SYRE · Spyre Therapeutics, Inc. · Options Chain

Track SYRE — free

$90.60 +1.89 (+2.13%) At close · Sep 11

Russell 2000 member Rebalance outlook locked

Market Cap

$7.99B

88.17M

Options Chain

Underlying $90.60 · at close Sep 11, 2026 Options Calculator

Pull option chains with greeks and open interest through the options chain API or MCP →

Positioning

Sep 18, 2026 · 5 days to expiry · 62 contracts · mixed daily-bar sessions · Feb 12, 2026–Sep 11, 2026; 13 unknown

Put / call OI

3.66

Put-heavy positioning

Open interest

2,450

as of Sep 10, 2026

Volume

—

dated and unknown daily-bar sessions

Max pain

$105.00

$14.40 above spot

ATM implied vol

70.9%

market's expected move

Open interest by strike · near the money

Calls Puts

17.5

22.5

100

105

110

115

120

125

130

135

140

145

150

155

160

Chain

Click any strike for greeks, breakeven and the calculator

Expiry

Sep 18 5d Oct 16 33d Nov 20 68d Dec 18 96d Jan 15 124d Mar 19 187d Dec 17 460d

Calls								Puts
OI	Vol	IV	Δ	Bid	Ask	Last	Strike	Last	Bid	Ask	Δ	IV	Vol	OI
3	1	—	—	$70.80	$75.50	$52.00		$1.35	$0.00	$0.20	—	—	1	1
Call · $17.5 In the money Daily-bar session Apr 13, 2026 Quote as of 2026-09-11 19:57:36.369 UTC Last $52.00 Breakeven $69.50 Implied vol — Delta — Gamma — Theta — Vega — Open interest 3 OI effective date Sep 10, 2026 Model this call Put · $17.5 Daily-bar session Feb 12, 2026 Quote as of 2026-09-11 19:56:35.933 UTC Last $1.35 Breakeven $16.15 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this put
1	1	—	—	$68.30	$73.00	$54.90		$2.20	$0.00	$0.50	—	—	1	1
Call · $20 In the money Daily-bar session Jun 3, 2026 Quote as of 2026-09-11 19:59:33.269 UTC Last $54.90 Breakeven $74.90 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this call Put · $20 Daily-bar session Feb 12, 2026 Quote as of 2026-09-11 13:31:17.766 UTC Last $2.20 Breakeven $17.80 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this put
1	1	—	—	$65.80	$70.50	$47.00		$1.90	$0.00	$4.90	—	—	1	1
Call · $22.5 In the money Daily-bar session Apr 13, 2026 Quote as of 2026-09-11 19:57:36.368 UTC Last $47.00 Breakeven $69.50 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this call Put · $22.5 Daily-bar session Feb 26, 2026 Quote as of 2026-09-11 19:59:50.773 UTC Last $1.90 Breakeven $20.60 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this put
—	—	—	—	$63.30	$68.00	—		—	$0.00	$4.90	—	—	—	—
Call · $25 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:32.418 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this call Put · $25 Daily-bar session Unknown Quote as of 2026-09-11 19:59:50.773 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
1	2	—	—	$58.30	$63.00	$19.44		$1.85	$0.00	$4.90	—	—	1	1
Call · $30 In the money Daily-bar session Mar 25, 2026 Quote as of 2026-09-11 19:57:36.368 UTC Last $19.44 Breakeven $49.44 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this call Put · $30 Daily-bar session Apr 10, 2026 Quote as of 2026-09-11 19:59:50.773 UTC Last $1.85 Breakeven $28.15 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this put
1	1	—	—	$53.30	$58.00	$16.03		—	$0.00	$4.90	—	—	—	—
Call · $35 In the money Daily-bar session Feb 24, 2026 Quote as of 2026-09-11 19:57:36.368 UTC Last $16.03 Breakeven $51.03 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this call Put · $35 Daily-bar session Unknown Quote as of 2026-09-11 17:48:22.438 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
