NGNE · Neurogene Inc.

$38.41 -2.43 (-5.95%) At close · Aug 26

Market Cap

$784.55M

20.01M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 112

Total Value: $548,670,809

Total Shares: 17,445,815

Institutional Ownership Trend

13 quarters

Holder Concentration

Across 112 13F filers · Δ vs Mar 31, 2026

Top Holder

9.8%

−0.2 pts

Top 5

41.9%

−0.2 pts

Top 10

66.3%

−0.1 pts

HHI

528

Broadly held−15

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +14

Institutional value: +58.5%

Shares held: +1.6%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mid Casdin Capital, LLC	+125,000	1,545,361
Large Driehaus Capital Management LLC	+110,763	143,528
Large Balyasny Asset Management L.P.	+100,317	818,706
Mega BlackRock, Inc.	+52,913	1,057,983
Small DAFNA Capital Management LLC	+32,397	89,032

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mid ArrowMark Colorado Holdings LLC	−182,343	342,453
Mega MILLENNIUM MANAGEMENT LLC	−162,075	42,734
Small GREAT POINT PARTNERS LLC	−147,820	352,180
Mega MORGAN STANLEY	−93,515	191,724
Mega STATE STREET CORP	−88,683	224,322

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mega FRANKLIN RESOURCES INC	204,280	$6,424,605
Large Point72 Asset Management, L.P.	141,920	$4,463,384
Mid MOORE CAPITAL MANAGEMENT, LP	141,636	$4,454,452
Large Trexquant Investment LP	73,762	$2,319,814
Mega WELLINGTON MANAGEMENT GROUP LLP	31,393	$987,308

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mega TWO SIGMA INVESTMENTS, LP	13,891	$280,042
Large NOMURA HOLDINGS INC	12,724	$256,515
Large CWM, LLC	1,030	$20,764
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	604	$12,176
Mid SIMPLEX TRADING, LLC	89	$1,794

Filter: New 21 Increased 39 Reduced 31 Sold out 7 Unchanged 21

Showing 100 of 114

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

SAMSARA BIOCAPITAL, LLC

$54,003,644

9.84%

1,717,127

Casdin Capital, LLC

$48,601,603

8.86%

1,545,361

Redmile Group, LLC

$44,413,658

8.09%

1,412,199

RTW INVESTMENTS, LP

$42,849,241

7.81%

1,362,456

EcoR1 Capital, LLC

$39,983,705

7.29%

1,271,342

BlackRock, Inc.

$33,273,561

6.06%

1,057,983

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	4,706	$148,003	0.4%	Sole
BlackRock Asset Management Canada Ltd	103	$3,239	0.0%	Sole
BlackRock Investment Management, LLC	33,346	$1,048,731	3.2%	Sole
BLACKROCK ADVISORS LLC	60,831	$1,913,134	5.7%	Sole
BlackRock Fund Advisors	534,591	$16,812,886	50.5%	Sole
BlackRock Institutional Trust Company, N.A.	394,296	$12,400,609	37.3%	Sole
BlackRock Asset Management Ireland Ltd	10,832	$340,666	1.0%	Sole
Aperio Group, LLC	19,278	$606,293	1.8%	Sole

BAKER BROS. ADVISORS LP

$31,188,681

5.68%

991,691

Balyasny Asset Management L.P.

$25,748,303

4.69%

818,706

Trails Edge Capital Partners, LP

$22,483,133

4.10%

714,885

TORONTO DOMINION BANK

$21,428,048

3.91%

681,337

VANGUARD CAPITAL MANAGEMENT LLC

$16,873,711

3.08%

536,525

JENNISON ASSOCIATES LLC

$16,309,403

2.97%

518,582

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	518,582	$16,309,403	100.0%	Defined

CITADEL ADVISORS LLC

$12,862,483

2.34%

408,982

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	258,034	$8,115,169	63.1%	Defined
Held directly	150,948	$4,747,314	36.9%	Defined

GREAT POINT PARTNERS LLC

$11,076,061

2.02%

352,180

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JAY JEFFREY R joint	352,180	$11,076,061	100.0%	Defined

ArrowMark Colorado Holdings LLC

$10,770,146

1.96%

342,453

FMR LLC

$9,295,393

1.69%

295,561

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	295,561	$9,295,393	100.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$9,220,573

1.68%

293,182

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	41,218	$1,296,306	14.1%	Defined
Held directly	251,964	$7,924,267	85.9%	Defined

STATE STREET CORP

$7,054,926

1.29%

224,322

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	224,322	$7,054,926	100.0%	Defined

FRANKLIN RESOURCES INC

$6,424,605

1.17%

204,280

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST INTERNATIONAL LLC	46	$1,446	0.0%	Defined
FRANKLIN ADVISERS INC	204,234	$6,423,159	100.0%	Defined

MORGAN STANLEY

$6,029,717

1.10%

191,724

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	1	$31	0.0%	Defined
MORGAN STANLEY & CO. LLC	3,595	$113,062	1.9%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	183,952	$5,785,290	95.9%	Defined
MORGAN STANLEY SMITH BARNEY LLC	2,325	$73,121	1.2%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	1,851	$58,213	1.0%	Defined

UBS Group AG

$5,387,038

0.98%

171,289

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	62	$1,949	0.0%	Defined
UBS AG	171,227	$5,385,089	100.0%	Defined

BLAIR WILLIAM & CO/IL

$4,620,162

0.84%

146,905

Driehaus Capital Management LLC

$4,513,955

0.82%

143,528

Point72 Asset Management, L.P.

