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Equibles

IRON

Disc Medicine, Inc.

Company with tickers: IRON

CIK
1816736
CUSIP
254604101
Shares Outstanding
38,199,089
Investor Relations
https://ir.discmedicine.com/
13F Activity (30d)
11 filings 7 filers

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 205
Total Value: $2,690,838,725
Total Shares: 42,083,811
Showing 1–100 of 210 holdings by value · page 1 of 3

Institutional Ownership Trend

20 quarters

Holder Concentration

Across 205 13F filers · Δ vs Dec 31, 2025
Top Holder
13.3%
Dec 2024 → Mar 2026 · range 9.4% – 14.4%
−0.9 pts
Top 5
32.7%
Dec 2024 → Mar 2026 · range 31.6% – 36.7%
−1.6 pts
Top 10
49.7%
Dec 2024 → Mar 2026 · range 49.7% – 61.3%
−3.0 pts
HHI
400
Dec 2024 → Mar 2026 · range 381 – 455
Broadly held−29

Quarterly Activity

vs Dec 31, 2025
New
47
Increased
82
Decreased
44
Sold Out
41
Unchanged
32
Holder count: +6
Institutional value: -11.8%
Shares held: +9.5%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mid BVF INC/IL +622,312 1,272,312
Mega STATE STREET CORP +510,253 1,698,244
Mid RA CAPITAL MANAGEMENT, L.P. +474,089 2,450,221
Small Opaleye Management Inc. +221,000 421,000
Mega WELLINGTON MANAGEMENT GROUP LLP +217,102 1,735,376

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mega JPMORGAN CHASE & CO −209,647 1,371,480
Small Checkpoint Capital L.P. −166,331 286,661
Mega PRICE T ROWE ASSOCIATES INC /MD/ −148,655 1,549,350
Mega MILLENNIUM MANAGEMENT LLC −125,520 83,259
Mega GOLDMAN SACHS GROUP INC −114,353 639,842

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 1,375,430 $87,944,994
Mid TCG Crossover Management, LLC 1,341,862 $85,798,656
Mid Bellevue Group AG 459,314 $29,368,537
Large Caption Management, LLC 300,000 $19,182,000
Small Octagon Capital Advisors LP 270,000 $17,263,800