15	1	—	—	$48.30	$53.00	$60.00		$8.60	$0.00	$4.90	—	—	1	3
Call · $40 In the money Daily-bar session Jun 22, 2026 Quote as of 2026-09-11 19:59:31.732 UTC Last $60.00 Breakeven $100.00 Implied vol — Delta — Gamma — Theta — Vega — Open interest 15 OI effective date Sep 10, 2026 Model this call Put · $40 Daily-bar session Mar 25, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $8.60 Breakeven $31.40 Implied vol — Delta — Gamma — Theta — Vega — Open interest 3 OI effective date Sep 10, 2026 Model this put
7	1	—	—	$43.30	$48.00	$24.41		$1.50	$0.00	$4.90	—	—	1	11
Call · $45 In the money Daily-bar session Apr 13, 2026 Quote as of 2026-09-11 19:59:31.817 UTC Last $24.41 Breakeven $69.41 Implied vol — Delta — Gamma — Theta — Vega — Open interest 7 OI effective date Sep 10, 2026 Model this call Put · $45 Daily-bar session May 18, 2026 Quote as of 2026-09-11 17:48:22.437 UTC Last $1.50 Breakeven $43.50 Implied vol — Delta — Gamma — Theta — Vega — Open interest 11 OI effective date Sep 10, 2026 Model this put
23	10	—	—	$38.30	$43.00	$11.70		—	$0.00	$4.90	—	—	—	—
Call · $50 In the money Daily-bar session Apr 7, 2026 Quote as of 2026-09-11 19:59:45.174 UTC Last $11.70 Breakeven $61.70 Implied vol — Delta — Gamma — Theta — Vega — Open interest 23 OI effective date Sep 10, 2026 Model this call Put · $50 Daily-bar session Unknown Quote as of 2026-09-11 17:48:22.438 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
3	1	—	—	$33.20	$37.80	$6.80		$1.80	$0.00	$4.90	—	—	10	12
Call · $55 In the money Daily-bar session Mar 9, 2026 Quote as of 2026-09-11 19:57:43.054 UTC Last $6.80 Breakeven $61.80 Implied vol — Delta — Gamma — Theta — Vega — Open interest 3 OI effective date Sep 10, 2026 Model this call Put · $55 Daily-bar session Aug 18, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $1.80 Breakeven $53.20 Implied vol — Delta — Gamma — Theta — Vega — Open interest 12 OI effective date Sep 10, 2026 Model this put
3	6	—	—	$28.20	$32.80	$23.10		$2.48	$0.00	$4.90	—	—	1	1
Call · $60 In the money Daily-bar session May 11, 2026 Quote as of 2026-09-11 19:57:41.256 UTC Last $23.10 Breakeven $83.10 Implied vol — Delta — Gamma — Theta — Vega — Open interest 3 OI effective date Sep 10, 2026 Model this call Put · $60 Daily-bar session Aug 28, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $2.48 Breakeven $57.52 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this put
40	2	—	—	$23.20	$27.80	$25.79		$2.53	$0.00	$4.90	—	—	1	5
Call · $65 In the money Daily-bar session Jul 6, 2026 Quote as of 2026-09-11 19:57:48.349 UTC Last $25.79 Breakeven $90.79 Implied vol — Delta — Gamma — Theta — Vega — Open interest 40 OI effective date Sep 10, 2026 Model this call Put · $65 Daily-bar session Aug 28, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $2.53 Breakeven $62.47 Implied vol — Delta — Gamma — Theta — Vega — Open interest 5 OI effective date Sep 10, 2026 Model this put
6	1	—	—	$19.00	$22.10	$17.93		$1.82	$0.00	$4.90	—	—	1	51
