MNPR · Monopar Therapeutics

$113.72 +2.90 (+2.62%) At close · Aug 26

Market Cap

$745.55M

6.71M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 95

Total Value: $576,107,790

Total Shares: 6,222,139

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 95 13F filers · Δ vs Mar 31, 2026

Top Holder

21.1%

−0.0 pts

Top 5

47.6%

−0.0 pts

Top 10

65.7%

−2.6 pts

HHI

763

Broadly held−13

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +13

Institutional value: +68.6%

Shares held: -0.2%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mid TCG Crossover Management, LLC	+71,224	203,327
Large Driehaus Capital Management LLC	+50,884	84,040
Mega BlackRock, Inc.	+32,252	348,819
Mega NEUBERGER BERMAN GROUP LLC	+12,760	55,194
Mega GEODE CAPITAL MANAGEMENT, LLC	+12,660	112,578

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large ADAGE CAPITAL PARTNERS GP, L.L.C.	−100,000	209,195
Mega BANK OF AMERICA CORP /DE/	−56,449	3,250
Mid ADAR1 Capital Management, LLC	−46,683	217,595
Mega PRICE T ROWE ASSOCIATES INC /MD/	−44,003	3,699
Small Saturn V Capital Management LP	−33,650	311,976

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mega Jupiter Topco LLC	1,312,129	$121,490,024
Mid ORBIMED ADVISORS LLC	157,423	$14,575,795
Large Candriam S.C.A.	143,339	$13,271,758
Mid Longaeva Partners L.P.	55,834	$5,169,670
Small Ikarian Capital, LLC	47,861	$4,431,449

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mega JANUS HENDERSON GROUP PLC	1,317,410	$72,180,893
Small Sio Capital Management, LLC	173,506	$9,506,393
Large Walleye Capital LLC	63,119	$3,458,290
Small SILVERARC CAPITAL MANAGEMENT, LLC	43,488	$2,382,707
Mid Jump Financial, LLC	22,808	$1,249,650

Filter: New 30 Increased 32 Reduced 23 Sold out 17 Unchanged 10

Showing 95 of 95

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Jupiter Topco LLC

$121,490,024

21.09%

1,312,129

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS US LLC	1,312,129	$121,490,024	100.0%	Defined

RA CAPITAL MANAGEMENT, L.P.

$61,776,696

10.72%

667,207

BlackRock, Inc.

$32,297,148

5.61%

348,819

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	1,247	$115,459	0.4%	Sole
BlackRock Investment Management, LLC	13,224	$1,224,410	3.8%	Sole
BLACKROCK ADVISORS LLC	8,938	$827,569	2.6%	Sole
BlackRock Fund Advisors	176,521	$16,344,079	50.6%	Sole
BlackRock Institutional Trust Company, N.A.	134,696	$12,471,502	38.6%	Sole
Aperio Group, LLC	14,193	$1,314,129	4.1%	Sole

DEERFIELD MANAGEMENT COMPANY, L.P.

$29,975,549

5.20%

323,745

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deerfield UGP, LLC	323,745	$29,975,549	100.0%	Defined

Saturn V Capital Management LP

$28,885,857

5.01%

311,976

Siren, L.L.C.

$25,010,225

4.34%

270,118

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	270,118	$25,010,225	100.0%	Defined

ADAR1 Capital Management, LLC

$20,147,121

3.50%

217,595

Polar Capital Holdings Plc

$19,857,684

3.45%

214,469

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Polar Capital LLP	214,469	$19,857,684	100.0%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$19,417,141

3.37%

209,711

ADAGE CAPITAL PARTNERS GP, L.L.C.

$19,369,365

3.36%

209,195

TCG Crossover Management, LLC

$18,826,046

3.27%

203,327

WELLINGTON MANAGEMENT GROUP LLP

$14,669,679

2.55%

158,437

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	72,214	$6,686,294	45.6%	Defined
Wellington Management Singapore Pte. Ltd.	9,699	$898,030	6.1%	Defined
Wellington Management International Ltd	4,706	$435,728	3.0%	Defined
Wellington Trust Company, NA joint	70,291	$6,508,243	44.4%	Defined
Wellington Management Australia Pty Ltd	1,527	$141,384	1.0%	Defined

ORBIMED ADVISORS LLC

$14,575,795

2.53%

157,423

Candriam S.C.A.

$13,271,758

2.30%

143,339

Balyasny Asset Management L.P.

$12,457,336

2.16%

134,543

GEODE CAPITAL MANAGEMENT, LLC

$10,423,596

1.81%

112,578

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	15,671	$1,450,977	13.9%	Defined
Held directly	96,907	$8,972,619	86.1%	Defined

Alyeska Investment Group, L.P.

