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  • SYRE Spyre Therapeutics, Inc.

SYRE

Spyre Therapeutics, Inc.

Company with tickers: SYRE

CIK
1636282
CUSIP
00773J202
Shares Outstanding
86,259,358
Price Holdings Short Volume Short Interest Fails to Deliver SEC Filings Earnings Calls Insider Trading Congress Trades
Report Date:
Holders: 154
Total Value: $2,528,641,953
Total Shares: 77,186,876
Showing top 100 of 154 holders by value
Holder Value (USD) Shares Action
FMR LLC $381,287,709 11,638,819 View
BlackRock, Inc. $180,904,021 5,522,101 View
RTW INVESTMENTS, LP $136,674,588 4,171,996 View
Fairmount Funds Management LLC $131,632,988 4,018,101 View
VR Adviser, LLC $120,735,276 3,685,448 View
Capital International Investors $114,415,643 3,492,541 View
PERCEPTIVE ADVISORS LLC $100,547,811 3,069,225 View
DRIEHAUS CAPITAL MANAGEMENT LLC $94,428,079 2,882,420 View
COMMODORE CAPITAL LP $78,238,906 2,388,245 View
STATE STREET CORP $74,130,605 2,262,839 View
TCG Crossover Management, LLC $62,263,066 1,900,582 View
TANG CAPITAL MANAGEMENT LLC $61,988,472 1,892,200 View
JANUS HENDERSON GROUP PLC $59,918,334 1,829,009 View
GEODE CAPITAL MANAGEMENT, LLC $54,353,425 1,659,140 View
BRAIDWELL LP $53,549,987 1,634,615 View
RA CAPITAL MANAGEMENT, L.P. $53,124,271 1,621,620 View
PRICE T ROWE ASSOCIATES INC /MD/ $52,477,654 1,601,882 View
WELLINGTON MANAGEMENT GROUP LLP $50,754,541 1,549,284 View
Paradigm Biocapital Advisors LP $48,067,634 1,467,266 View
Remedium Capital Partners, LLC $47,706,127 1,456,231 View
Affinity Asset Advisors, LLC $46,931,681 1,432,591 View
FRANKLIN RESOURCES INC $36,339,815 1,109,274 View
BAKER BROS. ADVISORS LP $32,760,000 1,000,000 View
Pictet Asset Management Holding SA $29,941,329 913,960 View
Siren, L.L.C. $26,817,270 818,598 View
Polar Capital Holdings Plc $24,253,079 740,326 View
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) $23,280,107 710,626 View
UBS Group AG $22,295,341 680,566 View
Point72 Asset Management, L.P. $21,698,618 662,351 View
EMERALD ADVISERS, LLC $20,838,930 636,109 View
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $18,824,616 574,622 View
NORTHERN TRUST CORP $18,379,110 561,023 View
Blackstone Group Inc $16,412,694 500,998 View
Candriam Luxembourg S.C.A. $13,940,493 425,534 View
BANK OF AMERICA CORP /DE/ $13,750,255 419,727 View
EMERALD MUTUAL FUND ADVISERS TRUST $13,509,273 412,371 View
Caption Management, LLC $13,100,724 399,900 View
GOLDMAN SACHS GROUP INC $9,011,129 275,065 View
Woodline Partners LP $8,710,621 265,892 View
Capital World Investors $6,557,634 200,172 View
ARMISTICE CAPITAL, LLC $6,434,915 196,426 View
Bank of New York Mellon Corp $6,317,109 192,830 View
HighVista Strategies LLC $6,165,628 188,206 View
SILVERARC CAPITAL MANAGEMENT, LLC $6,150,264 187,737 View
BARCLAYS PLC $5,979,485 182,524 View
Universal- Beteiligungs- und Servicegesellschaft mbH $5,608,872 171,211 View
Nuveen, LLC $4,946,103 150,980 View
Invesco Ltd. $4,944,597 150,934 View
Patient Square Capital LP $4,914,000 150,000 View
TD ASSET MANAGEMENT INC $4,908,168 149,822 View
VICTORY CAPITAL MANAGEMENT INC $4,785,548 146,079 View
MANUFACTURERS LIFE INSURANCE COMPANY, THE $4,226,465 129,013 View
Parkman Healthcare Partners LLC $4,078,128 124,485 View
DEUTSCHE BANK AG\ $3,994,786 121,941 View
MERCER GLOBAL ADVISORS INC /ADV $3,482,912 106,316 View
F/M Investments LLC $3,397,801 103,718 View
CITIGROUP INC $3,277,899 100,058 View
SEVEN GRAND MANAGERS, LLC $3,276,000 100,000 View
B Group, Inc. $3,276,000 100,000 View
Swiss National Bank $3,161,340 96,500 View
RHUMBLINE ADVISERS $2,717,638 82,956 View
WELLS FARGO & COMPANY/MN $2,699,947 82,416 View
DIMENSIONAL FUND ADVISORS LP $2,532,020 77,290 View
MILLENNIUM MANAGEMENT LLC $2,496,115 76,194 View
Balyasny Asset Management LLC $2,406,713 73,465 View
ALLIANCEBERNSTEIN L.P. $2,211,300 67,500 View
CITADEL ADVISORS LLC $2,093,495 63,904 View
ALPS ADVISORS INC $2,087,074 63,708 View
JPMORGAN CHASE & CO $2,062,273 62,951 View
UBS ASSET MANAGEMENT AMERICAS INC $2,038,195 62,216 View
SCHRODER INVESTMENT MANAGEMENT GROUP $2,017,164 61,574 View
Legal & General Group Plc $1,849,235 56,448 View
Rafferty Asset Management, LLC $1,749,711 53,410 View
Susquehanna Portfolio Strategies, LLC $1,739,588 53,101 View
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $1,573,724 48,038 View
AMERIPRISE FINANCIAL INC $1,253,266 38,256 View
MetLife Investment Management, LLC $1,245,240 38,011 View
ExodusPoint Capital Management, LP $1,240,653 37,871 View
Cinctive Capital Management LP $1,177,230 35,935 View
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1,151,316 35,144 View
StemPoint Capital LP $1,060,670 32,377 View
Voya Investment Management LLC $893,594 27,277 View
STATE OF WISCONSIN INVESTMENT BOARD $892,775 27,252 View
Warren Averett Asset Management, LLC $850,253 25,954 View
TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY $845,175 25,799 View
Optimize Financial Inc $829,843 25,331 View
VIRGINIA RETIREMENT SYSTEMS ET AL $817,362 24,950 View
CITADEL ADVISORS LLC $815,724 24,900 View
SG Americas Securities, LLC $764,716 23,343 View
Assenagon Asset Management S.A. $725,175 22,136 View
PROFUND ADVISORS LLC $674,626 20,593 View
NEW YORK STATE COMMON RETIREMENT FUND $627,845 19,165 View
Police & Firemen's Retirement System of New Jersey $601,473 18,360 View
INTECH INVESTMENT MANAGEMENT LLC $598,656 18,274 View
Neo Ivy Capital Management $598,230 18,261 View
Global Endowment Management, LP $595,707 18,184 View
AQR CAPITAL MANAGEMENT LLC $583,781 17,820 View
State of New Jersey Common Pension Fund D $547,026 16,698 View
ProShare Advisors LLC $523,799 15,989 View
PSP Research LLC $518,918 15,840 View

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