Call · $70 In the money Daily-bar session Sep 4, 2026 Quote as of 2026-09-11 19:59:31.067 UTC Last $17.93 Breakeven $87.93 Implied vol — Delta — Gamma — Theta — Vega — Open interest 6 OI effective date Sep 10, 2026 Model this call Put · $70 Daily-bar session Sep 4, 2026 Quote as of 2026-09-11 19:57:40.158 UTC Last $1.82 Breakeven $68.18 Implied vol — Delta — Gamma — Theta — Vega — Open interest 51 OI effective date Sep 10, 2026 Model this put
16	1	80%	0.981	$13.50	$17.90	$14.18		$0.20	$0.10	$1.05	—	—	2	241
Call · $75 In the money Daily-bar session Sep 4, 2026 Quote as of 2026-09-11 19:57:36.351 UTC Last $14.18 Breakeven $89.18 Implied vol 80% Delta 0.981 ≈98% ITM Gamma 0.006 Theta -0.047 Vega 0.005 Open interest 16 OI effective date Sep 10, 2026 Model this call Put · $75 Daily-bar session Sep 11, 2026 Quote as of 2026-09-11 19:58:30.385 UTC Last $0.20 Breakeven $74.80 Implied vol — Delta — Gamma — Theta — Vega — Open interest 241 OI effective date Sep 10, 2026 Model this put
18	3	62.2%	0.96	$8.50	$13.00	$9.93		$0.40	$0.00	$1.40	—	—	1	65
Call · $80 In the money Daily-bar session Sep 11, 2026 Quote as of 2026-09-11 19:59:30.904 UTC Last $9.93 Breakeven $89.93 Implied vol 62.2% Delta 0.96 ≈96% ITM Gamma 0.013 Theta -0.064 Vega 0.009 Open interest 18 OI effective date Sep 10, 2026 Model this call Put · $80 Daily-bar session Sep 11, 2026 Quote as of 2026-09-11 19:57:40.185 UTC Last $0.40 Breakeven $79.60 Implied vol — Delta — Gamma — Theta — Vega — Open interest 65 OI effective date Sep 10, 2026 Model this put
50	25	72.3%	0.789	$4.70	$8.50	$4.35		$1.53	$0.00	$4.00	—	—	17	214
Call · $85 In the money Daily-bar session Sep 10, 2026 Quote as of 2026-09-11 19:59:30.854 UTC Last $4.35 Breakeven $89.35 Implied vol 72.3% Delta 0.789 ≈79% ITM Gamma 0.038 Theta -0.228 Vega 0.031 Open interest 50 OI effective date Sep 10, 2026 Model this call Put · $85 Daily-bar session Sep 11, 2026 Quote as of 2026-09-11 19:55:29.744 UTC Last $1.53 Breakeven $83.47 Implied vol — Delta — Gamma — Theta — Vega — Open interest 214 OI effective date Sep 10, 2026 Model this put
57	3	66.8%	0.552	$1.60	$4.70	$3.50		$4.60	$0.80	$4.90	-0.45	75.1%	1	88
Call · $90 In the money Daily-bar session Sep 11, 2026 Quote as of 2026-09-11 19:59:51.991 UTC Last $3.50 Breakeven $93.50 Implied vol 66.8% Delta 0.552 ≈55% ITM Gamma 0.056 Theta -0.285 Vega 0.042 Open interest 57 OI effective date Sep 10, 2026 Model this call Put · $90 Daily-bar session Sep 9, 2026 Quote as of 2026-09-11 19:59:32.919 UTC Last $4.60 Breakeven $85.40 Implied vol 75.1% Delta -0.45 ≈45% ITM Gamma 0.05 Theta -0.311 Vega 0.042 Open interest 88 OI effective date Sep 10, 2026 Model this put
Underlying $90.60
162	4	—	—	$0.00	$2.50	$2.80		$6.00	$4.00	$8.00	-0.679	78.3%	15	35
Call · $95 Daily-bar session Sep 1, 2026 Quote as of 2026-09-11 19:58:23.379 UTC Last $2.80 Breakeven $97.80 Implied vol — Delta — Gamma — Theta — Vega — Open interest 162 OI effective date Sep 10, 2026 Model this call Put · $95 In the money Daily-bar session Sep 8, 2026 Quote as of 2026-09-11 19:59:30.858 UTC Last $6.00 Breakeven $89.00 Implied vol 78.3% Delta -0.679 ≈68% ITM Gamma 0.043 Theta -0.29 Vega 0.038 Open interest 35 OI effective date Sep 10, 2026 Model this put
20	1	—	—	$0.00	$4.90	$0.05		$11.00	$8.60	$11.50	-0.839	81%	70	30
