ERAS · Erasca, Inc. · Holdings

$14.70 +0.08 (+0.55%)

Russell 2000 member Rebalance outlook locked

Market Cap

$5.11B

349.76M

Volume · Oct 20 4.22M Avg daily vol (3M) 4.32M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP → See every holder of ERAS: 13F, 13D and 13G, insiders and funds →

Institutional holdings are being reconciled with SEC filings. Holder totals and changes may be incomplete until reconciliation finishes.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 259

Total Value: $5,338,574,275

Total Shares: 292,498,123

Showing 1–100 of 273 holdings by value · page 1 of 3

Institutional Ownership Trend

21 quarters

Holder Concentration

Across 257 13F filers

Top Holder

8.6%

of institutional value

Top 5

35.7%

of institutional value

Top 10

55.3%

of institutional value

HHI

384

Broadly held

Who Holds ERAS

Last 8 quarters through Sep 30, 2026 (filing window open)

Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.

Jun 30, 2026, the newest closed quarter: 256 filers, like-for-like change +2.5%; actively managed books +0.9%; index-like books +8.3%.

Holder type	Share	Filers	Change	New	Exited
Registered adviser	59.7%	130	-2.3%	32	16
Exempt adviser	3.0%	7	+6.0%	2	2
Adviser	8.8%	9	+6.9%	1	1
Bank	7.6%	15	+21.2%	2	0
Insurer	0.0%	2	-88.4%	1	0
Broker-dealer	0.0%	1	+75.5%	0	0
Benefit plan	0.2%	5	+13.2%	0	0
Non-US	0.9%	6	+63.9%	1	1
Holding company	10.4%	6	+3.7%	0	0
Unknown	9.4%	75	+14.6%	20	8

Style	Share	Filers	Change	New	Exited
Index-like	22.8%	33	+8.3%	1	0
Systematic-like	3.0%	22	-32.9%	6	2
Concentrated	23.3%	30	-7.3%	7	7
Diversified active	50.9%	171	+8.5%	45	19
Not measured	0.0%	0	—	0	0
Unknown	0.0%	0	—	0	0

Turnover	Share	Filers	Change	New	Exited
Low turnover	46.9%	116	+9.8%	21	7
Medium turnover	35.5%	66	-6.5%	14	9
High turnover	11.3%	49	+15.3%	16	10
Unknown	6.3%	25	-11.0%	8	2
Not measured	0.0%	0	—	0	0

Holding horizon	Share	Filers	Change	New	Exited
Short horizon	9.2%	45	+5.3%	15	8
Medium horizon	41.0%	45	-0.1%	10	4
Long horizon	42.4%	142	+18.2%	27	11
Unknown	7.4%	24	-37.8%	7	5
Not measured	0.0%	0	—	0	0

13F book size	Share	Filers	Change	New	Exited
Under $1B	2.6%	51	-22.3%	19	7
$1B to $10B	40.0%	63	-3.5%	17	13
$10B to $100B	12.1%	75	-6.8%	16	6
$100B or more	45.3%	67	+13.8%	7	2
Not measured	0.0%	0	—	0	0

Client base	Share	Filers	Change	New	Exited
Individuals and high net worth	0.6%	41	+119.5%	14	5
Pooled investment vehicles	42.8%	47	-12.2%	11	9
Registered funds and BDCs	13.2%	17	+35.4%	2	0
Pension and profit sharing plans	0.0%	1	-19.4%	0	0
Insurance companies	0.2%	3	+27.7%	0	0
Governments and sovereign funds	0.6%	5	-1.8%	1	1
Other investment advisers	0.0%	4	+74.9%	2	0
Other	0.0%	1	+100.7%	0	0
Diversified	2.0%	9	+45.7%	2	1
Unknown	40.6%	128	+10.7%	27	12

Private funds	Share	Filers	Change	New	Exited
Hedge funds	20.2%	50	-10.9%	10	11
Private equity funds	10.9%	8	-16.6%	0	1
Venture capital funds	7.9%	4	-10.1%	0	1
Real estate funds	0.0%	4	+7.1%	0	1
Securitized asset funds	0.1%	1	+2.8%	0	0
Other private funds	4.2%	11	+193.5%	4	0
Mixed private funds	10.5%	5	+7.0%	2	0
Private funds, type not stated	0.0%	4	+225.1%	3	0
No private funds	8.8%	49	+8.8%	15	4
Unknown	37.4%	120	+11.1%	25	10

Location	Share	Filers	Change	New	Exited
United States	96.4%	206	+0.7%	45	22
Outside the US	3.6%	50	+94.9%	14	6

The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.