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 1,767,680 $140,371,466
Mid First Light Asset Management, LLC 523,167 $41,544,691
Mid PERCEPTIVE ADVISORS LLC 450,743 $35,793,501
Small GREAT POINT PARTNERS LLC 250,000 $19,852,500
Large Balyasny Asset Management L.P. 221,761 $17,610,041
Filter: New 47 Increased 82 Reduced 44 Sold out 41 Unchanged 32
Showing 100 of 210
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mega FMR LLC $357,226,000 13.28% 5,586,894
Mid RA CAPITAL MANAGEMENT, L.P. $156,667,130 5.82% 2,450,221
Mega BlackRock, Inc. $145,388,748 5.40% 2,273,831
Mega WELLINGTON MANAGEMENT GROUP LLP $110,959,937 4.12% 1,735,376
Mega STATE STREET CORP $108,585,721 4.04% 1,698,244
Mega PRICE T ROWE ASSOCIATES INC /MD/ $99,065,438 3.68% 1,549,350
Small Atlas Venture Life Science Advisors, LLC $96,797,167 3.60% 1,513,875
Mega VANGUARD CAPITAL MANAGEMENT LLC $87,944,994 3.27% 1,375,430
Mega JPMORGAN CHASE & CO $87,692,428 3.26% 1,371,480
Mid Frazier Life Sciences Management, L.P. $86,629,236 3.22% 1,354,852
Mid TCG Crossover Management, LLC $85,798,656 3.19% 1,341,862
Mid BVF INC/IL $81,351,629 3.02% 1,272,312
Mid ORBIMED ADVISORS LLC $68,259,147 2.54% 1,067,550
Mid Siren, L.L.C. $63,198,359 2.35% 988,401
Large Woodline Partners LP $61,272,487 2.28% 958,281
Mega GEODE CAPITAL MANAGEMENT, LLC $47,585,554 1.77% 744,222
Mid Vestal Point Capital, LP $44,758,000 1.66% 700,000
Mid DEERFIELD MANAGEMENT COMPANY, L.P. $42,008,580 1.56% 657,000
Mega GOLDMAN SACHS GROUP INC $40,911,496 1.52% 639,842
Mega JENNISON ASSOCIATES LLC $39,027,825 1.45% 610,382
Mid Logos Global Management LP $35,806,400 1.33% 560,000
Large Assenagon Asset Management S.A. $34,927,033 1.30% 546,247
Mid ARMISTICE CAPITAL, LLC $34,271,840 1.27% 536,000
Mid Bellevue Group AG $29,368,537 1.09% 459,314
Small Saturn V Capital Management LP $28,768,268 1.07% 449,926
Small Opaleye Management Inc. $26,918,740 1.00% 421,000
Small Palo Alto Investors LP $25,685,912 0.95% 401,719
Mid EVENTIDE ASSET MANAGEMENT, LLC $25,292,873 0.94% 395,572
Mega DIMENSIONAL FUND ADVISORS LP $25,220,938 0.94% 394,447
Large Pictet Asset Management Holding SA $24,745,099 0.92% 387,005
Large Aberdeen Group plc $24,016,759 0.89% 375,614
Small Foresite Capital Management V, LLC $23,917,971 0.89% 374,069
Large BAKER BROS. ADVISORS LP $22,357,068 0.83% 349,657
Large LOOMIS SAYLES & CO L P $20,283,174 0.75% 317,222
Large Caption Management, LLC $19,182,000 0.71% 300,000
Small Checkpoint Capital L.P. $18,329,104 0.68% 286,661
Small Octagon Capital Advisors LP $17,263,800 0.64% 270,000
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $16,061,408 0.60% 251,195
Mega NORTHERN TRUST CORP Bank $15,805,645 0.59% 247,195
Mega VANGUARD FIDUCIARY TRUST CO Bank $13,902,857 0.52% 217,436
Mega Bank of New York Mellon Corp Bank $13,105,649 0.49% 204,968
Small SILVERARC CAPITAL MANAGEMENT, LLC $12,534,030 0.47% 196,028
Large Ensign Peak Advisors, Inc $12,243,678 0.46% 191,487
Mid Integral Health Asset Management, LLC $10,869,800 0.40% 170,000
Mega BANK OF AMERICA CORP /DE/ Bank $10,663,592 0.40% 166,775
Mid Bain Capital Life Sciences Investors, LLC $9,030,501 0.34% 141,234
Mega BNP PARIBAS ARBITRAGE, SA $8,167,503 0.30% 127,737
Large Alyeska Investment Group, L.P. $7,992,500 0.30% 125,000
Small Catalio Capital Management, LP $7,863,213 0.29% 122,978
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $7,090,304 0.26% 110,890
Mid KENNEDY CAPITAL MANAGEMENT LLC $6,923,806 0.26% 108,286
Small Atle Fund Management AB $6,857,884 0.25% 107,255
Mega UBS Group AG $6,305,825 0.23% 98,621
Mega CITADEL ADVISORS LLC $6,261,644 0.23% 97,930
Large DNB Asset Management AS $6,186,514 0.23% 96,755
Mega MORGAN STANLEY $6,027,236 0.22% 94,264
Mega MILLENNIUM MANAGEMENT LLC $5,323,580 0.20% 83,259
Mid Jump Financial, LLC $5,232,146 0.19% 81,829
Mid Sofinnova Investments, Inc. $5,007,780 0.19% 78,320
Large Freestone Grove Partners LP $4,391,846 0.16% 68,687
Mid iA Global Asset Management Inc. $4,235,577 0.16% 66,243
Small Sio Capital Management, LLC $4,169,079 0.15% 65,203
Mid Casdin Capital, LLC $4,156,100 0.15% 65,000
Small KVP Capital Advisors, LP $3,724,505 0.14% 58,250
Mid MOORE CAPITAL MANAGEMENT, LP $3,695,476 0.14% 57,796
Large Rafferty Asset Management, LLC $3,444,383 0.13% 53,869
Small SPHERA FUNDS MANAGEMENT LTD. $3,423,219 0.13% 53,538
Small NEXTBio Capital Management LP $3,366,760 0.13% 52,655
Mega Nuveen, LLC $3,285,237 0.12% 51,380
Mega SCHRODER INVESTMENT MANAGEMENT GROUP $3,258,318 0.12% 50,959
Mid Burkehill Global Management, LP $3,197,000 0.12% 50,000
Mega Swiss National Bank Bank $3,069,120 0.11% 48,000
Mega AMERIPRISE FINANCIAL INC $2,930,817 0.11% 45,837
Mega RAYMOND JAMES FINANCIAL INC $2,858,115 0.11% 44,700
Mid Nantahala Capital Management, LLC $2,621,540 0.10% 41,000
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. $2,551,845 0.09% 39,910
Large LAZARD ASSET MANAGEMENT LLC $2,519,236 0.09% 39,400
Large Universal- Beteiligungs- und Servicegesellschaft mbH $2,430,103 0.09% 38,006
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,346,598 0.09% 36,700
Mid SEVEN GRAND MANAGERS, LLC $2,237,900 0.08% 35,000
Mid XTX Topco Ltd $2,200,686 0.08% 34,418
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension $2,198,385 0.08% 34,382
Mega BARCLAYS PLC $2,127,091 0.08% 33,267
Mega RHUMBLINE ADVISERS $2,113,728 0.08% 33,058
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $2,077,602 0.08% 32,493
Mid Brevan Howard Capital Management LP $2,072,039 0.08% 32,406
Large RENAISSANCE TECHNOLOGIES LLC $2,034,570 0.08% 31,820
Large Squarepoint Ops LLC $2,027,473 0.08% 31,709
Large ALPS ADVISORS INC $1,985,848 0.07% 31,058
Large TUDOR INVESTMENT CORP ET AL $1,982,267 0.07% 31,002
Mega Invesco Ltd. $1,958,991 0.07% 30,638
Mega TD Asset Management Inc $1,948,635 0.07% 30,476
Large RTW INVESTMENTS, LP $1,918,200 0.07% 30,000
Mega VICTORY CAPITAL MANAGEMENT INC $1,868,198 0.07% 29,218
Mega BANK OF MONTREAL /CAN/ Bank $1,839,744 0.07% 28,773
Mid Nantahala Capital Management, LLC $1,640,252 0.06% 25,653
Mega PNC FINANCIAL SERVICES GROUP, INC. $1,617,168 0.06% 25,292
Mega ALLIANCEBERNSTEIN L.P. $1,569,087 0.06% 24,540
Mega DEUTSCHE BANK AG\ Bank $1,560,199 0.06% 24,401
Mid PROFUND ADVISORS LLC $1,532,769 0.06% 23,972

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