Call · $100 Daily-bar session Sep 11, 2026 Quote as of 2026-09-11 19:55:24.353 UTC Last $0.05 Breakeven $100.05 Implied vol — Delta — Gamma — Theta — Vega — Open interest 20 OI effective date Sep 10, 2026 Model this call Put · $100 In the money Daily-bar session Aug 27, 2026 Quote as of 2026-09-11 19:59:30.867 UTC Last $11.00 Breakeven $89.00 Implied vol 81% Delta -0.839 ≈84% ITM Gamma 0.029 Theta -0.201 Vega 0.026 Open interest 30 OI effective date Sep 10, 2026 Model this put
30	1	—	—	$0.00	$4.90	$0.50		$18.20	$13.80	$15.10	-0.963	68.7%	150	1.2k
Call · $105 Daily-bar session Sep 9, 2026 Quote as of 2026-09-11 19:59:30.868 UTC Last $0.50 Breakeven $105.50 Implied vol — Delta — Gamma — Theta — Vega — Open interest 30 OI effective date Sep 10, 2026 Model this call Put · $105 In the money Daily-bar session Sep 4, 2026 Quote as of 2026-09-11 19:59:56.748 UTC Last $18.20 Breakeven $86.80 Implied vol 68.7% Delta -0.963 ≈96% ITM Gamma 0.011 Theta -0.048 Vega 0.009 Open interest 1.2k OI effective date Sep 10, 2026 Model this put
10	1	—	—	$0.00	$4.90	$0.55		$24.26	$17.20	$21.90	-0.95	97.2%	6	1
Call · $110 Daily-bar session Sep 3, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $0.55 Breakeven $110.55 Implied vol — Delta — Gamma — Theta — Vega — Open interest 10 OI effective date Sep 10, 2026 Model this call Put · $110 In the money Daily-bar session Sep 2, 2026 Quote as of 2026-09-11 19:59:55.668 UTC Last $24.26 Breakeven $85.74 Implied vol 97.2% Delta -0.95 ≈95% ITM Gamma 0.01 Theta -0.096 Vega 0.011 Open interest 1 OI effective date Sep 10, 2026 Model this put
2	1	—	—	$0.00	$4.90	$0.55		—	$22.00	$26.70	-0.996	75.3%	—	—
Call · $115 Daily-bar session Sep 2, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $0.55 Breakeven $115.55 Implied vol — Delta — Gamma — Theta — Vega — Open interest 2 OI effective date Sep 10, 2026 Model this call Put · $115 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:31.172 UTC Last — Breakeven — Implied vol 75.3% Delta -0.996 ≈100% ITM Gamma 0.002 Theta 0.003 Vega 0.001 Open interest — OI effective date — Model this put
3	3	—	—	$0.00	$4.90	$0.29		—	$27.00	$31.70	—	—	—	—
Call · $120 Daily-bar session Sep 1, 2026 Quote as of 2026-09-11 18:26:52.138 UTC Last $0.29 Breakeven $120.29 Implied vol — Delta — Gamma — Theta — Vega — Open interest 3 OI effective date Sep 10, 2026 Model this call Put · $120 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:57:40.656 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
9	6	—	—	$0.00	$4.90	$6.00		—	$32.00	$36.70	—	—	—	—
Call · $125 Daily-bar session Aug 24, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $6.00 Breakeven $131.00 Implied vol — Delta — Gamma — Theta — Vega — Open interest 9 OI effective date Sep 10, 2026 Model this call Put · $125 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:52.567 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
1	1	—	—	$0.00	$4.90	$0.85		$26.91	$37.00	$41.70	—	—	20	—
Call · $130 Daily-bar session Aug 26, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $0.85 Breakeven $130.85 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this call Put · $130 In the money Daily-bar session Aug 18, 2026 Quote as of 2026-09-11 19:57:36.679 UTC Last $26.91 Breakeven $103.09 Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
12	3	—	—	$0.00	$4.90	$0.66		—	$42.00	$46.70	—	—	—	—
