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Equibles

Venrock Adviser, LLC

Position in SYRE — Spyre Therapeutics, Inc.

CIK 1615982 NEW YORK, NY
Back to SYRE Full portfolio

Position in SYRE

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$265,048,073
+$79,154,076 QoQ
Shares Held
2,985,448
-19.0% QoQ
Ownership
3.39%
of shares outstanding
% of Portfolio
8.04%
of 13F equity value
Holder Rank
#8
of 267 holders
Holding Since
Dec 2023
11 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in SYRE Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

Venrock Adviser, LLC holds $3,294,790,938 across 31 Biotechnology names. SYRE ranks #4 (8.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 APGE
Apogee Therapeutics, Inc.
 8,493,321 $1,127,318,496
2 ORKA
Oruka Therapeutics, Inc.
 4,148,428 $394,805,892
3 ERAS
Erasca, Inc.
 17,891,812 $327,777,995
4 SYRE
Spyre Therapeutics, Inc.
This page 		2,985,448 $265,048,073
5 DNTH
Dianthus Therapeutics, Inc. /DE/
 1,180,000 $115,026,400
6 OCUL
Ocular Therapeutix, Inc
 10,346,926 $101,606,813
7 DMRA
Damora Therapeutics, Inc.
 3,603,595 $93,729,505
8 SVRA
Savara Inc
 14,745,943 $90,835,008

All Filings in SYRE

Export CSV
11 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $265,048,073 2,985,448
2026-03-31 $185,893,997 3,685,448
2025-12-31 $120,735,276 3,685,448
2025-09-30 $45,008,108 2,685,448
2025-06-30 $40,201,156 2,685,448
2025-03-31 $43,329,703 2,685,448
2024-12-31 $62,517,229 2,685,448
2024-09-30 $78,979,025 2,685,448
2024-06-30 $63,134,882 2,685,448
2024-03-31 $82,375,691 2,171,782
2023-12-31 $51,060,805 2,372,714