CHARLES SCHWAB INVESTMENT MANAGEMENT INC

Position in TSHA — Taysha Gene Therapies, Inc.

CIK 884546 SAN FRANCISCO, CA

Position in TSHA

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$8,084,437

-$2,381,942 QoQ

Shares Held

1,808,599

-5.0% QoQ

Ownership

0.629%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Dec 2020

22 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

CHARLES SCHWAB INVESTMENT MANAGEMENT INC holds $6,182,986,350 across 288 Biotechnology names. TSHA ranks #104 (0.1% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	1,920,871	$857,745,736
2	REGN	Regeneron Pharmaceuticals, Inc.	804,508	$621,595,061
3	MRNA	Moderna, Inc.	4,734,356	$240,505,284
4	ALNY	Alnylam Pharmaceuticals, Inc.	673,356	$222,793,299
5	INSM	INSMED Inc	1,069,390	$174,866,652
6	RVMD	Revolution Medicines, Inc.	1,735,476	$168,775,041
7	INCY	Incyte Corp	1,729,102	$162,743,080
8	BBIO	BridgeBio Pharma, Inc.	1,976,094	$146,744,740

22 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$8,084,437	1,808,599	-5.0%	Shares	Sole	2026-05-15
2025-12-31	$10,466,379	1,902,978	+3.1%	Shares	Sole	2026-02-13
2025-09-30	$6,038,087	1,846,510	+275.5%	Shares	Sole	2025-11-10
2025-06-30	$1,135,847	491,709	-10.1%	Shares	Sole	2025-08-12
2025-03-31	$760,507	547,128	+15.4%	Shares	Sole	2025-09-15
2024-12-31	$820,464	474,257	+2.5%	Shares	Sole	2025-02-06
2024-09-30	$930,362	462,867	+7.7%	Shares	Sole	2024-11-12
2024-06-30	$962,626	429,744	+735.1%	Shares	Sole	2024-08-12
2024-03-31	$147,695	51,462	+218.8%	Shares	Sole	2024-05-09
2023-12-31	$28,567	16,140	0.0%	Shares	Sole	2024-02-06
2023-09-30	$51,002	16,140	0.0%	Shares	Sole	2023-11-08
2023-06-30	$10,668	16,140	0.0%	Shares	Sole	2023-08-10
2023-03-31	$12,879	16,140	0.0%	Shares	Sole	2023-05-12
2022-12-31	$36,476	16,140	0.0%	Shares	Sole	2023-02-13
2022-09-30	$31,150	16,140	-82.2%	Shares	Sole	2022-11-14
2022-06-30	$337,444	90,711	-45.1%	Shares	Sole	2022-08-15
2022-03-31	$1,078,049	165,345	+1.7%	Shares	Sole	2022-05-13
2021-12-31	$1,893,824	162,560	+2.6%	Shares	Sole	2022-02-11
2021-09-30	$2,949,538	158,407	+82.0%	Shares	Sole	2021-11-16
2021-06-30	$1,845,036	87,030	+49.4%	Shares	Sole	2021-08-16
2021-03-31	$1,182,332	58,243	+11.5%	Shares	Sole	2021-05-17
2020-12-31	$1,386,237	52,232	—	Shares	Sole	2021-02-16
No filing history on record for this holder in this stock.