RVMD · Revolution Medicines, Inc.

$221.15 +5.71 (+2.65%) At close · Aug 27

Market Cap

$46.18B

214.34M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 697

Total Value: $40,957,141,197

Total Shares: 228,876,667

Showing 1–100 of 746 holdings by value · page 1 of 8

Institutional Ownership Trend

26 quarters

Superinvestors Holding RVMD

All superinvestors →

Stanley Druckenmiller $74,834,653 Joel Greenblatt $22,605,070

Holder Concentration

Across 697 13F filers · Δ vs Mar 31, 2026

Top Holder

6.3%

−0.4 pts

Top 5

28.2%

+2.4 pts

Top 10

47.4%

+3.9 pts

HHI

283

Broadly held+30

Quarterly Activity

vs Mar 31, 2026

New

243

Increased

238

Decreased

160

Sold Out

Unchanged

Holder count: +173

Institutional value: +106.3%

Shares held: +5.7%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mid Darwin Global Management, Ltd.	+8,418,804	10,629,822
Mega FMR LLC	+3,736,108	12,200,422
Mega JPMORGAN CHASE & CO	+2,996,673	3,298,066
Mega BlackRock, Inc.	+2,483,084	13,695,790
Large BAKER BROS. ADVISORS LP	+1,888,000	11,443,357

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large ADAGE CAPITAL PARTNERS GP, L.L.C.	−4,878,385	1,097,226
Mega WELLINGTON MANAGEMENT GROUP LLP	−2,184,404	3,843,415
Mid Vestal Point Capital, LP	−1,925,000	450,000
Small Abu Dhabi Investment Council Co P.J.S.C	−1,603,139	136,720
Mid Logos Global Management LP	−1,300,000	700,000

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mega Jupiter Topco LLC	10,736,145	$2,010,665,232
Mega Capital World Investors	4,008,244	$750,663,936
Mega NORGES BANK	2,157,479	$404,052,667
Mega MASSACHUSETTS FINANCIAL SERVICES CO /MA/	2,012,317	$376,866,725
Large 1832 Asset Management L.P.	309,200	$57,906,976

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mega JANUS HENDERSON GROUP PLC	9,766,496	$949,791,733
Mid Frazier Life Sciences Management, L.P.	675,686	$65,710,463
Small Lunate Capital Ltd	999,050	$53,395,112
Large VOLORIDGE INVESTMENT MANAGEMENT, LLC	368,325	$35,819,606
Small Ikarian Capital, LLC	258,142	$25,104,309

Filter: New 243 Increased 238 Reduced 160 Sold out 70 Unchanged 56

Showing 100 of 746

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

BlackRock, Inc.

$2,564,947,540

6.26%

13,695,790

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	292,118	$54,707,859	2.1%	Sole
BlackRock Investment Management (Australia) Ltd	84,220	$15,772,721	0.6%	Sole
BlackRock Asset Management Canada Ltd	20,680	$3,872,950	0.2%	Sole
BLACKROCK (SINGAPORE) LTD.	11,975	$2,242,678	0.1%	Sole
BlackRock Asset Management North Asia Ltd	19,829	$3,713,575	0.1%	Sole
BlackRock Investment Management, LLC	215,477	$40,354,532	1.6%	Sole
BLACKROCK ADVISORS LLC	523,642	$98,067,673	3.8%	Sole
BlackRock Fund Advisors	5,531,627	$1,035,963,104	40.4%	Sole
BlackRock Institutional Trust Company, N.A.	4,935,466	$924,314,072	36.0%	Sole
BlackRock Japan Co. Ltd	178,103	$33,355,129	1.3%	Sole
BlackRock Fund Managers Ltd.	8,574	$1,605,738	0.1%	Sole
BlackRock Investment Management (UK) Ltd.	129,617	$24,274,671	0.9%	Sole
BlackRock (Netherlands) B.V.	172,434	$32,293,439	1.3%	Sole
BlackRock International, Ltd.	3,952	$740,130	0.0%	Sole
BlackRock Asset Management Ireland Ltd	958,930	$179,588,410	7.0%	Sole
BlackRock Advisors (UK) Ltd	8,257	$1,546,370	0.1%	Sole
BlackRock (Luxembourg) S.A.	387,392	$72,550,773	2.8%	Sole
BlackRock Life Ltd	19,884	$3,723,875	0.1%	Sole
BlackRock Asset Management Schweiz AG	6,031	$1,129,485	0.0%	Sole
Aperio Group, LLC	187,494	$35,113,876	1.4%	Sole
SpiderRock Advisors, LLC	88	$16,480	0.0%	Sole

