ALXO · Alx Oncology Holdings Inc

$2.00 -0.05 (-2.44%) At close · Aug 28

Russell 2000 member Rebalance outlook locked

Market Cap

$276.55M

138.28M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 95

Total Value: $217,865,468

Total Shares: 105,249,046

Institutional Ownership Trend

24 quarters

Holder Concentration

Across 95 13F filers · Δ vs Mar 31, 2026

Top Holder

12.4%

−1.4 pts

Top 5

44.9%

−10.9 pts

Top 10

69.2%

−7.9 pts

HHI

619

Broadly held−194

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +25

Institutional value: +15.2%

Shares held: +11.6%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega BlackRock, Inc.	+6,951,731	7,399,530
Mega GEODE CAPITAL MANAGEMENT, LLC	+2,294,372	2,787,809
Mega STATE STREET CORP	+1,323,077	1,498,905
Mega JPMORGAN CHASE & CO	+1,044,629	1,044,728
Mega NORTHERN TRUST CORP	+798,705	935,669

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mid TCG Crossover Management, LLC	−7,356,362	5,655,487
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP	−1,214,750	147,957
Large MARSHALL WACE, LLP	−685,720	3,071,496
Mid Redmile Group, LLC	−571,684	7,392,504
Mega BANK OF AMERICA CORP /DE/	−501,751	76,032

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Small SILVERARC CAPITAL MANAGEMENT, LLC	5,744,757	$11,891,646
Mid Nantahala Capital Management, LLC	750,000	$1,552,500
Mid ADAR1 Capital Management, LLC	533,660	$1,104,676
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC	241,113	$499,103
Mega Bank of New York Mellon Corp	238,447	$493,585

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Large ADAGE CAPITAL PARTNERS GP, L.L.C.	2,000,000	$4,010,000
Small Squadron Capital Management LLC	1,460,000	$2,927,300
Mega Qube Research & Technologies Ltd	107,647	$215,832
Large BANK OF NOVA SCOTIA	105,858	$212,245
Mega JANE STREET GROUP, LLC	95,101	$190,677

Filter: New 37 Increased 29 Reduced 11 Sold out 12 Unchanged 18

Showing 96 of 96

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

RA CAPITAL MANAGEMENT, L.P.

$26,934,527

12.36%

13,011,849

venBio Partners LLC

$26,671,200

12.24%

12,884,638

BlackRock, Inc.

$15,317,024

7.03%

7,399,530

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	70,811	$146,578	1.0%	Sole
BlackRock Investment Management, LLC	319,462	$661,286	4.3%	Sole
BLACKROCK ADVISORS LLC	238,987	$494,703	3.2%	Sole
BlackRock Fund Advisors	3,989,067	$8,257,368	53.9%	Sole
BlackRock Institutional Trust Company, N.A.	2,780,908	$5,756,479	37.6%	Sole
Aperio Group, LLC	295	$610	0.0%	Sole

Redmile Group, LLC

$15,302,483

7.02%

7,392,504

Blackstone Inc.

$13,648,634

6.26%

6,593,543

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Blackstone Alternative Asset Management L.P.	6,593,543	$13,648,634	100.0%	Other

Driehaus Capital Management LLC

$12,472,246

5.72%

6,025,240

SILVERARC CAPITAL MANAGEMENT, LLC

$11,891,646

5.46%

5,744,757

TCG Crossover Management, LLC

$11,706,858

5.37%

5,655,487

VANGUARD CAPITAL MANAGEMENT LLC

$10,295,012

4.73%

4,973,436

Vivo Capital, LLC

$6,592,355

3.03%

3,184,713

MARSHALL WACE, LLP

$6,357,995

2.92%

3,071,496

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	3,071,496	$6,357,995	100.0%	Other

5AM Venture Management, LLC

$6,328,662

2.90%

3,057,325

Almitas Capital LLC

$6,082,552

2.79%

2,938,431

ORBIMED ADVISORS LLC

$5,933,149

2.72%

2,866,256

GEODE CAPITAL MANAGEMENT, LLC

$5,770,764

2.65%

2,787,809

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	420,432	$870,294	15.1%	Defined
Held directly	2,367,377	$4,900,470	84.9%	Defined

TWO SIGMA INVESTMENTS, LP

$4,508,824

2.07%

2,178,176

MILLENNIUM MANAGEMENT LLC

$3,195,239

1.47%

1,543,594

STATE STREET CORP

$3,102,733

1.42%

1,498,905

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SSGA FUNDS MANAGEMENT, INC. joint	1,498,905	$3,102,733	100.0%	Defined