How the mix is measured

Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.

Excluded 2 holders with no observed 2026-03-31 13F and 2 holders with no observed 2026-06-30 13F. Compared across CIK changes: JANUS HENDERSON GROUP PLC continues as Jupiter Topco LLC.

Conviction and Crowding

256 13F filers, quarter ended Jun 30, 2026

Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.

Conviction holders

5.47% of filers hold it in their top 10

Mar 31, 2026: 15

Holders above 5%

median weight 0.005%

Mar 31, 2026: 10

Crowding

50.5%

of shares outstanding, 97th percentile

Mar 31, 2026: 51.3%

Private-fund advisers

48.6%

of shares outstanding

Institutional ownership

90.2%

90.3% of the estimated free float

Top 10 holders

57.0%

of 13F shares, Herfindahl 0.040

Active holders

+0.9%

like-for-like share change of active filers

5% stakes on record

0 13D, 6 13G (2 institutional, 3 passive, 1 exempt)

How long holders have held it value-weighted 9.3 quarters

Under 1 year 25.5% 1 to 3 years 50.9% 3 years or more 23.6% Since coverage start 0.000%

Managers in the top fifth by current three-year FundScore alpha were net sellers of $12,300,148 (0 buying, 2 selling).

Estimated Holder Cost Basis

Quarter ended Jun 30, 2026, on that quarter's share basis

Estimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.

Estimated avg cost

$7.44

estimated per share

Mar 31, 2026: $6.16

Quarter-end price

$18.32

implied by 13F values

Estimated gain or loss

+146.1%

price against the estimated cost

Estimated at a loss

0.000%

of costed 13F value

Estimated cost covers 86.3% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.

Shared Holders

Companies ERAS's active holders also own, quarter ended Jun 30, 2026

#	Company	Shared holders	Similarity
1	DNTH Dianthus Therapeutics, Inc. /DE/	20	0.424
2	ELVN Enliven Therapeutics, Inc.	19	0.415
3	TNGX Tango Therapeutics, Inc.	18	0.410
4	SYRE Spyre Therapeutics, Inc.	18	0.382
5	PRAX Praxis Precision Medicines, Inc.	17	0.360
6	SVRA Savara Inc	13	0.349
7	AVTX Avalo Therapeutics, Inc.	14	0.346
8	MBX MBX Biosciences, Inc.	13	0.344
9	ACHV Achieve Life Sciences, Inc.	9	0.337
10	ORKA Oruka Therapeutics, Inc.	16	0.330

Shareholder Targets

13F filers that own its peers but not ERAS, quarter ended Jun 30, 2026

Found through its holder-overlap peers: DNTH, ELVN, TNGX, SYRE, PRAX, SVRA, AVTX, MBX, ACHV, ORKA, GPCR, RLMD, TARS, COGT, SION, AMLX, MLYS, NERV, DSGN, SABS. 511 filers in all.

#	Filer	In peers	Of book	Largest peers
1	PERCEPTIVE ADVISORS LLC Registered adviser, Diversified active	$1,522,787,971 9 held	24.6%	PRAX, SYRE, AMLX
2	Polar Capital Holdings Plc Registered adviser, Diversified active	$1,090,331,740 11 held	3.08%	ELVN, COGT, ORKA
3	TCG Crossover Management, LLC Unknown, Diversified active	$1,083,842,414 8 held	26.1%	TNGX, COGT, SYRE
4	Deep Track Capital, LP Adviser, Diversified active	$1,050,944,819 8 held	16.0%	GPCR, TARS, ORKA
5	DEERFIELD MANAGEMENT COMPANY, L.P. Registered adviser, Diversified active	$1,035,561,509 8 held	17.6%	PRAX, COGT, TNGX
6	ADAGE CAPITAL PARTNERS GP, L.L.C. Registered adviser, Diversified active	$982,970,241 14 held	1.38%	PRAX, TNGX, SYRE
7	Fairmount Funds Management LLC Registered adviser, Concentrated	$907,111,371 4 held	60.0%	ORKA, DNTH, COGT
8	Driehaus Capital Management LLC Registered adviser, Diversified active	$884,804,755 10 held	5.14%	PRAX, SYRE, GPCR
9	BAKER BROS. ADVISORS LP Registered adviser, Concentrated	$869,781,249 8 held	4.37%	PRAX, DNTH, GPCR
10	RA CAPITAL MANAGEMENT, L.P. Registered adviser, Concentrated	$826,870,170 5 held	7.28%	SION, MLYS, ORKA

Fund Ownership of ERAS by Fund Type

Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026

Index funds and index ETFs hold 11.34% of shares outstanding.

