AMLX
Amylyx Pharmaceuticals, Inc.Company with tickers: AMLX
CIK
1658551
CUSIP
03237H101
Shares Outstanding
111,186,317
Price History
Institutional Holders
Short Volume
Short Interest
Fails to Deliver
Financials
SEC Filings
Earnings Calls
Insider Trades
Congressional Trades
Holders: 36
Total Value: $19,120,793
Total Shares: 1,375,598
Institutional Ownership Trend
Holder Concentration
Across 36 13F filers · Δ vs Dec 31, 2025Top Holder
23.6%
+8.0 pts
Top 5
85.0%
+41.8 pts
Top 10
92.4%
+32.1 pts
HHI
1,772
Moderately concentrated
+1,225
Quarterly Activity
vs Dec 31, 2025
New
35
Increased
0
Decreased
1
Sold Out
182
Unchanged
0
Holder count:
-147
Institutional value:
-98.5%
Shares held:
-98.7%
Top Buyers
vs Dec 31, 2025No qualifying movers this quarter.
Top Sellers
vs Dec 31, 2025| Institution | Sold | Now Holds |
|---|---|---|
| Small Essential Partners LLC | −2 | 15 |
Top New Positions
vs Dec 31, 2025| Institution | Acquired | Value (USD) |
|---|---|---|
| Mega UBS Group AG | 324,319 | $4,508,033 |
| Mid iA Global Asset Management Inc. | 304,786 | $4,236,525 |
| Mega Nuveen, LLC | 264,897 | $3,682,067 |
| Mega Bank of New York Mellon Corp | 251,104 | $3,490,343 |
| Large Police & Firemen's Retirement System of New Jersey | 23,752 | $330,152 |
Top Sold-Out Positions
vs Dec 31, 2025| Institution | Previously Held | Last Value (USD) |
|---|---|---|
| Mega FMR LLC | 16,518,419 | $199,542,498 |
| Mega BlackRock, Inc. | 9,054,431 | $109,377,522 |
| Mid PERCEPTIVE ADVISORS LLC | 8,284,882 | $100,081,374 |
| Mid TCG Crossover Management, LLC | 6,243,812 | $75,425,248 |
| Mid COMMODORE CAPITAL LP | 5,650,000 | $68,252,000 |
| Holder | Value (USD) | % of 13F | Shares | Type | Discretion | Filed | Action | |
|---|---|---|---|---|---|---|---|---|
| Mega UBS Group AG | $4,508,033 | 23.58% | 324,319 | Shares | Defined | 2026-05-05 | View | |
| Mid iA Global Asset Management Inc. | $4,236,525 | 22.16% | 304,786 | Shares | Sole | 2026-04-23 | View | |
| Mega Nuveen, LLC | $3,682,067 | 19.26% | 264,897 | Shares | Defined | 2026-04-30 | View | |
| Mega Bank of New York Mellon Corp | $3,490,343 | 18.25% | 251,104 | Shares | Defined | 2026-05-05 | View | |
| Large Police & Firemen's Retirement System of New Jersey | $330,152 | 1.73% | 23,752 | Shares | Defined | 2026-04-29 | View | |
| Large State of New Jersey Common Pension Fund D | $313,014 | 1.64% | 22,519 | Shares | Sole | 2026-05-05 | View | |
| Mid PARSONS CAPITAL MANAGEMENT INC/RI | $300,865 | 1.57% | 21,645 | Shares | Sole | 2026-04-15 | View | |
| Small Premier Path Wealth Partners, LLC | $281,683 | 1.47% | 20,265 | Shares | Sole | 2026-04-23 | View | |
| Mid China Universal Asset Management Co., Ltd. | $270,883 | 1.42% | 19,488 | Shares | Sole | 2026-04-28 | View | |
| Large ProShare Advisors LLC | $252,340 | 1.32% | 18,154 | Shares | Sole | 2026-04-27 | View | |
| Large ARIZONA STATE RETIREMENT SYSTEM | $251,576 | 1.32% | 18,099 | Shares | Sole | 2026-05-01 | View | |
| Large KLP KAPITALFORVALTNING AS | $241,860 | 1.26% | 17,400 | Shares | Sole | 2026-04-29 | View | |
| Mid PROFUND ADVISORS LLC | $238,412 | 1.25% | 17,152 | Shares | Sole | 2026-04-27 | View | |
| Mega HSBC HOLDINGS PLC | $158,654 | 0.83% | 11,414 | Shares | Defined | 2026-04-30 | View | |
| Micro PSP Research LLC | $150,648 | 0.79% | 10,838 | Shares | Sole | 2026-04-17 | View | |
| Large Pictet Asset Management Holding SA | $149,675 | 0.78% | 10,768 | Shares | Sole | 2026-04-22 | View | |
| Large Mirae Asset Global Investments Co., Ltd. | $79,619 | 0.42% | 5,728 | Shares | Sole | 2026-05-04 | View | |
| Large STRS OHIO | $47,260 | 0.25% | 3,400 | Shares | Sole | 2026-04-24 | View | |
| Mid GF FUND MANAGEMENT CO. LTD. | $34,124 | 0.18% | 2,455 | Shares | Sole | 2026-04-15 | View | |
| Mid LORING WOLCOTT & COOLIDGE FIDUCIARY ADVISORS LLP/MA | $25,061 | 0.13% | 1,803 | Shares | Sole | 2026-04-13 | View | |
| Mid Sterling Capital Management LLC | $15,804 | 0.08% | 1,137 | Shares | Sole | 2026-04-22 | View | |
| Large NISA INVESTMENT ADVISORS, LLC | $12,815 | 0.07% | 922 | Shares | Sole | 2026-04-30 | View | |
| Micro Westfuller Advisors, LLC | $11,384 | 0.06% | 819 | Shares | Sole | 2026-04-28 | View | |
| Large FIFTH THIRD BANCORP | $10,494 | 0.05% | 755 | Shares | Defined | 2026-05-01 | View | |
| Mid GAMMA Investing LLC | $5,796 | 0.03% | 417 | Shares | Defined | 2026-04-06 | View | |
| Small J.Safra Asset Management Corp | $5,240 | 0.03% | 377 | Shares | Sole | 2026-05-04 | View | |
| Mid MassMutual Private Wealth & Trust, FSB | $3,919 | 0.02% | 282 | Shares | Sole | 2026-04-13 | View | |
| Small Physician Wealth Advisors, Inc. | $3,808 | 0.02% | 274 | Shares | Sole | 2026-04-24 | View | |
| Mid SIGNATUREFD, LLC | $3,530 | 0.02% | 254 | Shares | Sole | 2026-04-07 | View | |
| Mid EASTERN BANK | $2,780 | 0.01% | 200 | Shares | Sole | 2026-04-07 | View | |
| Micro Stone House Investment Management, LLC | $1,014 | 0.01% | 73 | Shares | Sole | 2026-04-22 | View | |
| Mid SALEM INVESTMENT COUNSELORS INC | $764 | 0.00% | 55 | Shares | Sole | 2026-04-29 | View | |
| Mid Farther Finance Advisors, LLC | $305 | 0.00% | 22 | Shares | Sole | 2026-04-07 | View | |
| Small Essential Partners LLC | $208 | 0.00% | 15 | Shares | Sole | 2026-05-21 | View | |
| Small Covestor Ltd | $125 | 0.00% | 9 | Shares | Sole | 2026-05-05 | View | |
| Mid SBI Securities Co., Ltd. | $13 | 0.00% | 1 | Shares | Defined | 2026-04-28 | View | |
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