RLAY · Relay Therapeutics, Inc. · Holdings

$18.74 -0.65 (-3.35%) At close · Oct 6

Russell 2000 member Rebalance outlook locked

Market Cap

$3.83B

219.14M

Volume · Oct 6 3.88M Avg daily vol (3M) 2.85M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 263

Total Value: $4,675,036,700

Total Shares: 249,955,978

Showing 1–100 of 270 holdings by value · page 1 of 3

Institutional Ownership Trend

25 quarters

Superinvestors Holding RLAY

All superinvestors →

Stanley Druckenmiller $6,529,790

Holder Concentration

Across 262 13F filers

Top Holder

11.2%

of institutional value

Top 5

37.4%

of institutional value

Top 10

55.7%

of institutional value

HHI

412

Broadly held

Showing 100 of 270

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

SB INVESTMENT ADVISERS (UK) LTD

$522,101,857

11.17%

27,904,963

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SB INVESTMENT ADVISERS (US) INC.	27,904,963	$522,101,857	100.0%	Sole

FMR LLC

$376,260,212

8.05%

20,110,113

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC joint	16,335,051	$305,628,803	81.2%	Defined
STRATEGIC ADVISERS LLC	3,109	$58,169	0.0%	Defined
Fidelity Institutional Asset Management Trust Co	1,490,162	$27,880,931	7.4%	Defined
FIAM LLC	2,281,791	$42,692,309	11.3%	Defined

Casdin Capital, LLC

$300,019,340

6.42%

16,035,240

BlackRock, Inc.

$286,042,253

6.12%

15,288,202

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	201,755	$3,774,836	1.3%	Sole
BlackRock Investment Management (Australia) Ltd	336	$6,286	0.0%	Sole
BlackRock Asset Management Canada Ltd	37,998	$710,942	0.2%	Sole
BlackRock Investment Management, LLC	471,076	$8,813,831	3.1%	Sole
BLACKROCK ADVISORS LLC	990,568	$18,533,527	6.5%	Sole
BlackRock Fund Advisors	7,433,534	$139,081,421	48.6%	Sole
BlackRock Institutional Trust Company, N.A.	4,896,384	$91,611,344	32.0%	Sole
BlackRock Fund Managers Ltd.	19,104	$357,435	0.1%	Sole
BlackRock Investment Management (UK) Ltd.	101,758	$1,903,892	0.7%	Sole
BlackRock Asset Management Ireland Ltd	714,866	$13,375,142	4.7%	Sole
BlackRock (Luxembourg) S.A.	6,027	$112,765	0.0%	Sole
BlackRock Asset Management Schweiz AG	22,140	$414,239	0.1%	Sole
Aperio Group, LLC	392,656	$7,346,593	2.6%	Sole

PERCEPTIVE ADVISORS LLC

$263,926,758

5.65%

14,106,187

Commodore Capital LP

$224,520,000

4.80%

12,000,000

STATE STREET CORP

$189,445,878

4.05%

10,125,381

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	10,125,381	$189,445,878	100.0%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$167,724,354

3.59%

8,964,423

PRICE T ROWE ASSOCIATES INC /MD/

$144,226,165

3.09%

7,708,507

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	270,226	$5,055,928	3.5%	Defined
Held directly	7,438,281	$139,170,237	96.5%	Sole

Nextech Invest, Ltd.

$126,788,427

2.71%

6,776,506

Bellevue Group AG

$115,739,498

2.48%

6,185,970

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BB Biotech AG joint	6,184,046	$115,703,500	100.0%	Defined
Bellevue Asset Management AG	1,924	$35,998	0.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$88,434,236

1.89%

4,726,576

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	615,580	$11,517,501	13.0%	Defined
Held directly	4,110,996	$76,916,735	87.0%	Defined

TCG Crossover Management, LLC

$79,954,490

1.71%

4,273,356

ALLIANCEBERNSTEIN L.P.

