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TSHA · Taysha Gene Therapies, Inc. · Holdings

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$4.25 +0.24 (+5.99%) At close · Oct 27 Q2 2026 earnings call transcript
Russell 2000 member Rebalance outlook locked
Market Cap
$1.36B
Shares
325.83M
Volume · Oct 27 2.82M Avg daily vol (3M) 3.55M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP → See every holder of TSHA: 13F, 13D and 13G, insiders and funds →
The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.
Holders: 211
Total Value: $2,043,473,574
Total Shares: 300,507,669
Showing 1–100 of 216 holdings by value · page 1 of 3

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 208 13F filers
Top Holder
8.0%
Sep 2023 → Jun 2026 · range 8.0% – 18.8%
of institutional value
Top 5
36.7%
Sep 2023 → Jun 2026 · range 36.4% – 65.6%
of institutional value
Top 10
59.1%
Sep 2023 → Jun 2026 · range 59.1% – 81.0%
of institutional value
HHI
424
Sep 2023 → Jun 2026 · range 424 – 991
Broadly held

Who Holds TSHA

Last 8 quarters through Sep 30, 2026 (filing window open)

Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.

Jun 30, 2026, the newest closed quarter: 208 filers, like-for-like change +11.9%; actively managed books +14.4%; index-like books +7.4%.

Holder type Share Filers Change
Registered adviser 53.3% 105 +11.5%
Exempt adviser 0.2% 3 +5498.3%
Adviser 2.0% 7 +344.0%
Bank 6.5% 14 -1.4%
Insurer 0.0% 3 +53.6%
Broker-dealer 0.0% 1 new
Benefit plan 0.1% 4 +1.0%
Non-US 2.5% 9 -7.5%
Holding company 26.7% 10 +6.2%
Unknown 8.7% 52 +29.6%

The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.

How the mix is measured

Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.

Excluded 1 holder with no observed 2026-03-31 13F and 1 holder with no observed 2026-06-30 13F. Compared across CIK changes: JANUS HENDERSON GROUP PLC continues as Jupiter Topco LLC.

Conviction and Crowding

208 13F filers, quarter ended Jun 30, 2026

Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.

Conviction holders
4
1.92% of filers hold it in their top 10
Mar 31, 2026: 2
Holders above 5%
2
median weight 0.002%
Mar 31, 2026: 1
Crowding
—
holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice
Mar 31, 2026: 43.0%
Private-fund advisers
—
of shares outstanding
Institutional ownership
—
holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice
Top 10 holders
59.3%
of 13F shares, Herfindahl 0.043
Active holders
+14.4%
like-for-like share change of active filers
5% stakes on record
8
1 13D, 7 13G (5 institutional, 2 passive, 0 exempt)
How long holders have held it value-weighted 10.8 quarters
Under 1 year 18.5% 1 to 3 years 38.8% 3 years or more 42.7% Since coverage start 0.000%

Managers in the top fifth by current three-year FundScore alpha were net buyers of $3,092,555 (1 buying, 0 selling).

Estimated Holder Cost Basis

Quarter ended Jun 30, 2026, on that quarter's share basis

Estimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.

Estimated avg cost
$3.36
estimated per share
Mar 31, 2026: $2.88
Quarter-end price
$6.81
implied by 13F values
Estimated gain or loss
+102.6%
price against the estimated cost
Estimated at a loss
0.000%
of costed 13F value

Estimated cost covers 75.5% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.

Shared Holders

Companies TSHA's active holders also own, quarter ended Jun 30, 2026
# Company Shared holders
1 IRON Disc Medicine, Inc. 11
2 PRLD Prelude Therapeutics Inc 5
3 LXEO Lexeo Therapeutics, Inc. 7
4 XENE Xenon Pharmaceuticals Inc. 13
5 BIOA BioAge Labs, Inc. 9
6 EWTX Edgewise Therapeutics, Inc. 10
7 QURE uniQure N.V. 13
8 RLAY Relay Therapeutics, Inc. 10
9 AVTX Avalo Therapeutics, Inc. 10
10 CRNX Crinetics Pharmaceuticals, Inc. 9

Shareholder Targets

13F filers that own its peers but not TSHA, quarter ended Jun 30, 2026

Found through its holder-overlap peers: IRON, PRLD, LXEO, XENE, BIOA, EWTX, QURE, RLAY, AVTX, CRNX, GPCR, VYGR, MNPR, PALI, FDMT, FTH, SGP, SYRE, ZLAB, APRE. 551 filers in all.