Fund type	Of shares outstanding	Change	Shares	Funds
Index funds	2.23%	+0.47 pp	7,804,134	60
Index ETFs	9.11%	+1.11 pp	31,855,174	35
Active ETFs	0.59%	-0.09 pp	2,051,064	17
Active funds	9.70%	+3.12 pp	33,925,464	119
Unclassified	0.02%	+0.02 pp	70,859	6
All registered funds	21.65%	+4.63 pp	75,706,695	237

How fund types are measured

Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.

Holder type: Registered adviser 133 Exempt adviser 7 Adviser 9 Bank 15 Insurer 2 Broker-dealer 1 Benefit plan 5 Non-US 6 Holding company 6 Unknown 75

Showing 100 of 273

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Frazier Life Sciences Management, L.P.

$457,545,444

8.57%

24,975,188

T. Rowe Price Investment Management, Inc.

$388,124,570

7.27%

21,185,839

BlackRock, Inc.

$387,543,949

7.26%

21,154,146

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	466,088	$8,538,732	2.2%	Sole
BlackRock Investment Management (Australia) Ltd	460	$8,427	0.0%	Sole
BlackRock Asset Management Canada Ltd	43,299	$793,237	0.2%	Sole
BlackRock Investment Management, LLC	598,178	$10,958,620	2.8%	Sole
BLACKROCK ADVISORS LLC	1,724,322	$31,589,579	8.2%	Sole
BlackRock Fund Advisors	9,185,660	$168,281,291	43.4%	Sole
BlackRock Institutional Trust Company, N.A.	6,836,234	$125,239,806	32.3%	Sole
BlackRock Japan Co. Ltd	5,156	$94,457	0.0%	Sole
BlackRock Fund Managers Ltd.	27,900	$511,128	0.1%	Sole
BlackRock Investment Management (UK) Ltd.	112,066	$2,053,049	0.5%	Sole
BlackRock (Netherlands) B.V.	6,185	$113,309	0.0%	Sole
BlackRock Asset Management Ireland Ltd	451,258	$8,267,046	2.1%	Sole
BlackRock (Luxembourg) S.A.	979,508	$17,944,586	4.6%	Sole
BlackRock Asset Management Schweiz AG	28,422	$520,691	0.1%	Sole
Aperio Group, LLC	689,410	$12,629,991	3.3%	Sole

RTW INVESTMENTS, LP

$328,784,533

6.16%

17,946,754

Venrock Adviser, LLC

$327,777,995

6.14%

17,891,812

STATE STREET CORP

$223,221,047

4.18%

12,184,555

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	12,184,555	$223,221,047	100.0%	Defined

Logos Global Management LP

$222,588,000

4.17%

12,150,000

VANGUARD CAPITAL MANAGEMENT LLC

$208,888,285

3.91%

11,402,199

Siren, L.L.C.

$208,807,347

3.91%

11,397,781

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	11,397,781	$208,807,347	100.0%	Defined

Paradigm Biocapital Advisors LP

$174,956,000

3.28%

9,550,000

ARCH Venture Management, LLC

$129,917,324

2.43%

7,091,557

GEODE CAPITAL MANAGEMENT, LLC

$119,106,123

2.23%

6,501,426

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	827,249	$15,155,201	12.7%	Defined
Held directly	5,674,177	$103,950,922	87.3%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$114,912,346

2.15%

6,272,508

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	285,389	$5,228,326	4.5%	Defined
Held directly	5,987,119	$109,684,020	95.5%	Sole

Cormorant Asset Management, LP

$109,920,000

2.06%

6,000,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Chen Bihua	6,000,000	$109,920,000	100.0%	Defined

Affinity Asset Advisors, LLC

$96,180,000

1.80%

5,250,000

Vivo Capital, LLC

$75,614,187

1.42%

4,127,412

ALLIANCEBERNSTEIN L.P.