$76,628,676

1.64%

4,095,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	4,095,600	$76,628,676	100.0%	Defined

MORGAN STANLEY

$72,053,535

1.54%

3,851,071

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	6,144	$114,954	0.2%	Defined
MORGAN STANLEY & CO. LLC	352,125	$6,588,258	9.1%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	2,885,713	$53,991,690	74.9%	Defined
MORGAN STANLEY SMITH BARNEY LLC	6,085	$113,849	0.2%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	601,004	$11,244,784	15.6%	Defined

Siren, L.L.C.

$68,291,500

1.46%

3,650,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	3,650,000	$68,291,500	100.0%	Defined

GOLDMAN SACHS GROUP INC

$63,776,795

1.36%

3,408,701

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	2,777,017	$51,957,988	81.5%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	631,684	$11,818,807	18.5%	Defined

WESTFIELD CAPITAL MANAGEMENT CO LP

$62,556,810

1.34%

3,343,496

Kynam Capital Management, LP

$61,743,000

1.32%

3,300,000

DIMENSIONAL FUND ADVISORS LP

$58,516,720

1.25%

3,127,564

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	23,832	$445,896	0.8%	Defined
DFA Australia Ltd.	48,244	$902,645	1.5%	Defined
Dimensional Fund Advisors Pte. Ltd.	1,672	$31,283	0.1%	Defined
Dimensional Ireland Ltd	122,569	$2,293,265	3.9%	Defined
Held directly	2,931,247	$54,843,631	93.7%	Sole

Spruce Street Capital LP

$55,832,978

1.19%

2,984,125

VANGUARD PORTFOLIO MANAGEMENT LLC

$54,124,007

1.16%

2,892,785

BAKER BROS. ADVISORS LP

$52,889,109

1.13%

2,826,783

BANK OF AMERICA CORP /DE/

$50,425,468

1.08%

2,695,108

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	2,279,279	$42,645,310	84.6%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	44,342	$829,638	1.6%	Defined
BOFA SECURITIES, INC.	131,038	$2,451,720	4.9%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	240,449	$4,498,800	8.9%	Defined

MPM BIOIMPACT LLC

$45,197,223

0.97%

2,415,672

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

$41,890,361

0.90%

2,238,929

Pictet Asset Management Holding SA

$38,866,226

0.83%

2,077,297

NORTHERN TRUST CORP

$36,549,159

0.78%

1,953,456

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	1,847,483	$34,566,406	94.6%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	80,907	$1,513,769	4.1%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	25,066	$468,984	1.3%	Other

T. Rowe Price Investment Management, Inc.

$35,838,237

0.77%

1,915,459

FRANKLIN RESOURCES INC

$34,742,842

0.74%

1,856,913

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST INTERNATIONAL LLC	362	$6,773	0.0%	Defined
FRANKLIN ADVISERS INC	1,856,551	$34,736,069	100.0%	Defined

Polar Capital Holdings Plc

$33,473,237

0.72%

1,789,056

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Polar Capital LLP	1,789,056	$33,473,237	100.0%	Defined

ADAGE CAPITAL PARTNERS GP, L.L.C.

$32,555,400

0.70%

1,740,000

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$28,080,286

0.60%

1,500,817

Elmind Capital, LP

$27,415,370

0.59%

1,465,279

Alphabet Inc.

$26,381,642

0.56%

1,410,029

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GV Management Company, L.L.C.	1,410,029	$26,381,642	100.0%	Defined

PANAGORA ASSET MANAGEMENT INC

$24,158,015

0.52%

1,291,182

AQR CAPITAL MANAGEMENT LLC

$23,938,936

0.51%

1,279,473

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	92	$1,721	0.0%	Other
Prism Planning Partners LLC	116	$2,170	0.0%	Other
Compound Planning, Inc.	21	$392	0.0%	Other
Arax Advisory Partners	13,060	$244,352	1.0%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	12,212	$228,486	1.0%	Other
Stokes Family Office, LLC	8,904	$166,593	0.7%	Other
Held directly	1,245,068	$23,295,222	97.3%	Defined

Foresite Capital Management IV, LLC

$23,387,500

0.50%

1,250,000

Caption Management, LLC

$23,323,886

0.50%

1,246,600

VANGUARD FIDUCIARY TRUST CO

$22,901,152

0.49%

1,224,006

UBS Group AG

$20,487,074

0.44%

1,094,980

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	4,947	$92,558	0.5%	Defined
UBS AG	1,055,966	$19,757,123	96.4%	Defined
UBS Switzerland AG	34,067	$637,393	3.1%	Defined

FIRST TRUST ADVISORS LP

$20,115,607

0.43%

1,075,126

Affinity Asset Advisors, LLC

$19,645,500

0.42%

1,050,000

Frazier Life Sciences Management, L.P.

