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IRON · Disc Medicine, Inc.

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$80.00 -3.23 (-3.88%) At close · Nov 13
Market Cap
$3.64B
Shares
45.54M
Volume · Nov 13 779.99K Avg daily vol (3M) 922.5K

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$80.00 Open$83.00 Day$79.73–83.00 52W close$55.74–94.11 Avg vol 30d1.4M Short int6.9M · 15.1% of shares · 3.2d Short vol58% Last earningsOct 19, 2026 DataAug 2020–Nov 2026 Filing10-Q · Nov 5

Up next

Dec 25, 2026 Est · unconfirmed · in 6 wks

Latest documents

2026
Nov 9
Investor event
Apollo hit all endpoints; two assets advancing

Disc Medicines reported that its phase three Apollo study hit all primary and secondary endpoints and plans to launch the porphyria therapy next year; two phase two assets are expected to enter phase three studies.

5 source passages
host John Quizzle, CEO of Disc Medicines we had a phenomenal phase three readout for our lead program to address rare porphyria So why don't we start with the Apollo study, obviously hit all primary and secondary endpoints. next year at this time, if all goes well, we'll be a commercial company marketing and launching the Bit of Hurt and Project in Porphyria. we have a pipeline that's also read out with great phase two proof of concept data, all presumably progressing towards phase three trials Open the document at this passage
Nov 5
Quarterly report 10-Q FY2026 Q3, ended Sep 30
Bitopertin Phase 3 succeeds; cash runway extends into 2030

Disc Medicine reported positive APOLLO Phase 3 results for bitopertin and plans an NDA resubmission by the end of 2026. Cash, cash equivalents and marketable securities totaled $682.8 million at September 30, 2026, funding is expected into 2030.

Net loss $59.54M Diluted EPS -$1.53
Read from the MD&A section
4 source passages
In October 2026, we announced positive topline results from APOLLO, a randomized, double-blind, pivotal Phase 3 trial evaluating the safety and efficacy of bitopertin versus placebo in adults and adolescents aged 12 or older with EPP or XLP. With the positive topline results from APOLLO, we plan to engage with the FDA and resubmit an NDA by the end of 2026, with an FDA decision anticipated by mid-2027. As of September 30, 2026, we had cash, cash equivalents and marketable securities of $682.8 million. We believe that our cash, cash equivalents and marketable securities, including the net proceeds of our October 2026 underwritten public offering, will be sufficient to fund our current operating and capital expenditure plans and our debt service obligations into 2030, without taking into account any potential net cash inflows from bitopertin or any other marketed product, if approved during such period. Open the document at this passage
Nov 5
Current report 8-K
APOLLO succeeds; bitopertin NDA resubmission planned by end of 2026

Disc Medicine’s APOLLO trial of bitopertin met all primary and secondary endpoints in EPP; NDA resubmission is planned by end of 2026, while approximately $486 million in October 2026 offering proceeds extend cash runway into 2030.

Financial results
4 source passages
Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from serious hematologic diseases Pivotal Phase 3 APOLLO trial of bitopertin in erythropoietic protoporphyria (EPP) successfully met all primary and secondary endpoints Bitopertin NDA resubmission planned by end of 2026, with an FDA decision for potential approval in EPP anticipated by mid-2027 Strong financial position ending Q3 with approximately $683 million in cash, cash equivalents, and marketable securities; completed a public offering in October 2026, with net proceeds of approximately $486 million extending cash runway into 2030 Open the document at this passage
Oct 22
Current report 8-K Events of Oct 19
Entered into a material agreement, Financial results, Other events

Disc Medicine, Inc. closed an underwritten offering on October 22, 2026 of 6,000,000 common shares at $75.00 per share, with expected net proceeds of approximately $422.4 million. Preliminary cash, cash equivalents and marketable securities were approximately $682.8 million as of September 30, 2026.

Read from the first part of this long document
Oct 19
Current report 8-K
Regulation FD disclosure, Other events

Disc Medicine announced positive Phase 3 APOLLO topline results for bitopertin in erythropoietic protoporphyria, meeting all primary and secondary endpoints, and plans to resubmit an NDA to the FDA by end of 2026 with a decision expected by mid-2027.