FARALLON CAPITAL MANAGEMENT LLC

$2,537,793,074

6.20%

13,550,796

FMR LLC

$2,284,895,029

5.58%

12,200,422

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC joint	8,343,696	$1,562,607,386	68.4%	Defined
FIDELITY MANAGEMENT TRUST CO	3,427,839	$641,965,687	28.1%	Defined
STRATEGIC ADVISERS LLC	201,234	$37,687,103	1.6%	Defined
Fidelity Institutional Asset Management Trust Co	18,900	$3,539,592	0.2%	Defined
FIAM LLC	207,487	$38,858,165	1.7%	Defined
Fidelity Diversifying Solutions LLC	1,266	$237,096	0.0%	Defined

BAKER BROS. ADVISORS LP

$2,143,111,898

5.23%

11,443,357

Jupiter Topco LLC

$2,010,665,232

4.91%

10,736,145

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	108,145	$20,253,395	1.0%	Defined
JANUS HENDERSON INVESTORS US LLC	10,478,476	$1,962,408,985	97.6%	Defined
Held directly	149,524	$28,002,852	1.4%	Defined

Darwin Global Management, Ltd.

$1,990,753,064

4.86%

10,629,822

VANGUARD CAPITAL MANAGEMENT LLC

$1,702,124,432

4.16%

9,088,661

VANGUARD PORTFOLIO MANAGEMENT LLC

$1,553,460,444

3.79%

8,294,855

Nextech Invest, Ltd.

$1,423,531,573

3.48%

7,601,087

Paradigm Biocapital Advisors LP

$1,191,348,571

2.91%

6,361,323

UBS Group AG

$1,020,369,609

2.49%

5,448,364

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	143,250	$26,827,860	2.6%	Defined
UBS AG	5,299,393	$992,470,321	97.3%	Defined
UBS Switzerland AG	5,702	$1,067,870	0.1%	Defined
UBS Securities LLC	19	$3,558	0.0%	Defined

STATE STREET CORP

$917,119,711

2.24%

4,897,051

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS (JAPAN) CO., LTD. joint	4,897,051	$917,119,711	100.0%	Defined

Capital World Investors

$750,663,936

1.83%

4,008,244

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CAPITAL GROUP COMPANIES INC joint	4,008,244	$750,663,936	100.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$738,384,360

1.80%

3,942,676

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	512,471	$95,975,568	13.0%	Defined
Held directly	3,430,205	$642,408,792	87.0%	Defined

WELLINGTON MANAGEMENT GROUP LLP

$719,794,757

1.76%

3,843,415

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	3,401,005	$636,940,216	88.5%	Defined
Wellington Managment Canada LLC	32,195	$6,029,479	0.8%	Defined
Wellington Management Hong Kong Ltd	1,022	$191,400	0.0%	Defined
Wellington Management Japan Pte Ltd	5,144	$963,368	0.1%	Defined
Wellington Management Singapore Pte. Ltd.	47,627	$8,919,584	1.2%	Defined
Wellington Management International Ltd	66,949	$12,538,208	1.7%	Defined
Wellington Trust Company, NA joint	276,770	$51,833,485	7.2%	Defined
Wellington Management Australia Pty Ltd	12,703	$2,379,017	0.3%	Defined