$9,259,000

1.61%

100,000

STATE STREET CORP

$8,569,297

1.49%

92,551

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	92,551	$8,569,297	100.0%	Defined

Vivo Capital, LLC

$8,379,395

1.45%

90,500

Driehaus Capital Management LLC

$7,781,263

1.35%

84,040

Bank of New York Mellon Corp

$7,124,056

1.24%

76,942

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	3,817	$353,416	5.0%	Defined
BNY Mellon Securities Corporation	1,172	$108,515	1.5%	Defined
The Bank of New York Mellon	7,409	$685,999	9.6%	Defined
BNY Mellon, NA joint	1	$92	0.0%	Defined
Newton Investment Management North America, LLC joint	64,541	$5,975,849	83.9%	Defined
Held directly	2	$185	0.0%	Defined

Vestal Point Capital, LP

$7,011,562

1.22%

75,727

Longaeva Partners L.P.

$5,169,670

0.90%

55,834

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Balyasny Asset Management L.P.	55,834	$5,169,670	100.0%	Other

NEUBERGER BERMAN GROUP LLC

$5,110,411

0.89%

55,194

MILLENNIUM MANAGEMENT LLC

$4,658,295

0.81%

50,311

VANGUARD PORTFOLIO MANAGEMENT LLC

$4,519,873

0.78%

48,816

Ikarian Capital, LLC

$4,431,449

0.77%

47,861

CITADEL ADVISORS LLC

$3,426,200

0.59%

37,004

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	37,004	$3,426,200	100.0%	Defined

NORTHERN TRUST CORP

$3,207,408

0.56%

34,641

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	33,933	$3,141,855	98.0%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	708	$65,553	2.0%	Other

DEUTSCHE BANK AG\

$2,871,030

0.50%

31,008

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS Investment GmbH	26,523	$2,455,764	85.5%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC	90	$8,333	0.3%	Defined
DWS Investments UK Ltd	4,395	$406,933	14.2%	Defined

STEMPOINT CAPITAL LP

$2,789,273

0.48%

30,125

VANGUARD FIDUCIARY TRUST CO

$2,618,445

0.45%

28,280

UBS Group AG

$2,523,910

0.44%

27,259

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	27,142	$2,513,077	99.6%	Defined
UBS Switzerland AG	117	$10,833	0.4%	Defined

MORGAN STANLEY

$1,659,118

0.29%

17,919

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	6	$555	0.0%	Defined
MORGAN STANLEY & CO. LLC	4,351	$402,859	24.3%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	1,493	$138,236	8.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	12,069	$1,117,468	67.4%	Defined

AMERIPRISE FINANCIAL INC

$1,648,102

0.29%

17,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	17,800	$1,648,102	100.0%	Defined

GOLDMAN SACHS GROUP INC

$1,496,346

0.26%

16,161

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	7,976	$738,497	49.4%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	8,185	$757,849	50.6%	Defined

Russell Investments Group, Ltd.

$1,374,960

0.24%

14,850

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	7,475	$692,109	50.3%	Defined
Russell Investments Capital, LLC	2,800	$259,252	18.9%	Defined
Russell Investments France SAS	1,778	$164,625	12.0%	Defined
Russell Investments Trust Company	2,797	$258,974	18.8%	Defined

BOOTHBAY FUND MANAGEMENT, LLC

$1,360,054

0.24%

14,689

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$1,291,908

0.22%

13,953

Ishara Investments LP

$1,138,857

0.20%

12,300

TWO SIGMA INVESTMENTS, LP

$1,134,412

0.20%

12,252

Trexquant Investment LP

$1,111,450

0.19%

12,004

Creative Planning

$719,238

0.12%

7,768

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	338	$31,295	4.4%	Defined
Held directly	7,430	$687,943	95.6%	Sole

GSA CAPITAL PARTNERS LLP

$697,387

0.12%

7,532

XTX Topco Ltd

$605,168

0.11%

6,536

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	6,536	$605,168	100.0%	Defined

Nuveen, LLC

$553,688

0.10%

5,980

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TEACHERS ADVISORS, LLC joint	5,980	$553,688	100.0%	Defined

BARCLAYS PLC

$540,077

0.09%

5,833

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	717	$66,387	12.3%	Defined
BARCLAYS CAPITAL INC.	5,116	$473,690	87.7%	Defined

RHUMBLINE ADVISERS

$521,281

0.09%

5,630

GERBER, LLC

$518,596

0.09%

5,601

RAYMOND JAMES FINANCIAL INC

$506,837

0.09%

5,474

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	5,474	$506,837	100.0%	Defined

Virtus Investment Advisers, LLC

$506,837

0.09%

5,474

STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM

$490,727

0.09%

5,300

ALLIANCEBERNSTEIN L.P.

