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Silence Therapeutics plc
$10.39 -0.11 (-1.05%) At close · Jul 2
Market Cap
$1.47B
Shares
141,703,840

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 56
Total Value: $105,188,616
Total Shares: 19,959,895

Institutional Ownership Trend

23 quarters

Holder Concentration

Across 56 13F filers · Δ vs Dec 31, 2025
Top Holder
15.2%
Jun 2023 → Mar 2026 · range 10.8% – 21.4%
−1.5 pts
Top 5
57.6%
Jun 2023 → Mar 2026 · range 41.1% – 71.3%
−1.7 pts
Top 10
80.4%
Jun 2023 → Mar 2026 · range 59.9% – 93.3%
+0.3 pts
HHI
843
Jun 2023 → Mar 2026 · range 500 – 1,234
Broadly held−60

Quarterly Activity

vs Dec 31, 2025
New
6
Increased
24
Decreased
11
Sold Out
8
Unchanged
15
Holder count: -2
Institutional value: -4.6%
Shares held: +10.1%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega CITADEL ADVISORS LLC +987,246 1,246,107
Mid Nantahala Capital Management, LLC +604,304 2,146,731
Mega MILLENNIUM MANAGEMENT LLC +414,599 1,074,191
Small Tetragon Partners GP Ltd +264,792 630,161
Small GREAT POINT PARTNERS LLC +212,457 1,020,489

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mega MORGAN STANLEY −259,144 65,486
Small Ishara Investments LP −99,500 140,500
Micro M28 Capital Management LP −83,897 101,203
Mega HSBC HOLDINGS PLC −50,000 122,834
Mega TWO SIGMA INVESTMENTS, LP −23,141 16,203

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Small Jones Hill Capital LP 301,604 $1,589,453
Large Squarepoint Ops LLC 89,469 $471,501
Large HRT FINANCIAL LP 11,994 $63,208
Small Dynamic Technology Lab Private Ltd 10,490 $55,282
Large ACADIAN ASSET MANAGEMENT LLC 4,818 $25,390

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mid Vivo Capital, LLC 1,105,454 $6,721,160
Small Lombard Odier Asset Management (USA) Corp 255,901 $1,555,878
Small Opaleye Management Inc. 78,926 $479,870
Mid Quadrature Capital Ltd 54,380 $330,630
Large TWO SIGMA ADVISERS, LP 15,900 $96,672
Filter: New 6 Increased 24 Reduced 11 Sold out 8 Unchanged 15
Showing 59 of 59
All Common Calls Puts
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Holder Value (USD) % of 13F Shares Open
Mid TCG Crossover Management, LLC $15,986,861 15.20% 3,033,560
Mid Siren, L.L.C. $15,343,278 14.59% 2,911,438
Mid Redmile Group, LLC $11,408,374 10.85% 2,164,777
Mid Nantahala Capital Management, LLC $11,313,272 10.76% 2,146,731
Mega CITADEL ADVISORS LLC $6,507,432 6.19% 1,234,807
Mega MILLENNIUM MANAGEMENT LLC $5,660,986 5.38% 1,074,191
Small GREAT POINT PARTNERS LLC $5,377,977 5.11% 1,020,489
Mid Nextech Invest, Ltd. $5,019,148 4.77% 952,400
Mid Ikarian Capital, LLC $4,562,681 4.34% 865,784
Small Tetragon Partners GP Ltd $3,320,948 3.16% 630,161
Small 5AM Venture Management, LLC $2,509,574 2.39% 476,200
Small Jones Hill Capital LP $1,589,453 1.51% 301,604
Large SG Americas Securities, LLC Broker-Dealer $1,510,898 1.44% 286,698
Mega UBS Group AG $1,301,357 1.24% 246,937
Mid BOOTHBAY FUND MANAGEMENT, LLC $1,101,893 1.05% 209,088
Mega BlackRock, Inc. $1,079,174 1.03% 204,777
Mega BANK OF MONTREAL /CAN/ Bank $1,069,288 1.02% 202,901
Mid ADAR1 Capital Management, LLC $907,267 0.86% 172,157
Large MARSHALL WACE, LLP $893,875 0.85% 169,616
Small Seven Fleet Capital Management LP $826,119 0.79% 156,759
Mega BNP PARIBAS ARBITRAGE, SA $778,210 0.74% 147,668
Small Ishara Investments LP $740,435 0.70% 140,500
Mega HSBC HOLDINGS PLC $647,335 0.62% 122,834
Large Point72 Asset Management, L.P. $630,876 0.60% 119,711
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $607,530 0.58% 115,281
Mid XTX Topco Ltd $558,630 0.53% 106,002
Large Qube Research & Technologies Ltd $551,004 0.52% 104,555
Micro M28 Capital Management LP $533,339 0.51% 101,203
Mega JANE STREET GROUP, LLC $531,884 0.51% 100,927
Large Squarepoint Ops LLC $471,501 0.45% 89,469
Mega MORGAN STANLEY $345,109 0.33% 65,486
Mega GOLDMAN SACHS GROUP INC $276,732 0.26% 52,511
Mega BANK OF AMERICA CORP /DE/ Bank $156,903 0.15% 29,773
Mega GEODE CAPITAL MANAGEMENT, LLC $155,665 0.15% 29,538
Mega RAYMOND JAMES FINANCIAL INC $131,750 0.13% 25,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $106,454 0.10% 20,200
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $99,603 0.09% 18,900
Mega TWO SIGMA INVESTMENTS, LP $85,389 0.08% 16,203
Mega RHUMBLINE ADVISERS $73,437 0.07% 13,935
Large HRT FINANCIAL LP $63,208 0.06% 11,994
Mega CITADEL ADVISORS LLC $59,551 0.06% 11,300
Small Dynamic Technology Lab Private Ltd $55,282 0.05% 10,490
Mid GAMMA Investing LLC $49,353 0.05% 9,365
Mid China Universal Asset Management Co., Ltd. $43,925 0.04% 8,335
Mega JPMORGAN CHASE & CO $40,241 0.04% 7,636
Large ACADIAN ASSET MANAGEMENT LLC $25,390 0.02% 4,818
Mega BARCLAYS PLC $15,477 0.01% 2,937
Large JONES FINANCIAL COMPANIES LLLP $13,175 0.01% 2,500
Large Mirae Asset Global Investments Co., Ltd. $12,911 0.01% 2,450
Mid Tower Research Capital LLC (TRC) $12,189 0.01% 2,313
Mega CITIGROUP INC $9,670 0.01% 1,835
Mid Parallel Advisors, LLC $6,851 0.01% 1,300
Mid GF FUND MANAGEMENT CO. LTD. $5,517 0.01% 1,047
Mid SIMPLEX TRADING, LLC $3,225 0.00% 612
Large Steward Partners Investment Advisory, LLC $527 0.00% 100
Large Rockefeller Capital Management L.P. $237 0.00% 45
Mid SBI Securities Co., Ltd. Broker-Dealer $147 0.00% 28
Mega ROYAL BANK OF CANADA Bank $84 0.00% 16
Small Caitong International Asset Management Co., Ltd $15 0.00% 3
Key facts CIK 1479615 CUSIP 82686Q101 Visit website Investor relations

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