GREAT POINT PARTNERS LLC
Filing Date
Global Rank
#2,769
/ 8,700
▲ 1099
Top Industry
Biotechnology
94.9%
Period ended 2 months ago
Filed Aug 14, 2026 · 30d
26 quarters · since Mar 2020
Portfolio Concentration
41 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026Top Position
15.2%
+7.8 pts
Top 5
35.7%
+3.6 pts
Top 10
55.4%
+1.2 pts
HHI
504
Diversified+106
Portfolio Trend
26 quarters · across all stocks
Sector Breakdown
As of Jun 30, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 98.0% | $518,359,388 |
| Financial Services | 2.0% | $10,760,000 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
7 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| IRD | Opus Genetics, Inc. | +1,645,847 | 1,970,187 | $8,097,468 | |
| ANNX | Annexon, Inc. | +1,000,000 | 3,500,000 | $19,985,000 | |
| IMMX | Immix Biopharma, Inc. | +927,642 | 1,277,642 | $13,172,489 | |
| VERA | Vera Therapeutics, Inc. | +401,488 | 600,836 | $25,781,872 | |
| MLTX | MoonLake Immunotherapeutics | +355,813 | 855,813 | $16,662,679 | |
| CTNM | Contineum Therapeutics, Inc. | +121,283 | 921,481 | $15,103,073 | |
| LBRX | Lb Pharmaceuticals Inc | +17,221 | 317,221 | $10,295,407 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
10 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| SCYX | Scynexis Inc | −6,610,055 | 944,292 | $3,843,268 | |
| PALI | Palisade Bio, Inc. | −1,120,938 | 2,284,819 | $4,775,271 | |
| AMLX | Amylyx Pharmaceuticals, Inc. | −1,050,000 | 700,000 | $12,572,000 | |
| SLN | Silence Therapeutics plc | −570,489 | 450,000 | $4,941,000 | |
| CLYM | Climb Bio, Inc. | −334,130 | 1,000,000 | $13,040,000 | |
| PMN | ProMIS Neurosciences Inc. | −285,252 | 86,150 | $1,133,734 | |
| NGNE | Neurogene Inc. | −147,820 | 352,180 | $11,076,061 | |
| NKTR | Nektar Therapeutics | −141,453 | 175,000 | $12,216,750 | |
| DRUG | Bright Minds Biosciences Inc. | −110,397 | 109,603 | $7,694,130 | |
| VOR | Vor Biopharma Inc. | −50,000 | 1,700,000 | $31,297,000 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
11 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| ABVX | Abivax S.A. | 604,314 | $80,530,883 | |
| RARE | Ultragenyx Pharmaceutical Inc. | 600,000 | $20,034,000 | |
| DFTX | Definium Therapeutics, Inc. | 425,000 | $19,992,000 | |
| SGMT | Sagimet Biosciences Inc. | 2,029,933 | $15,691,382 | |
| IFRX | InflaRx N.V. | 3,046,557 | $6,824,287 | |
| JATT | JATT II Acquisition Corp. | 500,000 | $5,680,000 | |
| ALT | Altimmune, Inc. | 1,741,232 | $5,293,345 | |
| AMAN | Amanat Acquisition Corp. | 500,000 | $5,080,000 | |
| ELVN | Enliven Therapeutics, Inc. | 70,000 | $3,552,500 | |
| RNTX | Rein Therapeutics, Inc. | 2,575,000 | $2,678,000 | |
| DBVT | DBV Technologies S.A. | 156,906 | $2,573,258 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
12 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| APGE | Apogee Therapeutics, Inc. | 374,000 | $31,479,580 | |
| IMVT | Immunovant, Inc. | 545,625 | $13,553,325 | |
| JBIO | Jade Biosciences, Inc. | 964,462 | $13,550,691 | |
| ZBIO | Zenas BioPharma, Inc. | 524,066 | $10,245,490 | |
| CMPX | Compass Therapeutics, Inc. | 1,350,000 | $7,141,500 | |
| CNTX | Context Therapeutics Inc. | 2,238,496 | $5,864,859 | |
| UNCY | Unicycive Therapeutics, Inc. | 796,558 | $5,241,351 | |
| TENX | Tenax Therapeutics, Inc. | 327,307 | $5,233,638 | |
| PHVS | Pharvaris N.V. | 82,800 | $2,339,100 | |
| AVTX | Avalo Therapeutics, Inc. | 124,666 | $1,861,263 | |
| ALKS | Alkermes plc. | 50,000 | $1,768,000 | |
| — | 675,000 | $0 | ||
| No positions match the current search. | ||||
41 tracked positions ·
$529,119,388 total
· filing declares
42 positions · $529,120,900
· as of Jun 30, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| ABVX |
Abivax S.A.
CALL
+ SHARES
Healthcare
|
NEW | 604,314 | $80,530,883 | 15.22% | |
| VOR |
Vor Biopharma Inc.
Healthcare
|
Reduced | 1,700,000 | $31,297,000 | 5.91% | |
| IBRX |
ImmunityBio, Inc.
PUT
Healthcare
|
Held | 3,000,800 | $26,272,004 | 4.97% | |
| VERA |
Vera Therapeutics, Inc.