$19,003,616

0.41%

1,015,693

Squadron Capital Management LLC

$18,148,700

0.39%

970,000

Connor, Clark & Lunn Investment Management Ltd.

$17,993,443

0.38%

961,702

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	961,215	$17,984,332	99.9%	Sole
Held directly	487	$9,111	0.1%	Sole

Woodline Partners LP

$17,394,537

0.37%

929,692

JPMORGAN CHASE & CO

$14,999,001

0.32%

801,657

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	110,070	$2,059,409	13.7%	Defined
J.P. Morgan Investment Management Inc.	675,716	$12,642,646	84.3%	Defined
J.P. Morgan Securities plc	15,871	$296,946	2.0%	Defined

Timothy G. Youngquist 2020 Irrevocable Trust

$14,995,391

0.32%

801,464

RAYMOND JAMES FINANCIAL INC

$14,651,145

0.31%

783,065

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	86,293	$1,614,542	11.0%	Defined
Raymond James Financial Services Advisors, Inc.	196,828	$3,682,651	25.1%	Defined
EAGLE ASSET MANAGEMENT INC joint	499,944	$9,353,952	63.8%	Defined

CONGRESS ASSET MANAGEMENT CO

$14,070,769

0.30%

779,544

JUPITER ASSET MANAGEMENT LTD

$13,463,266

0.29%

719,576

TWO SIGMA INVESTMENTS, LP

$13,114,231

0.28%

700,921

EcoR1 Capital, LLC

$13,058,607

0.28%

697,948

Invesco Ltd.

$12,958,245

0.28%

692,584

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	23,959	$448,272	3.5%	Defined
Invesco Trust Co joint	64,402	$1,204,961	9.3%	Defined
Invesco Capital Management LLC	604,223	$11,305,012	87.2%	Defined

MILLENNIUM MANAGEMENT LLC

$11,070,239

0.24%

591,675

Tetragon Partners GP Ltd

$10,670,518

0.23%

570,311

Rhenman & Partners Asset Management AB

$10,589,860

0.23%

566,000

CITADEL ADVISORS LLC

$10,503,794

0.22%

561,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	561,400	$10,503,794	100.0%	Defined

ArrowMark Colorado Holdings LLC

$10,124,430

0.22%

541,124

HighVista Strategies LLC

$9,471,656

0.20%

506,235

AMERIPRISE FINANCIAL INC

$8,982,221

0.19%

480,076

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	478,926	$8,960,705	99.8%	Defined
Ameriprise Financial Services, LLC	1,150	$21,516	0.2%	Defined

JANE STREET GROUP, LLC

$8,920,928

0.19%

476,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	476,800	$8,920,928	100.0%	Defined

CITADEL ADVISORS LLC

$8,862,590

0.19%

473,682

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	60,048	$1,123,498	12.7%	Defined
Held directly	413,634	$7,739,092	87.3%	Defined

Bank of New York Mellon Corp

$8,658,163

0.19%

462,756

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	153,733	$2,876,344	33.2%	Defined
The Bank of New York Mellon	299,610	$5,605,703	64.7%	Defined
BNY Mellon, NA joint	2,865	$53,604	0.6%	Defined
BNY Mellon Advisors, Inc. joint	6,547	$122,494	1.4%	Other
Held directly	1	$18	0.0%	Defined

BESSEMER GROUP INC

$8,566,728

0.18%

457,869

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BESSEMER TRUST Co NATIONAL ASSOCIATION	457,869	$8,566,728	100.0%	Defined

Boxer Capital Management, LLC

$8,419,500

0.18%

450,000

Eversept Partners, LP

$8,126,014

0.17%

434,314

MOORE CAPITAL MANAGEMENT, LP

$7,746,033

0.17%

414,005

LORD, ABBETT & CO. LLC

$7,684,627

0.16%

410,723

Nuveen, LLC

$7,347,247

0.16%

392,691

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	57,455	$1,074,982	14.6%	Defined
TEACHERS ADVISORS, LLC joint	335,236	$6,272,265	85.4%	Defined

Aberdeen Group plc

$6,963,281

0.15%

372,169

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	372,169	$6,963,281	100.0%	Defined

Russell Investments Group, Ltd.

