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Siren, L.L.C.

Position in SYRE — Spyre Therapeutics, Inc.

CIK 2005245 New York, NY

Position in SYRE

as of Jun 30, 2026 · filed Aug 13, 2026
Position Value
$85,992,130
+$44,702,047 QoQ
Shares Held
968,598
+18.3% QoQ
Ownership
1.10%
of shares outstanding
% of Portfolio
1.75%
of 13F equity value
Holder Rank
#28
of 266 holders
Holding Since
Dec 2024
7 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in SYRE Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

Siren, L.L.C. holds $4,562,402,933 across 78 Biotechnology names. SYRE ranks #14 (1.9% of the industry book) .

# Ticker Company Shares Value (USD) Open

All Filings in SYRE

Export CSV
7 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $85,992,130 968,598
2026-03-31 $41,290,083 818,598
2025-12-31 $26,817,270 818,598
2025-09-30 $6,177,702 368,598
2025-06-30 $5,517,912 368,598
2025-03-31 $5,947,328 368,598
2024-12-31 $8,706,720 374,000