$75,453,008

1.41%

4,118,614

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	4,118,614	$75,453,008	100.0%	Defined

GOLDMAN SACHS GROUP INC

$70,021,109

1.31%

3,822,113

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	3,364,390	$61,635,624	88.0%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	457,723	$8,385,485	12.0%	Defined

Caption Management, LLC

$68,535,120

1.28%

3,741,000

Assenagon Asset Management S.A.

$60,521,347

1.13%

4,128,332

BANK OF AMERICA CORP /DE/

$55,852,860

1.05%

3,048,737

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	2,598,716	$47,608,477	85.2%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	252,468	$4,625,213	8.3%	Defined
BOFA SECURITIES, INC.	197,553	$3,619,170	6.5%	Defined

FMR LLC

$52,824,198

0.99%

2,883,417

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	2,877,376	$52,713,528	99.8%	Defined
STRATEGIC ADVISERS LLC	635	$11,633	0.0%	Defined
FIAM LLC	5,406	$99,037	0.2%	Defined

a16z Capital Management, L.L.C.

$52,441,000

0.98%

2,862,500

Woodline Partners LP

$51,879,803

0.97%

2,831,867

JENNISON ASSOCIATES LLC

$51,083,707

0.96%

2,788,412

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	2,788,412	$51,083,707	100.0%	Defined

Soleus Capital Management, L.P.

$49,464,000

0.93%

2,700,000

VANGUARD PORTFOLIO MANAGEMENT LLC

$43,782,308

0.82%

2,389,864

SAMLYN CAPITAL, LLC

$41,347,982

0.77%

2,256,986

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SAMLYN ONSHORE FUND, LP joint	363,964	$6,667,820	16.1%	Defined
Samlyn Offshore Master Fund, Ltd.	861,485	$15,782,405	38.2%	Defined
Samlyn Net Neutral Master Fund, Ltd.	801,872	$14,690,295	35.5%	Defined
Samlyn Long Alpha Master Fund, Ltd.	229,665	$4,207,462	10.2%	Defined

BNP PARIBAS ARBITRAGE, SA

$37,410,062

0.70%

2,042,034

NORTHERN TRUST CORP

$35,872,755

0.67%

1,958,120

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	1,805,936	$33,084,746	92.2%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	121,141	$2,219,302	6.2%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	31,043	$568,707	1.6%	Other

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$35,628,552

0.67%

1,944,790

VICTORY CAPITAL MANAGEMENT INC

$35,475,983

0.66%

1,936,462

Nuveen, LLC

$33,740,584

0.63%

1,841,735

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	97,567	$1,787,427	5.3%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	282,316	$5,172,029	15.3%	Defined
TEACHERS ADVISORS, LLC joint	1,461,852	$26,781,128	79.4%	Defined

DIMENSIONAL FUND ADVISORS LP

$32,316,111

0.61%

1,763,980

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	25,157	$460,876	1.4%	Defined
DFA Australia Ltd.	24,640	$451,404	1.4%	Defined
Dimensional Ireland Ltd	97,574	$1,787,555	5.5%	Defined
Held directly	1,616,609	$29,616,276	91.6%	Sole

VANGUARD FIDUCIARY TRUST CO

$31,107,195

0.58%

1,697,991

UBS Group AG

$29,250,847

0.55%

1,596,662

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	1,583,258	$29,005,286	99.2%	Defined
UBS Switzerland AG	10,000	$183,200	0.6%	Defined
UBS Securities LLC	3,404	$62,361	0.2%	Defined

STEMPOINT CAPITAL LP

$28,687,526

0.54%

1,565,913

Rock Springs Capital Management LP

$25,687,388

0.48%

1,402,150

Evergreen Quality Fund GP, Ltd.

$25,195,496

0.47%

1,375,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HHLR ADVISORS, LTD.	1,375,300	$25,195,496	100.0%	Other

RENAISSANCE TECHNOLOGIES LLC

$25,078,577

0.47%

1,368,918

FRED ALGER MANAGEMENT, LLC

$23,970,895

0.45%

1,308,455

SILVERARC CAPITAL MANAGEMENT, LLC

$23,138,636

0.43%

1,263,026

Point72 Asset Management, L.P.

$22,848,758

0.43%

1,247,203

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$22,780,920

0.43%

1,243,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	1,243,500	$22,780,920	100.0%	Other

First Turn Management, LLC

$22,381,928

0.42%

1,221,721

FEDERATED HERMES, INC.