ACADIAN ASSET MANAGEMENT LLC

$2,718,924

1.25%

1,313,490

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Acadian Inc	1,313,490	$2,718,924	100.0%	Defined

JPMORGAN CHASE & CO

$2,162,585

0.99%

1,044,728

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	124,253	$257,203	11.9%	Defined
J.P. Morgan Investment Management Inc.	920,376	$1,905,178	88.1%	Defined
J.P. Morgan Securities plc	99	$204	0.0%	Defined

NORTHERN TRUST CORP

$1,936,834

0.89%

935,669

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	918,789	$1,901,893	98.2%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	16,880	$34,941	1.8%	Other

Ensign Peak Advisors, Inc

$1,677,314

0.77%

810,297

Nantahala Capital Management, LLC

$1,552,500

0.71%

750,000

VANGUARD PORTFOLIO MANAGEMENT LLC

$1,550,904

0.71%

749,229

VANGUARD FIDUCIARY TRUST CO

$1,539,026

0.71%

743,491

GOLDMAN SACHS GROUP INC

$1,536,625

0.71%

742,331

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	311,129	$644,037	41.9%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	431,202	$892,588	58.1%	Defined

RENAISSANCE TECHNOLOGIES LLC

$1,249,859

0.57%

603,797

ADAR1 Capital Management, LLC

$1,104,676

0.51%

533,660

UBS Group AG

$958,291

0.44%

462,943

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	432,049	$894,341	93.3%	Defined
UBS Switzerland AG	30,894	$63,950	6.7%	Defined

GSA CAPITAL PARTNERS LLP

$856,038

0.39%

413,545

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$499,103

0.23%

241,113

Bank of New York Mellon Corp

$493,585

0.23%

238,447

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	62,404	$129,176	26.2%	Defined
The Bank of New York Mellon	176,043	$364,409	73.8%	Defined

BRIDGEWAY CAPITAL MANAGEMENT, LLC

$467,969

0.21%

226,072

Atom Investors LP

$454,120

0.21%

219,382

IEQ CAPITAL, LLC

$363,040

0.17%

175,382

MORGAN STANLEY

$326,794

0.15%

157,873

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	117	$242	0.1%	Defined
MORGAN STANLEY & CO. LLC	29,285	$60,619	18.5%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	93,594	$193,739	59.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	32,493	$67,260	20.6%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	2,384	$4,934	1.5%	Defined

Invesco Ltd.

$310,338

0.14%

149,923

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	15,694	$32,485	10.5%	Defined
Invesco Trust Co joint	43,026	$89,063	28.7%	Defined
Invesco Capital Management LLC	91,203	$188,790	60.8%	Defined

Nuveen, LLC

$297,345

0.14%

143,645

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TEACHERS ADVISORS, LLC joint	143,645	$297,345	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$254,934

0.12%

123,157

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	123,157	$254,934	100.0%	Other

RHUMBLINE ADVISERS

$223,357

0.10%

107,902

DEUTSCHE BANK AG\

$222,375

0.10%

107,428

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	2,089	$4,324	1.9%	Defined
DWS Investments UK Ltd	105,339	$218,051	98.1%	Defined

WELLS FARGO & COMPANY/MN

$206,846

0.09%

99,926

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	98,426	$203,741	98.5%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	1,500	$3,105	1.5%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$185,842

0.09%

89,779

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	89,779	$185,842	100.0%	Defined

Verdad Advisers, LP

$170,154

0.08%

82,200

BANK OF AMERICA CORP /DE/

$157,386

0.07%

76,032

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	76,032	$157,386	100.0%	Defined

Graham Capital Management, L.P.

$154,879

0.07%

74,821

XTX Topco Ltd

$144,189

0.07%

69,657

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	69,657	$144,189	100.0%	Defined

MetLife Investment Management, LLC

$134,465

0.06%

64,959

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	64,959	$134,465	100.0%	Defined

CITIGROUP INC

$104,813

0.05%

50,635

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	50,635	$104,813	100.0%	Defined

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$102,841

0.05%

49,682

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	49,682	$102,841	100.0%	Defined

Squarepoint Ops LLC

$97,018

0.04%

46,869

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	46,869	$97,018	100.0%	Defined

