TCG Crossover Management, LLC
Filing Date
Global Rank
#848
/ 8,700
▲ 191
Top Industry
Biotechnology
93.5%
Period ended 2 months ago
Filed Aug 14, 2026 · 30d
19 quarters · since Dec 2021
Portfolio Concentration
54 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026Top Position
19.2%
−2.4 pts
Top 5
41.0%
−4.7 pts
Top 10
57.4%
−4.4 pts
HHI
618
Diversified−116
Portfolio Trend
19 quarters · across all stocks
Sector Breakdown
As of Jun 30, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 99.8% | $4,153,007,248 |
| Financial Services | 0.2% | $7,622,000 |
Last Quarter's Activity
Export CSVTrimmed
Positions the filer reduced
9 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| ALXO | Alx Oncology Holdings Inc | −7,356,362 | 5,655,487 | $11,706,858 | |
| BHVN | Biohaven Ltd. | −2,851,365 | 1,779,952 | $26,485,685 | |
| ARVN | Arvinas, Inc. | −1,680,363 | 707,098 | $5,875,984 | |
| TNGX | Tango Therapeutics, Inc. | −1,449,870 | 9,081,201 | $283,878,343 | |
| TRDA | Entrada Therapeutics, Inc. | −1,227,270 | 1,060,230 | $7,803,292 | |
| ABVX | Abivax S.A. | −473,251 | 6,007,834 | $800,603,958 | |
| LBRX | Lb Pharmaceuticals Inc | −392,179 | 1,447,310 | $46,972,446 | |
| RVMD | Revolution Medicines, Inc. | −235,574 | 340,899 | $63,843,564 | |
| COGT | Cogent Biosciences, Inc. | −92,458 | 4,854,436 | $187,866,673 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
12 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| ZLAB | Zai Lab Ltd | 6,137,627 | $116,614,913 | |
| AURA | Aura Biosciences, Inc. | 9,533,333 | $67,686,664 | |
| TRAX | First Tracks Biotherapeutics, Inc. | 2,895,304 | $58,253,516 | |
| EDIT | Editas Medicine, Inc. | 11,111,111 | $35,999,999 | |
| PHVS | Pharvaris N.V. | 1,008,229 | $34,864,558 | |
| IFRX | InflaRx N.V. | 14,500,000 | $32,480,000 | |
| ALT | Altimmune, Inc. | 10,000,000 | $30,400,000 | |
| AKTS | Aktis Oncology, Inc. | 696,560 | $22,450,128 | |
| — | 920,000 | $19,550,000 | ||
| RACC | Research Alliance Corp III | 500,000 | $5,350,000 | |
| JATT | JATT II Acquisition Corp. | 200,000 | $2,272,000 | |
| EIKN | Eikon Therapeutics, Inc. | 37,902 | $494,621 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
7 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| FULC | Fulcrum Therapeutics, Inc. | 5,250,000 | $40,267,500 | |
| LQDA | Liquidia Corp | 403,048 | $15,211,031 | |
| URGN | UroGen Pharma Ltd. | 405,365 | $7,288,462 | |
| GPCR | Structure Therapeutics Inc. | 140,411 | $6,767,810 | |
| UPB | Upstream Bio, Inc. | 181,063 | $1,629,567 | |
| VTGN | Vistagen Therapeutics, Inc. | 2,676,580 | $1,525,650 | |
| CNTA | Centessa Pharmaceuticals plc | 4,286,480 | $0 | |
| No positions match the current search. | ||||
54 tracked positions ·
$4,160,629,248 total
· filing declares
54 positions · $4,160,526,316
· as of Jun 30, 2026
Showing 1–50
of 54 positions by value
· page 1 of 2
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| ABVX |
Abivax S.A.
Healthcare
|
Reduced | 6,007,834 | $800,603,958 | 19.24% | |
| TNGX |
Tango Therapeutics, Inc.
Healthcare
|
Reduced | 9,081,201 | $283,878,343 | 6.82% | |
| CGON |
CG Oncology, Inc.
Healthcare
|
Held | 3,670,206 | $260,768,136 | 6.27% | |
| COGT |
Cogent Biosciences, Inc.
Healthcare
|
Reduced | 4,854,436 | $187,866,673 | 4.52% | |
| IMVT |
Immunovant, Inc.
Healthcare
|
Held | 4,457,988 | $171,766,277 | 4.13% | |
| SYRE |
Spyre Therapeutics, Inc.
Healthcare
|
Held | 1,900,582 | $168,733,669 | 4.06% | |
| DNTH |
Dianthus Therapeutics, Inc. /DE/
Healthcare
|
Held | 1,676,624 | $163,437,307 | 3.93% | |
| MIRM |
Mirum Pharmaceuticals, Inc.
Healthcare
|
Held | 1,062,049 | $124,334,076 | 2.99% | |
| ZLAB |
Zai Lab Ltd
Healthcare
|
NEW | 6,137,627 | $116,614,913 | 2.80% | |
| AMLX |
Amylyx Pharmaceuticals, Inc.
Healthcare
|
Held | 6,243,812 | $112,138,863 | 2.70% | |
| GLUE |
Monte Rosa Therapeutics, Inc.