All documents

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
—
Trailing 12 months
Net income (TTM)
−$243.10M
Trailing 12 months
Revenue growth YoY
—
Year over year
Operating margin
—
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
-5.2%
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$623.07M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+10.6%
Year over year · more shares
Price change (1Y)
-8.1%
Trailing year
Short interest
15.1%
Latest settlement · 3.2 days to cover
View all 125 metrics

Equibles Rating

blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Buy Momentum Very Strong Sentiment Bullish Fundamentals Weak Quant / Vol Very High
Market backdrop VIX 19.3 · elevated Equity put/call 0.63
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg +13%
above
Price vs 50-day avg +12%
above
RSI (14) 54
neutral
MACD trend Positive
52-week position 63%
mid-range
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Very Strong
1-month return +41%
trailing
6-month return +17%
trailing
YTD return +1%
this year
Relative strength +17%
vs S&P · 6-mo
Sentiment
smart money
Bullish
Trend (MA cross) No cross
50d $72 › 200d $71 — 50d above 200d
Institutional flow Accumulating
168 of 224 funds reported for Sep 30 · net +1.1M sh shares · +26 new
Insider flow Distributing
Net -$1.9M over 90 days · 100% sells
Short interest Falling
15.07% of shares out · ▼ -8.0% MoM · 3.2 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
224 holders — near 3-yr high, broad support
Squeeze score 59
elevated · 0–100
Fundamentals
Weak
EPS growth −52%
Y/Y
Free cash flow $-181.3M
Balance sheet $62.0M
net cash
Quant / Vol
risk profile
Very High
Volatility 64%
annualized · 1-yr
Max drawdown −41%
past year
ATR 5.1%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Latest guidance · from the 8-K filed Oct 22, 2026
Aggregate gross proceeds · from this offering $450M

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Buy
0 · 4 · 3
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+13% Bullish
Price vs 50-day avg
+12% Bullish
RSI (14)
54 Neutral
MACD trend
Positive Bullish
52-week position
63% Neutral
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Bullish · 3 of 6
Trend (MA cross) No cross
50d $72 › 200d $71 — 50d above 200d
Institutional flow Accumulating
168 of 224 funds reported for Sep 30 · net +1.1M sh shares · +26 new
Insider flow Distributing
Net -$1.9M over 90 days · 100% sells
Short interest Falling
15.07% of shares out · ▼ -8.0% MoM · 3.2 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
224 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $56 Now $80 · 63% Range high $94
vs 200-day avg +13% vs 50-day avg +12%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
IRON
Disc Medicine, Inc.
this stock
$3.64B +0.7% — — 15.1%
VRTX
Vertex Pharmaceuticals Inc
$136.56B +18.8% +46.2% 34.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$98.84B +23.8% +20.8% 21.1 2.1%
MRNA
Moderna, Inc.
$90.38B +657.4% +4.3% — 8.2%
CSLLY
Csl Ltd
$66.05B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
234
% held
97.3%
Reported
168 of 224
Top holder
FMR LLC
Held Float
View
Held by Funds
Fund positions
229
View
Short & Settlement
Short Interest Falling
Shares short
6.9M
Days to cover
3.2d
Change
-594.9K sh
View
Short Volume
Short vol %
58%
As of
Nov 13, 2026
Short Total
View
Fails to Deliver
FTD shares
643
Value
$38.9K
As of
Oct 13, 2026
View
Off-Exchange
Off-exchange %
56.0%
Week of
Oct 5, 2026
Off-exch Lit
View
Smart Money
Insider Trades Net selling
Net (90d)
-$1.9M
Buyers / Sellers
0 / 1
Buyers Sellers
View
Financials
Financials
Net income (FY)
$-212.2M
EPS diluted
$-6.01
View
Filings
SEC Filings
Latest
Investor Event Transcript
Filed
Nov 9, 2026
This year
25

Disc Medicines reported that its phase three Apollo study hit all primary and secondary endpoints and plans to launch the porphyria therapy next year; two phase two assets are expected to enter phase three studies.

View
Proposed Sales
Value
$1.3M
Shares
16.0K
Filed
Nov 10, 2026
View
Earnings & Events
Webcasts Upcoming
Next webcast
Nov 17, 2026
Last webcast
Nov 9, 2026
View
Investor Relations
Latest news
Disc Medicine Reports Third Quart…
Published
Nov 5, 2026
Upcoming events
3
View

Performance

5D 20D 120D MTD YTD
IRON +1.4% +40.8% +17.4% -1.0% +0.7%
SPY +2.6% -1.2% +0.5% -0.2% +10.6%
vs SPY -1.2% +41.9% +16.9% -0.9% -9.9%
Key facts CIK 1816736 CUSIP 254604101 13F (30d) 165 filings 146 filers Visit website Investor relations