ELVN · Enliven Therapeutics, Inc.

$60.50 -0.37 (-0.60%) At close · Aug 27

Market Cap

$4.43B

73.27M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 211

Total Value: $4,075,825,225

Total Shares: 80,311,844

Showing 1–100 of 215 holdings by value · page 1 of 3

Institutional Ownership Trend

14 quarters

Holder Concentration

Across 211 13F filers · Δ vs Mar 31, 2026

Top Holder

12.5%

+0.0 pts

Top 5

39.3%

−2.6 pts

Top 10

55.2%

−4.6 pts

HHI

438

Broadly held−61

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +37

Institutional value: +62.4%

Shares held: +25.5%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega FMR LLC	+3,195,771	10,025,017
Mega PRICE T ROWE ASSOCIATES INC /MD/	+2,806,160	2,903,907
Large Polar Capital Holdings Plc	+1,364,703	6,430,636
Mid First Light Asset Management, LLC	+1,158,883	1,360,750
Mid Siren, L.L.C.	+1,028,185	1,774,411

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mid Venrock Adviser, LLC	−1,200,000	526,331
Mid ORBIMED ADVISORS LLC	−1,182,906	6,776,632
Large Caption Management, LLC	−906,500	50,000
Mid Bellevue Group AG	−830,867	1,490,000
Mid Logos Global Management LP	−575,000	465,000

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Large ADAGE CAPITAL PARTNERS GP, L.L.C.	1,083,313	$54,978,134
Mid SAMLYN CAPITAL, LLC	912,637	$46,316,326
Small Tri Locum Partners LP	866,716	$43,985,837
Mega Jupiter Topco LLC	604,122	$30,659,191
Large MARSHALL WACE, LLP	532,269	$27,012,651

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mid Capricorn Fund Managers Ltd	369,400	$14,480,480
Mid DV Trading LLC	95,253	$3,733,917
Mid SummitTX Capital, L.P.	68,706	$2,693,275
Mid PRELUDE CAPITAL MANAGEMENT, LLC	52,578	$2,061,057
Large Point72 Asset Management, L.P.	39,600	$1,552,320

Filter: New 61 Increased 88 Reduced 48 Sold out 24 Unchanged 14

Showing 100 of 215

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

FMR LLC

$508,769,611

12.48%

10,025,017

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	8,859,269	$449,607,901	88.4%	Defined
FIDELITY MANAGEMENT TRUST CO	61,200	$3,105,900	0.6%	Defined
STRATEGIC ADVISERS LLC	7	$355	0.0%	Defined
Fidelity Institutional Asset Management Trust Co	201,815	$10,242,111	2.0%	Defined
FIAM LLC	902,726	$45,813,344	9.0%	Defined

ORBIMED ADVISORS LLC

$343,914,074

8.44%

6,776,632

Polar Capital Holdings Plc

$326,354,777

8.01%

6,430,636

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Polar Capital LLP	6,430,636	$326,354,777	100.0%	Defined

BlackRock, Inc.

$221,254,972

5.43%

4,359,704

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	61,208	$3,106,306	1.4%	Sole
BlackRock Investment Management (Australia) Ltd	157	$7,967	0.0%	Sole
BlackRock Asset Management Canada Ltd	11,092	$562,919	0.3%	Sole
BlackRock Investment Management, LLC	119,517	$6,065,487	2.7%	Sole
BLACKROCK ADVISORS LLC	217,297	$11,027,822	5.0%	Sole
BlackRock Fund Advisors	2,219,485	$112,638,863	50.9%	Sole
BlackRock Institutional Trust Company, N.A.	1,515,887	$76,931,265	34.8%	Sole
BlackRock Fund Managers Ltd.	8,365	$424,523	0.2%	Sole
BlackRock Investment Management (UK) Ltd.	34,345	$1,743,008	0.8%	Sole
BlackRock (Netherlands) B.V.	2,743	$139,207	0.1%	Sole
BlackRock Asset Management Ireland Ltd	115,497	$5,861,472	2.6%	Sole
BlackRock Asset Management Schweiz AG	7,979	$404,934	0.2%	Sole
Aperio Group, LLC	46,132	$2,341,199	1.1%	Sole

