GmbH $79,968,339 3.68% 2,154,900
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. $53,479,816 2.46% 1,580,840
Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $50,556,736 2.33% 1,494,435
Mega T. Rowe Price Investment Management, Inc. $50,364,074 2.32% 1,488,740
Mega GEODE CAPITAL MANAGEMENT, LLC $49,659,395 2.29% 1,467,910
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $45,499,759 2.09% 1,344,953
Mid MPM BIOIMPACT LLC $44,190,809 2.03% 1,306,261
Mid Frazier Life Sciences Management, L.P. $42,493,186 1.96% 1,256,080
Large GW&K Investment Management, LLC $41,100,100 1.89% 1,214,901
Mega DIMENSIONAL FUND ADVISORS LP $38,959,099 1.79% 1,151,614
Mega MORGAN STANLEY $32,731,366 1.51% 967,525
Mega GOLDMAN SACHS GROUP INC $27,259,400 1.25% 805,776
Mid Rock Springs Capital Management LP $27,035,684 1.24% 799,163
Mega Nuveen, LLC $24,437,031 1.12% 722,348
Mega JANE STREET GROUP, LLC $23,181,668 1.07% 685,240
Mega WELLINGTON MANAGEMENT GROUP LLP $21,701,468 1.00% 641,486
Mega CITADEL ADVISORS LLC $20,961,506 0.96% 619,613
Mid SCS Capital Management LLC $20,732,715 0.95% 612,850
Small Foresite Capital Management VI LLC $17,760,750 0.82% 525,000
Mega NORTHERN TRUST CORP Bank $17,228,669 0.79% 509,272
Mega BANK OF AMERICA CORP /DE/ Bank $17,182,254 0.79% 507,900
Large Artisan Partners Limited Partnership $16,289,686 0.75% 481,516
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $16,137,992 0.74% 477,032
Large Connor, Clark & Lunn Investment Management Ltd. $15,226,646 0.70% 450,093
Mid Vestal Point Capital, LP $15,223,500 0.70% 450,000
Large MARSHALL WACE, LLP $15,159,830 0.70% 448,118
Mega Legal & General Group Plc $14,341,043 0.66% 423,915
Mid ArrowMark Colorado Holdings LLC $13,653,449 0.63% 403,590
Small Parkman Healthcare Partners LLC $13,651,250 0.63% 403,525
Mega VANGUARD FIDUCIARY TRUST CO Bank $12,923,770 0.59% 382,021
Mega BNP PARIBAS ARBITRAGE, SA $11,077,870 0.51% 327,457
Mega PRICE T ROWE ASSOCIATES INC /MD/ $10,107,828 0.47% 298,783
Mid KENNEDY CAPITAL MANAGEMENT LLC $9,318,676 0.43% 275,456
Mid ALGERT GLOBAL LLC $9,081,156 0.42% 268,435
Mega TWO SIGMA INVESTMENTS, LP $8,512,845 0.39% 251,636
Mega ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $8,473,095 0.39% 250,461
Large PANAGORA ASSET MANAGEMENT INC $8,067,372 0.37% 238,468
Small Palo Alto Investors LP $7,226,121 0.33% 213,601
Small Seven Fleet Capital Management LP $7,088,975 0.33% 209,547
Large Squarepoint Ops LLC $7,066,681 0.33% 208,888
Large Schonfeld Strategic Advisors LLC $6,768,063 0.31% 200,061
Mid Eversept Partners, LP $6,766,000 0.31% 200,000
Large HRT FINANCIAL LP $6,611,464 0.30% 195,432
Large Qube Research & Technologies Ltd $6,348,774 0.29% 187,667
Mega Bank of New York Mellon Corp Bank $6,319,136 0.29% 186,791
Mid GROUP ONE TRADING LLC $5,862,028 0.27% 173,279
Small Tetragon Partners GP Ltd $5,576,503 0.26% 164,839
Mid XTX Topco Ltd $5,442,570 0.25% 160,880
Mega JPMORGAN CHASE & CO $5,127,205 0.24% 151,558
Mega Invesco Ltd. $5,122,874 0.24% 151,430
Large Man Group plc $4,881,567 0.22% 144,297
Mid Edgestream Partners, L.P. $4,862,419 0.22% 143,731
Mid ADAR1 Capital Management, LLC $4,758,933 0.22% 140,672
Mega UBS Group AG $4,483,827 0.21% 132,540
Large CAPITAL FUND MANAGEMENT S.A. $4,382,033 0.20% 129,531
Large Pictet Asset Management Holding SA $4,357,777 0.20% 128,814
Small Exome Asset Management LLC $4,230,779 0.19% 125,060
Mega AMERICAN CENTURY COMPANIES INC $4,068,158 0.19% 120,253
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,954,727 0.18% 116,900
Large Assenagon Asset Management S.A. $3,857,770 0.18% 103,955
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $3,744,265 0.17% 110,679
Mega Swiss National Bank Bank $3,682,733 0.17% 108,860
Mega JANE STREET GROUP, LLC $3,623,193 0.17% 107,100
Small ESSEX INVESTMENT MANAGEMENT CO LLC $3,490,477 0.16% 103,177
Large Rafferty Asset Management, LLC $3,475,728 0.16% 102,741
Mid TANG CAPITAL MANAGEMENT LLC $3,383,000 0.16% 100,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,196,935 0.15% 94,500
Small Knott David M Jr $3,148,152 0.14% 93,058
Mid Caligan Partners LP $3,044,700 0.14% 90,000
Mega CITADEL ADVISORS LLC $2,845,103 0.13% 84,100
Large Trexquant Investment LP $2,547,331 0.12% 75,298
Large Woodline Partners LP $2,517,730 0.12% 74,423
Mega RHUMBLINE ADVISERS $2,482,073 0.11% 73,369
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension $2,319,520 0.11% 68,564
Mega CITADEL ADVISORS LLC $2,222,631 0.10% 65,700
Large SEI INVESTMENTS CO $2,149,895 0.10% 63,550
Mega CITIGROUP INC $2,127,907 0.10% 62,900
Mega CITIGROUP INC $2,127,907 0.10% 62,900
Mega ALLIANCEBERNSTEIN L.P. $2,080,342 0.10% 61,494
Large Universal- Beteiligungs- und Servicegesellschaft mbH $2,052,770 0.09% 60,679
Small Headlands Technologies LLC $2,004,664 0.09% 59,257
Mega VANGUARD ASSET MANAGEMENT, Ltd $1,984,061 0.09% 58,648
Large TUDOR INVESTMENT CORP ET AL $1,967,248 0.09% 58,151
Large SG Americas Securities, LLC Broker-Dealer $1,936,666 0.09% 57,247
Mega BARCLAYS PLC $1,773,976 0.08% 52,438
Large Hudson Bay Capital Management LP $1,753,408 0.08% 51,830
Large NEW YORK STATE COMMON RETIREMENT FUND Pension $1,749,247 0.08% 51,707
Mega DEUTSCHE BANK AG\ Bank $1,704,490 0.08% 50,384
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $1,693,056 0.08% 50,046
Mega JANE STREET GROUP, LLC $1,661,053 0.08% 49,100
Mega Capital International Investors $1,644,679 0.08% 48,616
Large ALPS ADVISORS INC $1,613,724 0.07% 47,701
Key facts CIK 1439222 CUSIP 00847X104 13F (30d) 61 filings 37 filers Visit website Investor relations

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