$440,728

0.08%

4,760

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	4,760	$440,728	100.0%	Defined

WELLS FARGO & COMPANY/MN

$366,471

0.06%

3,958

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	3,812	$352,953	96.3%	Defined
WELLS FARGO CLEARING SERVICES, LLC	100	$9,259	2.5%	Defined
Wells Fargo Securities, LLC	46	$4,259	1.2%	Defined

Aquatic Capital Management LLC

$354,341

0.06%

3,827

PRICE T ROWE ASSOCIATES INC /MD/

$342,490

0.06%

3,699

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	3,699	$342,490	100.0%	Defined

Engineers Gate Manager LP

$322,120

0.06%

3,479

BANK OF AMERICA CORP /DE/

$300,917

0.05%

3,250

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	3,250	$300,917	100.0%	Defined

MetLife Investment Management, LLC

$269,251

0.05%

2,908

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	2,908	$269,251	100.0%	Defined

EP Wealth Advisors, LLC

$241,011

0.04%

2,603

Entropy Technologies, LP

$240,734

0.04%

2,600

JPMORGAN CHASE & CO

$232,030

0.04%

2,506

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	1,868	$172,958	74.5%	Defined
J.P. Morgan Investment Management Inc.	441	$40,832	17.6%	Defined
J.P. Morgan Securities plc	197	$18,240	7.9%	Defined

GABELLI FUNDS LLC

$231,475

0.04%

2,500

WINTON GROUP Ltd

$231,475

0.04%

2,500

AMERICAN CENTURY COMPANIES INC

$228,604

0.04%

2,469

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	2,469	$228,604	100.0%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$222,216

0.04%

2,400

Invesco Ltd.

$218,141

0.04%

2,356

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	573	$53,054	24.3%	Defined
Invesco Trust Co joint	1,783	$165,087	75.7%	Defined

Martin Investment Management, LLC

$215,456

0.04%

2,327

Schonfeld Strategic Advisors LLC

$213,882

0.04%

2,310

CITIGROUP INC

$193,327

0.03%

2,088

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	2,088	$193,327	100.0%	Defined

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$192,216

0.03%

2,076

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	2,076	$192,216	100.0%	Defined

DIADEMA PARTNERS LP

$150,921

0.03%

1,630

Vanguard Global Advisers, LLC

$143,792

0.02%

1,553

Quarry LP

$139,070

0.02%

1,502

Police & Firemen's Retirement System of New Jersey

$135,922

0.02%

1,468

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	1,468	$135,922	100.0%	Defined

MEEDER ASSET MANAGEMENT INC

$128,607

0.02%

1,389

NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO

$124,996

0.02%

1,350

Persistent Asset Partners Ltd

$117,681

0.02%

1,271

BNP PARIBAS ARBITRAGE, SA

$68,609

0.01%

741

NewEdge Advisors, LLC

$55,554

0.01%

600

FMR LLC

$49,072

0.01%

530

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	530	$49,072	100.0%	Defined

Legal & General Group Plc

$43,054

0.01%

465

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	465	$43,054	100.0%	Defined

Ameritas Investment Partners, Inc.

$37,869

0.01%

409

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	409	$37,869	100.0%	Other

Tower Research Capital LLC (TRC)

$31,943

0.01%

345

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	345	$31,943	100.0%	Defined

ROYAL BANK OF CANADA

$12,592

0.00%

136

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	136	$12,592	100.0%	Defined

Allworth Financial LP

$10,277

0.00%

111

C M BIDWELL & ASSOCIATES LTD

$8,703

0.00%

Sterling Capital Management LLC

$6,666

0.00%

Global Retirement Partners, LLC

$2,962

0.00%

GAMMA Investing LLC

$2,314

0.00%

Farther Finance Advisors, LLC

$2,222

0.00%

PNC FINANCIAL SERVICES GROUP, INC.

$555

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	6	$555	100.0%	Defined

US BANCORP \DE\

$555

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
US BANK NATIONAL ASSOCIATION	6	$555	100.0%	Other

Arax Advisory Partners

$277

0.00%

Integrated Wealth Concepts LLC

$92

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS US LLC	1,317,410	$72,180,893	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Leap GP LLC joint	22,808	$1,249,650	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	21,754	$1,191,901	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI TRUST CO	7,582	$415,417	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	4,572	$250,499	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	4,137	$226,666	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	3,673	$201,243	100.0%	Other

Key facts CIK 1645469 CUSIP 61023L207 13F (30d) 93 filings 92 filers Visit website Investor relations