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  • PRAX Praxis Precision Medicines, Inc.

PRAX

Praxis Precision Medicines, Inc.

Company with tickers: PRAX

CIK
1689548
CUSIP
74006W207
Shares Outstanding
27,878,774
Price History Institutional Holders Short Volume Short Interest Fails to Deliver Financials SEC Filings Earnings Calls Insider Trades Congressional Trades
Holders: 289
Total Value: $9,424,372,093
Total Shares: 29,250,977
Showing 1–100 of 300 holdings by value · page 1 of 3

Institutional Ownership Trend

10 quarters

Holder Concentration

Across 289 13F filers · Δ vs Dec 31, 2025
Top Holder
11.8%
+1.1 pts
Top 5
42.6%
+9.7 pts
Top 10
61.2%
+11.8 pts
HHI
495
Broadly held +126

Quarterly Activity

vs Dec 31, 2025
New
283
Increased
3
Decreased
2
Sold Out
252
Unchanged
1
Holder count: +31
Institutional value: +5.9%
Shares held: -3.1%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds
Mega HSBC HOLDINGS PLC +809 1,634
Large Rockefeller Capital Management L.P. +253 315
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. +145 424

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds
Large Candriam S.C.A. −46,962 63,628
Mega GOLDMAN SACHS GROUP INC −5,450 710,734

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD)
Mega JANUS HENDERSON GROUP PLC 3,458,863 $1,114,411,067
Large Orbis Allan Gray Ltd 2,472,480 $796,608,330
Mega BlackRock, Inc. 2,324,929 $749,068,868
Mega FMR LLC 2,160,943 $696,234,223
Mid PERCEPTIVE ADVISORS LLC 2,035,986 $655,974,329

