RTW INVESTMENTS, LP

Position in TSHA — Taysha Gene Therapies, Inc.

CIK 1493215 NEW YORK, NY

Position in TSHA

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$92,345,356

+$31,194,648 QoQ

Shares Held

13,560,258

-0.9% QoQ

Ownership

4.16%

of shares outstanding

% of Portfolio

0.79%

of 13F equity value

Holder Rank

of 208 holders

Holding Since

Sep 2023

12 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

RTW INVESTMENTS, LP holds $9,530,420,260 across 63 Biotechnology names. TSHA ranks #27 (1.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	MDGL	Madrigal Pharmaceuticals, Inc.	1,993,687	$1,070,510,234
2	ARGX	Argenx SE	709,446	$658,202,715
3	PTCT	Ptc Therapeutics, Inc.	7,746,415	$631,875,071
4	PTGX	Protagonist Therapeutics, Inc	5,061,175	$620,398,831
5	CGON	CG Oncology, Inc.	8,514,590	$604,961,619
6	INSM	INSMED Inc	4,842,880	$516,347,865
7	TNGX	Tango Therapeutics, Inc.	13,900,620	$434,533,381
8	SYRE	Spyre Therapeutics, Inc.	4,251,996	$377,492,204

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$92,345,356	13,560,258	-0.9%	Shares	Sole	2026-08-14
2026-03-31	$61,150,708	13,680,248	-16.6%	Shares	Sole	2026-05-15
2025-12-31	$90,190,633	16,398,297	-32.7%	Shares	Sole	2026-02-17
2025-09-30	$79,638,531	24,354,291	-2.7%	Shares	Sole	2025-11-14
2025-06-30	$57,799,859	25,021,584	+33.2%	Shares	Sole	2025-08-14
2025-03-31	$26,115,133	18,787,866	+116.6%	Shares	Sole	2025-05-15
2024-12-31	$15,003,649	8,672,630	-42.0%	Shares	Sole	2025-02-14
2024-09-30	$30,042,304	14,946,420	-20.5%	Shares	Sole	2024-11-14
2024-06-30	$42,112,669	18,800,299	+1.1%	Shares	Sole	2024-08-14
2024-03-31	$53,362,440	18,593,185	+10.1%	Shares	Sole	2024-05-15
2023-12-31	$29,900,937	16,893,185	0.0%	Shares	Sole	2024-02-14
2023-09-30	$53,382,464	16,893,185	—	Shares	Sole	2023-11-14
No filing history on record for this holder in this stock.