Palo Alto Investors LP

Position in TSHA — Taysha Gene Therapies, Inc.

CIK 1306923 PALO ALTO, CA

Position in TSHA

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$6,219,477

-$288,095 QoQ

Shares Held

1,391,382

+17.6% QoQ

Ownership

0.484%

of shares outstanding

% of Portfolio

0.97%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Dec 2023

10 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

Palo Alto Investors LP holds $530,756,561 across 38 Biotechnology names. TSHA ranks #21 (1.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	INSM	INSMED Inc	415,269	$67,904,786
2	ACAD	Acadia Pharmaceuticals Inc	2,872,695	$63,946,190
3	PTCT	Ptc Therapeutics, Inc.	921,607	$62,789,084
4	BMRN	Biomarin Pharmaceutical Inc	685,182	$38,705,931
5	MIRM	Mirum Pharmaceuticals, Inc.	325,175	$30,039,666
6	DYN	Dyne Therapeutics, Inc.	1,652,972	$29,968,382
7	IRON	Disc Medicine, Inc.	401,719	$25,685,912
8	ANAB	Anaptysbio, Inc	638,161	$23,594,918

10 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$6,219,477	1,391,382	+17.6%	Shares	Sole	2026-05-15
2025-12-31	$6,507,572	1,183,195	-5.0%	Shares	Sole	2026-02-17
2025-09-30	$4,074,527	1,246,033	0.0%	Shares	Sole	2025-11-14
2025-06-30	$2,878,336	1,246,033	-12.2%	Shares	Sole	2025-08-14
2025-03-31	$1,973,060	1,419,468	+75.0%	Shares	Sole	2025-05-15
2024-12-31	$1,403,493	811,268	0.0%	Shares	Sole	2025-02-14
2024-09-30	$1,630,648	811,268	0.0%	Shares	Sole	2024-11-14
2024-06-30	$1,817,240	811,268	0.0%	Shares	Sole	2024-08-14
2024-03-31	$2,328,339	811,268	+53.1%	Shares	Sole	2024-05-15
2023-12-31	$937,853	529,861	—	Shares	Sole	2024-02-15
No filing history on record for this holder in this stock.