IRLA · IRulya Therapeutics Inc. · Holdings
Substantial doubt about the company's ability to continue as a going concern.
“Factoring in these potential cash payments, based on its current operating plan, the Company believes that its cash and cash equivalents balance will not be sufficient to fund operations and capital expenditures for at least the twelve months following the issuance of these unaudited condensed consolidated financial statements. Accordingly, the Company concluded that substantial doubt about the Company's ability to continue as a going concern continues to exist within one year after the date these financial statements are available to be issued.”View the 10-Q filed Aug 14, 2026
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Institutional Ownership Trend
Holder Concentration
Across 28 13F filersWho Holds IRLA
Last 8 quarters through Sep 30, 2026 (filing window open)Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.
Jun 30, 2026, the newest closed quarter: 26 filers, like-for-like change +363.4%; actively managed books +389.2%; index-like books +163.1%.
| Holder type | Share | Filers | Change |
|---|---|---|---|
| Registered adviser | 86.4% | 14 | +519.3% |
| Bank | 1.4% | 5 | +199.8% |
| Holding company | 1.8% | 2 | +135.9% |
| Broker-dealer | 0.0% | 0 | -100.0% |
| Non-US | 0.0% | 0 | -100.0% |
| Exempt adviser | 0.0% | 0 | — |
| Benefit plan | 0.0% | 0 | — |
| Unknown | 10.4% | 5 | +62.7% |
| Style | Share | Filers | Change |
|---|---|---|---|
| Index-like | 6.5% | 4 | +163.1% |
| Systematic-like | 47.0% | 4 | +294.8% |
| Concentrated | 12.3% | 5 | +17778.0% |
| Diversified active | 34.2% | 13 | +379.2% |
| Not measured | 0.0% | 0 | — |
| Unknown | 0.0% | 0 | — |
| Turnover | Share | Filers | Change |
|---|---|---|---|
| Low turnover | 1.8% | 12 | -29.4% |
| Medium turnover | 3.2% | 4 | +12.4% |
| High turnover | 78.0% | 7 | +416.5% |
| Unknown | 17.0% | 3 | +1470.9% |
| Not measured | 0.0% | 0 | — |
| Holding horizon | Share | Filers | Change |
|---|---|---|---|
| Short horizon | 17.0% | 3 | +1314.6% |
| Medium horizon | 27.8% | 5 | +622.1% |
| Long horizon | 28.2% | 15 | +229.6% |
| Unknown | 27.1% | 3 | +239.1% |
| Not measured | 0.0% | 0 | — |
| 13F book size | Share | Filers | Change |
|---|---|---|---|
| Under $1B | 39.5% | 8 | +1264.9% |
| $1B to $10B | 6.1% | 4 | +1068.4% |
| $10B to $100B | 21.2% | 3 | +81.5% |
| $100B or more | 33.2% | 11 | +412.3% |
| Not measured | 0.0% | 0 | — |
| Client base | Share | Filers | Change |
|---|---|---|---|
| Individuals and high net worth | 0.1% | 7 | -90.2% |
| Pooled investment vehicles | 70.4% | 5 | +492.5% |
| Registered funds and BDCs | 3.6% | 1 | +422.1% |
| Other investment advisers | 0.0% | 0 | -100.0% |
| Diversified | 0.0% | 0 | -100.0% |
| Unknown | 25.8% | 13 | +238.5% |
| Private funds | Share | Filers | Change |
|---|---|---|---|
| Hedge funds | 81.0% | 5 | +583.1% |
| Private equity funds | 1.7% | 1 | +8627.0% |
| Real estate funds | 0.0% | 1 | 0.0% |
| Mixed private funds | 0.0% | 1 | new |
| No private funds | 3.7% | 6 | +86.3% |
| Other private funds | 0.0% | 0 | -100.0% |
| Unknown | 13.6% | 12 | +78.2% |
| Location | Share | Filers | Change |
|---|---|---|---|
| United States | 98.6% | 23 | +359.3% |
| Outside the US | 1.4% | 3 | +1049.3% |
The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.
How the mix is measured
Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.
Conviction and Crowding
26 13F filers, quarter ended Jun 30, 2026Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.
Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).
Shareholder Targets
13F filers that own its peers but not IRLA, quarter ended Jun 30, 2026Found through its holder-overlap peers: BIOA, ELVN, COGT. 378 filers in all.
