Tetragon Partners GP Ltd

CIK

1515070

Location

GRAND CAYMAN, E9

Portfolio Value

Small $515,114,916

Diversification

Highly concentrated

Filing Date

Global Rank

#2,552 / 8,603 ▲ 189 · as of Mar 2026

Top Industry

Software - Infrastructure 54.3%

3Y Alpha vs SPY

-10.6%

Period ended 3 months ago

Filed May 15, 2026 · 55d

25 quarters · since Mar 2020

Clone Performance

Jul 2023–Jul 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+35.7%

SPY

+76.0%

Annualised alpha

-10.0%

Max drawdown

−37.6%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

34 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

54.3%

−6.7 pts

Top 5

72.0%

−6.6 pts

Top 10

82.4%

−5.4 pts

HHI

3,082

Highly concentrated−748

Portfolio Trend

25 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Technology	62.7%	$322,720,369	5
Healthcare	25.1%	$129,507,633	27
Energy	7.3%	$37,521,426	1
Communication Services	4.9%	$25,365,488	1

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

16 positions

Ticker	Company	Δ Shares	Shares	Value
PATH	UiPath, Inc.	+7,757,628	25,207,628	$279,804,669
SLN	Silence Therapeutics plc	+264,792	630,161	$3,320,948
WK	Workiva Inc	+100,000	250,000	$14,907,500
CLDX	Celldex Therapeutics, Inc.	+68,516	312,316	$9,906,663
IMVT	Immunovant, Inc.	+52,320	218,507	$5,427,713
AMLX	Amylyx Pharmaceuticals, Inc.	+45,049	317,877	$4,418,490
HRMY	Harmony Biosciences Holdings, Inc.	+36,516	119,340	$3,342,713
NKTR	Nektar Therapeutics	+33,750	103,037	$7,413,512
ARWR	Arrowhead Pharmaceuticals, Inc.	+30,263	127,198	$7,975,314
AXSM	Axsome Therapeutics, Inc.	+28,125	55,059	$9,306,072
PHVS	Pharvaris N.V.	+26,999	221,611	$6,260,510
ALKS	Alkermes plc.	+18,619	159,791	$5,650,209
DYN	Dyne Therapeutics, Inc.	+10,135	258,132	$4,679,933
KRYS	Krystal Biotech, Inc.	+7,854	19,668	$5,080,637
AGIO	Agios Pharmaceuticals, Inc.	+2,821	164,839	$5,576,503
MBX	MBX Biosciences, Inc.	+2,153	145,480	$4,342,578
No positions match the current search.

Trimmed

Positions the filer reduced

4 positions

Ticker	Company	Δ Shares	Shares	Value
ANNX	Annexon, Inc.	−740,000	1,292,455	$7,160,200
KGEI	Kolibri Global Energy Inc.	−100,000	6,834,504	$37,521,426
MPLT	MapLight Therapeutics, Inc.	−52,410	112,115	$2,279,297
PRAX	Praxis Precision Medicines, Inc.	−7,000	15,952	$5,139,574
No positions match the current search.

New Positions

Positions the filer opened this quarter

10 positions

Ticker	Company	Shares	Value
WBD	Warner Bros. Discovery, Inc.	923,725	$25,365,488
DFTX	Definium Therapeutics, Inc.	199,994	$3,779,886
SLNO	Soleno Therapeutics Inc	102,125	$3,419,145
ACAD	Acadia Pharmaceuticals Inc	144,620	$3,219,241
IONS	Ionis Pharmaceuticals Inc	41,764	$3,136,058
RLAY	Relay Therapeutics, Inc.	181,543	$1,806,352
AARD	Aardvark Therapeutics, Inc.	316,621	$1,193,661
TECX	Tectonic Therapeutic, Inc.	37,588	$1,161,845
RARE	Ultragenyx Pharmaceutical Inc.	39,473	$826,959
KPTI	Karyopharm Therapeutics Inc.	102,984	$573,620
No positions match the current search.