$19,827,039

0.37%

1,082,262

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED EQUITY MANAGEMENT CO OF PENNSYLVANIA	43,972	$805,567	4.1%	Defined
FEDERATED GLOBAL INVESTMENT MANAGEMENT CORP	315,600	$5,781,792	29.2%	Defined
FEDERATED MDTA LLC	722,690	$13,239,680	66.8%	Defined

Caption Management, LLC

$19,075,242

0.36%

1,041,225

Integral Health Asset Management, LLC

$18,320,000

0.34%

1,000,000

D. E. Shaw & Co., Inc.

$17,396,488

0.33%

949,590

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	936,290	$17,152,832	98.6%	Defined
D. E. Shaw Investment Management, L.L.C. joint	13,300	$243,656	1.4%	Defined

MILLENNIUM MANAGEMENT LLC

$16,667,792

0.31%

909,814

Invesco Ltd.

$15,838,132

0.30%

864,527

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	30,789	$564,053	3.6%	Defined
Invesco Trust Co joint	79,646	$1,459,114	9.2%	Defined
Invesco Capital Management LLC	754,092	$13,814,965	87.2%	Defined

MARSHALL WACE, LLP

$13,868,074

0.26%

756,991

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	756,991	$13,868,074	100.0%	Other

Caption Management, LLC

$13,245,360

0.25%

723,000

SCHRODER INVESTMENT MANAGEMENT GROUP

$13,185,361

0.25%

719,725

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	718,554	$13,163,909	99.8%	Sole
Schroder Investment Management North America Inc.	1,171	$21,452	0.2%	Sole

CITIGROUP INC

$13,071,942

0.24%

713,534

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	713,534	$13,071,942	100.0%	Defined

Capital World Investors

$12,908,308

0.24%

704,602

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CAPITAL GROUP COMPANIES INC joint	704,602	$12,908,308	100.0%	Defined

JANE STREET GROUP, LLC

$12,752,552

0.24%

696,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	696,100	$12,752,552	100.0%	Defined

AQR CAPITAL MANAGEMENT LLC

$12,484,729

0.23%

681,481

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	66	$1,209	0.0%	Other
Compound Planning, Inc.	4	$73	0.0%	Other
Arax Advisory Partners	7,209	$132,068	1.1%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	2,774	$50,819	0.4%	Other
Stokes Family Office, LLC	4,584	$83,978	0.7%	Other
Held directly	666,844	$12,216,582	97.9%	Defined

TD Asset Management Inc

$12,112,304

0.23%

661,152

Balyasny Asset Management L.P.

$12,057,766

0.23%

658,175

WELLINGTON MANAGEMENT GROUP LLP

$12,005,057

0.22%

655,298

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	339,800	$6,225,136	51.9%	Defined
Wellington Managment Canada LLC	2,018	$36,969	0.3%	Defined
Wellington Trust Company, NA joint	285,148	$5,223,911	43.5%	Defined
Wellington Management Australia Pty Ltd	23,712	$434,403	3.6%	Defined
Wellington Management Europe GmbH	4,620	$84,638	0.7%	Defined

JANE STREET GROUP, LLC

$11,433,639

0.21%

624,107

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	537,943	$9,855,115	86.2%	Defined
Jane Street Global Trading, LLC	86,164	$1,578,524	13.8%	Defined

MORGAN STANLEY

$11,284,676

0.21%

615,976

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	809	$14,820	0.1%	Defined
MORGAN STANLEY & CO. LLC	58,920	$1,079,414	9.6%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	482,087	$8,831,833	78.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	1,349	$24,713	0.2%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	72,811	$1,333,896	11.8%	Defined

Balyasny Asset Management L.P.