| # | Filer | In peers | Largest peers |
|---|---|---|---|
| 1 | FMR LLC Holding company, Diversified active | $1,507,130,172 3 held | COGT, ELVN, BIOA |
| 2 | Polar Capital Holdings Plc Registered adviser, Diversified active | $477,751,351 3 held | ELVN, COGT, BIOA |
| 3 | ORBIMED ADVISORS LLC Registered adviser, Diversified active | $427,415,654 3 held | ELVN, COGT, BIOA |
| 4 | STATE STREET CORP Bank, Index-like | $356,169,459 3 held | COGT, ELVN, BIOA |
| 5 | VANGUARD PORTFOLIO MANAGEMENT LLC Registered adviser, Diversified active | $351,015,671 3 held | COGT, ELVN, BIOA |
| 6 | Jupiter Topco LLC Unknown, Diversified active | $339,605,762 3 held | COGT, BIOA, ELVN |
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ Registered adviser, Diversified active | $328,150,656 3 held | COGT, ELVN, BIOA |
| 8 | Fairmount Funds Management LLC Registered adviser, Concentrated | $307,156,209 2 held | COGT, ELVN |
| 9 | Commodore Capital LP Registered adviser, Concentrated | $284,241,250 2 held | ELVN, COGT |
| 10 | GEODE CAPITAL MANAGEMENT, LLC Registered adviser, Index-like | $270,528,232 3 held | COGT, ELVN, BIOA |
Fund Ownership of IRLA by Fund Type
Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026Index funds and index ETFs hold 1.18% of shares outstanding.
| Fund type | Of shares outstanding | Shares |
|---|---|---|
| Index funds | 0.00% | 0 |
| Index ETFs | 1.18% | 12,044 |
| Active ETFs | 0.00% | 0 |
| Active funds | 0.00% | 1 |
| Unclassified | 0.00% | 0 |
| All registered funds | 1.18% | 12,045 |
How fund types are measured
Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Large TUDOR INVESTMENT CORP ET AL Registered adviser | $2,142,782 | 19.04% | 117,800 | Put | 2026-08-14 | |
| Large TUDOR INVESTMENT CORP ET AL Registered adviser | $2,106,402 | 18.72% | 115,800 | Call | 2026-08-14 | |
| Small Ikarian Capital, LLC Registered adviser | $1,314,245 | 11.68% | 72,251 | Shares | 2026-08-14 | |
| Mega MILLENNIUM MANAGEMENT LLC Registered adviser | $1,287,470 | 11.44% | 70,779 | Shares | 2026-08-14 | |
| Large Balyasny Asset Management L.P. Registered adviser | $1,272,699 | 11.31% | 69,967 | Shares | 2026-08-14 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1,000,450 | 8.89% | 55,000 | Call | 2026-08-14 | |
| Small Squadron Capital Management LLC Registered adviser | $734,421 | 6.53% | 40,375 | Shares | 2026-08-14 | |
| Mid Shay Capital LLC | $317,742 | 2.82% | 17,468 | Shares | 2026-08-14 | |
| Mid BOOTHBAY FUND MANAGEMENT, LLC Registered adviser | $253,041 | 2.25% | 13,911 | Shares | 2026-08-14 | |
| Mega JANE STREET GROUP, LLC | $229,957 | 2.04% | 12,642 | Shares | 2026-08-14 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC Registered adviser | $219,080 | 1.95% | 12,044 | Shares | 2026-08-13 | |
| Mid Cormorant Asset Management, LP Registered adviser | $100,008 | 0.89% | 5,498 | Shares | 2026-08-14 | |
| Mega UBS Group AG Bank | $86,038 | 0.76% | 4,730 | Shares | 2026-08-13 | |
| Mega MORGAN STANLEY Holding company | $74,287 | 0.66% | 4,084 | Shares | 2026-08-13 | |
| Mega VANGUARD FIDUCIARY TRUST CO | $65,738 | 0.58% | 3,614 | Shares | 2026-08-13 | |
| Mega BlackRock, Inc. Holding company | $30,959 | 0.28% | 1,702 | Shares | 2026-08-07 | |
| Mid Tower Research Capital LLC (TRC) | $10,313 | 0.09% | 567 | Shares | 2026-08-11 | |
| Small Gen-Wealth Partners Inc Registered adviser | $3,001 | 0.03% | 165 | Shares | 2026-08-10 | |
| Small Operose Advisors LLC Registered adviser | $2,892 | 0.03% | 159 | Shares | 2026-08-13 | |
| Small Fortitude Family Office, LLC Registered adviser QNCX | $1,271 | 0.01% | 41 | Shares | 2026-10-14 | |
| Mega BARCLAYS PLC Bank | $491 | 0.00% | 27 | Shares | 2026-08-14 | |
| Mega WELLS FARGO & COMPANY/MN Bank | $181 | 0.00% | 10 | Shares | 2026-08-14 | |
| Large Allworth Financial LP | $145 | 0.00% | 8 | Shares | 2026-08-11 | |
| Mid Parallel Advisors, LLC Registered adviser | $54 | 0.00% | 3 | Shares | 2026-08-05 | |
| Small JDM Financial Group LLC Registered adviser | $18 | 0.00% | 1 | Shares | 2026-08-18 | |
| Large Steward Partners Investment Advisory, LLC Registered adviser | $18 | 0.00% | 1 | Shares | 2026-08-13 | |
| Mega ROYAL BANK OF CANADA Bank | $18 | 0.00% | 1 | Shares | 2026-08-14 | |
| Small Westside Investment Management, Inc. Registered adviser | $18 | 0.00% | 1 | Shares | 2026-07-27 | |
| Mega JPMORGAN CHASE & CO Bank | $2 | 0.00% | 2 | Shares | 2026-08-12 |