Sold Out

Positions the filer fully exited

2 positions

Ticker	Company	Shares	Value
FOLD	AMICUS THERAPEUTICS, INC.	260,771	$3,713,379
ZVRA	Zevra Therapeutics, Inc.	192,518	$1,724,961
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

34 positions · $515,114,916 total · as of Mar 31, 2026

All sectors Communication Services Energy Healthcare Technology

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
PATH	UiPath, Inc. Technology	Added	25,207,628	+7,757,628	$279,804,669	−2.2%	54.32%
KGEI	Kolibri Global Energy Inc. Energy	Reduced	6,834,504	-100,000	$37,521,426	+37.7%	7.28%
WBD	Warner Bros. Discovery, Inc. Communication Services	NEW	923,725	NEW	$25,365,488	NEW	4.92%
WK	Workiva Inc Technology	Added	250,000	+100,000	$14,907,500	+15.2%	2.89%
LYFT	Lyft, Inc. Technology	Held	1,000,000	0	$13,300,000	−31.3%	2.58%
CXM	Sprinklr, Inc. Technology	Held	2,200,000	0	$13,200,000	−22.9%	2.56%
AUTL	Autolus Therapeutics plc Healthcare	Held	9,500,000	0	$13,110,000	−30.7%	2.55%
CLDX	Celldex Therapeutics, Inc. Healthcare	Added	312,316	+68,516	$9,906,663	+49.6%	1.92%
AXSM	Axsome Therapeutics, Inc. Healthcare	Added	55,059	+28,125	$9,306,072	+89.2%	1.81%
ARWR	Arrowhead Pharmaceuticals, Inc. Healthcare	Added	127,198	+30,263	$7,975,314	+23.9%	1.55%
NKTR	Nektar Therapeutics Healthcare	Added	103,037	+33,750	$7,413,512	+153.1%	1.44%
ANNX	Annexon, Inc. Healthcare	Reduced	1,292,455	-740,000	$7,160,200	−29.8%	1.39%
PHVS	Pharvaris N.V. Healthcare	Added	221,611	+26,999	$6,260,510	+15.9%	1.22%
ALKS	Alkermes plc. Healthcare	Added	159,791	+18,619	$5,650,209	+43.0%	1.10%
AGIO	Agios Pharmaceuticals, Inc. Healthcare	Added	164,839	+2,821	$5,576,503	+26.4%	1.08%
IMVT	Immunovant, Inc. Healthcare	Added	218,507	+52,320	$5,427,713	+28.5%	1.05%
PRAX	Praxis Precision Medicines, Inc. Healthcare	Reduced	15,952	-7,000	$5,139,574	−24.0%	1.00%
KRYS	Krystal Biotech, Inc. Healthcare	Added	19,668	+7,854	$5,080,637	+74.4%	0.99%
DYN	Dyne Therapeutics, Inc. Healthcare	Added	258,132	+10,135	$4,679,933	−3.5%	0.91%
AMLX	Amylyx Pharmaceuticals, Inc. Healthcare	Added	317,877	+45,049	$4,418,490	+34.1%	0.86%
MBX	MBX Biosciences, Inc. Healthcare	Added	145,480	+2,153	$4,342,578	−3.9%	0.84%
DFTX	Definium Therapeutics, Inc. Healthcare	NEW	199,994	NEW	$3,779,886	NEW	0.73%
SLNO	Soleno Therapeutics Inc Healthcare	NEW	102,125	NEW	$3,419,145	NEW	0.66%
HRMY	Harmony Biosciences Holdings, Inc. Healthcare	Added	119,340	+36,516	$3,342,713	+7.9%	0.65%
SLN	Silence Therapeutics plc Healthcare	Added	630,161	+264,792	$3,320,948	+49.5%	0.64%
ACAD	Acadia Pharmaceuticals Inc Healthcare	NEW	144,620	NEW	$3,219,241	NEW	0.62%
IONS	Ionis Pharmaceuticals Inc Healthcare	NEW	41,764	NEW	$3,136,058	NEW	0.61%
MPLT	MapLight Therapeutics, Inc. Healthcare	Reduced	112,115	-52,410	$2,279,297	−21.1%	0.44%
RLAY	Relay Therapeutics, Inc. Healthcare	NEW	181,543	NEW	$1,806,352	NEW	0.35%
SNOW	Snowflake Inc. Technology	Held	10,000	0	$1,508,200	−31.2%	0.29%
AARD	Aardvark Therapeutics, Inc. Healthcare	NEW	316,621	NEW	$1,193,661	NEW	0.23%
TECX	Tectonic Therapeutic, Inc. Healthcare	NEW	37,588	NEW	$1,161,845	NEW	0.23%
RARE	Ultragenyx Pharmaceutical Inc. Healthcare	NEW	39,473	NEW	$826,959	NEW	0.16%
KPTI	Karyopharm Therapeutics Inc. Healthcare	NEW	102,984	NEW	$573,620	NEW	0.11%