PRTA · Prothena Corp Public Ltd Co · Holdings

$8.25 -0.12 (-1.38%)

Russell 2000 member Rebalance outlook locked

Market Cap

$425.58M

51.34M

Volume · Oct 5 448.49K Avg daily vol (3M) 473.57K

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 190

Total Value: $472,951,824

Total Shares: 48,310,519

Showing 1–100 of 194 holdings by value · page 1 of 2

Institutional Ownership Trend

27 quarters

Holder Concentration

Across 190 13F filers

Top Holder

14.9%

of institutional value

Top 5

44.4%

of institutional value

Top 10

59.4%

of institutional value

HHI

566

Broadly held

Showing 100 of 194

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

FMR LLC

$70,480,343

14.90%

7,199,218

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	3,863,341	$37,822,108	53.7%	Defined
FIDELITY MANAGEMENT TRUST CO	3,335,877	$32,658,235	46.3%	Defined

Rubric Capital Management LP

$48,950,000

10.35%

5,000,000

BlackRock, Inc.

$47,657,275

10.08%

4,867,955

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	275,988	$2,701,922	5.7%	Sole
BlackRock Asset Management Canada Ltd	334	$3,269	0.0%	Sole
BlackRock Investment Management, LLC	122,036	$1,194,732	2.5%	Sole
BLACKROCK ADVISORS LLC	489,835	$4,795,484	10.1%	Sole
BlackRock Fund Advisors	2,002,911	$19,608,498	41.1%	Sole
BlackRock Institutional Trust Company, N.A.	1,681,614	$16,463,001	34.5%	Sole
BlackRock Japan Co. Ltd	12,292	$120,338	0.3%	Sole
BlackRock Investment Management (UK) Ltd.	40,161	$393,176	0.8%	Sole
BlackRock (Netherlands) B.V.	551	$5,394	0.0%	Sole
BlackRock Asset Management Ireland Ltd	125,019	$1,223,936	2.6%	Sole
Aperio Group, LLC	117,214	$1,147,525	2.4%	Sole

STATE STREET CORP

$23,431,620

4.95%

2,393,424

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	2,393,424	$23,431,620	100.0%	Defined

ACADIAN ASSET MANAGEMENT LLC

$19,684,214

4.16%

2,010,645

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Acadian Inc	2,010,645	$19,684,214	100.0%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$16,166,158

3.42%

1,651,293

D. E. Shaw & Co., Inc.

$15,776,164

3.34%

1,611,457

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	1,611,457	$15,776,164	100.0%	Defined

ADAR1 Capital Management, LLC

$15,218,897

3.22%

1,554,535

TWO SIGMA INVESTMENTS, LP

$12,384,222

2.62%

1,264,987

Palo Alto Investors LP

$11,191,487

2.37%

1,143,155

GEODE CAPITAL MANAGEMENT, LLC

$11,022,335

2.33%

1,125,877

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	161,031	$1,576,493	14.3%	Defined
Held directly	964,846	$9,445,842	85.7%	Defined

FEDERATED HERMES, INC.

$10,616,285

2.24%

1,084,401

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED EQUITY MANAGEMENT CO OF PENNSYLVANIA	141,447	$1,384,766	13.0%	Defined
FEDERATED MDTA LLC	942,954	$9,231,519	87.0%	Defined

MORGAN STANLEY

$9,744,453

2.06%

995,348

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	400	$3,916	0.0%	Defined
MORGAN STANLEY & CO. LLC	335,630	$3,285,817	33.7%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	443,931	$4,346,084	44.6%	Defined
MORGAN STANLEY SMITH BARNEY LLC	20,150	$197,267	2.0%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	195,237	$1,911,369	19.6%	Defined

GOLDMAN SACHS GROUP INC

$9,591,556

2.03%

979,730

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	797,983	$7,812,253	81.4%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	181,747	$1,779,303	18.6%	Defined

JACOBS LEVY EQUITY MANAGEMENT, INC

$9,457,022

2.00%

965,988

DIMENSIONAL FUND ADVISORS LP

$8,866,321

1.87%

905,651

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	4,985	$48,803	0.6%	Defined
DFA Australia Ltd.	17,962	$175,847	2.0%	Defined
Dimensional Ireland Ltd	38,008	$372,098	4.2%	Defined
Held directly	844,696	$8,269,573	93.3%	Sole

Qube Research & Technologies Ltd

$7,745,544

1.64%

791,169

RENAISSANCE TECHNOLOGIES LLC

$6,829,650

1.44%

697,615

Man Group plc

$6,638,755

1.40%

678,116

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Numeric Investors LLC	678,116	$6,638,755	100.0%	Defined

Mariner, LLC

$6,119,680

1.29%

625,095

Nuveen, LLC

$5,454,566

1.15%

557,157

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	15,593	$152,655	2.8%	Defined
TEACHERS ADVISORS, LLC joint	541,564	$5,301,911	97.2%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$4,698,661