JPMORGAN CHASE & CO

$617,661,794

1.51%

3,298,066

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Trust Co of Delaware	1,229	$230,167	0.0%	Other
JPMorgan Chase Bank, N.A.	355,966	$66,665,312	10.8%	Other
J.P. Morgan Investment Management Inc.	2,176,962	$407,701,442	66.0%	Other
J.P. Morgan Securities LLC	583,920	$109,356,536	17.7%	Defined
J.P. Morgan Securities plc	99,150	$18,568,812	3.0%	Defined
JPMorgan Asset Management (UK) Ltd	67,544	$12,649,640	2.0%	Defined
JPMorgan Asset Management (Canada) Inc.	5,079	$951,195	0.2%	Defined
JPMorgan Asset Management (Asia Pacific) Ltd	383	$71,728	0.0%	Defined
JPMorgan Asset Management (Japan) Ltd	4,271	$799,872	0.1%	Defined
55I, LLC	10	$1,872	0.0%	Other
J.P. MORGAN MANSART MANAGEMENT Ltd	3,552	$665,218	0.1%	Defined

BVF INC/IL

$555,315,164

1.36%

2,965,160

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BVF PARTNERS L P/IL	2,965,160	$555,315,164	100.0%	Defined

Alphabet Inc.

$551,842,806

1.35%

2,946,619

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GV Management Company, L.L.C.	2,946,619	$551,842,806	100.0%	Defined

Casdin Capital, LLC

$482,682,924

1.18%

2,577,333

DEERFIELD MANAGEMENT COMPANY, L.P.

$447,973,760

1.09%

2,392,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deerfield UGP, LLC	2,392,000	$447,973,760	100.0%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$447,655,945

1.09%

2,390,303

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	210,844	$39,486,864	8.8%	Defined
Held directly	2,179,459	$408,169,081	91.2%	Sole

Avoro Capital Advisors LLC

$430,182,160

1.05%

2,297,000

NORGES BANK

$404,052,667

0.99%

2,157,479

GOLDMAN SACHS GROUP INC

$399,487,154

0.98%

2,133,101

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	1,650,635	$309,130,922	77.4%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	481,176	$90,114,641	22.6%	Defined
Goldman Sachs Trust Company, N.A.	1,290	$241,591	0.1%	Defined

Nearwater Capital Markets, Ltd

$392,726,160

0.96%

2,097,000

MASSACHUSETTS FINANCIAL SERVICES CO /MA/

$376,866,725

0.92%

2,012,317

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MFS Institutional Advisors, Inc.	199,054	$37,278,833	9.9%	Defined
MFS Investment Management CO (LUX) S.A.R.L.	12,924	$2,420,406	0.6%	Defined
MFS Investment Management K.K.	11,862	$2,221,515	0.6%	Defined
MFS Heritage Trust CO	321,343	$60,181,117	16.0%	Defined
MFS INVESTMENT MANAGEMENT CANADA LTD	3,371	$631,320	0.2%	Defined
Held directly	1,463,763	$274,133,534	72.7%	Sole

Woodline Partners LP

$375,096,182

0.92%

2,002,863

Caligan Partners LP

$367,404,967

0.90%

1,961,795

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$359,020,441

0.88%

1,917,025

Integral Health Asset Management, LLC

$280,920,000

0.69%

1,500,000

FRANKLIN RESOURCES INC

$278,746,426

0.68%

1,488,394

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST CO INTERNATIONAL	32	$5,992	0.0%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	1,594	$298,524	0.1%	Defined
FRANKLIN ADVISERS INC	1,472,434	$275,757,439	98.9%	Defined
FRANKLIN ADVISORY SERVICES LLC	14,334	$2,684,471	1.0%	Defined