Healthcare
|
Added | 600,836 | $25,781,872 | 4.87% | |
| ZURA |
Zura Bio Ltd
Healthcare
|
Held | 4,215,930 | $24,873,987 | 4.70% | |
| ALMS |
Alumis Inc.
Healthcare
|
Held | 856,061 | $24,089,556 | 4.55% | |
| SLGL |
Sol-Gel Technologies Ltd.
Healthcare
|
Held | 274,363 | $20,341,272 | 3.84% | |
| RARE |
Ultragenyx Pharmaceutical Inc.
PUT
Healthcare
|
NEW | 600,000 | $20,034,000 | 3.79% | |
| DFTX |
Definium Therapeutics, Inc.
Healthcare
|
NEW | 425,000 | $19,992,000 | 3.78% | |
| ANNX |
Annexon, Inc.
Healthcare
|
Added | 3,500,000 | $19,985,000 | 3.78% | |
| ORKA |
Oruka Therapeutics, Inc.
Healthcare
|
Held | 183,330 | $17,447,516 | 3.30% | |
| MLTX |
MoonLake Immunotherapeutics
Healthcare
|
Added | 855,813 | $16,662,679 | 3.15% | |
| SGMT |
Sagimet Biosciences Inc.
Healthcare
|
NEW | 2,029,933 | $15,691,382 | 2.97% | |
| CTNM |
Contineum Therapeutics, Inc.
Healthcare
|
Added | 921,481 | $15,103,073 | 2.85% | |
| IMMX |
Immix Biopharma, Inc.
Healthcare
|
Added | 1,277,642 | $13,172,489 | 2.49% | |
| CLYM |
Climb Bio, Inc.
Healthcare
|
Reduced | 1,000,000 | $13,040,000 | 2.46% | |
| AMLX |
Amylyx Pharmaceuticals, Inc.
Healthcare
|
Reduced | 700,000 | $12,572,000 | 2.38% | |
| NKTR |
Nektar Therapeutics
Healthcare
|
Reduced | 175,000 | $12,216,750 | 2.31% | |
| NGNE |
Neurogene Inc.
Healthcare
|
Reduced | 352,180 | $11,076,061 | 2.09% | |
| LBRX |
Lb Pharmaceuticals Inc
Healthcare
|
Added | 317,221 | $10,295,407 | 1.95% | |
| IRD |
Opus Genetics, Inc.
Healthcare
|
Added | 1,970,187 | $8,097,468 | 1.53% | |
| EPRX |
Eupraxia Pharmaceuticals Inc.
Healthcare
|
Held | 1,200,000 | $7,932,000 | 1.50% | |
| DRUG |
Bright Minds Biosciences Inc.
Healthcare
|
Reduced | 109,603 | $7,694,130 | 1.45% | |
| IFRX |
InflaRx N.V.
Healthcare
|
NEW | 3,046,557 | $6,824,287 | 1.29% | |
| RLMD |
Relmada Therapeutics, Inc.
Healthcare
|
Held | 842,106 | $5,827,373 | 1.10% | |
| JATT |
JATT II Acquisition Corp.
Financial Services
|
NEW | 500,000 | $5,680,000 | 1.07% | |
| CGEM |
Cullinan Therapeutics, Inc.
Healthcare
|
Held | 300,000 | $5,463,000 | 1.03% | |
| ALT |
Altimmune, Inc.
Healthcare
|
NEW | 1,741,232 | $5,293,345 | 1.00% | |
| AMAN |
Amanat Acquisition Corp.
Financial Services
|
NEW | 500,000 | $5,080,000 | 0.96% | |
| RZLT |
Rezolute, Inc.
Healthcare
|
Held | 951,809 | $4,949,406 | 0.94% | |
| SLN |
Silence Therapeutics plc
Healthcare
|
Reduced | 450,000 | $4,941,000 | 0.93% | |
| PALI |
Palisade Bio, Inc.
Healthcare
|
Reduced | 2,284,819 | $4,775,271 | 0.90% | |
| EVMN |
Evommune, Inc.
Healthcare
|
Held | 325,000 | $4,319,250 | 0.82% | |
| SCYX |
Scynexis Inc
Healthcare
|
Reduced | 944,292 | $3,843,268 | 0.73% | |
| GALT |
Galectin Therapeutics Inc
CALL
Healthcare
|
Held | 800,000 | $3,712,000 | 0.70% | |
| ELVN |
Enliven Therapeutics, Inc.
Healthcare
|
NEW | 70,000 | $3,552,500 | 0.67% | |
| HUMA |
Humacyte, Inc.
Healthcare
|
Held | 3,750,000 | $2,925,000 | 0.55% | |
| RNTX |
Rein Therapeutics, Inc.
Healthcare
|
NEW | 2,575,000 | $2,678,000 | 0.51% | |
| DBVT |
DBV Technologies S.A.
Healthcare
|
NEW | 156,906 | $2,573,258 | 0.49% | |
| AVXL |
Anavex Life Sciences Corp.
CALL
Healthcare
|
Held | 521,300 | $1,350,167 | 0.26% | |
| PMN |
ProMIS Neurosciences Inc.
Healthcare
|
Reduced | 86,150 | $1,133,734 | 0.21% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.