0.99%

479,945

NORTHERN TRUST CORP

$4,475,243

0.95%

457,124

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	450,149	$4,406,958	98.5%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	6,975	$68,285	1.5%	Other

Birchview Capital, LP

$4,395,896

0.93%

449,019

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$4,120,611

0.87%

420,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	420,900	$4,120,611	100.0%	Other

Rangeley Capital, LLC

$4,085,073

0.86%

417,270

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$3,484,221

0.74%

355,896

CITADEL ADVISORS LLC

$3,316,949

0.70%

338,810

MONIMUS CAPITAL MANAGEMENT, LP

$3,221,419

0.68%

329,052

BNP PARIBAS ARBITRAGE, SA

$3,091,711

0.65%

315,803

AQR CAPITAL MANAGEMENT LLC

$2,962,178

0.63%

302,572

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prism Planning Partners LLC	42	$411	0.0%	Other
Arax Advisory Partners	4,203	$41,147	1.4%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	1,725	$16,887	0.6%	Other
Stokes Family Office, LLC	475	$4,650	0.2%	Other
Held directly	296,127	$2,899,083	97.9%	Defined

Penbrook Management LLC

$2,660,138

0.56%

271,720

VANGUARD FIDUCIARY TRUST CO

$2,536,236

0.54%

259,064

UBS Group AG

$2,363,550

0.50%

241,425

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	327	$3,201	0.1%	Defined
UBS AG	241,098	$2,360,349	99.9%	Defined

MACKENZIE FINANCIAL CORP

$2,348,611

0.50%

239,899

Squarepoint Ops LLC

$2,192,676

0.46%

223,971

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	223,971	$2,192,676	100.0%	Defined

BANK OF AMERICA CORP /DE/

$2,038,727

0.43%

208,246

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	177,165	$1,734,445	85.1%	Defined
BOFA SECURITIES, INC.	31,081	$304,282	14.9%	Defined

Focused Wealth Management, Inc

$2,030,886

0.43%

207,445

Connor, Clark & Lunn Investment Management Ltd.

$1,876,674

0.40%

191,693

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	191,146	$1,871,319	99.7%	Sole
Held directly	547	$5,355	0.3%	Sole

MARSHALL WACE, LLP

$1,868,263

0.40%

190,834

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	190,834	$1,868,263	100.0%	Other

Quantinno Capital Management LP

$1,550,060

0.33%

158,331

MILLENNIUM MANAGEMENT LLC

$1,467,521

0.31%

149,900

DIADEMA PARTNERS LP

$1,463,428

0.31%

149,482

CITADEL ADVISORS LLC

$1,393,117

0.29%

142,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	142,300	$1,393,117	100.0%	Defined

Bank of New York Mellon Corp

$1,310,937

0.28%

133,906

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	43,969	$430,456	32.8%	Defined
The Bank of New York Mellon	80,895	$791,962	60.4%	Defined
BNY Mellon, NA joint	2,210	$21,635	1.7%	Defined
Newton Investment Management North America, LLC	6,829	$66,855	5.1%	Defined
Held directly	3	$29	0.0%	Defined

MASSACHUSETTS FINANCIAL SERVICES CO /MA/

$1,243,231

0.26%

126,990

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MFS Heritage Trust CO	21,492	$210,406	16.9%	Defined
Held directly	105,498	$1,032,825	83.1%	Sole

Russell Investments Group, Ltd.

$1,193,407

0.25%

121,901

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC joint	63,318	$619,882	51.9%	Defined
Russell Investments Capital, LLC joint	11,706	$114,601	9.6%	Other
Russell Investments France SAS	7,251	$70,987	5.9%	Defined
Russell Investments Japan Co., LTD. joint	15,143	$148,249	12.4%	Other
Russell Investments Trust Company joint	24,483	$239,688	20.1%	Other

CITADEL ADVISORS LLC

$1,144,451

0.24%

116,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	116,900	$1,144,451	100.0%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$1,069,577

0.23%

109,252

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	109,252	$1,069,577	100.0%	Defined

JANE STREET GROUP, LLC

$1,014,244

0.21%

103,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	103,600	$1,014,244	100.0%	Defined

Hennion & Walsh Asset Management, Inc.

$888,883

0.19%

90,795

AMERICAN CENTURY COMPANIES INC

$887,404

0.19%

90,644

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	90,644	$887,404	100.0%	Defined

AMERIPRISE FINANCIAL INC

$853,834

0.18%

87,215

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	86,290	$844,779	98.9%	Defined
Ameriprise Financial Services, LLC	903	$8,840	1.0%	Defined
Ameriprise Bank, FSB	22	$215	0.0%	Defined

XTX Topco Ltd

$839,169

0.18%

85,717

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	85,717	$839,169	100.0%	Defined

Susquehanna Portfolio Strategies, LLC

$809,730

0.17%

82,710

ExodusPoint Capital Management, LP

$803,005

0.17%

82,023

MARTINGALE ASSET MANAGEMENT L P

$771,452

0.16%

78,800

Trexquant Investment LP

$751,196

0.16%

76,731

DCF Advisers, LLC

$717,088

0.15%

73,247

Invesco Ltd.