Holocene Advisors, LP

$254,563,898

0.62%

1,359,269

AQR CAPITAL MANAGEMENT LLC

$242,611,869

0.59%

1,295,450

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Petros Family Wealth, LLC	46	$8,614	0.0%	Other
KEB ASSET MANAGEMENT, LLC	46	$8,614	0.0%	Other
RF&L WEALTH MANAGEMENT, LLC	6	$1,123	0.0%	Other
Prism Planning Partners LLC	52	$9,738	0.0%	Other
Compound Planning, Inc.	10	$1,872	0.0%	Other
Arax Advisory Partners	1,078	$201,887	0.1%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	832	$155,816	0.1%	Other
Stokes Family Office, LLC	82	$15,356	0.0%	Other
NATIONAL MUTUAL FUNDS MANAGEMENT LTD	10,483	$1,963,256	0.8%	Other
Held directly	1,282,815	$240,245,593	99.0%	Defined

VANGUARD FIDUCIARY TRUST CO

$241,804,886

0.59%

1,291,141

NORTHERN TRUST CORP

$209,212,357

0.51%

1,117,110

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	955,744	$178,991,735	85.6%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	151,012	$28,281,526	13.5%	Defined
Northern Trust Asset Management Australia Pty Ltd	9,405	$1,761,368	0.8%	Defined
Northern Trust Co of Hong Kong Ltd	949	$177,728	0.1%	Defined

Rock Springs Capital Management LP

$206,983,728

0.51%

1,105,210

NATIONAL BANK OF CANADA /FI/

$205,263,562

0.50%

1,096,025

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NBC Global Finance Ltd	1,092,000	$204,509,760	99.6%	Defined
Manager 7	4,025	$753,802	0.4%	Defined

Bellevue Group AG

$196,272,061

0.48%

1,048,014

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BB Biotech AG joint	1,042,424	$195,225,166	99.5%	Defined
Bellevue Asset Management AG	5,590	$1,046,895	0.5%	Defined

AMERIPRISE FINANCIAL INC

$194,715,388

0.48%

1,039,702

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC joint	1,010,959	$189,332,401	97.2%	Defined
Ameriprise Trust Co	1,167	$218,555	0.1%	Defined
Ameriprise Financial Services, LLC	40	$7,491	0.0%	Defined
Ameriprise Bank, FSB	17	$3,183	0.0%	Defined
Columbia Threadneedle Management Ltd	27,519	$5,153,758	2.6%	Defined

Pictet Asset Management Holding SA

$190,069,348

0.46%

1,014,894

BANK OF AMERICA CORP /DE/

$184,266,849

0.45%

983,911

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	516,869	$96,799,226	52.5%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	117,240	$21,956,707	11.9%	Defined
BOFA SECURITIES, INC.	28,092	$5,261,069	2.9%	Defined
MERRILL LYNCH INTERNATIONAL	13,234	$2,478,463	1.3%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	306,236	$57,351,877	31.1%	Defined
BofA Securities Europe SA	2,240	$419,507	0.2%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$182,391,992

0.45%

973,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	973,900	$182,391,992	100.0%	Other

a16z Capital Management, L.L.C.

$172,503,420

0.42%

921,099

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$170,862,094

0.42%

912,335

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	100,967	$18,909,099	11.1%	Defined
UBS Asset Management Switzerland AG	257,228	$48,173,658	28.2%	Defined
UBS Asset Management (UK) Ltd.	487,728	$91,341,699	53.5%	Defined
Held directly	66,412	$12,437,638	7.3%	Defined

Siren, L.L.C.