$4,463,384

0.81%

141,920

MOORE CAPITAL MANAGEMENT, LP

$4,454,452

0.81%

141,636

Rock Springs Capital Management LP

$3,357,287

0.61%

106,750

DEUTSCHE BANK AG\

$3,354,456

0.61%

106,660

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	12,948	$407,214	12.1%	Defined
DWS Investments UK Ltd	93,712	$2,947,242	87.9%	Defined

NORTHERN TRUST CORP

$3,259,508

0.59%

103,641

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	95,532	$3,004,481	92.2%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	6,333	$199,172	6.1%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	1,776	$55,855	1.7%	Other

GOLDMAN SACHS GROUP INC

$3,185,129

0.58%

101,276

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	62,948	$1,979,714	62.2%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	38,328	$1,205,415	37.8%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$3,006,651

0.55%

95,601

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$2,905,980

0.53%

92,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	92,400	$2,905,980	100.0%	Other

DAFNA Capital Management LLC

$2,800,056

0.51%

89,032

Woodline Partners LP

$2,636,610

0.48%

83,835

VANGUARD FIDUCIARY TRUST CO

$2,335,539

0.43%

74,262

Trexquant Investment LP

$2,319,814

0.42%

73,762

JPMORGAN CHASE & CO

$1,946,187

0.35%

61,882

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	8,511	$267,670	13.8%	Defined
J.P. Morgan Investment Management Inc.	52,051	$1,637,003	84.1%	Defined
J.P. Morgan Securities plc	1,320	$41,514	2.1%	Defined

XTX Topco Ltd

$1,743,084

0.32%

55,424

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	55,424	$1,743,084	100.0%	Defined

SCHRODER INVESTMENT MANAGEMENT GROUP

$1,644,835

0.30%

52,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	52,300	$1,644,835	100.0%	Sole

MILLENNIUM MANAGEMENT LLC

$1,343,984

0.24%

42,734

Raiffeisen Bank International AG

$1,069,300

0.19%

34,000

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$1,029,735

0.19%

32,742

DIMENSIONAL FUND ADVISORS LP

$1,026,150

0.19%

32,628

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DFA Australia Ltd.	820	$25,789	2.5%	Defined
Dimensional Ireland Ltd	212	$6,667	0.6%	Defined
Held directly	31,596	$993,694	96.8%	Sole

WELLINGTON MANAGEMENT GROUP LLP

$987,308

0.18%

31,393

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	9,926	$312,172	31.6%	Defined
Wellington Trust Company, NA joint	19,941	$627,144	63.5%	Defined
Wellington Management Australia Pty Ltd	1,526	$47,992	4.9%	Defined

Bank of New York Mellon Corp

$903,903

0.16%

28,741

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	10,789	$339,314	37.5%	Defined
The Bank of New York Mellon	17,914	$563,395	62.3%	Defined
BNY Mellon, NA joint	35	$1,100	0.1%	Defined
Held directly	3	$94	0.0%	Defined

Nuveen, LLC

$875,064

0.16%

27,824

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	3,967	$124,762	14.3%	Defined
TEACHERS ADVISORS, LLC joint	23,857	$750,302	85.7%	Defined

CITADEL ADVISORS LLC

$839,715

0.15%

26,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	26,700	$839,715	100.0%	Defined

JANE STREET GROUP, LLC

$820,498

0.15%

26,089

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	22,377	$703,756	85.8%	Defined
Jane Street Global Trading, LLC	3,712	$116,742	14.2%	Defined

Quadrature Capital Ltd

$764,864

0.14%

24,320

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	24,320	$764,864	100.0%	Other

AMERICAN CENTURY COMPANIES INC

$733,728

0.13%

23,330

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	23,330	$733,728	100.0%	Defined

Seven Fleet Capital Management LP

$693,787

0.13%

22,060

RENAISSANCE TECHNOLOGIES LLC

$641,737

0.12%

20,405

BRIDGEWAY CAPITAL MANAGEMENT, LLC

$590,662

0.11%

18,781

ALPS ADVISORS INC

$504,458

0.09%

16,040

AQR CAPITAL MANAGEMENT LLC

$473,665

0.09%

15,061

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	3	$94	0.0%	Other
Prism Planning Partners LLC	23	$723	0.2%	Other
Compound Planning, Inc.	6	$188	0.0%	Other
Arax Advisory Partners	798	$25,097	5.3%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	143	$4,497	0.9%	Other
Stokes Family Office, LLC	6	$188	0.0%	Other
Held directly	14,082	$442,878	93.5%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$462,315

0.08%

14,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	14,700	$462,315	100.0%	Other

RHUMBLINE ADVISERS

$445,111

0.08%

14,153

LOS ANGELES CAPITAL MANAGEMENT LLC

$434,104

0.08%

13,803

ALLIANCEBERNSTEIN L.P.

