Disc Medicines reported that its phase three Apollo study hit all primary and secondary endpoints and plans to launch the porphyria therapy next year; two phase two assets are expected to enter phase three studies.
IRON · Disc Medicine, Inc.
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Disc Medicine reported positive APOLLO Phase 3 results for bitopertin and plans an NDA resubmission by the end of 2026. Cash, cash equivalents and marketable securities totaled $682.8 million at September 30, 2026, funding is expected into 2030.
Disc Medicine’s APOLLO trial of bitopertin met all primary and secondary endpoints in EPP; NDA resubmission is planned by end of 2026, while approximately $486 million in October 2026 offering proceeds extend cash runway into 2030.
Disc Medicine, Inc. closed an underwritten offering on October 22, 2026 of 6,000,000 common shares at $75.00 per share, with expected net proceeds of approximately $422.4 million. Preliminary cash, cash equivalents and marketable securities were approximately $682.8 million as of September 30, 2026.
Disc Medicine announced positive Phase 3 APOLLO topline results for bitopertin in erythropoietic protoporphyria, meeting all primary and secondary endpoints, and plans to resubmit an NDA to the FDA by end of 2026 with a decision expected by mid-2027.
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At a glance
key data from every section- Filed
- Nov 9, 2026
- This year
- 25
Disc Medicines reported that its phase three Apollo study hit all primary and secondary endpoints and plans to launch the porphyria therapy next year; two phase two assets are expected to enter phase three studies.
ViewPerformance
| 5D | 20D | 120D | MTD | YTD | |
|---|---|---|---|---|---|
| IRON | +1.4% | +40.8% | +17.4% | -1.0% | +0.7% |
| SPY | +2.6% | -1.2% | +0.5% | -0.2% | +10.6% |
| vs SPY | -1.2% | +41.9% | +16.9% | -0.9% | -9.9% |