SYRE · Spyre Therapeutics, Inc.
Substantial doubt about the company's ability to continue as a going concern.
“We will need to raise additional capital to continue to fund our operations in the future. If we are unable to raise additional capital when needed, we will not be able to continue as a going concern.”View the 10-Q filed May 5, 2026
Total shares sold short and not yet covered, reported to FINRA by broker-dealers twice a month. Each reading settles on the 15th and the last business day of the month and is published seven business days later — the next scheduled dates are listed at the top of the table. Days to cover divides the short position by average daily volume; a high value (above 5) can signal short-squeeze potential.
Peer-relative percentile rank across all stocks reporting short interest at the latest settlement date (2026-07-15). Weighted mean of the available factors (short interest 30%, days to cover 20%, price vs VWAP 15%, short-volume trend 15%, short-interest change 10%, fails-to-deliver 10%) plus catalyst boosts (price spike, volume surge, earnings within days), capped at +20 and clamped to 100.
Short Interest History
| Settlement Date | Current Position | Previous Position | Change | Days to Cover |
|---|---|---|---|---|
|
2026-08-14
Scheduled
FINRA publishes Aug 25
|
— | — | — | — |
|
2026-07-31
Scheduled
FINRA publishes Aug 11
|
— | — | — | — |
| 2026-07-15 | 12,508,710 | 13,640,183 | -1,131,473 | 9.03 |
| 2026-06-30 | 13,640,183 | 12,616,535 | +1,023,648 | 5.56 |
| 2026-06-15 | 12,616,535 | 12,627,576 | -11,041 | 10.83 |
| 2026-05-29 | 12,627,576 | 12,417,051 | +210,525 | 15.47 |
| 2026-05-15 | 12,417,051 | 12,221,682 | +195,369 | 10.44 |
| 2026-04-30 | 12,221,682 | 11,672,747 | +548,935 | 10.04 |
| 2026-04-15 | 11,672,747 | 10,435,737 | +1,237,010 | 7.35 |
| 2026-03-31 | 10,435,737 | 9,997,086 | +438,651 | 11.48 |
| 2026-03-13 | 9,997,086 | 9,985,198 | +11,888 | 13.99 |
| 2026-02-27 | 9,985,198 | 9,862,924 | +122,274 | 12.42 |
| 2026-02-13 | 9,862,924 | 9,980,496 | -117,572 | 14.87 |
| 2026-01-30 | 9,980,496 | 10,069,741 | -89,245 | 20.29 |
| 2026-01-15 | 10,069,741 | 11,636,998 | -1,567,257 | 13.89 |
| 2025-12-31 | 11,636,998 | 11,818,159 | -181,161 | 14.06 |
| 2025-12-15 | 11,818,159 | 11,157,711 | +660,448 | 13.87 |
| 2025-11-28 | 11,157,711 | 12,464,842 | -1,307,131 | 18.26 |
| 2025-11-14 | 12,464,842 | 12,407,305 | +57,537 | 20.15 |
| 2025-10-31 | 12,407,305 | 13,390,470 | -983,165 | 11.89 |
| 2025-10-15 | 13,390,470 | 14,459,688 | -1,069,218 | 9.19 |
| 2025-09-30 | 14,459,688 | 13,780,763 | +678,925 | 18.19 |
| 2025-09-15 | 13,780,763 | 14,087,087 | -306,324 | 28.53 |
| 2025-08-29 | 14,087,087 | 13,187,699 | +899,388 | 29.35 |
| 2025-08-15 | 13,187,699 | 12,879,446 | +308,253 | 30.50 |
| 2025-07-31 | 12,879,446 | 13,602,876 | -723,430 | 23.35 |