Vanguard Global Advisers, LLC

$89,088

0.04%

43,038

AXQ CAPITAL, LP

$83,944

0.04%

40,553

WEALTH ENHANCEMENT ADVISORY SERVICES, LLC

$78,682

0.04%

38,011

CITADEL ADVISORS LLC

$74,934

0.03%

36,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	36,200	$74,934	100.0%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$68,517

0.03%

33,100

BARCLAYS PLC

$68,069

0.03%

32,884

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	25,586	$52,963	77.8%	Defined
BARCLAYS CAPITAL INC.	7,298	$15,106	22.2%	Defined

Police & Firemen's Retirement System of New Jersey

$65,871

0.03%

31,822

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	31,822	$65,871	100.0%	Defined

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$64,163

0.03%

30,997

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	30,997	$64,163	100.0%	Defined

ALLIANCEBERNSTEIN L.P.

$54,523

0.03%

26,340

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	26,340	$54,523	100.0%	Defined

JACOBS LEVY EQUITY MANAGEMENT, INC

$52,799

0.02%

25,507

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$51,336

0.02%

24,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	24,800	$51,336	100.0%	Other

HC Advisors, LLC

$47,403

0.02%

22,900

Callan Family Office, LLC

$46,407

0.02%

22,419

VOYA INVESTMENT MANAGEMENT LLC

$44,424

0.02%

21,461

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	21,461	$44,424	100.0%	Defined

AMERICAN CENTURY COMPANIES INC

$44,368

0.02%

21,434

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	21,434	$44,368	100.0%	Defined

CAXTON CORP

$43,358

0.02%

20,946

INTECH INVESTMENT MANAGEMENT LLC

$40,207

0.02%

19,424

COMMONWEALTH EQUITY SERVICES, LLC

$38,193

0.02%

18,451

Bronte Capital Management Pty Ltd.

$37,456

0.02%

18,095

JSF Financial, LLC

$36,225

0.02%

17,500

BNP PARIBAS ARBITRAGE, SA

$34,395

0.02%

16,616

PRUDENTIAL FINANCIAL INC

$33,916

0.02%

16,385

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PGIM Quantitative Solutions LLC	16,385	$33,916	100.0%	Defined

MONETA GROUP INVESTMENT ADVISORS LLC

$31,455

0.01%

15,196

ProShare Advisors LLC

$29,238

0.01%

14,125

FMR LLC

$27,410

0.01%

13,242

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	13,132	$27,183	99.2%	Defined
STRATEGIC ADVISERS LLC	110	$227	0.8%	Defined

Lido Advisors, LLC

$27,365

0.01%

13,220

Abel Hall, LLC

$26,353

0.01%

12,731

Beacon Pointe Advisors, LLC

$25,875

0.01%

12,500

China Universal Asset Management Co., Ltd.

$25,875

0.01%

12,500

Legal & General Group Plc

$21,699

0.01%

10,483

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	10,483	$21,699	100.0%	Defined

Tower Research Capital LLC (TRC)

$21,521

0.01%

10,397

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	10,397	$21,521	100.0%	Defined

XPONANCE LLC

$21,070

0.01%

10,179

HSBC HOLDINGS PLC

$20,917

0.01%

10,105

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HSBC BANK PLC	10,105	$20,917	100.0%	Defined

Ameritas Investment Partners, Inc.

$20,269

0.01%

9,792

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	9,792	$20,269	100.0%	Other

Russell Investments Group, Ltd.

$17,859

0.01%

8,628

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	8,628	$17,859	100.0%	Defined

ROYAL BANK OF CANADA

$12,742

0.01%

6,156

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	3,494	$7,232	56.8%	Defined
RBC Capital Markets, LLC	2,662	$5,510	43.2%	Defined

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$3,076

0.00%

1,486

NISA INVESTMENT ADVISORS, LLC

$2,289

0.00%

1,106

Bradley & Co. Private Wealth Management, LLC

$2,070

0.00%

1,000

EverSource Wealth Advisors, LLC

$1,873

0.00%

905

Sterling Capital Management LLC

$784

0.00%

379

Integrated Wealth Concepts LLC

$269

0.00%

130

PNC FINANCIAL SERVICES GROUP, INC.

$207

0.00%

100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	100	$207	100.0%	Defined

Caitong International Asset Management Co., Ltd

$74

0.00%

SBI Securities Co., Ltd.

$28

0.00%

Key facts CIK 1810182 CUSIP 00166B105 13F (30d) 87 filings 87 filers Visit website Investor relations