$699,778

0.15%

71,479

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	6,079	$59,513	8.5%	Defined
Invesco Trust Co joint	17,669	$172,979	24.7%	Defined
Invesco Capital Management LLC	47,731	$467,286	66.8%	Defined

STATE OF WISCONSIN INVESTMENT BOARD

$688,491

0.15%

70,326

Duncan Williams Asset Management, LLC

$688,050

0.15%

70,281

ALLIANCEBERNSTEIN L.P.

$677,634

0.14%

69,217

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	69,217	$677,634	100.0%	Defined

Campbell & CO Investment Adviser LLC

$669,097

0.14%

68,345

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$646,140

0.14%

66,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	66,000	$646,140	100.0%	Other

Assenagon Asset Management S.A.

$614,665

0.13%

62,785

Creative Planning

$613,049

0.13%

62,620

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	3,820	$37,397	6.1%	Defined
Held directly	58,800	$575,652	93.9%	Sole

PINNACLE ASSOCIATES LTD

$567,017

0.12%

57,918

CITIGROUP INC

$566,125

0.12%

57,827

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citibank, N.A. joint	237	$2,320	0.4%	Defined
Citigroup Financial Products Inc. joint	57,590	$563,805	99.6%	Defined

RHUMBLINE ADVISERS

$547,221

0.12%

55,896

Schonfeld Strategic Advisors LLC

$492,926

0.10%

50,350

EDGEWOOD MANAGEMENT LLC

$489,500

0.10%

50,000

Quinn Opportunity Partners LLC

$489,500

0.10%

50,000

HSBC HOLDINGS PLC

$485,280

0.10%

49,569

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HSBC BANK PLC	49,569	$485,280	100.0%	Defined

WELLS FARGO & COMPANY/MN

$484,800

0.10%

49,520

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	39,255	$384,306	79.3%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	266	$2,604	0.5%	Defined
WELLS FARGO CLEARING SERVICES, LLC	9,999	$97,890	20.2%	Defined

JANE STREET GROUP, LLC

$465,025

0.10%

47,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	47,500	$465,025	100.0%	Defined

Seven Fleet Capital Management LP

$423,907

0.09%

43,300

DEUTSCHE BANK AG\

$423,613

0.09%

43,270

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	513	$5,022	1.2%	Defined
DWS Investments UK Ltd	42,757	$418,591	98.8%	Defined

PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO

$412,726

0.09%

42,158

Engineers Gate Manager LP

$404,033

0.09%

41,270

Rafferty Asset Management, LLC

$395,486

0.08%

40,397

Virtus Investment Advisers, LLC

$388,271

0.08%

39,660

SHELTON CAPITAL MANAGEMENT

$386,430

0.08%

39,472

Persistent Asset Partners Ltd

$372,999

0.08%

38,100

BARCLAYS PLC

$368,329

0.08%

37,623

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	36,690	$359,195	97.5%	Defined
BARCLAYS CAPITAL INC.	933	$9,134	2.5%	Defined

SEI INVESTMENTS CO

$302,285

0.06%

30,877

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI INVESTMENTS MANAGEMENT CORP	104	$1,018	0.3%	Sole
SEI TRUST CO	30,773	$301,267	99.7%	Sole

WINTON GROUP Ltd

$298,595

0.06%

30,500

RBF Capital, LLC

$285,868

0.06%

29,200

GREAT LAKES ADVISORS, LLC

$281,296

0.06%

28,733

PNC FINANCIAL SERVICES GROUP, INC.

$277,897

0.06%

28,386

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	28,386	$277,897	100.0%	Defined

JPMORGAN CHASE & CO

$260,607

0.06%

26,620

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	18,440	$180,527	69.3%	Defined
J.P. Morgan Investment Management Inc.	4,450	$43,565	16.7%	Defined
J.P. Morgan Securities LLC	156	$1,527	0.6%	Defined
J.P. Morgan Securities plc	3,563	$34,881	13.4%	Defined
55I, LLC	11	$107	0.0%	Other

MetLife Investment Management, LLC

$253,463

0.05%

25,890

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	25,890	$253,463	100.0%	Defined

Aquatic Capital Management LLC

$248,852

0.05%

25,419

Covestor Ltd

$246,610

0.05%

25,190

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$246,452

0.05%

25,174

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	20,481	$200,508	81.4%	Defined
Global X Management (AUS) Ltd joint	4,693	$45,944	18.6%	Defined

Purkiss Capital Advisors LLC

$245,591

0.05%

25,086

TUDOR INVESTMENT CORP ET AL

$239,316

0.05%

24,445

CANADA PENSION PLAN INVESTMENT BOARD

$234,960

0.05%

24,000

ENVESTNET ASSET MANAGEMENT INC

$224,269

0.05%

22,908

MOGY JOEL R INVESTMENT COUNSEL INC

$203,142

0.04%

20,750

Key facts CIK 1559053 CUSIP G72800108 13F (30d) 5 filings 5 filers Visit website Investor relations