$168,552,000

0.41%

900,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	900,000	$168,552,000	100.0%	Defined

DEUTSCHE BANK AG\

$166,308,196

0.41%

888,019

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deutsche Bank Trust Co Americas	4	$749	0.0%	Defined
DWS Investment GmbH	7,641	$1,431,006	0.9%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC	18,017	$3,374,223	2.0%	Defined
DWS Investments UK Ltd	833,913	$156,175,226	93.9%	Defined
DBX Advisors LLC	1,522	$285,040	0.2%	Defined
DWS International GmbH	26,922	$5,041,952	3.0%	Defined

MORGAN STANLEY

$156,987,266

0.38%

838,249

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	6,428	$1,203,835	0.8%	Defined
MORGAN STANLEY & CO. LLC	95,675	$17,918,014	11.4%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	173,314	$32,458,245	20.7%	Defined
MORGAN STANLEY AIP GP LP	7,664	$1,435,313	0.9%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	8,470	$1,586,261	1.0%	Defined
MORGAN STANLEY SMITH BARNEY LLC	169,009	$31,652,004	20.2%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	290,128	$54,335,171	34.6%	Defined
EATON VANCE MANAGEMENT	22,673	$4,246,199	2.7%	Defined
Calvert Research & Management	64,888	$12,152,224	7.7%	Defined

LORD, ABBETT & CO. LLC

$147,809,054

0.36%

789,241

DIMENSIONAL FUND ADVISORS LP

$142,975,918

0.35%

763,434

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	15,891	$2,976,066	2.1%	Defined
DFA Australia Ltd.	73,205	$13,709,832	9.6%	Defined
Dimensional Fund Advisors Pte. Ltd.	1,248	$233,725	0.2%	Defined
Dimensional Ireland Ltd	38,940	$7,292,683	5.1%	Defined
Held directly	634,150	$118,763,612	83.1%	Sole

TWO SIGMA INVESTMENTS, LP

$138,155,894

0.34%

737,697

Logos Global Management LP

$131,096,000

0.32%

700,000

Polar Capital Holdings Plc

$129,282,380

0.32%

690,316

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Polar Capital LLP	690,316	$129,282,380	100.0%	Defined

Caption Management, LLC

$126,938,384

0.31%

677,800

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$126,226,720

0.31%

674,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	674,000	$126,226,720	100.0%	Other

Alyeska Investment Group, L.P.

$123,469,771

0.30%

659,279

Bank of New York Mellon Corp

$112,565,759

0.27%

601,056

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNY Mellon Trust of Delaware joint	478	$89,519	0.1%	Defined
Mellon Investments Corporation joint	348,469	$65,261,272	58.0%	Defined
The Bank of New York Mellon	166,981	$31,272,201	27.8%	Defined
BNY Mellon, NA joint	48,472	$9,077,834	8.1%	Defined
BNY Mellon Advisors, Inc. joint	34,354	$6,433,816	5.7%	Defined
Newton Investment Management North America, LLC joint	2,296	$429,994	0.4%	Defined
Held directly	6	$1,123	0.0%	Defined

WESTFIELD CAPITAL MANAGEMENT CO LP

$112,521,756

0.27%

600,821

ADAGE CAPITAL PARTNERS GP, L.L.C.

$111,848,485

0.27%

597,226

CITADEL ADVISORS LLC

$110,477,595

0.27%

589,906

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	61,079	$11,438,875	10.4%	Defined
Held directly	528,827	$99,038,720	89.6%	Defined

T. Rowe Price Investment Management, Inc.

$108,506,660

0.26%

579,382

Invesco Ltd.

$108,301,586

0.26%

578,287

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	139,543	$26,133,611	24.1%	Defined
Invesco Trust Co joint	78,021	$14,611,772	13.5%	Defined
Invesco Asset Management (Japan) Limited	3,647	$683,010	0.6%	Defined
Invesco Capital Management LLC	357,076	$66,873,193	61.7%	Defined

DAFNA Capital Management LLC

$105,369,346

0.26%

562,630

Candriam S.C.A.

$104,201,093

0.25%

556,392

BNP PARIBAS ARBITRAGE, SA

$103,511,528

0.25%

552,710

MIC Capital Management UK LLP

$99,582,956

0.24%

531,733

PERCEPTIVE ADVISORS LLC

$98,808,928

0.24%

527,600

JANE STREET GROUP, LLC

$97,891,256

0.24%

522,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	522,700	$97,891,256	100.0%	Defined

Boxer Capital Management, LLC

$93,640,000

0.23%

500,000

MPM BIOIMPACT LLC

$92,232,216

0.23%

492,483

Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.

