AMLX

Amylyx Pharmaceuticals, Inc.

Company with tickers: AMLX

CIK
1658551
CUSIP
03237H101
Shares Outstanding
111,186,317
Holders: 36
Total Value: $19,120,793
Total Shares: 1,375,598

Institutional Ownership Trend

17 quarters

Holder Concentration

Across 36 13F filers · Δ vs Dec 31, 2025
Top Holder
23.6%
+8.0 pts
Top 5
85.0%
+41.8 pts
Top 10
92.4%
+32.1 pts
HHI
1,772
Moderately concentrated +1,225

Quarterly Activity

vs Dec 31, 2025
New
35
Increased
0
Decreased
1
Sold Out
182
Unchanged
0
Holder count: -147
Institutional value: -98.5%
Shares held: -98.7%

Top Buyers

vs Dec 31, 2025
No qualifying movers this quarter.

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds
Small Essential Partners LLC −2 15

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD)
Mega UBS Group AG 324,319 $4,508,033
Mid iA Global Asset Management Inc. 304,786 $4,236,525
Mega Nuveen, LLC 264,897 $3,682,067
Mega Bank of New York Mellon Corp 251,104 $3,490,343
Large Police & Firemen's Retirement System of New Jersey 23,752 $330,152

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD)
Mega FMR LLC 16,518,419 $199,542,498
Mega BlackRock, Inc. 9,054,431 $109,377,522
Mid PERCEPTIVE ADVISORS LLC 8,284,882 $100,081,374
Mid TCG Crossover Management, LLC 6,243,812 $75,425,248
Mid COMMODORE CAPITAL LP 5,650,000 $68,252,000
Holder Value (USD) % of 13F Shares Action
Mega UBS Group AG $4,508,033 23.58% 324,319 View
Mid iA Global Asset Management Inc. $4,236,525 22.16% 304,786 View
Mega Nuveen, LLC $3,682,067 19.26% 264,897 View
Mega Bank of New York Mellon Corp $3,490,343 18.25% 251,104 View
Large Police & Firemen's Retirement System of New Jersey $330,152 1.73% 23,752 View
Large State of New Jersey Common Pension Fund D $313,014 1.64% 22,519 View
Mid PARSONS CAPITAL MANAGEMENT INC/RI $300,865 1.57% 21,645 View
Small Premier Path Wealth Partners, LLC $281,683 1.47% 20,265 View
Mid China Universal Asset Management Co., Ltd. $270,883 1.42% 19,488 View
Large ProShare Advisors LLC $252,340 1.32% 18,154 View
Large ARIZONA STATE RETIREMENT SYSTEM $251,576 1.32% 18,099 View
Large KLP KAPITALFORVALTNING AS $241,860 1.26% 17,400 View
Mid PROFUND ADVISORS LLC $238,412 1.25% 17,152 View
Mega HSBC HOLDINGS PLC $158,654 0.83% 11,414 View
Micro PSP Research LLC $150,648 0.79% 10,838 View
Large Pictet Asset Management Holding SA $149,675 0.78% 10,768 View
Large Mirae Asset Global Investments Co., Ltd. $79,619 0.42% 5,728 View
Large STRS OHIO $47,260 0.25% 3,400 View
Mid GF FUND MANAGEMENT CO. LTD. $34,124 0.18% 2,455 View
Mid LORING WOLCOTT & COOLIDGE FIDUCIARY ADVISORS LLP/MA $25,061 0.13% 1,803 View
Mid Sterling Capital Management LLC $15,804 0.08% 1,137 View
Large NISA INVESTMENT ADVISORS, LLC $12,815 0.07% 922 View
Micro Westfuller Advisors, LLC $11,384 0.06% 819 View
Large FIFTH THIRD BANCORP $10,494 0.05% 755 View
Mid GAMMA Investing LLC $5,796 0.03% 417 View
Small J.Safra Asset Management Corp $5,240 0.03% 377 View
Mid MassMutual Private Wealth & Trust, FSB $3,919 0.02% 282 View
Small Physician Wealth Advisors, Inc. $3,808 0.02% 274 View
Mid SIGNATUREFD, LLC $3,530 0.02% 254 View
Mid EASTERN BANK $2,780 0.01% 200 View
Micro Stone House Investment Management, LLC $1,014 0.01% 73 View
Mid SALEM INVESTMENT COUNSELORS INC $764 0.00% 55 View
Mid Farther Finance Advisors, LLC $305 0.00% 22 View
Small Essential Partners LLC $208 0.00% 15 View
Small Covestor Ltd $125 0.00% 9 View
Mid SBI Securities Co., Ltd. $13 0.00% 1 View