# Filer In peers
1 Driehaus Capital Management LLC Registered adviser, Diversified active $1,040,346,613 6 held
2 PERCEPTIVE ADVISORS LLC Registered adviser, Diversified active $854,534,784 6 held
3 Paradigm Biocapital Advisors LP Registered adviser, Concentrated $775,474,609 3 held
4 TCG Crossover Management, LLC Unknown, Diversified active $538,029,281 6 held
5 SB INVESTMENT ADVISERS (UK) LTD Registered adviser, Concentrated $522,101,857 1 held
6 BVF INC/IL Unknown, Concentrated $341,723,185 4 held
7 NOVO HOLDINGS A/S Unknown, Concentrated $339,280,004 4 held
8 Deep Track Capital, LP Adviser, Diversified active $321,112,464 2 held
9 Commodore Capital LP Registered adviser, Concentrated $318,516,196 3 held
10 BRAIDWELL LP Registered adviser, Diversified active $296,833,574 6 held

Fund Ownership of TSHA by Fund Type

Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026

Index funds and index ETFs hold 12.77% of shares outstanding.

Fund type Of shares outstanding Shares
Index funds 2.43% 7,912,990
Index ETFs 10.34% 33,704,871
Active ETFs 0.44% 1,438,708
Active funds 4.18% 13,608,618
Unclassified 0.00% 4,999
All registered funds 17.39% 56,670,186
How fund types are measured

Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.