Healthcare
|
Held | 4,622,151 | $111,856,054 | 2.69% | |
| BCRX |
Biocryst Pharmaceuticals Inc
Healthcare
|
Held | 11,020,968 | $110,209,680 | 2.65% | |
| VOR |
Vor Biopharma Inc.
Healthcare
|
Held | 5,673,078 | $104,441,365 | 2.51% | |
| TYRA |
Tyra Biosciences, Inc.
Healthcare
|
Held | 3,248,980 | $103,772,421 | 2.49% | |
| DYN |
Dyne Therapeutics, Inc.
Healthcare
|
Held | 4,615,144 | $102,502,348 | 2.46% | |
| IRON |
Disc Medicine, Inc.
Healthcare
|
Held | 1,341,862 | $98,143,786 | 2.36% | |
| RLAY |
Relay Therapeutics, Inc.
Healthcare
|
Held | 4,273,356 | $79,954,490 | 1.92% | |
| SVRA |
Savara Inc
Healthcare
|
Held | 12,362,205 | $76,151,182 | 1.83% | |
| AURA |
Aura Biosciences, Inc.
Healthcare
|
NEW | 9,533,333 | $67,686,664 | 1.63% | |
| RVMD |
Revolution Medicines, Inc.
Healthcare
|
Reduced | 340,899 | $63,843,564 | 1.53% | |
| TRAX |
First Tracks Biotherapeutics, Inc.
Healthcare
|
NEW | 2,895,304 | $58,253,516 | 1.40% | |
| KOD |
Kodiak Sciences Inc.
Healthcare
|
Held | 1,445,538 | $56,318,160 | 1.35% | |
| AVTX |
Avalo Therapeutics, Inc.
Healthcare
|
Added | 3,017,120 | $55,756,377 | 1.34% | |
| LBRX |
Lb Pharmaceuticals Inc
Healthcare
|
Reduced | 1,447,310 | $46,972,446 | 1.13% | |
| IPSC |
Century Therapeutics, Inc.
Healthcare
|
Held | 17,754,430 | $43,498,353 | 1.05% | |
| TECX |
Tectonic Therapeutic, Inc.
Healthcare
|
Held | 1,204,891 | $41,424,152 | 1.00% | |
| XNCR |
Xencor Inc
Healthcare
|
Held | 2,452,138 | $39,479,421 | 0.95% | |
| SRZN |
Surrozen, Inc./DE
Healthcare
|
Held | 1,473,101 | $38,226,970 | 0.92% | |
| EDIT |
Editas Medicine, Inc.
Healthcare
|
NEW | 11,111,111 | $35,999,999 | 0.87% | |
| MBX |
MBX Biosciences, Inc.
Healthcare
|
Held | 650,000 | $35,880,000 | 0.86% | |
| PHVS |
Pharvaris N.V.
Healthcare
|
NEW | 1,008,229 | $34,864,558 | 0.84% | |
| SLN |
Silence Therapeutics plc
Healthcare
|
Held | 3,033,560 | $33,308,488 | 0.80% | |
| IFRX |
InflaRx N.V.
Healthcare
|
NEW | 14,500,000 | $32,480,000 | 0.78% | |
| ALT |
Altimmune, Inc.
Healthcare
|
NEW | 10,000,000 | $30,400,000 | 0.73% | |
| JANX |
Janux Therapeutics, Inc.
Healthcare
|
Held | 1,789,617 | $27,488,517 | 0.66% | |
| CATX |
Perspective Therapeutics, Inc.
Healthcare
|
Held | 7,915,567 | $26,992,083 | 0.65% | |
| AGMB |
Agomab Therapeutics NV
Healthcare
|
Held | 2,053,233 | $26,650,964 | 0.64% | |
| BHVN |
Biohaven Ltd.
Healthcare
|
Reduced | 1,779,952 | $26,485,685 | 0.64% | |
| AKTS |
Aktis Oncology, Inc.
Healthcare
|
NEW | 696,560 | $22,450,128 | 0.54% | |
| ALEC |
Alector, Inc.
Healthcare
|
Held | 10,000,000 | $20,100,000 | 0.48% | |
|
|
NEW | 920,000 | $19,550,000 | 0.47% | ||
| MNPR |
Monopar Therapeutics
Healthcare
|
Added | 203,327 | $18,826,046 | 0.45% | |
| OCUL |
Ocular Therapeutix, Inc
Healthcare
|
Held | 1,647,752 | $16,180,924 | 0.39% | |
| ADCT |
ADC Therapeutics SA
Healthcare
|
Held | 11,390,175 | $12,187,487 | 0.29% | |
| ALXO |
Alx Oncology Holdings Inc
Healthcare
|
Reduced | 5,655,487 | $11,706,858 | 0.28% | |
| TRDA |
Entrada Therapeutics, Inc.
Healthcare
|
Reduced | 1,060,230 | $7,803,292 | 0.19% | |
| CGEM |
Cullinan Therapeutics, Inc.
Healthcare
|
Held | 406,786 | $7,407,573 | 0.18% | |
| ARVN |
Arvinas, Inc.
Healthcare
|
Reduced | 707,098 | $5,875,984 | 0.14% | |
| KRRO |
Korro Bio, Inc.
Healthcare
|
Held | 416,301 | $5,486,847 | 0.13% | |
| RACC |
Research Alliance Corp III
Financial Services
|
NEW | 500,000 | $5,350,000 | 0.13% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.