$6,801,512

0.15%

363,523

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	196,927	$3,684,503	54.2%	Defined
Russell Investments Capital, LLC	88,218	$1,650,558	24.3%	Defined
Russell Investments France SAS	25,739	$481,576	7.1%	Defined
Russell Investments Trust Company	52,639	$984,875	14.5%	Defined

ADAR1 Capital Management, LLC

$6,704,410

0.14%

358,333

Logos Global Management LP

$6,548,500

0.14%

350,000

Duquesne Family Office LLC

$6,529,790

0.14%

349,000

TD Asset Management Inc

$6,510,069

0.14%

347,946

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$5,207,494

0.11%

278,327

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	4,089	$76,505	1.5%	Defined
UBS Asset Management Switzerland AG	209,706	$3,923,599	75.3%	Defined
UBS Asset Management (UK) Ltd.	35,056	$655,896	12.6%	Defined
Held directly	29,476	$551,494	10.6%	Defined

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$4,930,197

0.11%

263,506

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	263,506	$4,930,197	100.0%	Defined

CITADEL ADVISORS LLC

$4,714,920

0.10%

252,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	252,000	$4,714,920	100.0%	Defined

CITIGROUP INC

$4,644,438

0.10%

248,233

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	248,233	$4,644,438	100.0%	Defined

RHUMBLINE ADVISERS

$4,510,531

0.10%

241,076

VOYA INVESTMENT MANAGEMENT LLC

$4,468,621

0.10%

238,836

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	238,836	$4,468,621	100.0%	Defined

Swiss National Bank

$4,426,786

0.09%

236,600

SPHERA FUNDS MANAGEMENT LTD.

$4,375,071

0.09%

233,836

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	233,836	$4,375,071	100.0%	Defined

DIADEMA PARTNERS LP

$4,315,966

0.09%

230,677

ALPS ADVISORS INC

$4,123,422

0.09%

220,386

WELLS FARGO & COMPANY/MN

$3,811,918

0.08%

203,737

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	144,879	$2,710,686	71.1%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	40,774	$762,881	20.0%	Defined
WELLS FARGO CLEARING SERVICES, LLC	18,084	$338,351	8.9%	Defined

JANE STREET GROUP, LLC

$3,745,742

0.08%

200,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	200,200	$3,745,742	100.0%	Defined

RENAISSANCE TECHNOLOGIES LLC

$3,599,785

0.08%

192,399

ExodusPoint Capital Management, LP

$3,445,970

0.07%

184,178

Seven Fleet Capital Management LP

$3,334,533

0.07%

178,222

Tema ETFs LLC

$3,307,591

0.07%

176,782

Tidal Investments LLC

$3,307,591

0.07%

176,782

Rafferty Asset Management, LLC

$3,270,227

0.07%

174,785

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$3,179,652

0.07%

169,944

Caption Management, LLC

$3,087,150

0.07%

165,000

DEUTSCHE BANK AG\

$3,069,113

0.07%

164,036

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	2,396	$44,829	1.5%	Defined
DWS Investments UK Ltd	161,640	$3,024,284	98.5%	Defined

Verition Fund Management LLC

$2,956,498

0.06%

158,017

WELLINGTON MANAGEMENT GROUP LLP

$2,935,709

0.06%

156,906

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	130,784	$2,446,968	83.4%	Defined
Wellington Managment Canada LLC	1,491	$27,896	1.0%	Defined
Wellington Trust Company, NA joint	21,218	$396,988	13.5%	Defined
Wellington Management Europe GmbH	3,413	$63,857	2.2%	Defined

Key facts CIK 1812364 CUSIP 75943R102 13F (30d) 8 filings 7 filers Visit website Investor relations