Vestal Point Capital, LP

$203,000,000

4.98%

4,000,000

Commodore Capital LP

$166,206,250

4.08%

3,275,000

PRICE T ROWE ASSOCIATES INC /MD/

$147,373,279

3.62%

2,903,907

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	71,330	$3,619,997	2.5%	Defined
Held directly	2,832,577	$143,753,282	97.5%	Sole

VANGUARD CAPITAL MANAGEMENT LLC

$130,376,851

3.20%

2,569,002

CITADEL ADVISORS LLC

$105,001,343

2.58%

2,068,992

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	61,606	$3,126,504	3.0%	Defined
Held directly	2,007,386	$101,874,839	97.0%	Defined

Fairmount Funds Management LLC

$94,173,933

2.31%

1,855,644

Siren, L.L.C.

$90,051,358

2.21%

1,774,411

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	1,774,411	$90,051,358	100.0%	Defined

Bellevue Group AG

$75,617,500

1.86%

1,490,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BB Biotech AG joint	1,490,000	$75,617,500	100.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$71,415,501

1.75%

1,407,202

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	183,896	$9,332,722	13.1%	Defined
Held directly	1,223,306	$62,082,779	86.9%	Defined

First Light Asset Management, LLC

$69,058,062

1.69%

1,360,750

STATE STREET CORP

$61,591,012

1.51%

1,213,616

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	1,213,616	$61,591,012	100.0%	Defined

Pictet Asset Management Holding SA

$58,960,538

1.45%

1,161,784

ADAGE CAPITAL PARTNERS GP, L.L.C.

$54,978,134

1.35%

1,083,313

NOVO HOLDINGS A/S

$50,750,000

1.25%

1,000,000

First Turn Management, LLC

$48,433,770

1.19%

954,360

SAMLYN CAPITAL, LLC

$46,316,326

1.14%

912,637

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SAMLYN ONSHORE FUND, LP joint	147,171	$7,468,928	16.1%	Defined
Samlyn Offshore Master Fund, Ltd.	348,354	$17,678,965	38.2%	Defined
Samlyn Net Neutral Master Fund, Ltd.	324,245	$16,455,433	35.5%	Defined
Samlyn Long Alpha Master Fund, Ltd.	92,867	$4,713,000	10.2%	Defined

Candriam S.C.A.

$45,962,955

1.13%

905,674

BAKER BROS. ADVISORS LP

$45,938,443

1.13%

905,191

ALLIANCEBERNSTEIN L.P.

$45,480,170

1.12%

896,161

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	896,161	$45,480,170	100.0%	Defined

Tri Locum Partners LP

$43,985,837

1.08%

866,716

DIMENSIONAL FUND ADVISORS LP

$34,074,158

0.84%

671,412

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	4,223	$214,317	0.6%	Defined
DFA Australia Ltd.	14,171	$719,178	2.1%	Defined
Dimensional Ireland Ltd	28,647	$1,453,835	4.3%	Defined
Held directly	624,371	$31,686,828	93.0%	Sole

Balyasny Asset Management L.P.

$30,814,841

0.76%

607,189

Jupiter Topco LLC

$30,659,191

0.75%

604,122

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	20,974	$1,064,430	3.5%	Defined
JANUS HENDERSON INVESTORS US LLC	583,148	$29,594,761	96.5%	Defined

AMERICAN CENTURY COMPANIES INC

$28,732,873

0.70%

566,165

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	566,165	$28,732,873	100.0%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$28,560,222

0.70%

562,763

Avidity Partners Management LP

$27,912,500

0.68%

550,000

MARSHALL WACE, LLP

$27,012,651

0.66%

532,269

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	532,269	$27,012,651	100.0%	Other

Venrock Adviser, LLC

$26,711,298

0.66%

526,331

MORGAN STANLEY

$25,878,843

0.63%

509,928

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	29	$1,471	0.0%	Defined
MORGAN STANLEY & CO. LLC	248,657	$12,619,342	48.8%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	182,952	$9,284,814	35.9%	Defined
MORGAN STANLEY AIP GP LP	40,486	$2,054,664	7.9%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	4,047	$205,385	0.8%	Defined
MORGAN STANLEY SMITH BARNEY LLC	8,096	$410,872	1.6%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	25,661	$1,302,295	5.0%	Defined