$433,066

0.08%

13,770

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	13,770	$433,066	100.0%	Defined

Mariner, LLC

$385,577

0.07%

12,260

Virtus Investment Advisers, LLC

$353,623

0.06%

11,244

BANK OF AMERICA CORP /DE/

$349,849

0.06%

11,124

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	11,124	$349,849	100.0%	Defined

Creative Planning

$332,772

0.06%

10,581

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	94	$2,956	0.9%	Defined
Held directly	10,487	$329,816	99.1%	Sole

D. E. Shaw & Co., Inc.

$307,612

0.06%

9,781

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	9,781	$307,612	100.0%	Defined

WELLS FARGO & COMPANY/MN

$297,862

0.05%

9,471

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	9,471	$297,862	100.0%	Defined

Pale Fire Capital SE

$297,517

0.05%

9,460

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Barta Jan joint	9,460	$297,517	100.0%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$279,779

0.05%

8,896

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	8,896	$279,779	100.0%	Defined

Brevan Howard Capital Management LP

$263,771

0.05%

8,387

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Brevan Howard US Investment Management, LP	8,387	$263,771	100.0%	Defined

CITIGROUP INC

$247,447

0.05%

7,868

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	7,868	$247,447	100.0%	Defined

ADAR1 Capital Management, LLC

$245,310

0.04%

7,800

STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM

$235,591

0.04%

7,491

Invesco Ltd.

$209,392

0.04%

6,658

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	1,373	$43,180	20.6%	Defined
Invesco Trust Co joint	4,486	$141,084	67.4%	Defined
Invesco Capital Management LLC	799	$25,128	12.0%	Defined

Mitsubishi UFJ Asset Management Co., Ltd.

$191,530

0.03%

6,090

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MITSUBISHI UFJ FINANCIAL GROUP INC	6,090	$191,530	100.0%	Defined

Russell Investments Group, Ltd.

$188,385

0.03%

5,990

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	5,990	$188,385	100.0%	Defined

MetLife Investment Management, LLC

$186,561

0.03%

5,932

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	5,932	$186,561	100.0%	Defined

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$163,760

0.03%

5,207

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	5,207	$163,760	100.0%	Defined

Vanguard Global Advisers, LLC

$152,658

0.03%

4,854

PNC FINANCIAL SERVICES GROUP, INC.

$141,555

0.03%

4,501

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	4,501	$141,555	100.0%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$132,090

0.02%

4,200

Police & Firemen's Retirement System of New Jersey

$120,956

0.02%

3,846

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	3,846	$120,956	100.0%	Defined

NATIXIS

$117,025

0.02%

3,721

BARCLAYS PLC

$104,099

0.02%

3,310

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	3,074	$96,677	92.9%	Defined
BARCLAYS CAPITAL INC.	236	$7,422	7.1%	Defined

China Universal Asset Management Co., Ltd.

$79,096

0.01%

2,515

ROYAL BANK OF CANADA

$75,667

0.01%

2,406

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	344	$10,818	14.3%	Defined
RBC Capital Markets, LLC	2,062	$64,849	85.7%	Defined

BNP PARIBAS ARBITRAGE, SA

$59,692

0.01%

1,898

Legal & General Group Plc

$34,532

0.01%

1,098

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	1,098	$34,532	100.0%	Defined

Ameritas Investment Partners, Inc.

$31,733

0.01%

1,009

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	1,009	$31,733	100.0%	Other

State of Wyoming

$30,821

0.01%

980

Arax Advisory Partners

$28,493

0.01%

906

Mirae Asset Global Investments Co., Ltd.

$22,235

0.00%

707

GAMMA Investing LLC

$17,140

0.00%

545

NISA INVESTMENT ADVISORS, LLC

$14,561

0.00%

463

Tower Research Capital LLC (TRC)

$13,838

0.00%

440

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	440	$13,838	100.0%	Defined

GF FUND MANAGEMENT CO. LTD.

$10,441

0.00%

332

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$9,183

0.00%

292

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	292	$9,183	100.0%	Defined

Rockefeller Capital Management L.P.

$7,264

0.00%

231

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER TRUST COMPANY, N.A.	231	$7,264	100.0%	Defined

Sterling Capital Management LLC

$7,170

0.00%

228

Farther Finance Advisors, LLC

$5,535

0.00%

176

US BANCORP \DE\

$4,623

0.00%

147

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
US BANK NATIONAL ASSOCIATION	147	$4,623	100.0%	Defined

SBI Securities Co., Ltd.

$3,931

0.00%

125

Integrated Wealth Concepts LLC

$3,302

0.00%

105

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Optiver VOF	32	$1,006	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMSS Wesson Wealth Solutions, LLC	4	$125	14.7%	Sole
Held directly	23	$723	85.3%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
National Bank Financial Inc.	8	$251	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA SECURITIES INTERNATIONAL INC	12,724	$256,515	100.0%	Defined

Key facts CIK 1404644 CUSIP 64135M105 13F (30d) 105 filings 102 filers Visit website Investor relations