$89,722,102

0.22%

479,080

Nuveen, LLC

$89,001,259

0.22%

475,231

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	47,274	$8,853,473	9.9%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	136,438	$25,552,108	28.7%	Defined
TEACHERS ADVISORS, LLC joint	291,519	$54,595,678	61.3%	Defined

BOOTHBAY FUND MANAGEMENT, LLC

$87,232,589

0.21%

465,787

Swiss National Bank

$85,461,669

0.21%

456,331

CITADEL ADVISORS LLC

$85,193,672

0.21%

454,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	454,900	$85,193,672	100.0%	Defined

Vestal Point Capital, LP

$84,276,000

0.21%

450,000

First Turn Management, LLC

$77,778,694

0.19%

415,307

Checkpoint Capital L.P.

$76,850,909

0.19%

410,353

Duquesne Family Office LLC

$74,834,653

0.18%

399,587

Legal & General Group Plc

$71,422,223

0.17%

381,366

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	44,971	$8,422,168	11.8%	Defined
Legal & General Investment Management Ltd joint	336,395	$63,000,055	88.2%	Defined

GENERAL ATLANTIC, L.P.

$67,007,098

0.16%

357,791

California Public Employees Retirement System

$65,534,703

0.16%

349,929

Mass General Brigham, Inc

$64,441,362

0.16%

344,091

TCG Crossover Management, LLC

$63,843,564

0.16%

340,899

Qube Research & Technologies Ltd

$58,874,277

0.14%

314,365

1832 Asset Management L.P.

$57,906,976

0.14%

309,200

Sumitomo Mitsui Trust Group, Inc.

$57,363,864

0.14%

306,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Amova Asset Management Co., Ltd.	306,300	$57,363,864	100.0%	Defined

AIHC Capital Management Ltd

$56,770,748

0.14%

303,133

Integral Health Asset Management, LLC

$56,184,000

0.14%

300,000

JENNISON ASSOCIATES LLC

$52,613,132

0.13%

280,933

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	280,933	$52,613,132	100.0%	Defined

Patient Square Capital LP

$51,689,280

0.13%

276,000

National Pension Service

$51,240,557

0.13%

273,604

Amundi

$50,509,601

0.12%

269,701

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Amundi Asset Management joint	268,844	$50,349,103	99.7%	Defined
CPR Asset Management	857	$160,498	0.3%	Defined

BAILLIE GIFFORD & CO

$49,341,910

0.12%

263,466

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BAILLIE GIFFORD & CO LTD	64,850	$12,145,108	24.6%	Defined
BAILLIE GIFFORD OVERSEAS LTD	27,463	$5,143,270	10.4%	Defined
Baillie Gifford Investment Management (Europe) Ltd	37,707	$7,061,766	14.3%	Defined
Held directly	133,446	$24,991,766	50.7%	Sole

FRED ALGER MANAGEMENT, LLC

$48,593,167

0.12%

259,468

Chicago Capital, LLC

$47,165,906

0.12%

251,847

Caligan Partners LP

$47,157,104

0.12%

251,800

Affinity Asset Advisors, LLC

$46,820,000

0.11%

250,000

CITIGROUP INC

$46,267,897

0.11%

247,052

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citibank, N.A. joint	20	$3,745	0.0%	Defined
Citigroup Financial Products Inc. joint	247,032	$46,264,152	100.0%	Defined

Nicholas Investment Partners, LP

$45,807,564

0.11%

244,594

MARSHALL WACE, LLP

$45,798,200

0.11%

244,544

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	244,544	$45,798,200	100.0%	Other

Key facts CIK 1628171 CUSIP 76155X100 13F (30d) 549 filings 546 filers Visit website Investor relations