Call · $135 Daily-bar session Aug 27, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $0.66 Breakeven $135.66 Implied vol — Delta — Gamma — Theta — Vega — Open interest 12 OI effective date Sep 10, 2026 Model this call Put · $135 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:41.111 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
18	1	—	—	$0.00	$4.90	$1.75		—	$47.00	$51.70	—	—	—	—
Call · $140 Daily-bar session Aug 18, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $1.75 Breakeven $141.75 Implied vol — Delta — Gamma — Theta — Vega — Open interest 18 OI effective date Sep 10, 2026 Model this call Put · $140 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:33.270 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
10	1	—	—	$0.00	$4.90	$2.75		—	$52.00	$56.70	—	—	—	—
Call · $145 Daily-bar session Aug 24, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $2.75 Breakeven $147.75 Implied vol — Delta — Gamma — Theta — Vega — Open interest 10 OI effective date Sep 10, 2026 Model this call Put · $145 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:33.270 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
3	1	—	—	$0.00	$4.90	$2.55		—	$57.00	$61.70	—	—	—	—
Call · $150 Daily-bar session Aug 19, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $2.55 Breakeven $152.55 Implied vol — Delta — Gamma — Theta — Vega — Open interest 3 OI effective date Sep 10, 2026 Model this call Put · $150 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:41.391 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
1	1	—	—	$0.00	$4.90	$2.05		$48.79	$62.00	$66.70	—	—	10	—
Call · $155 Daily-bar session Aug 19, 2026 Quote as of 2026-09-11 17:48:22.438 UTC Last $2.05 Breakeven $157.05 Implied vol — Delta — Gamma — Theta — Vega — Open interest 1 OI effective date Sep 10, 2026 Model this call Put · $155 In the money Daily-bar session Aug 18, 2026 Quote as of 2026-09-11 19:59:33.270 UTC Last $48.79 Breakeven $106.21 Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put
—	—	—	—	$0.00	$4.90	—		—	$67.00	$71.70	—	—	—	—
Call · $160 Daily-bar session Unknown Quote as of 2026-09-11 17:48:22.438 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this call Put · $160 In the money Daily-bar session Unknown Quote as of 2026-09-11 19:59:33.270 UTC Last — Breakeven — Implied vol — Delta — Gamma — Theta — Vega — Open interest — OI effective date — Model this put

About this data

Each contract's last price, day range and volume belong to the daily-bar session shown in its details; unknown means the source omitted that timestamp. Open interest has its own effective date shown separately; implied volatility and greeks are model values computed when fetched. This chain has mixed daily-bar sessions · Feb 12, 2026–Sep 11, 2026; 13 unknown. Positioning totals are shown only when every returned open-interest value has the same known effective date. Bid and ask are real-time consolidated OPRA readings.

In-the-money strikes are tinted, deepening toward the money, and the bar beside each open-interest figure scales to the heaviest strike shown. The 25 strikes around the money are shown by default — switch to "All 31" for the wings. Max pain is the listed strike where the most open interest would expire worthless — a positioning reference, not a forecast.

Key facts CIK 1636282 CUSIP 00773J202 13F (30d) 118 filings 117 filers Visit website Investor relations