Affinity Asset Advisors, LLC

$25,375,000

0.62%

500,000

SILVERARC CAPITAL MANAGEMENT, LLC

$24,836,136

0.61%

489,382

Logos Global Management LP

$23,598,750

0.58%

465,000

Rock Springs Capital Management LP

$23,579,718

0.58%

464,625

NORTHERN TRUST CORP

$22,377,601

0.55%

440,938

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	401,608	$20,381,605	91.1%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	32,699	$1,659,473	7.4%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	6,631	$336,523	1.5%	Other

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$21,540,330

0.53%

424,440

MILLENNIUM MANAGEMENT LLC

$20,876,621

0.51%

411,362

Nicholas Investment Partners, LP

$19,870,096

0.49%

391,529

ADAR1 Capital Management, LLC

$19,676,688

0.48%

387,718

VANGUARD FIDUCIARY TRUST CO

$19,462,117

0.48%

383,490

Nuveen, LLC

$18,991,512

0.47%

374,217

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	14,724	$747,243	3.9%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	32,630	$1,655,972	8.7%	Defined
TEACHERS ADVISORS, LLC joint	326,863	$16,588,297	87.3%	Defined

Seven Fleet Capital Management LP

$18,543,339

0.45%

365,386

Woodline Partners LP

$17,617,456

0.43%

347,142

STEMPOINT CAPITAL LP

$17,605,885

0.43%

346,914

UBS Group AG

$17,362,335

0.43%

342,115

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	100	$5,075	0.0%	Defined
UBS AG	340,362	$17,273,371	99.5%	Defined
UBS Switzerland AG	1,653	$83,889	0.5%	Defined

LORD, ABBETT & CO. LLC

$16,786,019

0.41%

330,759

Spruce Street Capital LP

$16,697,054

0.41%

329,006

GOLDMAN SACHS GROUP INC

$16,349,416

0.40%

322,156

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	278,673	$14,142,654	86.5%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	43,483	$2,206,762	13.5%	Defined

Longaeva Partners L.P.

$15,862,420

0.39%

312,560

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Balyasny Asset Management L.P.	312,560	$15,862,420	100.0%	Other

JENNISON ASSOCIATES LLC

$15,692,864

0.39%

309,219

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	309,219	$15,692,864	100.0%	Defined

Assenagon Asset Management S.A.

$15,558,630

0.38%

306,574

D. E. Shaw & Co., Inc.

$15,514,427

0.38%

305,703

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	305,703	$15,514,427	100.0%	Defined

T. Rowe Price Investment Management, Inc.

$15,270,218

0.37%

300,891

TimesSquare Capital Management, LLC

$13,263,208

0.33%

261,344

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GuideStone Capital Management, LLC joint	261,344	$13,263,208	100.0%	Sole

AMERIPRISE FINANCIAL INC

$12,747,994

0.31%

251,192

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	246,676	$12,518,807	98.2%	Defined
Columbia Threadneedle Management Ltd	4,516	$229,187	1.8%	Defined

Deep Track Capital, LP

$11,418,750

0.28%

225,000

Blackstone Inc.

$10,949,008

0.27%

215,744

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Blackstone Alternative Asset Management L.P.	215,744	$10,949,008	100.0%	Other

NEUBERGER BERMAN GROUP LLC

$10,877,907

0.27%

214,343

Patient Square Capital LP

$10,784,375

0.26%

212,500

Soleus Capital Management, L.P.

$8,408,107

0.21%

165,677

Connor, Clark & Lunn Investment Management Ltd.

$8,164,608

0.20%

160,879

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	158,522	$8,044,991	98.5%	Sole
Held directly	2,357	$119,617	1.5%	Sole

Squadron Capital Management LLC

$8,120,000

0.20%

160,000

Integral Health Asset Management, LLC

$7,612,500

0.19%

150,000

Cormorant Asset Management, LP

$7,612,500

0.19%

150,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Chen Bihua	150,000	$7,612,500	100.0%	Defined