$10,992,000

0.21%

600,000

Bank of New York Mellon Corp

$10,405,261

0.19%

567,973

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNY Mellon Trust of Delaware joint	270	$4,946	0.0%	Defined
Mellon Investments Corporation joint	184,045	$3,371,703	32.4%	Defined
The Bank of New York Mellon	372,060	$6,816,139	65.5%	Defined
BNY Mellon, NA joint	11,596	$212,437	2.0%	Defined
Held directly	2	$36	0.0%	Defined

AMERIPRISE FINANCIAL INC

$10,038,169

0.19%

547,935

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	547,935	$10,038,169	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$9,649,144

0.18%

526,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	526,700	$9,649,144	100.0%	Other

JPMORGAN CHASE & CO

$9,171,064

0.17%

500,604

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	105,776	$1,937,816	21.1%	Defined
J.P. Morgan Investment Management Inc.	388,205	$7,111,915	77.5%	Defined
J.P. Morgan Securities plc	6,623	$121,333	1.3%	Defined

ORBIMED ADVISORS LLC

$9,084,888

0.17%

495,900

Polymer Capital Management (HK) LTD

$8,757,326

0.16%

478,020

KVP Capital Advisors, LP

$8,335,600

0.16%

455,000

Spruce Street Capital LP

$7,740,987

0.15%

422,543

Creative Planning

$7,435,702

0.14%

405,879

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	3,865	$70,806	1.0%	Defined
Held directly	402,014	$7,364,896	99.0%	Sole

Pictet Asset Management Holding SA

$7,205,036

0.13%

393,288

Cinctive Capital Management LP

$7,174,881

0.13%

391,642

CITADEL ADVISORS LLC

$6,961,600

0.13%

380,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	380,000	$6,961,600	100.0%	Defined

Rhenman & Partners Asset Management AB

$6,393,680

0.12%

349,000

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$6,369,057

0.12%

347,656

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	347,656	$6,369,057	100.0%	Defined

VOYA INVESTMENT MANAGEMENT LLC

$6,244,316

0.12%

340,847

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	340,847	$6,244,316	100.0%	Defined

EcoR1 Capital, LLC

$6,045,600

0.11%

330,000

ROYAL BANK OF CANADA

$5,741,431

0.11%

313,397

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Global Asset Management Inc.	250,000	$4,580,000	79.8%	Defined
RBC CMA LTD.	6,080	$111,385	1.9%	Defined
RBC Capital Markets, LLC	57,023	$1,044,661	18.2%	Defined
RBC Dominion Securities Inc.	24	$439	0.0%	Defined
Held directly	270	$4,946	0.1%	Sole

Swiss National Bank

$5,714,008

0.11%

311,900

Seven Fleet Capital Management LP

$5,642,687

0.11%

308,007

WELLS FARGO & COMPANY/MN

$5,322,381

0.10%

290,523

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	182,600	$3,345,232	62.9%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	2,923	$53,549	1.0%	Defined
WELLS FARGO CLEARING SERVICES, LLC	105,000	$1,923,600	36.1%	Defined

Longaeva Partners L.P.

$5,245,419

0.10%

286,322

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Balyasny Asset Management L.P.	286,322	$5,245,419	100.0%	Other

SIMPLEX TRADING, LLC

$5,074,420

0.10%

276,988

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$4,875,683

0.09%

266,140

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	3,207	$58,752	1.2%	Defined
UBS Asset Management Switzerland AG	210,113	$3,849,270	78.9%	Sole
UBS Asset Management (UK) Ltd.	22,077	$404,450	8.3%	Defined
Held directly	30,743	$563,211	11.6%	Defined

E Fund Management Co., Ltd.

$4,861,779

0.09%

265,381

ACUTA CAPITAL PARTNERS, LLC

$4,858,445

0.09%

265,199

Parkman Healthcare Partners LLC

$4,739,090

0.09%

258,684

RHUMBLINE ADVISERS

$4,696,643

0.09%

256,367

CITADEL ADVISORS LLC

$4,354,664

0.08%

237,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	237,700	$4,354,664	100.0%	Defined

DEUTSCHE BANK AG\

$4,072,645

0.08%

222,306

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	3,766	$68,993	1.7%	Defined
DWS Investments UK Ltd	218,540	$4,003,652	98.3%	Defined

Tema ETFs LLC

$3,947,087

0.07%

269,242

ArrowMark Colorado Holdings LLC

$3,864,182

0.07%

210,927

Rafferty Asset Management, LLC

$3,782,402

0.07%

206,463

Man Group plc

$3,710,770

0.07%

202,553

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AHL Partners LLP	202,553	$3,710,770	100.0%	Defined

Tidal Investments LLC

$3,342,264

0.06%

182,438

Moody Aldrich Partners LLC

$3,259,842

0.06%

177,939

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$3,229,321

0.06%

176,273

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Key facts CIK 1761918 CUSIP 29479A108 13F (30d) 19 filings 19 filers Visit website Investor relations