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD)
Mega JANUS HENDERSON GROUP PLC 3,240,086 $954,982,946
Mega BlackRock, Inc. 2,078,500 $612,617,081
Mid PERCEPTIVE ADVISORS LLC 1,995,986 $588,296,913
Mega FMR LLC 1,358,675 $400,455,868
Large Orbis Allan Gray Ltd 1,255,162 $369,946,447
100 of 100 shown
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Action
Mega JANUS HENDERSON GROUP PLC $1,114,411,067 11.82% 3,458,863 View
Large Orbis Allan Gray Ltd $796,608,330 8.45% 2,472,480 View
Mega BlackRock, Inc. $749,068,868 7.95% 2,324,929 View
Mega FMR LLC $696,234,223 7.39% 2,160,943 View
Mid PERCEPTIVE ADVISORS LLC $655,974,329 6.96% 2,035,986 View
Large BAKER BROS. ADVISORS LP $564,862,863 5.99% 1,753,198 View
Mid DEERFIELD MANAGEMENT COMPANY, L.P. $310,382,058 3.29% 963,351 View
Large Driehaus Capital Management LLC $305,830,802 3.25% 949,225 View
Mid Cormorant Asset Management, LP $285,299,245 3.03% 885,500 View
Mega STATE STREET CORP $284,892,641 3.02% 884,238 View
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $262,822,948 2.79% 815,739 View
Mega GOLDMAN SACHS GROUP INC $228,991,385 2.43% 710,734 View
Mega GEODE CAPITAL MANAGEMENT, LLC $209,714,759 2.23% 650,904 View
Mega PRICE T ROWE ASSOCIATES INC /MD/ $203,254,205 2.16% 630,852 View
Mega BANK OF AMERICA CORP /DE/ $172,244,061 1.83% 534,604 View
Mid RA CAPITAL MANAGEMENT, L.P. $120,430,433 1.28% 373,787 View
Mid Hood River Capital Management LLC $115,543,133 1.23% 358,618 View
Mid Vivo Capital, LLC $109,188,580 1.16% 338,895 View
Mid Soleus Capital Management, L.P. $106,489,272 1.13% 330,517 View
Large Pictet Asset Management Holding SA $92,353,830 0.98% 286,644 View
Mid Logos Global Management LP $91,824,150 0.97% 285,000 View
Mega FRANKLIN RESOURCES INC $88,964,068 0.94% 276,123 View
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $69,414,868 0.74% 215,447 View
Large Woodline Partners LP $64,442,188 0.68% 200,013 View
Large Caption Management, LLC $64,438,000 0.68% 200,000 View
Mega T. Rowe Price Investment Management, Inc. $56,459,609 0.60% 175,237 View
Mega WELLINGTON MANAGEMENT GROUP LLP $56,173,823 0.60% 174,350 View
Mid ORBIMED ADVISORS LLC $55,577,775 0.59% 172,500 View
Large Aberdeen Group plc $55,572,619 0.59% 172,484 View
Mid Affinity Asset Advisors, LLC $54,772,300 0.58% 170,000 View
Mega BNP PARIBAS ARBITRAGE, SA $46,099,589 0.49% 143,082 View
Mega AMERICAN CENTURY COMPANIES INC $41,322,156 0.44% 128,254 View
Large Qube Research & Technologies Ltd $41,313,779 0.44% 128,228 View
Mid ArrowMark Colorado Holdings LLC $37,970,413 0.40% 117,851 View
Mid 683 Capital Management, LLC $36,310,813 0.39% 112,700 View
Mega UBS Group AG $34,940,216 0.37% 108,446 View
Small Velan Capital Investment Management LP $32,470,630 0.34% 100,781 View
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $32,122,343 0.34% 99,700 View
Mega Bank of New York Mellon Corp $28,045,670 0.30% 87,047 View
Small ACUTA CAPITAL PARTNERS, LLC $27,354,253 0.29% 84,901 View
Large MetLife Investment Management, LLC $26,074,836 0.28% 80,930 View
Mega JPMORGAN CHASE & CO $25,833,191 0.27% 80,180 View
Large Alyeska Investment Group, L.P. $23,255,029 0.25% 72,178 View
Mega Nuveen, LLC $23,211,533 0.25% 72,043 View
Mid Ikarian Capital, LLC $23,062,682 0.24% 71,581 View
Small SILVERARC CAPITAL MANAGEMENT, LLC $23,053,338 0.24% 71,552 View
Large Ensign Peak Advisors, Inc $22,032,318 0.23% 68,383 View
Micro 72 Investment Holdings, LLC $21,242,953 0.23% 65,933 View
Mid Sofinnova Investments, Inc. $20,517,059 0.22% 63,680 View
Large Candriam S.C.A. $20,500,305 0.22% 63,628 View
Mega Invesco Ltd. $19,781,499 0.21% 61,397 View
Mega AQR CAPITAL MANAGEMENT LLC $18,898,372 0.20% 58,656 View
Mega DEUTSCHE BANK AG\ $18,615,814 0.20% 57,779 View
Small STEMPOINT CAPITAL LP $18,128,664 0.19% 56,267 View
Mid FRONTIER CAPITAL MANAGEMENT CO LLC $17,193,669 0.18% 53,365 View
Mega JANE STREET GROUP, LLC $15,336,244 0.16% 47,600 View
Large Universal- Beteiligungs- und Servicegesellschaft mbH $15,282,116 0.16% 47,432 View
Mega JANE STREET GROUP, LLC $15,110,711 0.16% 46,900 View
Mega Swiss National Bank $15,046,273 0.16% 46,700 View
Small Boxer Capital Management, LLC $14,967,980 0.16% 46,457 View
Small Exome Asset Management LLC $14,649,657 0.16% 45,469 View
Large MARSHALL WACE, LLP $14,546,556 0.15% 45,149 View
Small KVP Capital Advisors, LP $13,821,951 0.15% 42,900 View
Small First Turn Management, LLC $13,674,065 0.15% 42,441 View
Mega California Public Employees Retirement System $13,584,496 0.14% 42,163 View
Mega CITADEL ADVISORS LLC $13,177,571 0.14% 40,900 View
Mega CANADA PENSION PLAN INVESTMENT BOARD $12,929,484 0.14% 40,130 View
Mid Integral Health Asset Management, LLC $12,887,600 0.14% 40,000 View
Mid EVENTIDE ASSET MANAGEMENT, LLC $12,449,421 0.13% 38,640 View
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $12,289,934 0.13% 38,145 View
Mid SummitTX Capital, L.P. $11,868,835 0.13% 36,838 View
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $11,566,621 0.12% 35,900 View
Mega CITADEL ADVISORS LLC $11,469,964 0.12% 35,600 View
Small PFM Health Sciences, LP $11,417,769 0.12% 35,438 View
Mega TD Asset Management Inc $11,323,689 0.12% 35,146 View
Mid Burkehill Global Management, LP $11,276,650 0.12% 35,000 View
Mega FIRST TRUST ADVISORS LP $10,740,203 0.11% 33,335 View
Small B Group, Inc. $10,708,629 0.11% 33,237 View
Mega RHUMBLINE ADVISERS $10,593,285 0.11% 32,879 View
Small Ally Bridge Group (NY) LLC $10,571,053 0.11% 32,810 View
Mega AMERIPRISE FINANCIAL INC $10,058,771 0.11% 31,220 View
Mega DIMENSIONAL FUND ADVISORS LP $10,039,762 0.11% 31,161 View
Large PRUDENTIAL FINANCIAL INC $9,830,016 0.10% 30,510 View
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE $9,695,663 0.10% 30,093 View
Large LORD, ABBETT & CO. LLC $9,542,945 0.10% 29,619 View
Large SEI INVESTMENTS CO $9,512,659 0.10% 29,525 View
Large VOYA INVESTMENT MANAGEMENT LLC $9,064,492 0.10% 28,134 View
Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $8,938,838 0.09% 27,744 View
Mega ALLIANCEBERNSTEIN L.P. $8,924,663 0.09% 27,700 View
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $8,852,814 0.09% 27,477 View
Small HighVista Strategies LLC $8,481,007 0.09% 26,323 View
Mega NEUBERGER BERMAN GROUP LLC $8,364,052 0.09% 25,960 View
Small University of Wisconsin Foundation $8,124,020 0.09% 25,215 View
Large CONGRESS ASSET MANAGEMENT CO $8,002,877 0.08% 24,839 View
Mid Susquehanna Portfolio Strategies, LLC $7,491,239 0.08% 23,251 View
Large Russell Investments Group, Ltd. $7,446,452 0.08% 23,112 View
Small Ishara Investments LP $7,265,384 0.08% 22,550 View
Small Moody Aldrich Partners LLC $6,987,656 0.07% 21,688 View
Mid Atom Investors LP $6,829,139 0.07% 21,196 View
Small Ishara Investments LP $6,604,895 0.07% 20,500 View
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