Holder type: Registered adviser 107 Exempt adviser 3 Adviser 7 Bank 14 Insurer 3 Broker-dealer 1 Benefit plan 4 Non-US 9 Holding company 10 Unknown 53
Showing 100 of 216
All Common Calls Puts
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Holder Value (USD) % of 13F Shares Open
Avoro Capital Advisors LLC $162,683,327 7.96% 23,888,888
RA CAPITAL MANAGEMENT, L.P. $160,413,962 7.85% 23,555,648
GOLDMAN SACHS GROUP INC $154,676,332 7.57% 22,713,118
BlackRock, Inc. $140,912,017 6.90% 20,691,927
Vestal Point Capital, LP $132,216,150 6.47% 19,415,000
MORGAN STANLEY $112,279,729 5.49% 16,487,479
RTW INVESTMENTS, LP $92,345,356 4.52% 13,560,258
FMR LLC $90,820,972 4.44% 13,336,413
VANGUARD CAPITAL MANAGEMENT LLC $84,979,231 4.16% 12,478,595
STATE STREET CORP $77,783,275 3.81% 11,421,920
Siren, L.L.C. $67,055,202 3.28% 9,846,579
Octagon Capital Advisors LP $66,010,991 3.23% 9,693,244
GEODE CAPITAL MANAGEMENT, LLC $44,676,282 2.19% 6,560,394
Polar Capital Holdings Plc $34,847,675 1.71% 5,117,133
MPM BIOIMPACT LLC $30,645,000 1.50% 4,500,000
D. E. Shaw & Co., Inc. $29,954,819 1.47% 4,398,652
BAKER BROS. ADVISORS LP $27,272,388 1.33% 4,004,756
WELLINGTON MANAGEMENT GROUP LLP $27,073,867 1.32% 3,975,605
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND $26,460,261 1.29% 3,885,501
Casdin Capital, LLC $22,132,500 1.08% 3,250,000
VANGUARD PORTFOLIO MANAGEMENT LLC $21,383,461 1.05% 3,140,009
ADAR1 Capital Management, LLC $20,705,573 1.01% 3,040,466
Pictet Asset Management Holding SA $18,868,473 0.92% 2,770,701
Aberdeen Group plc $15,847,905 0.78% 2,327,152
FARALLON CAPITAL MANAGEMENT LLC $15,322,500 0.75% 2,250,000
NORGES BANK $15,210,816 0.74% 2,233,600
NORTHERN TRUST CORP $15,160,487 0.74% 2,226,210
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $14,986,732 0.73% 2,200,695
MILLENNIUM MANAGEMENT LLC $14,483,766 0.71% 2,126,838
ORBIMED ADVISORS LLC $13,620,000 0.67% 2,000,000
RICE HALL JAMES & ASSOCIATES, LLC $13,567,079 0.66% 1,992,229
VANGUARD FIDUCIARY TRUST CO $12,914,987 0.63% 1,896,474
B Group, Inc. $12,261,786 0.60% 1,800,556
Affinity Asset Advisors, LLC $11,917,500 0.58% 1,750,000
BARCLAYS PLC $11,104,787 0.54% 1,630,659
CITADEL ADVISORS LLC $10,455,303 0.51% 1,535,287
Seven Fleet Capital Management LP $10,244,964 0.50% 1,504,400
HEIGHTS CAPITAL MANAGEMENT, INC $10,215,000 0.50% 1,500,000
Palo Alto Investors LP $9,475,311 0.46% 1,391,382
BANK OF AMERICA CORP /DE/ $9,349,073 0.46% 1,372,845
Granahan Investment Management, LLC $8,888,255 0.43% 1,305,177
FIRST TRUST ADVISORS LP $5,387,860 0.26% 791,169
JPMORGAN CHASE & CO $5,218,378 0.26% 766,282
Sands Capital Alternatives, LLC $4,936,385 0.24% 724,873
GordonMD Global Investments LP $4,924,889 0.24% 723,185
Bank of New York Mellon Corp $4,753,180 0.23% 697,971
BNP PARIBAS ARBITRAGE, SA $4,358,638 0.21% 640,035
Quantum Private Wealth, LLC $4,071,665 0.20% 836,071
PANAGORA ASSET MANAGEMENT INC $4,020,535 0.20% 590,387
UBS Group AG $4,007,186 0.20% 588,427
AFFINITY WEALTH MANAGEMENT LLC $3,928,062 0.19% 576,808
Squarepoint Ops LLC $3,876,721 0.19% 569,269
ACUTA CAPITAL PARTNERS, LLC $3,825,912 0.19% 561,808
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,799,980 0.19% 558,000
Nuveen, LLC $3,784,268 0.19% 555,693
ADAGE CAPITAL PARTNERS GP, L.L.C. $3,765,930 0.18% 553,000
DIADEMA PARTNERS LP $3,559,035 0.17% 522,619
Woodline Partners LP $3,499,168 0.17% 513,828
Holocene Advisors, LP $3,473,100 0.17% 510,000
Ghisallo Capital Management LLC $3,439,050 0.17% 505,000
Burkehill Global Management, LP $3,405,000 0.17% 500,000
POLEN CAPITAL MANAGEMENT LLC $3,331,581 0.16% 489,219
DIMENSIONAL FUND ADVISORS LP $3,165,088 0.15% 464,771
VOYA INVESTMENT MANAGEMENT LLC $2,896,720 0.14% 425,363
Hennion & Walsh Asset Management, Inc. $2,613,918 0.13% 536,739
Trexquant Investment LP $2,584,919 0.13% 379,577
Swiss National Bank $2,512,890 0.12% 369,000
MOORE CAPITAL MANAGEMENT, LP $2,440,526 0.12% 358,374
WELLS FARGO & COMPANY/MN $2,269,866 0.11% 333,314
Jefferies Financial Group Inc. $2,239,128 0.11% 328,800
CITIGROUP INC $2,090,035 0.10% 306,907
RHUMBLINE ADVISERS $2,042,829 0.10% 299,975
ALPS ADVISORS INC $1,978,597 0.10% 290,543
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $1,856,404 0.09% 272,600
Invesco Ltd. $1,800,420 0.09% 264,379
Ensign Peak Advisors, Inc $1,790,321 0.09% 262,896
Qube Research & Technologies Ltd $1,767,910 0.09% 259,605
SPHERA FUNDS MANAGEMENT LTD. $1,702,500 0.08% 250,000
ALLIANCEBERNSTEIN L.P. $1,686,700 0.08% 247,680
DEUTSCHE BANK AG\ $1,657,410 0.08% 243,379
TWO SIGMA INVESTMENTS, LP $1,598,415 0.08% 234,716
JANE STREET GROUP, LLC $1,555,096 0.08% 228,355
Chicago Partners Investment Group LLC $1,514,183 0.07% 222,347
SG Americas Securities, LLC $1,377,390 0.07% 202,260
Monashee Investment Management LLC $1,362,000 0.07% 200,000
PRICE T ROWE ASSOCIATES INC /MD/ $1,358,554 0.07% 199,494
Privium Fund Management B.V. $1,354,509 0.07% 198,900
VICTORY CAPITAL MANAGEMENT INC $1,345,506 0.07% 197,578
Balyasny Asset Management L.P. $1,289,350 0.06% 189,332
STATE OF WISCONSIN INVESTMENT BOARD $1,205,976 0.06% 177,089
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $1,153,436 0.06% 169,374
RAYMOND JAMES FINANCIAL INC $1,130,745 0.06% 166,042
WEXFORD CAPITAL LP $1,094,053 0.05% 160,654
Rafferty Asset Management, LLC $1,053,547 0.05% 154,706
Palumbo Wealth Management LLC $1,015,868 0.05% 149,173
MetLife Investment Management, LLC $959,161 0.05% 140,846
Vanguard Global Advisers, LLC $911,321 0.04% 133,821
Persistent Asset Partners Ltd $908,528 0.04% 133,411
VANGUARD ASSET MANAGEMENT, Ltd $903,101 0.04% 132,614
AQR CAPITAL MANAGEMENT LLC $876,881 0.04% 128,764

Showing the top 100 of 216 holders. Create a free account to see every holder, past quarters, search, filters and CSV export.

Key facts CIK 1806310 CUSIP 877619106 13F (30d) 19 filings 19 filers Visit website Investor relations