HighVista Strategies LLC

$6,996,699

0.17%

137,866

Eversept Partners, LP

$6,934,023

0.17%

136,631

WELLINGTON MANAGEMENT GROUP LLP

$6,757,004

0.17%

133,143

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	65,174	$3,307,580	49.0%	Defined
Wellington Managment Canada LLC	417	$21,162	0.3%	Defined
Wellington Management International Ltd	66	$3,349	0.0%	Defined
Wellington Trust Company, NA joint	61,408	$3,116,456	46.1%	Defined
Wellington Management Australia Pty Ltd	5,125	$260,093	3.8%	Defined
Wellington Management Europe GmbH	953	$48,364	0.7%	Defined

Ikarian Capital, LLC

$6,421,955

0.16%

126,541

Bank of New York Mellon Corp

$6,031,788

0.15%

118,853

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	34,811	$1,766,658	29.3%	Defined
The Bank of New York Mellon	83,233	$4,224,074	70.0%	Defined
BNY Mellon, NA joint	808	$41,006	0.7%	Defined
Held directly	1	$50	0.0%	Defined

Invesco Ltd.

$5,733,328

0.14%

112,972

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	6,759	$343,019	6.0%	Defined
Invesco Trust Co joint	17,002	$862,851	15.0%	Defined
Invesco Capital Management LLC	89,211	$4,527,458	79.0%	Defined

SPHERA FUNDS MANAGEMENT LTD.

$5,722,823

0.14%

112,765

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	112,765	$5,722,823	100.0%	Defined

J. Goldman & Co LP

$5,690,546

0.14%

112,129

TD Asset Management Inc

$5,569,203

0.14%

109,738

Cinctive Capital Management LP

$5,465,166

0.13%

107,688

Exome Asset Management LLC

$5,085,302

0.12%

100,203

BANK OF AMERICA CORP /DE/

$4,974,667

0.12%

98,023

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	78,375	$3,977,531	80.0%	Defined
BOFA SECURITIES, INC.	14,316	$726,537	14.6%	Defined
MANAGED ACCOUNT ADVISORS LLC	5,332	$270,599	5.4%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$4,892,300

0.12%

96,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	96,400	$4,892,300	100.0%	Other

Swiss National Bank

$4,799,579

0.12%

94,573

Russell Investments Group, Ltd.

$4,665,852

0.11%

91,938

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	46,234	$2,346,375	50.3%	Defined
Russell Investments Capital, LLC	22,859	$1,160,094	24.9%	Defined
Russell Investments France SAS	8,147	$413,460	8.9%	Defined
Russell Investments Trust Company	14,698	$745,923	16.0%	Defined

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$4,063,651

0.10%

80,072

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	677	$34,357	0.8%	Defined
UBS Asset Management Switzerland AG	55,009	$2,791,706	68.7%	Defined
UBS Asset Management (UK) Ltd.	18,569	$942,376	23.2%	Sole
Held directly	5,817	$295,212	7.3%	Defined

DV EQUITIES, LLC

$3,869,687

0.09%

76,250

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$3,819,698

0.09%

75,265

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	75,265	$3,819,698	100.0%	Defined

VOYA INVESTMENT MANAGEMENT LLC

$3,778,489

0.09%

74,453

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	74,453	$3,778,489	100.0%	Defined

Artia Global Partners LP

$3,659,075

0.09%

72,100

ALGERT GLOBAL LLC

$3,658,567

0.09%

72,090

CITADEL ADVISORS LLC

$3,654,000

0.09%

72,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	72,000	$3,654,000	100.0%	Defined

Informed Momentum Co LLC

$3,574,424

0.09%

70,432

SEVEN GRAND MANAGERS, LLC

$3,552,500

0.09%

70,000

GREAT POINT PARTNERS LLC

$3,552,500

0.09%

70,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JAY JEFFREY R joint	70,000	$3,552,500	100.0%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$3,407,913

0.08%

67,151

Tidal Investments LLC

$3,080,220

0.08%

60,694

Tema ETFs LLC

$3,080,220

0.08%

60,694

RHUMBLINE ADVISERS

$2,904,980

0.07%

57,241

Schonfeld Strategic Advisors LLC

$2,836,113

0.07%

55,884

Atom Investors LP

$2,543,691

0.06%

50,122

Caption Management, LLC

$2,537,500

0.06%

50,000

Jones Hill Capital LP

$2,529,887

0.06%

49,850

Key facts CIK 1672619 CUSIP 29337E102 13F (30d) 195 filings 194 filers Visit website Investor relations